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Items: 1 to 50 of 152

1.

Prokaryotic SPHINX replication sequences are conserved in mammalian brain and participate in neurodegeneration.

Szigeti-Buck K, Manuelidis L.

J Cell Biochem. 2019 Oct;120(10):17687-17698. doi: 10.1002/jcb.29035. Epub 2019 Jun 23.

PMID:
31231867
2.

Prokaryotic SPHINX 1.8 REP protein is tissue-specific and expressed in human germline cells.

Manuelidis L.

J Cell Biochem. 2019 Apr;120(4):6198-6208. doi: 10.1002/jcb.27907. Epub 2018 Oct 14.

PMID:
30317668
3.

A prokaryotic viral sequence is expressed and conserved in mammalian brain.

Yeh YH, Gunasekharan V, Manuelidis L.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7118-7123. doi: 10.1073/pnas.1706110114. Epub 2017 Jun 19.

4.

Virulence profile: Laura Manuelidis.

Manuelidis L.

Virulence. 2016 May 18;7(4):477-80. doi: 10.1080/21505594.2016.1151210. Epub 2016 Feb 8. No abstract available.

5.

CJD and Scrapie Require Agent-Associated Nucleic Acids for Infection.

Botsios S, Manuelidis L.

J Cell Biochem. 2016 Aug;117(8):1947-58. doi: 10.1002/jcb.25495. Epub 2016 Feb 11.

PMID:
26773845
6.

Rapid chemical decontamination of infectious CJD and scrapie particles parallels treatments known to disrupt microbes and biofilms.

Botsios S, Tittman S, Manuelidis L.

Virulence. 2015;6(8):787-801. doi: 10.1080/21505594.2015.1098804.

7.

Proteomic analysis of host brain components that bind to infectious particles in Creutzfeldt-Jakob disease.

Kipkorir T, Colangelo CM, Manuelidis L.

Proteomics. 2015 Sep;15(17):2983-98. doi: 10.1002/pmic.201500059. Epub 2015 Jun 9.

8.

Highly infectious CJD particles lack prion protein but contain many viral-linked peptides by LC-MS/MS.

Kipkorir T, Tittman S, Botsios S, Manuelidis L.

J Cell Biochem. 2014 Nov;115(11):2012-21. doi: 10.1002/jcb.24873.

PMID:
24933657
9.

Infectious particles, stress, and induced prion amyloids: a unifying perspective.

Manuelidis L.

Virulence. 2013 Jul 1;4(5):373-83. doi: 10.4161/viru.24838. Epub 2013 Apr 30. Review.

10.

Continuous production of prions after infectious particles are eliminated: implications for Alzheimer's disease.

Miyazawa K, Kipkorir T, Tittman S, Manuelidis L.

PLoS One. 2012;7(4):e35471. doi: 10.1371/journal.pone.0035471. Epub 2012 Apr 11.

11.

High CJD infectivity remains after prion protein is destroyed.

Miyazawa K, Emmerling K, Manuelidis L.

J Cell Biochem. 2011 Dec;112(12):3630-7. doi: 10.1002/jcb.23286.

12.

Replication and spread of CJD, kuru and scrapie agents in vivo and in cell culture.

Miyazawa K, Emmerling K, Manuelidis L.

Virulence. 2011 May-Jun;2(3):188-99. Epub 2011 May 1.

13.

Transmissible encephalopathy agents: virulence, geography and clockwork.

Manuelidis L.

Virulence. 2010 Mar-Apr;1(2):101-4. doi: 10.4161/viru.1.2.10822.

14.

Nuclease resistant circular DNAs copurify with infectivity in scrapie and CJD.

Manuelidis L.

J Neurovirol. 2011 Apr;17(2):131-45. doi: 10.1007/s13365-010-0007-0. Epub 2010 Dec 7.

PMID:
21165784
15.

Proliferative arrest of neural cells induces prion protein synthesis, nanotube formation, and cell-to-cell contacts.

Miyazawa K, Emmerling K, Manuelidis L.

J Cell Biochem. 2010 Sep 1;111(1):239-47. doi: 10.1002/jcb.22723.

16.

Agent-specific Shadoo responses in transmissible encephalopathies.

Miyazawa K, Manuelidis L.

J Neuroimmune Pharmacol. 2010 Mar;5(1):155-63. doi: 10.1007/s11481-010-9191-1. Epub 2010 Jan 30.

17.

The kuru infectious agent is a unique geographic isolate distinct from Creutzfeldt-Jakob disease and scrapie agents.

Manuelidis L, Chakrabarty T, Miyazawa K, Nduom NA, Emmerling K.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13529-34. doi: 10.1073/pnas.0905825106. Epub 2009 Jul 24.

18.

Strain-specific viral properties of variant Creutzfeldt-Jakob disease (vCJD) are encoded by the agent and not by host prion protein.

Manuelidis L, Liu Y, Mullins B.

J Cell Biochem. 2009 Feb 1;106(2):220-31. doi: 10.1002/jcb.21988.

19.

A rapid accurate culture assay for infectivity in Transmissible Encephalopathies.

Liu Y, Sun R, Chakrabarty T, Manuelidis L.

J Neurovirol. 2008 Oct;14(5):352-61. doi: 10.1080/13550280802105283. Epub 2008 Nov 12.

20.

Quantitative recovery of scrapie agent with minimal protein from highly infectious cultures.

Sun R, Liu Y, Zhang H, Manuelidis L.

Viral Immunol. 2008 Sep;21(3):293-302. doi: 10.1089/vim.2008.0039.

21.

Penny wise, pound foolish-a retrospective.

Manuelidis L.

