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Items: 40

1.

Prevalence and predictors of adherence to controller therapy in adult patients with severe/difficult-to-treat asthma: a systematic review and meta-analysis.

Hassan M, Davies SE, Trethewey SP, Mansur AH.

J Asthma. 2019 Jul 30:1-10. doi: 10.1080/02770903.2019.1645169. [Epub ahead of print]

PMID:
31311359
2.

Change in type-2 biomarkers and related cytokines with prednisolone in uncontrolled severe oral corticosteroid dependent asthmatics: an interventional open-label study.

Busby J, Holweg CTJ, Chai A, Bradding P, Cai F, Chaudhuri R, Mansur AH, Lordan JL, Matthews JG, Menzies-Gow A, Niven R, Staton T, Heaney LG.

Thorax. 2019 Aug;74(8):806-809. doi: 10.1136/thoraxjnl-2018-212709. Epub 2019 Apr 2.

PMID:
30940770
3.

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Lewis J, Henry AP, Billington CK, Ahmad A, Packer RJ, Shaw D, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Djukanovic R, Hankinson J, Niven R, Simpson A, Chung KF, Sterk PJ, Blakey JD, Adcock IM, Hu S, Guo Y, Obeidat M, Sin DD, van den Berge M, Nickle DC, Bossé Y, Tobin MD, Hall IP, Brightling CE, Wain LV, Sayers I.

Lancet Respir Med. 2019 Jan;7(1):20-34. doi: 10.1016/S2213-2600(18)30389-8. Epub 2018 Dec 11.

4.

Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Nonadherence in Severe Asthma.

Heaney LG, Busby J, Bradding P, Chaudhuri R, Mansur AH, Niven R, Pavord ID, Lindsay JT, Costello RW; Medical Research Council UK Refractory Asthma Stratification Programme (RASP-UK).

Am J Respir Crit Care Med. 2019 Feb 15;199(4):454-464. doi: 10.1164/rccm.201806-1182OC.

PMID:
30339770
5.

Disconnect of type 2 biomarkers in severe asthma; dominated by FeNO as a predictor of exacerbations and periostin as predictor of reduced lung function.

Mansur AH, Srivastava S, Sahal A.

Respir Med. 2018 Oct;143:31-38. doi: 10.1016/j.rmed.2018.08.005. Epub 2018 Aug 9.

PMID:
30261989
6.

Does Continuous Positive Airway Pressure (CPAP) treatment of obstructive sleep apnoea (OSA) improve asthma-related clinical outcomes in patients with co-existing conditions?- A systematic review.

Davies SE, Bishopp A, Wharton S, Turner AM, Mansur AH.

Respir Med. 2018 Oct;143:18-30. doi: 10.1016/j.rmed.2018.08.004. Epub 2018 Aug 9.

PMID:
30261988
7.

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss.

Chernyavsky IL, Russell RJ, Saunders RM, Morris GE, Berair R, Singapuri A, Chachi L, Mansur AH, Howarth PH, Dennison P, Chaudhuri R, Bicknell S, Rose FRAJ, Siddiqui S, Brook BS, Brightling CE.

Eur Respir J. 2018 May 24;51(5). pii: 1701680. doi: 10.1183/13993003.01680-2017. Print 2018 May.

8.

Assessment of an accessorized pre-filled syringe for home-administered benralizumab in severe asthma.

Ferguson GT, Mansur AH, Jacobs JS, Hebert J, Clawson C, Tao W, Wu Y, Goldman M.

J Asthma Allergy. 2018 Apr 5;11:63-72. doi: 10.2147/JAA.S157762. eCollection 2018.

9.

The association between asthma and obstructive sleep apnea (OSA): A systematic review.

Davies SE, Bishopp A, Wharton S, Turner AM, Mansur AH.

J Asthma. 2019 Feb;56(2):118-129. doi: 10.1080/02770903.2018.1444049. Epub 2018 Apr 11.

PMID:
29641292
10.

A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial.

