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Items: 1 to 50 of 152

1.

Actin-tropomyosin distribution in non-muscle cells.

Manstein DJ, Meiring JCM, Hardeman EC, Gunning PW.

J Muscle Res Cell Motil. 2019 May 4. doi: 10.1007/s10974-019-09514-0. [Epub ahead of print]

PMID:
31054005
2.

Optimization-based vessel segmentation pipeline for robust quantification of capillary networks in skin with optical coherence tomography angiography.

Casper M, Schulz-Hildebrandt H, Evers M, Birngruber R, Manstein D, Hüttmann G.

J Biomed Opt. 2019 Apr;24(4):1-11. doi: 10.1117/1.JBO.24.4.046005.

PMID:
31041858
3.

Phenamacril is a reversible and noncompetitive inhibitor of Fusarium class I myosin.

Wollenberg RD, Taft MH, Giese S, Thiel C, Balázs Z, Giese H, Manstein DJ, Sondergaard TE.

J Biol Chem. 2019 Jan 25;294(4):1328-1337. doi: 10.1074/jbc.RA118.005408. Epub 2018 Nov 30.

PMID:
30504222
4.

Author Correction: Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia.

Latham SL, Ehmke N, Reinke PYA, Taft MH, Eicke D, Reindl T, Stenzel W, Lyons MJ, Friez MJ, Lee JA, Hecker R, Frühwald MC, Becker K, Neuhann TM, Horn D, Schrock E, Niehaus I, Sarnow K, Grützmann K, Gawehn L, Klink B, Rump A, Chaponnier C, Figueiredo C, Knöfler R, Manstein DJ, Di Donato N.

Nat Commun. 2018 Nov 19;9(1):4930. doi: 10.1038/s41467-018-07404-6.

5.

Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia.

Latham SL, Ehmke N, Reinke PYA, Taft MH, Eicke D, Reindl T, Stenzel W, Lyons MJ, Friez MJ, Lee JA, Hecker R, Frühwald MC, Becker K, Neuhann TM, Horn D, Schrock E, Niehaus I, Sarnow K, Grützmann K, Gawehn L, Klink B, Rump A, Chaponnier C, Figueiredo C, Knöfler R, Manstein DJ, Di Donato N.

Nat Commun. 2018 Oct 12;9(1):4250. doi: 10.1038/s41467-018-06713-0. Erratum in: Nat Commun. 2018 Nov 19;9(1):4930.

6.

Treatments targeting inotropy.

Maack C, Eschenhagen T, Hamdani N, Heinzel FR, Lyon AR, Manstein DJ, Metzger J, Papp Z, Tocchetti CG, Yilmaz MB, Anker SD, Balligand JL, Bauersachs J, Brutsaert D, Carrier L, Chlopicki S, Cleland JG, de Boer RA, Dietl A, Fischmeister R, Harjola VP, Heymans S, Hilfiker-Kleiner D, Holzmeister J, de Keulenaer G, Limongelli G, Linke WA, Lund LH, Masip J, Metra M, Mueller C, Pieske B, Ponikowski P, Ristic A, Ruschitzka F, Seferovic PM, Skouri H, Zimmermann WH, Mebazaa A.

Eur Heart J. 2018 Oct 8. doi: 10.1093/eurheartj/ehy600. [Epub ahead of print]

PMID:
30295807
7.

Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton.

Meiring JCM, Bryce NS, Wang Y, Taft MH, Manstein DJ, Liu Lau S, Stear J, Hardeman EC, Gunning PW.

Curr Biol. 2018 Jul 23;28(14):2331-2337.e5. doi: 10.1016/j.cub.2018.05.053. Epub 2018 Jul 5.

8.

Enhanced quantification of metabolic activity for individual adipocytes by label-free FLIM.

Evers M, Salma N, Osseiran S, Casper M, Birngruber R, Evans CL, Manstein D.

Sci Rep. 2018 Jun 8;8(1):8757. doi: 10.1038/s41598-018-27093-x.

9.

Assessment of skin lesions produced by focused, tunable, mid-infrared chalcogenide laser radiation.

Evers M, Ha L, Casper M, Welford D, Kositratna G, Birngruber R, Manstein D.

Lasers Surg Med. 2018 Sep;50(9):961-972. doi: 10.1002/lsm.22935. Epub 2018 May 25.

PMID:
29799127
10.
11.

Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C.

Chinthalapudi K, Heissler SM, Preller M, Sellers JR, Manstein DJ.

Elife. 2017 Dec 19;6. pii: e32742. doi: 10.7554/eLife.32742.

12.

Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actin in vitro.

Pathan-Chhatbar S, Taft MH, Reindl T, Hundt N, Latham SL, Manstein DJ.

J Biol Chem. 2018 Jan 19;293(3):863-875. doi: 10.1074/jbc.M117.806521. Epub 2017 Nov 30.

13.

Pink-beam serial crystallography.

Meents A, Wiedorn MO, Srajer V, Henning R, Sarrou I, Bergtholdt J, Barthelmess M, Reinke PYA, Dierksmeyer D, Tolstikova A, Schaible S, Messerschmidt M, Ogata CM, Kissick DJ, Taft MH, Manstein DJ, Lieske J, Oberthuer D, Fischetti RF, Chapman HN.

Nat Commun. 2017 Nov 3;8(1):1281. doi: 10.1038/s41467-017-01417-3.

14.

Fractional Laser Releases Tumor-Associated Antigens in Poorly Immunogenic Tumor and Induces Systemic Immunity.

Kawakubo M, Cunningham TJ, Demehri S, Manstein D.

Sci Rep. 2017 Oct 6;7(1):12751. doi: 10.1038/s41598-017-13095-8.

15.

Inward H+ pump xenorhodopsin: Mechanism and alternative optogenetic approach.

Shevchenko V, Mager T, Kovalev K, Polovinkin V, Alekseev A, Juettner J, Chizhov I, Bamann C, Vavourakis C, Ghai R, Gushchin I, Borshchevskiy V, Rogachev A, Melnikov I, Popov A, Balandin T, Rodriguez-Valera F, Manstein DJ, Bueldt G, Bamberg E, Gordeliy V.

Sci Adv. 2017 Sep 22;3(9):e1603187. doi: 10.1126/sciadv.1603187. eCollection 2017 Sep.

16.

Fractional laser exposure induces neutrophil infiltration (N1 phenotype) into the tumor and stimulates systemic anti-tumor immune response.

Kawakubo M, Demehri S, Manstein D.

PLoS One. 2017 Sep 18;12(9):e0184852. doi: 10.1371/journal.pone.0184852. eCollection 2017.

17.

N-terminal splicing extensions of the human MYO1C gene fine-tune the kinetics of the three full-length myosin IC isoforms.

Zattelman L, Regev R, Ušaj M, Reinke PYA, Giese S, Samson AO, Taft MH, Manstein DJ, Henn A.

J Biol Chem. 2017 Oct 27;292(43):17804-17818. doi: 10.1074/jbc.M117.794008. Epub 2017 Sep 11.

18.

Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism.

Hirschmann F, Krause F, Baruch P, Chizhov I, Mueller JW, Manstein DJ, Papenbrock J, Fedorov R.

Sci Rep. 2017 Jun 23;7(1):4160. doi: 10.1038/s41598-017-04539-2.

19.

Tropomyosin Isoforms Specify Functionally Distinct Actin Filament Populations In Vitro.

Gateva G, Kremneva E, Reindl T, Kotila T, Kogan K, Gressin L, Gunning PW, Manstein DJ, Michelot A, Lappalainen P.

Curr Biol. 2017 Mar 6;27(5):705-713. doi: 10.1016/j.cub.2017.01.018. Epub 2017 Feb 16.

20.

Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma.

Trousil S, Chen S, Mu C, Shaw FM, Yao Z, Ran Y, Shakuntala T, Merghoub T, Manstein D, Rosen N, Cantley LC, Zippin JH, Zheng B.

J Invest Dermatol. 2017 May;137(5):1135-1143. doi: 10.1016/j.jid.2017.01.013. Epub 2017 Jan 28.

21.

Special dermatology/plastic surgery issue 2017.

Manstein D.

Lasers Surg Med. 2017 Jan;49(1):3-6. doi: 10.1002/lsm.22623. Epub 2017 Jan 27. No abstract available.

PMID:
28129437
22.

Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.

von der Ecken J, Heissler SM, Pathan-Chhatbar S, Manstein DJ, Raunser S.

Nature. 2016 Jun 30;534(7609):724-8. Epub 2016 Jun 20.

PMID:
27324845
23.

Tropomyosin-Mediated Regulation of Cytoplasmic Myosins.

Manstein DJ, Mulvihill DP.

Traffic. 2016 Aug;17(8):872-7. doi: 10.1111/tra.12399. Epub 2016 May 4. Review.

24.

Load-dependent modulation of non-muscle myosin-2A function by tropomyosin 4.2.

Hundt N, Steffen W, Pathan-Chhatbar S, Taft MH, Manstein DJ.

Sci Rep. 2016 Feb 5;6:20554. doi: 10.1038/srep20554.

25.

Effects of deviation from focal plane on lesion geometry for ablative fractional photothermolysis.

Kositratna G, Hibert ML, Jaspan M, Welford D, Manstein D.

Lasers Surg Med. 2016 Jul;48(5):555-61. doi: 10.1002/lsm.22481. Epub 2016 Feb 4.

PMID:
26842919
26.

Rapid fibrin plug formation within cutaneous ablative fractional CO2 laser lesions.

Kositratna G, Evers M, Sajjadi A, Manstein D.

Lasers Surg Med. 2016 Feb;48(2):125-32. doi: 10.1002/lsm.22412. Epub 2015 Sep 21.

PMID:
26388136
27.

Crystal structure of the dynamin tetramer.

Reubold TF, Faelber K, Plattner N, Posor Y, Ketel K, Curth U, Schlegel J, Anand R, Manstein DJ, Noé F, Haucke V, Daumke O, Eschenburg S.

Nature. 2015 Sep 17;525(7569):404-8. doi: 10.1038/nature14880. Epub 2015 Aug 24.

PMID:
26302298
28.

The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity.

Lohöfener J, Steinke N, Kay-Fedorov P, Baruch P, Nikulin A, Tishchenko S, Manstein DJ, Fedorov R.

Structure. 2015 May 5;23(5):851-862. doi: 10.1016/j.str.2015.03.012. Epub 2015 Apr 16.

29.

Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion.

Brandstaetter H, Kishi-Itakura C, Tumbarello DA, Manstein DJ, Buss F.

Autophagy. 2014;10(12):2310-23. doi: 10.4161/15548627.2014.984272.

30.

Structure of the F-actin-tropomyosin complex.

von der Ecken J, Müller M, Lehman W, Manstein DJ, Penczek PA, Raunser S.

Nature. 2015 Mar 5;519(7541):114-7. doi: 10.1038/nature14033. Epub 2014 Dec 1.

31.

Crystal structure of the rigor-like human non-muscle myosin-2 motor domain.

Münnich S, Pathan-Chhatbar S, Manstein DJ.

FEBS Lett. 2014 Dec 20;588(24):4754-60. doi: 10.1016/j.febslet.2014.11.007. Epub 2014 Nov 15.

32.

Developing technology: ablative fractional lasers enhance topical drug delivery.

Erlendsson AM, Anderson RR, Manstein D, Waibel JS.

Dermatol Surg. 2014 Dec;40 Suppl 12:S142-6. doi: 10.1097/DSS.0000000000000207. Review. No abstract available.

PMID:
25417565
33.

Molecular mechanisms of disease-related human β-actin mutations p.R183W and p.E364K.

Hundt N, Preller M, Swolski O, Ang AM, Mannherz HG, Manstein DJ, Müller M.

FEBS J. 2014 Dec;281(23):5279-91. doi: 10.1111/febs.13068. Epub 2014 Oct 13.

34.

Micro-fractional epidermal powder delivery for improved skin vaccination.

Chen X, Kositratna G, Zhou C, Manstein D, Wu MX.

J Control Release. 2014 Oct 28;192:310-6. doi: 10.1016/j.jconrel.2014.08.006. Epub 2014 Aug 15.

35.

Expression, purification and crystallization of a dye-decolourizing peroxidase from Dictyostelium discoideum.

Rai A, Fedorov R, Manstein DJ.

Acta Crystallogr F Struct Biol Commun. 2014 Feb;70(Pt 2):252-5. doi: 10.1107/S2053230X14000545. Epub 2014 Jan 22.

36.

Crystal structure of human myosin 1c--the motor in GLUT4 exocytosis: implications for Ca2+ regulation and 14-3-3 binding.

Münnich S, Taft MH, Manstein DJ.

J Mol Biol. 2014 May 15;426(10):2070-81. doi: 10.1016/j.jmb.2014.03.004. Epub 2014 Mar 14.

PMID:
24636949
37.

Small molecule-mediated refolding and activation of myosin motor function.

Radke MB, Taft MH, Stapel B, Hilfiker-Kleiner D, Preller M, Manstein DJ.

Elife. 2014 Feb 11;3:e01603. doi: 10.7554/eLife.01603.

38.

Photosensitizer fluorescence and singlet oxygen luminescence as dosimetric predictors of topical 5-aminolevulinic acid photodynamic therapy induced clinical erythema.

Mallidi S, Anbil S, Lee S, Manstein D, Elrington S, Kositratna G, Schoenfeld D, Pogue B, Davis SJ, Hasan T.

J Biomed Opt. 2014 Feb;19(2):028001. doi: 10.1117/1.JBO.19.2.028001.

39.

Myosin structure, allostery, and mechano-chemistry.

Preller M, Manstein DJ.

Structure. 2013 Nov 5;21(11):1911-22. doi: 10.1016/j.str.2013.09.015. Review.

40.

Kinetic and thermodynamic analysis of the light-induced processes in plant and cyanobacterial phytochromes.

Chizhov I, Zorn B, Manstein DJ, Gärtner W.

Biophys J. 2013 Nov 5;105(9):2210-20. doi: 10.1016/j.bpj.2013.09.033.

41.

Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.

Taft MH, Behrmann E, Munske-Weidemann LC, Thiel C, Raunser S, Manstein DJ.

J Biol Chem. 2013 Oct 18;288(42):30029-41. doi: 10.1074/jbc.M113.497180. Epub 2013 Aug 29.

42.

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human myosin 1c in complex with calmodulin.

Münnich S, Manstein DJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Sep;69(Pt 9):1020-2. doi: 10.1107/S1744309113020988. Epub 2013 Aug 21.

43.

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML.

Chaturvedi A, Araujo Cruz MM, Jyotsana N, Sharma A, Yun H, Görlich K, Wichmann M, Schwarzer A, Preller M, Thol F, Meyer J, Haemmerle R, Struys EA, Jansen EE, Modlich U, Li Z, Sly LM, Geffers R, Lindner R, Manstein DJ, Lehmann U, Krauter J, Ganser A, Heuser M.

Blood. 2013 Oct 17;122(16):2877-87. doi: 10.1182/blood-2013-03-491571. Epub 2013 Aug 16.

44.

Distinct functional interactions between actin isoforms and nonsarcomeric myosins.

Müller M, Diensthuber RP, Chizhov I, Claus P, Heissler SM, Preller M, Taft MH, Manstein DJ.

PLoS One. 2013 Jul 26;8(7):e70636. doi: 10.1371/journal.pone.0070636. Print 2013.

45.

Gene profiling analysis of the early effects of ablative fractional carbon dioxide laser treatment on human skin.

Kim JE, Won CH, Bak H, Kositratna G, Manstein D, Dotto GP, Chang SE.

Dermatol Surg. 2013 Jul;39(7):1033-43. doi: 10.1111/dsu.12170. Epub 2013 Mar 14.

PMID:
23489371
46.

Functional dissection of the dictyostelium discoideum dynamin B mitochondrial targeting sequence.

Rai A, Tzvetkov N, Manstein DJ.

PLoS One. 2013;8(2):e56975. doi: 10.1371/journal.pone.0056975. Epub 2013 Feb 21.

47.

Ulceration of mature surgical scars following nonablative fractional photothermolysis associated with intralesional lidocaine injections.

Chuang GS, Manstein D, Tannous Z, Avram MM.

Dermatol Surg. 2012 Nov;38(11):1879-81. doi: 10.1111/j.1524-4725.2012.02576.x. Epub 2012 Sep 13. No abstract available.

PMID:
22973818
48.

Kinetic properties and small-molecule inhibition of human myosin-6.

Heissler SM, Selvadurai J, Bond LM, Fedorov R, