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Items: 1 to 50 of 111

1.

Transitions in cell potency during early mouse development are driven by Notch.

Menchero S, Rollan I, Lopez-Izquierdo A, Andreu MJ, Sainz de Aja J, Kang M, Adan J, Benedito R, Rayon T, Hadjantonakis AK, Manzanares M.

Elife. 2019 Apr 8;8. pii: e42930. doi: 10.7554/eLife.42930.

2.

The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.

Sainz de Aja J, Menchero S, Rollan I, Barral A, Tiana M, Jawaid W, Cossio I, Alvarez A, Carreño-Tarragona G, Badia-Careaga C, Nichols J, Göttgens B, Isern J, Manzanares M.

EMBO J. 2019 Apr 1;38(7). pii: e99122. doi: 10.15252/embj.201899122. Epub 2019 Feb 27.

3.

Vascularized Periosteal Flaps Accelerate Osteointegration and Revascularization of Allografts in Rats.

Gallardo-Calero I, Barrera-Ochoa S, Manzanares MC, Sallent A, Vicente M, López-Fernández A, De Albert M, Aguirre M, Soldado F, Vélez R.

Clin Orthop Relat Res. 2019 Apr;477(4):741-755. doi: 10.1097/CORR.0000000000000400.

PMID:
30810538
4.

Impact of Biomimicry in the Design of Osteoinductive Bone Substitutes: Nanoscale Matters.

Barba A, Diez-Escudero A, Espanol M, Bonany M, Sadowska JM, Guillem-Marti J, Öhman-Mägi C, Persson C, Manzanares MC, Franch J, Ginebra MP.

ACS Appl Mater Interfaces. 2019 Mar 6;11(9):8818-8830. doi: 10.1021/acsami.8b20749. Epub 2019 Feb 21.

PMID:
30740968
5.

The Incidence of Dental Needs During Isolated Missions Compared to Non-isolated Missions: A Systematic Review and Implications for Future Prevention Strategies.

Lloro V, Lozano-de Luaces V, Lloro I, Manzanares MC.

Mil Med. 2018 Dec 7. doi: 10.1093/milmed/usy364. [Epub ahead of print]

PMID:
30535397
6.

MUCOSAL Anti-Infections Vaccines: Beyond Conventional Vaccines.

Sánchez Ramón S, Manzanares M, Candelas G.

Reumatol Clin. 2018 Dec 6. pii: S1699-258X(18)30241-9. doi: 10.1016/j.reuma.2018.10.012. [Epub ahead of print] Review. English, Spanish.

7.

Osteogenesis by foamed and 3D-printed nanostructured calcium phosphate scaffolds: Effect of pore architecture.

Barba A, Maazouz Y, Diez-Escudero A, Rappe K, Espanol M, Montufar EB, Öhman-Mägi C, Persson C, Fontecha P, Manzanares MC, Franch J, Ginebra MP.

Acta Biomater. 2018 Oct 1;79:135-147. doi: 10.1016/j.actbio.2018.09.003. Epub 2018 Sep 6.

PMID:
30195084
8.

The anterior tibiofibular ligament has a constant distal fascicle that contacts the anterolateral part of the talus.

Dalmau-Pastor M, Malagelada F, Kerkhoffs GMMJ, Karlsson J, Manzanares MC, Vega J.

Knee Surg Sports Traumatol Arthrosc. 2018 Aug 29. doi: 10.1007/s00167-018-5123-z. [Epub ahead of print]

PMID:
30159737
9.

Autologous stem cell transplantation may be curative for patients with follicular lymphoma with early therapy failure who reach complete response after rescue treatment.

Jiménez-Ubieto A, Grande C, Caballero D, Yáñez L, Novelli S, Hernández-Garcia MT, Manzanares M, Arranz R, Ferreiro JJ, Bobillo S, Mercadal S, Galeo A, Jiménez JL, Moraleda JM, Vallejo C, Albo C, Pérez E, Marrero C, Magnano L, Palomera L, Jarque I, Martínez-Sánchez P, Martín A, Coria E, López-Guillermo A, Salar A, Lahuerta JJ; GELTAMO (Grupo Español de Linfomas y Trasplantes de Médula Ósea) Cooperative Study Group.

Hematol Oncol. 2018 Dec;36(5):765-772. doi: 10.1002/hon.2553. Epub 2018 Sep 12. No abstract available.

