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Items: 26

1.

Boron-based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center.

Freund YR, Akama T, Alley MR, Antunes J, Dong C, Jarnagin K, Kimura R, Nieman JA, Maples KR, Plattner JJ, Rock F, Sharma R, Singh R, Sanders V, Zhou Y.

FEBS Lett. 2012 Sep 21;586(19):3410-4. doi: 10.1016/j.febslet.2012.07.058. Epub 2012 Jul 25.

2.

Translational research involving oxidative stress and diseases of aging.

Floyd RA, Towner RA, He T, Hensley K, Maples KR.

Free Radic Biol Med. 2011 Sep 1;51(5):931-41. doi: 10.1016/j.freeradbiomed.2011.04.014. Epub 2011 Apr 14. Review.

3.

Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis.

Akama T, Baker SJ, Zhang YK, Hernandez V, Zhou H, Sanders V, Freund Y, Kimura R, Maples KR, Plattner JJ.

Bioorg Med Chem Lett. 2009 Apr 15;19(8):2129-32. doi: 10.1016/j.bmcl.2009.03.007. Epub 2009 Mar 9.

PMID:
19303290
4.

Novel semisynthetic derivative of antibiotic Eremomycin active against drug-resistant gram-positive pathogens including Bacillus anthracis.

Maples KR, Wheeler C, Ip E, Plattner JJ, Chu D, Zhang YK, Preobrazhenskaya MN, Printsevskaya SS, Solovieva SE, Olsufyeva EN, Heine H, Lovchik J, Lyons CR.

J Med Chem. 2007 Jul 26;50(15):3681-5. Epub 2007 Jul 3.

PMID:
17608397
5.

Identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases.

Baker SJ, Akama T, Zhang YK, Sauro V, Pandit C, Singh R, Kully M, Khan J, Plattner JJ, Benkovic SJ, Lee V, Maples KR.

Bioorg Med Chem Lett. 2006 Dec 1;16(23):5963-7. Epub 2006 Sep 25.

PMID:
16997550
6.

Nitrone-related therapeutics: potential of NXY-059 for the treatment of acute ischaemic stroke.

Maples KR, Green AR, Floyd RA.

CNS Drugs. 2004;18(15):1071-84. Review.

PMID:
15581379
7.

NXY-059 maintains Akt activation and inhibits release of cytochrome C after focal cerebral ischemia.

Yoshimoto T, Kanakaraj P, Ying Ma J, Cheng M, Kerr I, Malaiyandi L, Watson JA, Siesjö BK, Maples KR.

Brain Res. 2002 Aug 30;947(2):191-8.

PMID:
12176160
8.

NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat.

Zhao Z, Cheng M, Maples KR, Ma JY, Buchan AM.

Brain Res. 2001 Aug 3;909(1-2):46-50.

PMID:
11478919
9.

Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059.

Maples KR, Ma F, Zhang YK.

Free Radic Res. 2001 Apr;34(4):417-26.

PMID:
11328677
10.

Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.

Kuroda S, Tsuchidate R, Smith ML, Maples KR, Siesjö BK.

J Cereb Blood Flow Metab. 1999 Jul;19(7):778-87.

PMID:
10413033
12.
13.

Particle clearance and histopathology in lungs of F344/N rats and B6C3F1 mice inhaling nickel oxide or nickel sulfate.

Benson JM, Chang IY, Cheng YS, Hahn FF, Kennedy CH, Barr EB, Maples KR, Snipes MB.

Fundam Appl Toxicol. 1995 Dec;28(2):232-44.

PMID:
8835233
14.

A comparison of the inflammatory response of the lung to inhaled versus instilled particles in F344 rats.

Henderson RF, Driscoll KE, Harkema JR, Lindenschmidt RC, Chang IY, Maples KR, Barr EB.

Fundam Appl Toxicol. 1995 Feb;24(2):183-97.

PMID:
7737430
15.

Polycyclic aromatic hydrocarbons decrease intracellular glutathione levels in the A20.1 murine B cell lymphoma.

Yuan JW, Krieger JA, Maples KR, Born JL, Burchiel SW.

Fundam Appl Toxicol. 1994 Oct;23(3):336-41.

PMID:
7835533
16.

Species differences in the metabolism of 1,3-butadiene in vivo.

Henderson RF, Bechtold WE, Sabourin PJ, Maples KR, Dahl AR.

IARC Sci Publ. 1993;(127):57-64.

PMID:
8070887
17.
18.

Glutathione release by pulmonary alveolar macrophages in response to particles in vitro.

Boehme DS, Maples KR, Henderson RF.

Toxicol Lett. 1992 Jan;60(1):53-60.

PMID:
1311468
19.

Blood levels of propylene oxide during propylene inhalation and effect on hepatic and nasal cytochrome P-450 concentrations.

Maples KR, Dahl AR.

Drug Metab Dispos. 1991 Jul-Aug;19(4):835-7. No abstract available.

PMID:
1680663
20.

The nitric oxide/heme protein complex as a biologic marker of exposure to nitrogen dioxide in humans, rats, and in vitro models.

Maples KR, Sandström T, Su YF, Henderson RF.

Am J Respir Cell Mol Biol. 1991 Jun;4(6):538-43.

PMID:
1647179
21.

In vivo thiyl free radical formation from hemoglobin following administration of hydroperoxides.

Maples KR, Kennedy CH, Jordan SJ, Mason RP.

Arch Biochem Biophys. 1990 Mar;277(2):402-9.

PMID:
2155581
22.
23.

A comparison of cobalt(II) and iron(II) hydroxyl and superoxide free radical formation.

Kadiiska MB, Maples KR, Mason RP.

Arch Biochem Biophys. 1989 Nov 15;275(1):98-111.

PMID:
2554814
24.

In vivo rat hemoglobin thiyl free radical formation following administration of phenylhydrazine and hydrazine-based drugs.

Maples KR, Jordan SJ, Mason RP.

Drug Metab Dispos. 1988 Nov-Dec;16(6):799-803.

PMID:
2907456
25.

In vivo rat hemoglobin thiyl free radical formation following phenylhydrazine administration.

Maples KR, Jordan SJ, Mason RP.

Mol Pharmacol. 1988 Mar;33(3):344-50.

PMID:
2832722
26.

Free radical metabolite of uric acid.

Maples KR, Mason RP.

J Biol Chem. 1988 Feb 5;263(4):1709-12.

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