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Items: 30


Graft-versus-host disease reduces lymph node display of tissue-restricted self-antigens and promotes autoimmunity.

Dertschnig S, Evans P, Santos E Sousa P, Manzo T, Ferrer IR, Stauss HJ, Bennett CL, Chakraverty R.

J Clin Invest. 2020 Jan 9. pii: 133102. doi: 10.1172/JCI133102. [Epub ahead of print]


Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA.

Science. 2018 Jan 5;359(6371):97-103. doi: 10.1126/science.aan4236. Epub 2017 Nov 2.


T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

Manzo T, Sturmheit T, Basso V, Petrozziello E, Hess Michelini R, Riba M, Freschi M, Elia AR, Grioni M, Curnis F, Protti MP, Schumacher TN, Debets R, Swartz MA, Corti A, Bellone M, Mondino A.

Cancer Res. 2017 Feb 1;77(3):658-671. doi: 10.1158/0008-5472.CAN-16-0725. Epub 2016 Nov 21.


3D modeling of human cancer: A PEG-fibrin hydrogel system to study the role of tumor microenvironment and recapitulate the in vivo effect of oncolytic adenovirus.

Del Bufalo F, Manzo T, Hoyos V, Yagyu S, Caruana I, Jacot J, Benavides O, Rosen D, Brenner MK.

Biomaterials. 2016 Apr;84:76-85. doi: 10.1016/j.biomaterials.2016.01.030. Epub 2016 Jan 20.


Depletion of CD11c⁺ cells in the CD11c.DTR model drives expansion of unique CD64⁺ Ly6C⁺ monocytes that are poised to release TNF-α.

Sivakumaran S, Henderson S, Ward S, Sousa PS, Manzo T, Zhang L, Conlan T, Means TK, D'Aveni M, Hermine O, Rubio MT, Chakraverty R, Bennett CL.

Eur J Immunol. 2016 Jan;46(1):192-203. doi: 10.1002/eji.201545789. Epub 2015 Nov 30.


Antigen-specific T cell therapies for cancer.

Manzo T, Heslop HE, Rooney CM.

Hum Mol Genet. 2015 Oct 15;24(R1):R67-73. doi: 10.1093/hmg/ddv270. Epub 2015 Jul 9. Review.


PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation.

Platonova N, Manzo T, Mirandola L, Colombo M, Calzavara E, Vigolo E, Cermisoni GC, De Simone D, Garavelli S, Cecchinato V, Lazzari E, Neri A, Chiaramonte R.

Genes Chromosomes Cancer. 2015 Aug;54(8):516-526. doi: 10.1002/gcc.22264. Epub 2015 Jun 6.


Genetic Regulation of Fate Decisions in Therapeutic T Cells to Enhance Tumor Protection and Memory Formation.

Veliça P, Zech M, Henson S, Holler A, Manzo T, Pike R, Santos E Sousa P, Zhang L, Heinz N, Schiedlmeier B, Pule M, Stauss H, Chakraverty R.

Cancer Res. 2015 Jul 1;75(13):2641-52. doi: 10.1158/0008-5472.CAN-14-3283. Epub 2015 Apr 22. Erratum in: Cancer Res. 2015 Dec 15;75(24):5402. Heinz, Niels [added].


G-CSF mobilizes CD34+ regulatory monocytes that inhibit graft-versus-host disease.

D'Aveni M, Rossignol J, Coman T, Sivakumaran S, Henderson S, Manzo T, Santos e Sousa P, Bruneau J, Fouquet G, Zavala F, Alegria-Prévot O, Garfa-Traoré M, Suarez F, Trebeden-Nègre H, Mohty M, Bennett CL, Chakraverty R, Hermine O, Rubio MT.

Sci Transl Med. 2015 Apr 1;7(281):281ra42. doi: 10.1126/scitranslmed.3010435.


OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.

Buchan S, Manzo T, Flutter B, Rogel A, Edwards N, Zhang L, Sivakumaran S, Ghorashian S, Carpenter B, Bennett C, Freeman GJ, Sykes M, Croft M, Al-Shamkhani A, Chakraverty R.

J Immunol. 2015 Jan 1;194(1):125-133. doi: 10.4049/jimmunol.1401644. Epub 2014 Nov 17.


Tumor-targeting vaccination instructs graft-vs.-tumor immune responses.

Manzo T, Michelini RH, Sturmheit T, Basso V, Bellone M, Mondino A.

Oncoimmunology. 2013 Oct 1;2(10):e25996. Epub 2013 Sep 12.


Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T-cell transplantation.

Hess Michelini R, Manzo T, Sturmheit T, Basso V, Rocchi M, Freschi M, Listopad J, Blankenstein T, Bellone M, Mondino A.

Cancer Res. 2013 Aug 1;73(15):4641-52. doi: 10.1158/0008-5472.CAN-12-3464. Epub 2013 Jun 7.


The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells.

Marangoni F, Murooka TT, Manzo T, Kim EY, Carrizosa E, Elpek NM, Mempel TR.

Immunity. 2013 Feb 21;38(2):237-49. doi: 10.1016/j.immuni.2012.09.012. Epub 2013 Jan 11.


Concurrent allorecognition has a limited impact on posttransplant vaccination.

Manzo T, Hess Michelini R, Basso V, Ricupito A, Chai JG, Simpson E, Bellone M, Mondino A.

J Immunol. 2011 Feb 1;186(3):1361-8. doi: 10.4049/jimmunol.1002030. Epub 2011 Jan 5.


Concomitant tumor and minor histocompatibility antigen-specific immunity initiate rejection and maintain remission from established spontaneous solid tumors.

Hess Michelini R, Freschi M, Manzo T, Jachetti E, Degl'Innocenti E, Grioni M, Basso V, Bonini C, Simpson E, Mondino A, Bellone M.

Cancer Res. 2010 May 1;70(9):3505-14. doi: 10.1158/0008-5472.CAN-09-4253. Epub 2010 Apr 13.


Sjögren's syndrome with anticentromere antibodies.

Caramaschi P, Biasi D, Carletto A, Manzo T, Randon M, Zeminian S, Bambara LM.

Rev Rhum Engl Ed. 1997 Dec;64(12):785-8.


Multiple tendon ruptures in a patient affected by anti-SSA/Ro antibody positive rheumatoid arthritis.

Caramaschi P, Biasi D, Carletto A, Manzo T, Randon M, Pacor ML, Bambara LM.

Clin Rheumatol. 1997 Nov;16(6):636-7. No abstract available.


Large artery giant cell arteritis: a diagnosis to remember.

Caramaschi P, Biasi D, Carletto A, Zeminian S, Manzo T, Bambara LM.

Clin Rheumatol. 1997 Mar;16(2):219-20. No abstract available.


A case of parvovirus-B19 adult acute arthritis with some allergic disease clinical features.

Biasi D, Zeminian S, Caramaschi P, Carletto A, Manzo T, Bambara LM.

Clin Rheumatol. 1996 Sep;15(5):508-10.


Two cases of multiple autoimmune disorders in patients with selective IgA deficiency.

Caramaschi P, Biasi D, Randon M, Carletto A, Manzo T, Bambara LM.

Rev Rhum Engl Ed. 1996 Feb;63(2):151-2. No abstract available.


Finger skin temperature in patients affected by Raynaud's phenomenon with or without anticentromere antibody positivity.

Caramaschi P, Biasi D, Carletto A, Manzo T, Randon M, Zeminian S, Bambara LM.

Rheumatol Int. 1996;15(5):217-20.


[Multiple osseous avascular necrosis in a patient with systemic lupus erythematosus with antiphospholipid antibody positivity].

Biasi D, Caramaschi P, Pacor ML, Carletto A, Melchiori S, Manzo T, Bambara LM.

Recenti Prog Med. 1995 Nov;86(11):449-50. Italian. No abstract available.


Clobazam-induced systemic lupus erythematosus.

Caramaschi P, Biasi D, Carletto A, Manzo T, Bambara LM.

Clin Rheumatol. 1995 Jan;14(1):116. No abstract available.


Anticentromere antibody--clinical associations. A study of 44 patients.

Caramaschi P, Biasi D, Manzo T, Carletto A, Poli F, Bambara LM.

Rheumatol Int. 1995;14(6):253-5.


[Liver involvement in systemic lupus erythematosus].

Caramaschi P, Biasi D, Botto M, Carletto A, Manzo T, Bambara LM.

Recenti Prog Med. 1993 Oct;84(10):673-8. Italian.


Appearance of a gallstone in a patient with systemic lupus erythematosus during ursodeoxycholic acid treatment.

Caramaschi P, Biasi D, Botto M, Manzo T, Carletto A, Bambara LM.

Acta Gastroenterol Belg. 1993 Sep-Dec;56(5-6):358. No abstract available.


Immunological and clinical effects of intramuscular rIFN alpha-2a and low dose subcutaneous rIL-2 in patients with advanced malignant melanoma.

Castello G, Comella P, Manzo T, Napolitano M, Parziale AP, Galati MG, Daponte A, Casaretti R, Celentano E, Comella G.

Melanoma Res. 1993 Feb;3(1):43-9.


[Myasthenia gravis, palindromic rheumatism and systemic lupus erythematosus. A clinical case report].

Caramaschi P, Biasi D, Pacor ML, Manzo T, Carletto A, Marchetta A, Frigo A, Bambara LM.

Recenti Prog Med. 1992 Jan;83(1):12-4. Review. Italian.


Plasma and urinary growth hormone and insulin-like growth factor I in children with chronic renal insufficiency.

Perrone L, Sinisi AA, Criscuolo T, Manzo T, Maresca G, Bellastella A, del Gado R.

Child Nephrol Urol. 1990;10(2):72-5.


Male pseudohermaphroditism due to 3 beta-hydroxysteroid dehydrogenase-isomerase deficiency associated with atrial septal defect.

Perrone L, Criscuolo T, Sinisi AA, Graziani M, Manzo T, Sicuranza R, Bellastella A, Faggiano M.

Acta Endocrinol (Copenh). 1985 Dec;110(4):532-9.


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