Science. 2000 Dec 22;290(5500):2257b. No abstract available.

PMID:
17774594
22.

Cells infected with scrapie and Creutzfeldt-Jakob disease agents produce intracellular 25-nm virus-like particles.

Manuelidis L, Yu ZX, Barquero N, Mullins B.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1965-70. Epub 2007 Jan 31. Erratum in: Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6090. Banquero, Nuria [corrected to Barquero, Nuria].

23.

A 25 nm virion is the likely cause of transmissible spongiform encephalopathies.

Manuelidis L.

J Cell Biochem. 2007 Mar 1;100(4):897-915. Review.

PMID:
17044041
24.

A virus behind the mask of prions?

Manuelidis L.

Folia Neuropathol. 2004;42 Suppl B:10-23. Review.

PMID:
16903139
25.

Reciprocal interference between specific CJD and scrapie agents in neural cell cultures.

Nishida N, Katamine S, Manuelidis L.

Science. 2005 Oct 21;310(5747):493-6.

26.

New molecular markers of early and progressive CJD brain infection.

Lu ZY, Baker CA, Manuelidis L.

J Cell Biochem. 2004 Nov 1;93(4):644-52.

PMID:
15660413
27.

Two Creutzfeldt-Jakob disease agents reproduce prion protein-independent identities in cell cultures.

Arjona A, Simarro L, Islinger F, Nishida N, Manuelidis L.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8768-73. Epub 2004 May 25.

28.

Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells.

Psyrri A, DeFilippis RA, Edwards AP, Yates KE, Manuelidis L, DiMaio D.

Cancer Res. 2004 May 1;64(9):3079-86.

30.

Early induction of interferon-responsive mRNAs in Creutzfeldt-Jakob disease.

Baker CA, Lu ZY, Manuelidis L.

J Neurovirol. 2004 Feb;10(1):29-40.

31.

Transmissible encephalopathies: speculations and realities.

Manuelidis L.

Viral Immunol. 2003;16(2):123-39. Review.

PMID:
12828865
32.

Virus-like interference in the latency and prevention of Creutzfeldt-Jakob disease.

Manuelidis L, Lu ZY.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5360-5. Epub 2003 Apr 11.

33.

Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease.

Baker CA, Manuelidis L.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):675-9. Epub 2003 Jan 13.

34.
35.
36.

Blood borne transit of CJD from brain to gut at early stages of infection.

Radebold K, Chernyak M, Martin D, Manuelidis L.

BMC Infect Dis. 2001;1:20. Epub 2001 Oct 25.

37.

Gap junctional channels regulate acid secretion in the mammalian gastric gland.

Radebold K, Horakova E, Gloeckner J, Ortega G, Spray DC, Vieweger H, Siebert K, Manuelidis L, Geibel JP.

J Membr Biol. 2001 Oct 1;183(3):147-53.

PMID:
11696856
38.

The stomach divalent ion-sensing receptor scar is a modulator of gastric acid secretion.

Geibel JP, Wagner CA, Caroppo R, Qureshi I, Gloeckner J, Manuelidis L, Kirchhoff P, Radebold K.

J Biol Chem. 2001 Oct 26;276(43):39549-52. Epub 2001 Aug 15.

39.

Neuroinvasion by a Creutzfeldt-Jakob disease agent in the absence of B cells and follicular dendritic cells.

Shlomchik MJ, Radebold K, Duclos N, Manuelidis L.

Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9289-94. Epub 2001 Jul 24.

40.

Penny wise, pound foolish--a retrospective.

Manuelidis L.

Science. 2000 Dec 22;290(5500):2257. No abstract available.

PMID:
11188719
41.

Attenuated Creutzfeldt-Jakob Disease agents can hide more virulent infections.

Manuelidis L, Yun Lu Z.

Neurosci Lett. 2000 Nov 3;293(3):163-6.

PMID:
11036186
42.

Follicular dendritic cells and dissemination of Creutzfeldt-Jakob disease.

Manuelidis L, Zaitsev I, Koni P, Lu ZY, Flavell RA, Fritch W.

J Virol. 2000 Sep;74(18):8614-22.

43.

Antiscrapie drug action.

Manuelidis L.

Science. 2000 Apr 14;288(5464):273-4. No abstract available.

PMID:
10777407
44.

Microglial activation varies in different models of Creutzfeldt-Jakob disease.

Baker CA, Lu ZY, Zaitsev I, Manuelidis L.

J Virol. 1999 Jun;73(6):5089-97.

45.

Changes in N-acetylaspartate and myo-inositol detected in the cerebral cortex of hamsters with Creutzfeldt-Jakob disease.

Behar KL, Boucher R, Fritch W, Manuelidis L.

Magn Reson Imaging. 1998 Oct;16(8):963-8.

PMID:
9814779
46.

Cleaning CJD-contaminated instruments.

Manuelidis L.

Science. 1998 Sep 25;281(5385):1961. No abstract available.

PMID:
9767039
47.

Dapsone to delay symptoms in Creutzfeldt-Jakob disease.

Manuelidis L, Fritch W, Zaitsev I.

Lancet. 1998 Aug 8;352(9126):456. No abstract available.

PMID:
9708762
48.
49.

Evolution of a strain of CJD that induces BSE-like plaques.

Manuelidis L, Fritch W, Xi YG.

Science. 1997 Jul 4;277(5322):94-8.

50.

Human A beta-amyloid and amyloid precursor protein accumulates in rat brain cells after cultured human leptomeningeal fibroblast implants.

DeGiorgio LA, Bernstein JJ, Manuelidis L, Blass JP.

Brain Res. 1997 Mar 28;752(1-2):35-44.

PMID:
9106438

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