PMID:
30129233
10.

Our First Choice: Cellular and Genetic Underpinnings of Trophectoderm Identity and Differentiation in the Mammalian Embryo.

Menchero S, Sainz de Aja J, Manzanares M.

Curr Top Dev Biol. 2018;128:59-80. doi: 10.1016/bs.ctdb.2017.10.009. Review.

PMID:
29477171
11.

Overexpression of periostin and distinct mesothelin forms predict malignant progression in a rat cholangiocarcinoma model.

Manzanares MÁ, Campbell DJW, Maldonado GT, Sirica AE.

Hepatol Commun. 2017 Dec 18;2(2):155-172. doi: 10.1002/hep4.1131. eCollection 2018 Feb.

12.

Osteoinduction by Foamed and 3D-Printed Calcium Phosphate Scaffolds: Effect of Nanostructure and Pore Architecture.

Barba A, Diez-Escudero A, Maazouz Y, Rappe K, Espanol M, Montufar EB, Bonany M, Sadowska JM, Guillem-Marti J, Öhman-Mägi C, Persson C, Manzanares MC, Franch J, Ginebra MP.

ACS Appl Mater Interfaces. 2017 Dec 6;9(48):41722-41736. doi: 10.1021/acsami.7b14175. Epub 2017 Nov 20.

PMID:
29116737
13.

Progression-free survival at 2 years post-autologous transplant: a surrogate end point for overall survival in follicular lymphoma.

Jiménez-Ubieto A, Grande C, Caballero D, Yáñez L, Novelli S, Hernández MT, Manzanares M, Arranz R, Ferreiro JJ, Bobillo S, Mercadal S, Galego A, Jiménez JL, Moraleda JM, Vallejo C, Albo C, Pérez E, Marrero C, Magnano L, Palomera L, Jarque I, Coria E, Rodriguez A, Martín A, López-Guillermo A, Salar A, Lahuerta JJ; GELTAMO (Grupo Español de Linfomas y Trasplantes de Médula Ósea) cooperative study group.

Cancer Med. 2017 Dec;6(12):2766-2774. doi: 10.1002/cam4.1217. Epub 2017 Oct 26.

14.

An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms.

Tapial J, Ha KCH, Sterne-Weiler T, Gohr A, Braunschweig U, Hermoso-Pulido A, Quesnel-Vallières M, Permanyer J, Sodaei R, Marquez Y, Cozzuto L, Wang X, Gómez-Velázquez M, Rayon T, Manzanares M, Ponomarenko J, Blencowe BJ, Irimia M.

Genome Res. 2017 Oct;27(10):1759-1768. doi: 10.1101/gr.220962.117. Epub 2017 Aug 30.

15.

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.

Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, Nieto-Arellano R, Tena JJ, Rollan I, Alvarez A, Torroja C, Caceres EF, Roy AR, Galjart N, Delgado-Olguin P, Sanchez-Cabo F, Enriquez JA, Gomez-Skarmeta JL, Manzanares M.

PLoS Genet. 2017 Aug 28;13(8):e1006985. doi: 10.1371/journal.pgen.1006985. eCollection 2017 Aug.

16.

X-shaped inferior extensor retinaculum and its doubtful use in the Bröstrom-Gould procedure.

Dalmau-Pastor M, Malagelada F, Kerkhoffs GMMJ, Manzanares MC, Vega J.

Knee Surg Sports Traumatol Arthrosc. 2018 Jul;26(7):2171-2176. doi: 10.1007/s00167-017-4647-y. Epub 2017 Jul 14.

PMID:
28710509
17.

External Cervical Resorption: A New Oral Manifestation of Systemic Sclerosis.

Arroyo-Bote S, Bucchi C, Manzanares MC.

J Endod. 2017 Oct;43(10):1740-1743. doi: 10.1016/j.joen.2017.03.040. Epub 2017 Jun 9.

PMID:
28606671
18.

Autologous Stem Cell Transplantation for Follicular Lymphoma: Favorable Long-Term Survival Irrespective of Pretransplantation Rituximab Exposure.

Jiménez-Ubieto A, Grande C, Caballero D, Yáñez L, Novelli S, Hernández-Garcia MT, Manzanares M, Arranz R, Ferreiro JJ, Bobillo S, Mercadal S, Galeo A, López Jiménez J, Moraleda JM, Vallejo C, Albo C, Pérez E, Marrero C, Magnano L, Palomera L, Jarque I, Martínez-Sánchez P, Martín A, Coria E, López-Guillermo A, Salar A, Lahuerta JJ.