Hanratty CE, Matthews JG, Arron JR, Choy DF, Pavord ID, Bradding P, Brightling CE, Chaudhuri R, Cowan DC, Djukanovic R, Gallagher N, Fowler SJ, Hardman TC, Harrison T, Holweg CT, Howarth PH, Lordan J, Mansur AH, Menzies-Gow A, Mosesova S, Niven RM, Robinson DS, Shaw DE, Walker S, Woodcock A, Heaney LG; RASP-UK (Refractory Asthma Stratification Programme) Consortium.

Trials. 2018 Jan 4;19(1):5. doi: 10.1186/s13063-017-2384-7.

11.

Biomarkers of oxidative stress and antioxidants in severe asthma: A Prospective Case-Control Study.

Bishopp A, Sathyamurthy R, Manney S, Webbster C, Krishna MT, Mansur AH.

Ann Allergy Asthma Immunol. 2017 Apr;118(4):445-451. doi: 10.1016/j.anai.2017.02.004.

PMID:
28390585
12.

Longterm clinical outcomes of omalizumab therapy in severe allergic asthma: Study of efficacy and safety.

Mansur AH, Srivastava S, Mitchell V, Sullivan J, Kasujee I.

Respir Med. 2017 Mar;124:36-43. doi: 10.1016/j.rmed.2017.01.008. Epub 2017 Jan 25.

13.

Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma.

Chaudhuri R, McSharry C, Heaney LG, Niven R, Brightling CE, Menzies-Gow AN, Bucknall C, Mansur AH, Lee W, Shepherd M, Spears M, Cowan DC, Husi H, Thomson NC; BTS Severe Asthma Network.

Respir Med. 2016 Sep;118:46-52. doi: 10.1016/j.rmed.2016.07.005. Epub 2016 Jul 9.

14.

Impact of omalizumab on treatment of severe allergic asthma in UK clinical practice: a UK multicentre observational study (the APEX II study).

Niven RM, Saralaya D, Chaudhuri R, Masoli M, Clifton I, Mansur AH, Hacking V, McLain-Smith S, Menzies-Gow A.

BMJ Open. 2016 Aug 9;6(8):e011857. doi: 10.1136/bmjopen-2016-011857.

15.

Fevipiprant, a prostaglandin D2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial.

Gonem S, Berair R, Singapuri A, Hartley R, Laurencin MFM, Bacher G, Holzhauer B, Bourne M, Mistry V, Pavord ID, Mansur AH, Wardlaw AJ, Siddiqui SH, Kay RA, Brightling CE.

Lancet Respir Med. 2016 Sep;4(9):699-707. doi: 10.1016/S2213-2600(16)30179-5. Epub 2016 Aug 5.

PMID:
27503237
16.

Long-Term Fluticasone Propionate/Formoterol Fumarate Combination Therapy Is Associated with a Low Incidence of Severe Asthma Exacerbations.

Papi A, Mansur AH, Pertseva T, Kaiser K, McIver T, Grothe B, Dissanayake S.

J Aerosol Med Pulm Drug Deliv. 2016 Aug;29(4):346-61. doi: 10.1089/jamp.2015.1255. Epub 2016 Apr 22.

17.

Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry.

Sweeney J, Patterson CC, Menzies-Gow A, Niven RM, Mansur AH, Bucknall C, Chaudhuri R, Price D, Brightling CE, Heaney LG; British Thoracic Society Difficult Asthma Network.

Thorax. 2016 Apr;71(4):339-46. doi: 10.1136/thoraxjnl-2015-207630. Epub 2016 Jan 27.

PMID:
26819354
18.

Dedicated severe asthma services improve health-care use and quality of life.

Gibeon D, Heaney LG, Brightling CE, Niven R, Mansur AH, Chaudhuri R, Bucknall CE, Menzies-Gow AN; British Thoracic Society Difficult Asthma Network.

Chest. 2015 Oct;148(4):870-876. doi: 10.1378/chest.14-3056.

PMID:
25789861
19.

Continuous terbutaline infusion in severe asthma in adults: a retrospective study of long-term efficacy and safety.

