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Items: 1 to 50 of 74

1.

Polysaccharides-based multiparticulated interpolyelectrolyte complexes for controlled benznidazole release.

García MC, Manzo RH, Jimenez-Kairuz A.

Int J Pharm. 2018 Jul 10;545(1-2):366-377. doi: 10.1016/j.ijpharm.2018.05.017. Epub 2018 May 7.

PMID:
29747000
2.

Multi-kinetic release of benznidazole-loaded multiparticulate drug delivery systems based on polymethacrylate interpolyelectrolyte complexes.

García MC, Martinelli M, Ponce NE, Sanmarco LM, Aoki MP, Manzo RH, Jimenez-Kairuz AF.

Eur J Pharm Sci. 2018 Jul 30;120:107-122. doi: 10.1016/j.ejps.2018.04.034. Epub 2018 Apr 27.

PMID:
29705213
3.

Ciprofloxacin-lidocaine-based hydrogel: development, characterization, and in vivo evaluation in a second-degree burn model.

Sanchez MF, Breda SA, Soria EA, Tártara LI, Manzo RH, Olivera ME.

Drug Deliv Transl Res. 2018 Oct;8(5):1000-1013. doi: 10.1007/s13346-018-0523-7.

PMID:
29654411
4.

Urinary excretion of ciprofloxacin after administration of extended release tablets in healthy volunteers. Swellable drug-polyelectrolyte matrix versus bilayer tablets.

Guzmán ML, Romañuk CB, Sanchez MF, Luciani Giacobbe LC, Alarcón-Ramirez LP, Battistini FD, Alovero FL, Jimenez-Kairuz AF, Manzo RH, Olivera ME.

Drug Deliv Transl Res. 2018 Feb;8(1):123-131. doi: 10.1007/s13346-017-0442-z.

PMID:
29159694
5.

Bioadhesive and biocompatible films as wound dressing materials based on a novel dendronized chitosan loaded with ciprofloxacin.

García MC, Aldana AA, Tártara LI, Alovero F, Strumia MC, Manzo RH, Martinelli M, Jimenez-Kairuz AF.

Carbohydr Polym. 2017 Nov 1;175:75-86. doi: 10.1016/j.carbpol.2017.07.053. Epub 2017 Jul 22.

PMID:
28917926
6.

Application of 1-Dimensional and 2-Dimensional Solid-State Nuclear Magnetic Resonance Spectroscopy to the Characterization of Morphine, Morphine Hydrochloride, and Their Hydrates.

Romañuk CB, Garro-Linck Y, Alves de Santana MS, Manzo RH, Ayala AP, Monti GA, Chattah AK, Olivera ME.

J Pharm Sci. 2017 Oct;106(10):3033-3040. doi: 10.1016/j.xphs.2017.05.021. Epub 2017 May 24.

PMID:
28551429
7.

The role of hyaluronan as a drug carrier to enhance the bioavailability of extended release ophthalmic formulations. Hyaluronan-timolol ionic complexes as a model case.

Battistini FD, Tártara LI, Boiero C, Guzmán ML, Luciani-Giaccobbe LC, Palma SD, Allemandi DA, Manzo RH, Olivera ME.

Eur J Pharm Sci. 2017 Jul 15;105:188-194. doi: 10.1016/j.ejps.2017.05.020. Epub 2017 May 12.

PMID:
28506871
8.
9.

Very fast dissolving acid carboxymethylcellulose-rifampicin matrix: Development and solid-state characterization.

Luciani-Giacobbe LC, Ramírez-Rigo MV, Garro-Linck Y, Monti GA, Manzo RH, Olivera ME.

Eur J Pharm Sci. 2017 Jan 1;96:398-410. doi: 10.1016/j.ejps.2016.10.013. Epub 2016 Oct 6.

PMID:
27721041
10.

A novel gel based on an ionic complex from a dendronized polymer and ciprofloxacin: Evaluation of its use for controlled topical drug release.

García MC, Cuggino JC, Rosset CI, Páez PL, Strumia MC, Manzo RH, Alovero FL, Alvarez Igarzabal CI, Jimenez-Kairuz AF.

Mater Sci Eng C Mater Biol Appl. 2016 Dec 1;69:236-46. doi: 10.1016/j.msec.2016.06.071. Epub 2016 Jun 23.

PMID:
27612709
11.

Reduced food interaction and enhanced gastrointestinal tolerability of a new system based on risedronate complexed with Eudragit E100: Mechanistic approaches from in vitro and in vivo studies.

Guzman ML, Soria EA, Laino C, Manzo RH, Olivera ME.

