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Items: 1 to 50 of 219

1.

Infusions of Large Synthetic HDL Containing Trimeric apoA-I Stabilize Atherosclerotic Plaques in Hypercholesterolemic Rabbits.

Parolini C, Adorni MP, Busnelli M, Manzini S, Cipollari E, Favari E, Lorenzon P, Ganzetti GS, Fingerle J, Bernini F, Chiesa G.

Can J Cardiol. 2019 May 30. pii: S0828-282X(19)30379-4. doi: 10.1016/j.cjca.2019.05.033. [Epub ahead of print]

PMID:
31495683
2.

MEN1309/OBT076, a First-In-Class Antibody-Drug Conjugate Targeting CD205 in Solid Tumors.

Merlino G, Fiascarelli A, Bigioni M, Bressan A, Carrisi C, Bellarosa D, Salerno M, Bugianesi R, Manno R, Bernadó Morales C, Arribas J, Dusek RL, Ackroyd JE, Pham PH, Awdew R, Aud D, Trang M, Lynch CM, Terrett J, Wilson KE, Rohlff C, Manzini S, Pellacani A, Binaschi M.

Mol Cancer Ther. 2019 Sep;18(9):1533-1543. doi: 10.1158/1535-7163.MCT-18-0624. Epub 2019 Jun 21.

PMID:
31227646
3.

Topiramate protects apoE-deficient mice from kidney damage without affecting plasma lipids.

Manzini S, Busnelli M, Parolini C, Minoli L, Ossoli A, Brambilla E, Simonelli S, Lekka E, Persidis A, Scanziani E, Chiesa G.

Pharmacol Res. 2019 Mar;141:189-200. doi: 10.1016/j.phrs.2018.12.022. Epub 2018 Dec 26.

PMID:
30593851
4.

Effects of Vegetable Proteins on Hypercholesterolemia and Gut Microbiota Modulation.

Busnelli M, Manzini S, Sirtori CR, Chiesa G, Parolini C.

Nutrients. 2018 Sep 6;10(9). pii: E1249. doi: 10.3390/nu10091249. Review.

5.

Lipid phosphate phosphatase 3 in vascular pathophysiology.

Busnelli M, Manzini S, Parolini C, Escalante-Alcalde D, Chiesa G.

Atherosclerosis. 2018 Apr;271:156-165. doi: 10.1016/j.atherosclerosis.2018.02.025. Epub 2018 Mar 2. Review.

PMID:
29518748
6.

Effect of Dietary Components from Antarctic Krill on Atherosclerosis in apoE-Deficient Mice.

Parolini C, Bjorndal B, Busnelli M, Manzini S, Ganzetti GS, Dellera F, Ramsvik M, Bruheim I, Berge RK, Chiesa G.

Mol Nutr Food Res. 2017 Dec;61(12). doi: 10.1002/mnfr.201700098. Epub 2017 Nov 7.

PMID:
28812326
7.

Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE-/- mice.

Busnelli M, Manzini S, Hilvo M, Parolini C, Ganzetti GS, Dellera F, Ekroos K, Jänis M, Escalante-Alcalde D, Sirtori CR, Laaksonen R, Chiesa G.

Sci Rep. 2017 Mar 14;7:44503. doi: 10.1038/srep44503.

8.

Nutraceuticals and Bioactive Components from Fish for Dyslipidemia and Cardiovascular Risk Reduction.

Chiesa G, Busnelli M, Manzini S, Parolini C.

Mar Drugs. 2016 Jun 8;14(6). pii: E113. doi: 10.3390/md14060113. Review.

9.

L-homoarginine administration reduces neointimal hyperplasia in balloon-injured rat carotids.

Dellera F, Ganzetti GS, Froio A, Manzini S, Busnelli M, Meinitzer A, Sirtori CR, Chiesa G, Parolini C.

Thromb Haemost. 2016 Aug 1;116(2):400-2. doi: 10.1160/TH15-10-0831. Epub 2016 Jun 9. No abstract available.

10.

A Comparative View on Easy to Deploy non-Integrating Methods for Patient-Specific iPSC Production.