Mansur AH, Afridi L, Sullivan J, Ayres JG, Wilson D.

J Asthma. 2014 Dec;51(10):1076-82. doi: 10.3109/02770903.2014.939281. Epub 2014 Aug 11.

PMID:
25019350
20.

The cost of treating severe refractory asthma in the UK: an economic analysis from the British Thoracic Society Difficult Asthma Registry.

O'Neill S, Sweeney J, Patterson CC, Menzies-Gow A, Niven R, Mansur AH, Bucknall C, Chaudhuri R, Thomson NC, Brightling CE, O'Neill C, Heaney LG; British Thoracic Society Difficult Asthma Network.

Thorax. 2015 Apr;70(4):376-8. doi: 10.1136/thoraxjnl-2013-204114. Epub 2014 Jun 10.

PMID:
24917087
21.

Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma.

Wechsler ME, Laviolette M, Rubin AS, Fiterman J, Lapa e Silva JR, Shah PL, Fiss E, Olivenstein R, Thomson NC, Niven RM, Pavord ID, Simoff M, Hales JB, McEvoy C, Slebos DJ, Holmes M, Phillips MJ, Erzurum SC, Hanania NA, Sumino K, Kraft M, Cox G, Sterman DH, Hogarth K, Kline JN, Mansur AH, Louie BE, Leeds WM, Barbers RG, Austin JH, Shargill NS, Quiring J, Armstrong B, Castro M; Asthma Intervention Research 2 Trial Study Group.

J Allergy Clin Immunol. 2013 Dec;132(6):1295-302. doi: 10.1016/j.jaci.2013.08.009. Epub 2013 Aug 30.

22.

Effectiveness of omalizumab in severe allergic asthma: a retrospective UK real-world study.

Barnes N, Menzies-Gow A, Mansur AH, Spencer D, Percival F, Radwan A, Niven R.

J Asthma. 2013 Jun;50(5):529-36. doi: 10.3109/02770903.2013.790419. Epub 2013 May 14.

23.

Catamenial hemoptysis.

Singh K, Agarwal S, Bishay E, Trotter S, Mansur AH.

Am J Respir Crit Care Med. 2013 Mar 15;187(6):658. doi: 10.1164/rccm.201209-1579IM. No abstract available.

PMID:
23504362
24.

Clinical outcomes and inflammatory biomarkers in current smokers and exsmokers with severe asthma.

Thomson NC, Chaudhuri R, Heaney LG, Bucknall C, Niven RM, Brightling CE, Menzies-Gow AN, Mansur AH, McSharry C.

J Allergy Clin Immunol. 2013 Apr;131(4):1008-16. doi: 10.1016/j.jaci.2012.12.1574. Epub 2013 Feb 16.

PMID:
23419540
25.

Long-term safety and efficacy of fluticasone/formoterol combination therapy in asthma.

Mansur AH, Kaiser K.

J Aerosol Med Pulm Drug Deliv. 2013 Aug;26(4):190-9. doi: 10.1089/jamp.2012.0977. Epub 2012 Oct 25.

PMID:
23098325
26.

Association between exhaled breath condensate nitrate + nitrite levels with ambient coarse particle exposure in subjects with airways disease.

Manney S, Meddings CM, Harrison RM, Mansur AH, Karakatsani A, Analitis A, Katsouyanni K, Perifanou D, Kavouras IG, Kotronarou N, de Hartog JJ, Pekkanen J, Hämeri K, ten Brink H, Hoek G, Ayres JG.

Occup Environ Med. 2012 Sep;69(9):663-9. doi: 10.1136/oemed-2011-100255. Epub 2012 Jul 5.

PMID:
22767867
27.

Genome-wide association study to identify genetic determinants of severe asthma.

Wan YI, Shrine NR, Soler Artigas M, Wain LV, Blakey JD, Moffatt MF, Bush A, Chung KF, Cookson WO, Strachan DP, Heaney L, Al-Momani BA, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Hui J, Musk AW, James AL; Australian Asthma Genetics Consortium, Brown MA, Baltic S, Ferreira MA, Thompson PJ, Tobin MD, Sayers I, Hall IP.