Biol Blood Marrow Transplant. 2017 Oct;23(10):1631-1640. doi: 10.1016/j.bbmt.2017.05.021. Epub 2017 May 19.

19.

Transforming Growth Factors α and β Are Essential for Modeling Cholangiocarcinoma Desmoplasia and Progression in a Three-Dimensional Organotypic Culture Model.

Manzanares MÁ, Usui A, Campbell DJ, Dumur CI, Maldonado GT, Fausther M, Dranoff JA, Sirica AE.

Am J Pathol. 2017 May;187(5):1068-1092. doi: 10.1016/j.ajpath.2017.01.013. Epub 2017 Mar 15.

20.

Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the mammary gland.

Manzanares MÁ, de Miguel C, Ruiz de Villa MC, Santella RM, Escrich E, Solanas M.

J Nutr Biochem. 2017 May;43:68-77. doi: 10.1016/j.jnutbio.2017.01.016. Epub 2017 Feb 10.

PMID:
28264783
21.

Signaling pathways in mammalian preimplantation development: Linking cellular phenotypes to lineage decisions.

Menchero S, Rayon T, Andreu MJ, Manzanares M.

Dev Dyn. 2017 Apr;246(4):245-261. doi: 10.1002/dvdy.24471. Epub 2016 Dec 29. Review.

22.

Distinct mechanisms regulate Cdx2 expression in the blastocyst and in trophoblast stem cells.

Rayon T, Menchero S, Rollán I, Ors I, Helness A, Crespo M, Nieto A, Azuara V, Rossant J, Manzanares M.

Sci Rep. 2016 Jun 3;6:27139. doi: 10.1038/srep27139.

23.

Anatomy of the ankle ligaments: a pictorial essay.

Golanó P, Vega J, de Leeuw PA, Malagelada F, Manzanares MC, Götzens V, van Dijk CN.

Knee Surg Sports Traumatol Arthrosc. 2016 Apr;24(4):944-56. doi: 10.1007/s00167-016-4059-4. Epub 2016 Apr 1.

PMID:
27052302
24.

Active DNA demethylation at enhancers during the vertebrate phylotypic period.

Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R.

Nat Genet. 2016 Apr;48(4):417-26. doi: 10.1038/ng.3522. Epub 2016 Feb 29.

25.

Claudin-16 Deficiency Impairs Tight Junction Function in Ameloblasts, Leading to Abnormal Enamel Formation.

Bardet C, Courson F, Wu Y, Khaddam M, Salmon B, Ribes S, Thumfart J, Yamaguti PM, Rochefort GY, Figueres ML, Breiderhoff T, Garcia-Castaño A, Vallée B, Le Denmat D, Baroukh B, Guilbert T, Schmitt A, Massé JM, Bazin D, Lorenz G, Morawietz M, Hou J, Carvalho-Lobato P, Manzanares MC, Fricain JC, Talmud D, Demontis R, Neves F, Zenaty D, Berdal A, Kiesow A, Petzold M, Menashi S, Linglart A, Acevedo AC, Vargas-Poussou R, Müller D, Houillier P, Chaussain C.

J Bone Miner Res. 2016 Mar;31(3):498-513. doi: 10.1002/jbmr.2726. Epub 2015 Oct 20.

26.

In Vivo Osteogenic Potential of Biomimetic Hydroxyapatite/Collagen Microspheres: Comparison with Injectable Cement Pastes.

Cuzmar E, Perez RA, Manzanares MC, Ginebra MP, Franch J.

PLoS One. 2015 Jul 1;10(7):e0131188. doi: 10.1371/journal.pone.0131188. eCollection 2015.

27.

Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP.

Aguirre LA, Alonso ME, Badía-Careaga C, Rollán I, Arias C, Fernández-Miñán A, López-Jiménez E, Aránega A, Gómez-Skarmeta JL, Franco D, Manzanares M.

BMC Biol. 2015 Apr 17;13:26. doi: 10.1186/s12915-015-0138-0.

28.

Surface modification of TiO₂ nanocrystals by WO(x) coating or wrapping: solvothermal synthesis and enhanced surface chemistry.

Epifani M, Díaz R, Force C, Comini E, Manzanares M, Andreu T, Genç A, Arbiol J, Siciliano P, Faglia G, Morante JR.