Manzini S, Viiri LE, Marttila S, Aalto-Setälä K.

Stem Cell Rev Rep. 2015 Dec;11(6):900-8. doi: 10.1007/s12015-015-9619-3.

11.

Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride.

Schotten C, Plaza D, Manzini S, Nolan SP, Ley SV, Browne DL, Lapkin A.

ACS Sustain Chem Eng. 2015 Jul 6;3(7):1453-1459. Epub 2015 May 26.

12.

Beta2-adrenergic activity modulates vascular tone regulation in lecithin:cholesterol acyltransferase knockout mice.

Manzini S, Pinna C, Busnelli M, Cinquanta P, Rigamonti E, Ganzetti GS, Dellera F, Sala A, Calabresi L, Franceschini G, Parolini C, Chiesa G.

Vascul Pharmacol. 2015 Nov;74:114-121. doi: 10.1016/j.vph.2015.08.006. Epub 2015 Aug 5.

13.

High-density lipoprotein deficiency in genetically modified mice deeply affects skin morphology: A structural and ultrastructural study.

Arnaboldi F, Busnelli M, Cornaghi L, Manzini S, Parolini C, Dellera F, Ganzetti GS, Sirtori CR, Donetti E, Chiesa G.

Exp Cell Res. 2015 Oct 15;338(1):105-12. doi: 10.1016/j.yexcr.2015.07.032. Epub 2015 Aug 1.

PMID:
26241937
14.

Investigations on the catalytic carboxylation of olefins with CO2 towards α,β-unsaturated carboxylic acid salts: characterization of intermediates and ligands as well as substrate effects.

Jevtovikj I, Manzini S, Hanauer M, Rominger F, Schaub T.

Dalton Trans. 2015 Jun 28;44(24):11083-94. doi: 10.1039/c5dt01040c. Epub 2015 May 22.

PMID:
25999232
15.

From a decomposition product to an efficient and versatile catalyst: the [Ru(η5-indenyl)(PPh3)2Cl] story.

Manzini S, Fernández-Salas JA, Nolan SP.

Acc Chem Res. 2014 Oct 21;47(10):3089-101. doi: 10.1021/ar500225j. Epub 2014 Sep 29.

16.

Regioselective ruthenium catalysed H-D exchange using D2O as the deuterium source.

Piola L, Fernández-Salas JA, Manzini S, Nolan SP.

Org Biomol Chem. 2014 Nov 21;12(43):8683-8. doi: 10.1039/c4ob01798f.

PMID:
25252806
17.

A cationic ruthenium complex for the dynamic kinetic resolution of secondary alcohols.

Fernández-Salas JA, Manzini S, Nolan SP.

Chemistry. 2014 Oct 6;20(41):13132-5. doi: 10.1002/chem.201404096. Epub 2014 Aug 28.

PMID:
25167839
18.

The use of the sterically demanding IPr* and related ligands in catalysis.

Izquierdo F, Manzini S, Nolan SP.

Chem Commun (Camb). 2014 Dec 11;50(95):14926-37. doi: 10.1039/c4cc05289g.

PMID:
25155373
19.

Key processes in ruthenium-catalysed olefin metathesis.

Nelson DJ, Manzini S, Urbina-Blanco CA, Nolan SP.

Chem Commun (Camb). 2014 Sep 18;50(72):10355-75. doi: 10.1039/c4cc02515f.

PMID:
24931143
20.

Insights into the decomposition of olefin metathesis precatalysts.

Manzini S, Poater A, Nelson DJ, Cavallo L, Slawin AM, Nolan SP.

Angew Chem Int Ed Engl. 2014 Aug 18;53(34):8995-9. doi: 10.1002/anie.201403770. Epub 2014 Jun 2.

PMID:
24891114
21.

A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in ApoE-deficient mice.

Parolini C, Vik R, Busnelli M, Bjørndal B, Holm S, Brattelid T, Manzini S, Ganzetti GS, Dellera F, Halvorsen B, Aukrust P, Sirtori CR, Nordrehaug JE, Skorve J, Berge RK, Chiesa G.

