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Gabapentin is a potent activator of KCNQ3 and KCNQ5 potassium channels.

Manville RW, Abbott G.

Mol Pharmacol. 2018 Jul 18. pii: mol.118.112953. doi: 10.1124/mol.118.112953. [Epub ahead of print]


Direct neurotransmitter activation of voltage-gated potassium channels.

Manville RW, Papanikolaou M, Abbott GW.

Nat Commun. 2018 May 10;9(1):1847. doi: 10.1038/s41467-018-04266-w.


SMIT1 Modifies KCNQ Channel Function and Pharmacology by Physical Interaction with the Pore.

Manville RW, Neverisky DL, Abbott GW.

Biophys J. 2017 Aug 8;113(3):613-626. doi: 10.1016/j.bpj.2017.06.055.

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