ACS Appl Mater Interfaces. 2015 Apr 1;7(12):6898-908. doi: 10.1021/acsami.5b00632. Epub 2015 Mar 23.

PMID:
25775118
29.

MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM.

Pernaute B, Spruce T, Smith KM, Sánchez-Nieto JM, Manzanares M, Cobb B, Rodríguez TA.

Genes Dev. 2014 Sep 1;28(17):1873-8. doi: 10.1101/gad.245621.114.

30.

Ontogeny of the major xenobiotic-metabolizing enzymes expression and the dietary lipids modulatory effect in the rat dimethylbenz(a)anthracene-induced breast cancer model.

Manzanares MÁ, Solanas M, Moral R, Escrich R, Vela E, Escrich E.

J Biochem Mol Toxicol. 2014 Dec;28(12):539-48. doi: 10.1002/jbt.21596. Epub 2014 Aug 28.

PMID:
25164943
31.

Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst.

Rayon T, Menchero S, Nieto A, Xenopoulos P, Crespo M, Cockburn K, Cañon S, Sasaki H, Hadjantonakis AK, de la Pompa JL, Rossant J, Manzanares M.

Dev Cell. 2014 Aug 25;30(4):410-22. doi: 10.1016/j.devcel.2014.06.019. Epub 2014 Aug 7.

32.

Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia.

Piazzolla D, Palla AR, Pantoja C, Cañamero M, de Castro IP, Ortega S, Gómez-López G, Dominguez O, Megías D, Roncador G, Luque-Garcia JL, Fernandez-Tresguerres B, Fernandez AF, Fraga MF, Rodriguez-Justo M, Manzanares M, Sánchez-Carbayo M, García-Pedrero JM, Rodrigo JP, Malumbres M, Serrano M.

Nat Commun. 2014 Jun 30;5:4226. doi: 10.1038/ncomms5226.

PMID:
24979572
33.

A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system.

van Weerd JH, Badi I, van den Boogaard M, Stefanovic S, van de Werken HJ, Gomez-Velazquez M, Badia-Careaga C, Manzanares M, de Laat W, Barnett P, Christoffels VM.

Circ Res. 2014 Aug 1;115(4):432-41. doi: 10.1161/CIRCRESAHA.115.303591. Epub 2014 Jun 24.

PMID:
24963028
34.

Dietary extra-virgin olive oil and corn oil differentially modulate the mRNA expression of xenobiotic-metabolizing enzymes in the liver and in the mammary gland in a rat chemically induced breast cancer model.

Manzanares MÁ, Solanas M, Moral R, Escrich R, Vela E, Costa I, Escrich E.

Eur J Cancer Prev. 2015 May;24(3):215-22. doi: 10.1097/CEJ.0000000000000032.

PMID:
24722539
35.

Augmentation of intramembranous bone in rabbit calvaria using an occlusive barrier in combination with demineralized bone matrix (DBM): a pilot study.

Beltrán V, Engelke W, Prieto R, Valdivia-Gandur I, Navarro P, Manzanares MC, Borie E, Fuentes R.

Int J Surg. 2014;12(5):378-83. doi: 10.1016/j.ijsu.2014.03.010. Epub 2014 Mar 18.

36.

Obesity-associated variants within FTO form long-range functional connections with IRX3.

Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, Nagy A, Cox NJ, Hui CC, Gomez-Skarmeta JL, Nóbrega MA.

Nature. 2014 Mar 20;507(7492):371-5. doi: 10.1038/nature13138. Epub 2014 Mar 12.

37.

Functional genomics of cardiovascular development and disease.

Manzanares M.

Brief Funct Genomics. 2014 Jan;13(1):1-2. doi: 10.1093/bfgp/elt043. No abstract available.

PMID:
24448473
38.

Reprogramming in vivo produces teratomas and iPS cells with totipotency features.

Abad M, Mosteiro L, Pantoja C, Cañamero M, Rayon T, Ors I, Graña O, Megías D, Domínguez O, Martínez D, Manzanares M, Ortega S, Serrano M.

Nature. 2013 Oct 17;502(7471):340-5. doi: 10.1038/nature12586. Epub 2013 Sep 11.

PMID:
24025773
39.

Development: Hippo signalling turns the embryo inside out.

Manzanares M, Rodriguez TA.