PLoS One. 2014 May 19;9(5):e97598. doi: 10.1371/journal.pone.0097598. eCollection 2014.

22.

Ruthenium catalysed C-H bond borylation.

Fernández-Salas JA, Manzini S, Piola L, Slawin AM, Nolan SP.

Chem Commun (Camb). 2014 Jun 28;50(51):6782-4. doi: 10.1039/c4cc02096k.

PMID:
24835857
23.

Magnetic resonance imaging visualization of vulnerable atherosclerotic plaques at the brachiocephalic artery of apolipoprotein E knockout mice by the blood-pool contrast agent B22956/1.

Parolini C, Busnelli M, Ganzetti GS, Dellera F, Manzini S, Scanziani E, Johnson JL, Sirtori CR, Chiesa G.

Mol Imaging. 2014;13. doi: 10.2310/7290.2014.00012.

PMID:
24825406
24.

From ruthenium olefin metathesis catalyst to (η5-3-phenylindenyl)hydrido complex via alcoholysis.

Manzini S, Nelson DJ, Lebl T, Poater A, Cavallo L, Slawin AM, Nolan SP.

Chem Commun (Camb). 2014 Feb 28;50(17):2205-7. doi: 10.1039/c3cc49481k. Epub 2014 Jan 16.

PMID:
24435451
25.

An immunomodulating fatty acid analogue targeting mitochondria exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in apoe(-/-) mice.

Vik R, Busnelli M, Parolini C, Bjørndal B, Holm S, Bohov P, Halvorsen B, Brattelid T, Manzini S, Ganzetti GS, Dellera F, Nygård OK, Aukrust P, Sirtori CR, Chiesa G, Berge RK.

PLoS One. 2013 Dec 4;8(12):e81963. doi: 10.1371/journal.pone.0081963. eCollection 2013.

26.

Diet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatment.

Busnelli M, Manzini S, Froio A, Vargiolu A, Cerrito MG, Smolenski RT, Giunti M, Cinti A, Zannoni A, Leone BE, Forni M, Bacci ML, Biasi GM, Giovannoni R, Lavitrano M.

PLoS One. 2013 Nov 15;8(11):e80588. doi: 10.1371/journal.pone.0080588. eCollection 2013.

27.

Facile and efficient KOH-catalysed reduction of esters and tertiary amides.

Fernández-Salas JA, Manzini S, Nolan SP.

Chem Commun (Camb). 2013 Oct 28;49(84):9758-60. doi: 10.1039/c3cc45930f.

PMID:
24022085
28.

Efficient ruthenium-catalysed S-S, S-Si and S-B bond forming reactions.

Fernández-Salas JA, Manzini S, Nolan SP.

Chem Commun (Camb). 2013 Jul 4;49(52):5829-31. doi: 10.1039/c3cc43145b. Epub 2013 May 23.

PMID:
23702800
29.

The activation mechanism of Ru-indenylidene complexes in olefin metathesis.

Urbina-Blanco CA, Poater A, Lebl T, Manzini S, Slawin AM, Cavallo L, Nolan SP.

J Am Chem Soc. 2013 May 8;135(18):7073-9. doi: 10.1021/ja402700p. Epub 2013 Apr 25.

PMID:
23617632
30.

Effect of the combinations between pea proteins and soluble fibres on cholesterolaemia and cholesterol metabolism in rats.

Parolini C, Manzini S, Busnelli M, Rigamonti E, Marchesi M, Diani E, Sirtori CR, Chiesa G.

Br J Nutr. 2013 Oct;110(8):1394-401. doi: 10.1017/S0007114513000639. Epub 2013 Mar 5.

PMID:
23458494
31.

How does the addition of steric hindrance to a typical N-heterocyclic carbene ligand affect catalytic activity in olefin metathesis?

Poater A, Falivene L, Urbina-Blanco CA, Manzini S, Nolan SP, Cavallo L.

Dalton Trans. 2013 May 28;42(20):7433-9. doi: 10.1039/c3dt32980a.

PMID:
23455458
32.