Eur J Pharm Biopharm. 2016 Oct;107:263-72. doi: 10.1016/j.ejpb.2016.07.012. Epub 2016 Jul 12.

PMID:
27418392
12.

Clomipramine and Benznidazole Act Synergistically and Ameliorate the Outcome of Experimental Chagas Disease.

García MC, Ponce NE, Sanmarco LM, Manzo RH, Jimenez-Kairuz AF, Aoki MP.

Antimicrob Agents Chemother. 2016 May 23;60(6):3700-8. doi: 10.1128/AAC.00404-16. Print 2016 Jun.

13.

Analgesia enhancement and prevention of tolerance to morphine: beneficial effects of combined therapy with omega-3 fatty acids.

Escudero GE, Romañuk CB, Toledo ME, Olivera ME, Manzo RH, Laino CH.

J Pharm Pharmacol. 2015 Sep;67(9):1251-62. doi: 10.1111/jphp.12416. Epub 2015 May 25.

PMID:
26011306
14.

Extemporaneous benznidazole oral suspension prepared from commercially available tablets for treatment of Chagas disease in paediatric patients.

García MC, Manzo RH, Jimenez-Kairuz AF.

Trop Med Int Health. 2015 Jul;20(7):864-70. doi: 10.1111/tmi.12508. Epub 2015 Apr 6.

15.

Ocular delivery of flurbiprofen based on Eudragit(®) E-flurbiprofen complex dispersed in aqueous solution: preparation, characterization, in vitro corneal penetration, and ocular irritation.

Quinteros DA, Tártara LI, Palma SD, Manzo RH, Allemandi DA.

J Pharm Sci. 2014 Dec;103(12):3859-3868. doi: 10.1002/jps.24153. Epub 2014 Oct 7.

PMID:
25294798
16.

Hyaluronan as drug carrier. The in vitro efficacy and selectivity of Hyaluronan-Doxorubicin complexes to affect the viability of overexpressing CD44 receptor cells.

Battistini FD, Flores-Martin J, Olivera ME, Genti-Raimondi S, Manzo RH.

Eur J Pharm Sci. 2014 Dec 18;65:122-9. doi: 10.1016/j.ejps.2014.09.008. Epub 2014 Sep 19.

PMID:
25242358
17.

Formulation and quality control of semi-solid containing harmless bacteria by-products: chronic wounds pro-healing activity.

Sesto Cabral ME, Ramos AN, Macedo AJ, Trentin DS, Treter J, Manzo RH, Valdez JC.

Pharm Dev Technol. 2015 Dec;20(8):911-918. doi: 10.3109/10837450.2014.938858. Epub 2014 Jul 8.

PMID:
25004009
18.

Enhanced intestinal permeability and oral bioavailability of enalapril maleate upon complexation with the cationic polymethacrylate Eudragit E100.

Ramírez-Rigo MV, Olivera ME, Rubio M, Manzo RH.

Eur J Pharm Sci. 2014 May 13;55:1-11. doi: 10.1016/j.ejps.2014.01.001. Epub 2014 Jan 20.

PMID:
24456933
19.

Equilibrium and release properties of hyaluronic acid-drug complexes.

Battistini FD, Olivera ME, Manzo RH.

Eur J Pharm Sci. 2013 Jul 16;49(4):588-94. doi: 10.1016/j.ejps.2013.04.023. Epub 2013 May 6.

PMID:
23659801
20.

Systemic exposure, tissue distribution, and disease evolution of a high solubility ciprofloxacin-aluminum complex in a murine model of septicemia induced by salmonella enterica serotype Enteritidis.

Breda SA, Guzmán ML, Confalonieri A, González C, Sparo M, Manzo RH, Bruni SS, Olivera ME.

Mol Pharm. 2013 Feb 4;10(2):598-605. doi: 10.1021/mp300356a. Epub 2013 Jan 11.

PMID:
23273286
21.

Equilibrium and release properties of aqueous dispersions of non-steroidal anti-inflammatory drugs complexed with polyelectrolyte eudragit e 100.

Quinteros DA, Allemandi DA, Manzo RH.

Sci Pharm. 2012 Apr-Jun;80(2):487-96. doi: 10.3797/scipharm.1107-17. Epub 2012 Apr 30.

22.

Eudragit E100 as a drug carrier: the remarkable affinity of phosphate ester for dimethylamine.

Guzmán ML, Manzo RH, Olivera ME.

Mol Pharm. 2012 Sep 4;9(9):2424-33. doi: 10.1021/mp300282f. Epub 2012 Aug 1.