Curr Biol. 2013 Jul 8;23(13):R559-61. doi: 10.1016/j.cub.2013.05.064.

40.

Productivity in physical and chemical science predicts the future economic growth of developing countries better than other popular indices.

Jaffe K, Caicedo M, Manzanares M, Gil M, Rios A, Florez A, Montoreano C, Davila V.

PLoS One. 2013 Jun 12;8(6):e66239. doi: 10.1371/journal.pone.0066239. Print 2013.

41.

An improved computer vision method for white blood cells detection.

Cuevas E, Díaz M, Manzanares M, Zaldivar D, Perez-Cisneros M.

Comput Math Methods Med. 2013;2013:137392. doi: 10.1155/2013/137392. Epub 2013 May 19.

42.

A new standardized-automatic method for bone-to-implant contact histomorphometric analysis based on backscattered scanning electron microscopy images.

Manresa C, Bosch M, Manzanares MC, Carvalho P, Echeverría JJ.

Clin Oral Implants Res. 2014 Jun;25(6):702-6. doi: 10.1111/clr.12129. Epub 2013 Feb 19.

PMID:
23418782
43.

Understanding cardiovascular disease: a journey through the genome (and what we found there).

Lara-Pezzi E, Dopazo A, Manzanares M.

Dis Model Mech. 2012 Jul;5(4):434-43. doi: 10.1242/dmm.009787. Review.

44.

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.

Martin D, Pantoja C, Fernández Miñán A, Valdes-Quezada C, Moltó E, Matesanz F, Bogdanović O, de la Calle-Mustienes E, Domínguez O, Taher L, Furlan-Magaril M, Alcina A, Cañón S, Fedetz M, Blasco MA, Pereira PS, Ovcharenko I, Recillas-Targa F, Montoliu L, Manzanares M, Guigó R, Serrano M, Casares F, Gómez-Skarmeta JL.

Nat Struct Mol Biol. 2011 Jun;18(6):708-14. doi: 10.1038/nsmb.2059. Epub 2011 May 22. Erratum in: Nat Struct Mol Biol. 2011 Sep;18(9):1084.

45.

An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation.

Tena JJ, Alonso ME, de la Calle-Mustienes E, Splinter E, de Laat W, Manzanares M, Gómez-Skarmeta JL.

Nat Commun. 2011;2:310. doi: 10.1038/ncomms1301.

PMID:
21556064
46.

Pluripotency and lineages in the mammalian blastocyst: an evolutionary view.

Cañon S, Fernandez-Tresguerres B, Manzanares M.

Cell Cycle. 2011 Jun 1;10(11):1731-8. Epub 2011 Jun 1.

PMID:
21527827
47.

MiRNA-mediated regulation of cell signaling and homeostasis in the early mouse embryo.

Pernaute B, Spruce T, Rodriguez TA, Manzanares M.

Cell Cycle. 2011 Feb 15;10(4):584-91. Epub 2011 Feb 15.

PMID:
21293181
48.

Evolution of the mammalian embryonic pluripotency gene regulatory network.

Fernandez-Tresguerres B, Cañon S, Rayon T, Pernaute B, Crespo M, Torroja C, Manzanares M.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19955-60. doi: 10.1073/pnas.1010708107. Epub 2010 Nov 3.

49.

Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

Pittman AM, Naranjo S, Jalava SE, Twiss P, Ma Y, Olver B, Lloyd A, Vijayakrishnan J, Qureshi M, Broderick P, van Wezel T, Morreau H, Tuupanen S, Aaltonen LA, Alonso ME, Manzanares M, Gavilán A, Visakorpi T, Gómez-Skarmeta JL, Houlston RS.

PLoS Genet. 2010 Sep 16;6(9):e1001126. doi: 10.1371/journal.pgen.1001126.

50.

Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

Kouwenhoven EN, van Heeringen SJ, Tena JJ, Oti M, Dutilh BE, Alonso ME, de la Calle-Mustienes E, Smeenk L, Rinne T, Parsaulian L, Bolat E, Jurgelenaite R, Huynen MA, Hoischen A, Veltman JA, Brunner HG, Roscioli T, Oates E, Wilson M, Manzanares M, Gómez-Skarmeta JL, Stunnenberg HG, Lohrum M, van Bokhoven H, Zhou H.

PLoS Genet. 2010 Aug 19;6(8):e1001065. doi: 10.1371/journal.pgen.1001065.

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