Reduced biliary sterol output with no change in total faecal excretion in mice expressing a human apolipoprotein A-I variant.

Parolini C, Caligari S, Gilio D, Manzini S, Busnelli M, Montagnani M, Locatelli M, Diani E, Giavarini F, Caruso D, Roda E, Roda A, Sirtori CR, Chiesa G.

Liver Int. 2012 Oct;32(9):1363-71. doi: 10.1111/j.1478-3231.2012.02855.x. Epub 2012 Jul 29.

PMID:
22845860
33.

Cholesterol-lowering effect of dietary Lupinus angustifolius proteins in adult rats through regulation of genes involved in cholesterol homeostasis.

Parolini C, Rigamonti E, Marchesi M, Busnelli M, Cinquanta P, Manzini S, Sirtori CR, Chiesa G.

Food Chem. 2012 Jun 1;132(3):1475-1479. doi: 10.1016/j.foodchem.2011.12.004. Epub 2011 Dec 11.

PMID:
29243638
34.

From olefin metathesis catalyst to alcohol racemization catalyst in one step.

Manzini S, Urbina-Blanco CA, Poater A, Slawin AM, Cavallo L, Nolan SP.

Angew Chem Int Ed Engl. 2012 Jan 23;51(4):1042-5. doi: 10.1002/anie.201106915. Epub 2011 Dec 12. No abstract available.

PMID:
22161985
35.

Combined antihypertensive and cardioprotective effects of nebivolol and hydrochlorothiazide in spontaneous hypertensive rats.

Sacco G, Evangelista S, Manzini S, Parlani M, Bigioni M.

Future Cardiol. 2011 Nov;7(6):757-63. doi: 10.2217/fca.11.70.

PMID:
22050062
36.

Optimization of a Dynamic Headspace-Thermal Desorption-Gas Chromatography/Mass Spectrometry procedure for the determination of furfurals in vinegars.

Manzini S, Durante C, Baschieri C, Cocchi M, Sighinolfi S, Totaro S, Marchetti A.

Talanta. 2011 Aug 15;85(2):863-9. doi: 10.1016/j.talanta.2011.04.018. Epub 2011 May 31.

PMID:
21726711
37.

Increased plasma levels of extracellular mitochondrial DNA during HIV infection: a new role for mitochondrial damage-associated molecular patterns during inflammation.

Cossarizza A, Pinti M, Nasi M, Gibellini L, Manzini S, Roat E, De Biasi S, Bertoncelli L, Montagna JP, Bisi L, Manzini L, Trenti T, Borghi V, Mussini C.

Mitochondrion. 2011 Sep;11(5):750-5. doi: 10.1016/j.mito.2011.06.005. Epub 2011 Jun 23.

PMID:
21722755
38.

Decreased mitochondrial DNA content in subcutaneous fat from HIV-infected women taking antiretroviral therapy as measured at delivery.

Nasi M, Pinti M, Chiesa E, Fiore S, Manzini S, Del Giovane C, D'Amico R, Palai N, Campatelli C, Sabbatini F, Roccio M, Tibaldi C, Masuelli G, Mussini C, Ferrazzi E, d'Arminio Monforte A, Cossarizza A; Target Study Group.

Antivir Ther. 2011;16(3):365-72. doi: 10.3851/IMP1764.

PMID:
21555819
39.

CD4+ T-cell differentiation, regulatory T cells and gag-specific T lymphocytes are unaffected by CD4-guided treatment interruption and therapy resumption.

Nemes E, Lugli E, Bertoncelli L, Nasi M, Pinti M, Manzini S, Prati F, Manzini L, Del Giovane C, D'Amico R, Cossarizza A, Mussini C.

AIDS. 2011 Jul 31;25(12):1443-53. doi: 10.1097/QAD.0b013e328347b5e2.

PMID:
21505295
40.

Rosuvastatin does not affect human apolipoprotein A-I expression in genetically modified mice: a clue to the disputed effect of statins on HDL.

Marchesi M, Parolini C, Caligari S, Gilio D, Manzini S, Busnelli M, Cinquanta P, Camera M, Brambilla M, Sirtori CR, Chiesa G.