Thorax. 2012 Sep;67(9):762-8. Epub 2012 May 5.

28.

Vocal cord dysfunction and severe asthma: considering the total airway.

Ayres JG, Mansur AH.

Am J Respir Crit Care Med. 2011 Jul 1;184(1):2-3. doi: 10.1164/rccm.201103-0582ED. No abstract available.

PMID:
21737588
29.

Secretoglobin 1A1 gene and asthma pre-disposition: what is the evidence?

Mansur AH.

Clin Exp Allergy. 2009 Jan;39(1):8-11. doi: 10.1111/j.1365-2222.2008.03161.x. No abstract available.

PMID:
19128350
30.

Methacholine-induced asthma symptoms correlate with impulse oscillometry but not spirometry.

Mansur AH, Manney S, Ayres JG.

Respir Med. 2008 Jan;102(1):42-9. Epub 2007 Sep 27.

31.

A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects.

Lakind JS, Holgate ST, Ownby DR, Mansur AH, Helms PJ, Pyatt D, Hays SM.

Biomarkers. 2007 Sep-Oct;12(5):445-67. Review.

PMID:
17701745
32.

Vocal cord dysfunction treated with long-term tracheostomy: 2 case studies.

Park DP, Ayres JG, McLeod DT, Mansur AH.

Ann Allergy Asthma Immunol. 2007 Jun;98(6):591-4.

PMID:
17601276
33.

Linkage/association study of a locus modulating total serum IgE on chromosome 14q13-24 in families with asthma.

Mansur AH, Bishop DT, Holgate ST, Markham AF, Morrison JF.

Thorax. 2004 Oct;59(10):876-82.

34.

An association study between the Clara cell secretory protein CC16 A38G polymorphism and asthma phenotypes.

Mansur AH, Fryer AA, Hepple M, Strange RC, Spiteri MA.

Clin Exp Allergy. 2002 Jul;32(7):994-9.

PMID:
12100044
35.

Evidence for a role of HLA DRB1 alleles in the control of IgE levels, strengthened by interacting TCR A/D marker alleles.

Mansur AH, Williams GA, Bishop DT, Markham AF, Lewis S, Britton J, Morrison JF.

Clin Exp Allergy. 2000 Oct;30(10):1371-8.

PMID:
10998012
36.

Lack of linkage between chromosome 5q23-33 markers and IgE/bronchial hyperreactivity in 67 Scottish families.

Mansur AH, Christie G, Turner A, Bishop DT, Markham AF, Helms P, Morrison JF.

Clin Exp Allergy. 2000 Jul;30(7):954-61.

PMID:
10848917
37.

Association between - 308 tumour necrosis factor promoter polymorphism and bronchial hyperreactivity in asthma.

Li Kam Wa TC, Mansur AH, Britton J, Williams G, Pavord I, Richards K, Campbell DA, Morton N, Holgate ST, Morrison JF.

Clin Exp Allergy. 1999 Sep;29(9):1204-8.

PMID:
10469028
38.

Suggestive evidence for genetic linkage between IgE phenotypes and chromosome 14q markers.

Mansur AH, Bishop DT, Markham AF, Morton NE, Holgate ST, Morrison JF.

Am J Respir Crit Care Med. 1999 Jun;159(6):1796-802.

PMID:
10351921
39.

Association study of asthma and atopy traits and chromosome 5q cytokine cluster markers.

Mansur AH, Bishop DT, Markham AF, Britton J, Morrison JF.

Clin Exp Allergy. 1998 Feb;28(2):141-50.

PMID:
9515585
40.

Non random usage of T cell receptor alpha gene expression in atopy using anchored PCR.

Mansur AH, Gelder CM, Holland D, Campell DA, Griffin A, Cunliffe W, Markham AF, Morrison JF.

Adv Exp Med Biol. 1996;409:381-9.

PMID:
9095269

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