PMID:
22808998
23.

Eudragit E100® potentiates the bactericidal action of ofloxacin against fluoroquinolone-resistant Pseudomonas aeruginosa.

Romero VL, Pons P, Bocco JL, Manzo RH, Alovero FL.

FEMS Microbiol Lett. 2012 Sep;334(2):102-10. doi: 10.1111/j.1574-6968.2012.02626.x. Epub 2012 Jul 24.

24.

SAR analysis of new dual targeting fluoroquinolones. Implications of the benzenesulfonyl group.

Nieto MJ, Pierini AB, Singh N, McCurdy CR, Manzo RH, Mazzieri MR.

Med Chem. 2012 May;8(3):349-60.

PMID:
22530906
25.

Studies of pilocarpine:carbomer intermolecular interactions.

Zoppi A, Linck YG, Monti GA, Genovese DB, Jimenez Kairuz AF, Manzo RH, Longhi MR.

Int J Pharm. 2012 May 10;427(2):252-9. doi: 10.1016/j.ijpharm.2012.02.005. Epub 2012 Feb 13.

PMID:
22349054
26.

Interaction between Eudragit® E100 and anionic drugs: addition of anionic polyelectrolytes and their influence on drug release performance.

Quinteros DA, Manzo RH, Allemandi DA.

J Pharm Sci. 2011 Nov;100(11):4664-73. doi: 10.1002/jps.22651. Epub 2011 Jun 6.

PMID:
21647887
27.

Multinuclear solid state NMR investigation of two polymorphic forms of ciprofloxacin-saccharinate.

Garro Linck Y, Chattah AK, Graf R, Romañuk CB, Olivera ME, Manzo RH, Monti GA, Spiess HW.

Phys Chem Chem Phys. 2011 Apr 14;13(14):6590-6. doi: 10.1039/c0cp02919j. Epub 2011 Mar 7.

PMID:
21384011
28.
29.

Biowaiver monographs for immediate release solid oral dosage forms: ciprofloxacin hydrochloride.

Olivera ME, Manzo RH, Junginger HE, Midha KK, Shah VP, Stavchansky S, Dressman JB, Barends DM.

J Pharm Sci. 2011 Jan;100(1):22-33. doi: 10.1002/jps.22259. Review.

PMID:
20602455
30.

Design of a colonic delivery system based on cationic polymethacrylate (Eudragit E100)-mesalamine complexes.

Quinteros DA, Manzo RH, Allemandi DA.

Drug Deliv. 2010 May;17(4):208-13. doi: 10.3109/10717541003667806.

PMID:
20230248
31.

Crystallographic, thermal and spectroscopic characterization of a ciprofloxacin saccharinate polymorph.

Romañuk CB, Garro Linck Y, Chattah AK, Monti GA, Cuffini SL, Garland MT, Baggio R, Manzo RH, Olivera ME.

Int J Pharm. 2010 May 31;391(1-2):197-202. doi: 10.1016/j.ijpharm.2010.03.007. Epub 2010 Mar 7.

PMID:
20214961
32.

Colloidal properties of amiodarone in water at low concentration.

Benedini L, Messina PV, Manzo RH, Allemandi DA, Palma SD, Schulz EP, Frechero MA, Schulz PC.

J Colloid Interface Sci. 2010 Feb 15;342(2):407-14. doi: 10.1016/j.jcis.2009.10.071. Epub 2009 Oct 30.

PMID:
19954788
33.

Swellable drug-polyelectrolyte matrices of drug-carboxymethylcellulose complexes. Characterization and delivery properties.

Rigo MV, Allemandi DA, Manzo RH.

Drug Deliv. 2009 Feb;16(2):108-15. doi: 10.1080/10717540802605848 .

PMID:
19267302
34.

Characterization of the solubility and solid-state properties of saccharin salts of fluoroquinolones.

Romañuk CB, Manzo RH, Linck YG, Chattah AK, Monti GA, Olivera ME.

J Pharm Sci. 2009 Oct;98(10):3788-801. doi: 10.1002/jps.21688.

PMID:
19226631
35.

Solubility behavior and biopharmaceutical classification of novel high-solubility ciprofloxacin and norfloxacin pharmaceutical derivatives.

Breda SA, Jimenez-Kairuz AF, Manzo RH, Olivera ME.

Int J Pharm. 2009 Apr 17;371(1-2):106-13. doi: 10.1016/j.ijpharm.2008.12.026. Epub 2008 Dec 27.

PMID:
19150493
36.

Azithromycin loaded on hydrogels of carbomer: chemical stability and delivery properties.

Esteban SL, Manzo RH, Alovero FL.

Int J Pharm. 2009 Jan 21;366(1-2):53-7. doi: 10.1016/j.ijpharm.2008.08.043. Epub 2008 Sep 7.

PMID:
18822364
37.

Novel mucoadhesive extended release tablets for treatment of oral candidosis: "in vivo" evaluation of the biopharmaceutical performance.

Llabot JM, Manzo RH, Allemandi DA.

J Pharm Sci. 2009 May;98(5):1871-6. doi: 10.1002/jps.21513.

PMID:
18803261
38.

A ciprofloxacin extended release tablet based on swellable drug polyelectrolyte matrices.

Bermúdez JM, Jimenez-Kairuz AF, Olivera ME, Allemandi DA, Manzo RH.

AAPS PharmSciTech. 2008;9(3):924-30. doi: 10.1208/s12249-008-9098-9. Epub 2008 Aug 7.

39.

Interaction between a cationic polymethacrylate (Eudragit E100) and anionic drugs.

Quinteros DA, Rigo VR, Kairuz AF, Olivera ME, Manzo RH, Allemandi DA.

Eur J Pharm Sci. 2008 Jan;33(1):72-9. Epub 2007 Oct 23.

PMID:
18060747
40.

NMR and IR characterization of the aluminium complexes of norfloxacin and ciprofloxacin fluoroquinolones.

Chattah AK, Linck YG, Monti GA, Levstein PR, Breda SA, Manzo RH, Olivera ME.

Magn Reson Chem. 2007 Oct;45(10):850-9.

PMID:
17729228
41.

HPLC method for the determination of nystatin in saliva for application in clinical studies.

Llabot JM, Allemandi DA, Manzo RH, Longhi MR.

J Pharm Biomed Anal. 2007 Nov 5;45(3):526-30. Epub 2007 Jun 16.

PMID:
17658236
42.

Design of novel antifungal mucoadhesive films. Part II. Formulation and in vitro biopharmaceutical evaluation.

Llabot JM, Palma SD, Manzo RH, Allemandi DA.

Int J Pharm. 2007 May 24;336(2):263-8. Epub 2006 Dec 6.

PMID:
17223291
43.

Design of novel antifungal mucoadhesive films Part I. Pre-formulation studies.

Llabot JM, Palma SD, Manzo RH, Allemandi DA.

Int J Pharm. 2007 Feb 7;330(1-2):54-60. Epub 2006 Sep 1.

PMID:
17071026
44.

Potential use of ascorbic acid-based surfactants as skin penetration enhancers.

Palma SD, Maletto B, Lo Nostro P, Manzo RH, Pistoresi-Palencia MC, Allemandi DA.

Drug Dev Ind Pharm. 2006 Aug;32(7):821-7.

PMID:
16908419
45.

Swellable drug-polyelectrolyte matrices (SDPM) of alginic acid characterization and delivery properties.

Rigo MV, Allemandi DA, Manzo RH.

Int J Pharm. 2006 Sep 28;322(1-2):36-43. Epub 2006 May 17.

PMID:
16806753
46.

Biowaiver monographs for immediate release solid oral dosage forms: amitriptyline hydrochloride.

Manzo RH, Olivera ME, Amidon GL, Shah VP, Dressman JB, Barends DM.

J Pharm Sci. 2006 May;95(5):966-73.

47.

A linear free energy relationship treatment of the affinity between carboxymethylcellulose and basic drugs.

Ramírez Rigo MV, Allemandi DA, Manzo RH.

Mol Pharm. 2004 Sep-Oct;1(5):383-6.

PMID:
16026009
48.

Benzenesulfonamide analogs of fluoroquinolones. Antibacterial activity and QSAR studies.

Nieto MJ, Alovero FL, Manzo RH, Mazzieri MR.

Eur J Med Chem. 2005 Apr;40(4):361-9.

PMID:
15804535
49.

Swellable drug-polyelectrolyte matrices (SDPM). Characterization and delivery properties.

Jimenez-Kairuz AF, Llabot JM, Allemandi DA, Manzo RH.

Int J Pharm. 2005 Jan 6;288(1):87-99.

PMID:
15607261
50.

Ototopical ciprofloxacin in a glycerin vehicle for the treatment of acute external otitis.

Olivera ME, Bistoni A, Anun HE, Salinas A, Manzo RH.

Ear Nose Throat J. 2004 Sep;83(9):625-6, 628, 630 passim.

PMID:
15529649

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