Br J Pharmacol. 2011 Nov;164(5):1460-8. doi: 10.1111/j.1476-5381.2011.01429.x.

41.

Simple synthetic routes to ruthenium-indenylidene olefin metathesis catalysts.

Urbina-Blanco CA, Manzini S, Gomes JP, Doppiu A, Nolan SP.

Chem Commun (Camb). 2011 May 7;47(17):5022-4. doi: 10.1039/c1cc10741k. Epub 2011 Mar 21.

PMID:
21423960
42.

Atomic force microscopy study of DNA conformation in the presence of drugs.

Cassina V, Seruggia D, Beretta GL, Salerno D, Brogioli D, Manzini S, Zunino F, Mantegazza F.

Eur Biophys J. 2011 Jan;40(1):59-68. doi: 10.1007/s00249-010-0627-6. Epub 2010 Sep 30.

PMID:
20882274
43.

In vitro production of multigene transgenic blastocysts via sperm-mediated gene transfer allows rapid screening of constructs to be used in xenotransplantation experiments.

Vargiolu A, Manzini S, de Cecco M, Bacci ML, Forni M, Galeati G, Cerrito MG, Busnelli M, Lavitrano M, Giovannoni R.

Transplant Proc. 2010 Jul-Aug;42(6):2142-5. doi: 10.1016/j.transproceed.2010.05.115.

PMID:
20692428
44.

Predictive value of intracellular HIV-1 DNA levels during CD4-guided treatment interruption in HIV+ patients.

Nasi M, Pinti M, Manzini S, Gibellini L, Manzini L, Bisi L, De Biasi S, Del Giovane C, D'Amico R, Borghi V, Mussini C, Cossarizza A.

AIDS Res Hum Retroviruses. 2010 May;26(5):553-8. doi: 10.1089/aid.2009.0256.

PMID:
20455764
45.

Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infection.

Nemes E, Bertoncelli L, Lugli E, Pinti M, Nasi M, Manzini L, Manzini S, Prati F, Borghi V, Cossarizza A, Mussini C.

AIDS. 2010 Apr 24;24(7):947-57. doi: 10.1097/QAD.0b013e328337b144.

PMID:
20179574
46.

Influence of tachykinin NK2 receptors on intestinal sensitivity and motility in newborn rats.

Tramontana M, Evangelista S, Giuliani S, Manzini S, Robelet S, Girod V, Maggi CA.

Neuropeptides. 2010 Jun;44(3):269-72. doi: 10.1016/j.npep.2010.01.002.

PMID:
20137809
47.

Antitumor activity of delimotecan against human metastatic melanoma: pharmacokinetics and molecular determinants.

Bigioni M, Parlani M, Bressan A, Bellarosa D, Rivoltini L, Animati F, Crea A, Bugianesi R, Maggi CA, Manzini S, Binaschi M.

Int J Cancer. 2009 Nov 15;125(10):2456-64. doi: 10.1002/ijc.24661.

48.

ACE inhibition and protection from doxorubicin-induced cardiotoxicity in the rat.

Sacco G, Mario B, Lopez G, Evangelista S, Manzini S, Maggi CA.

Vascul Pharmacol. 2009 May-Jun;50(5-6):166-70. doi: 10.1016/j.vph.2009.01.001.

PMID:
19344651
49.

Changes in the chemical composition of reduced cooked musts during the heating process.

Cocchi M, Consonni R, Durante C, Grandi M, Manzini S, Marchetti A, Sighinolfi S.

J Agric Food Chem. 2008 Aug 13;56(15):6397-407. doi: 10.1021/jf800353a. Epub 2008 Jul 4.

PMID:
18598041
50.

Sabarubicin (MEN10755)-induced apoptosis is independent from mtDNA in A2780 human ovarian tumor cells.

Bressan A, Nardelli F, Bellarosa D, Bigioni M, Curcurù G, Curatella B, Crea A, Maggi CA, Manzini S, Binaschi M.

Anticancer Res. 2007 Nov-Dec;27(6B):4039-46.

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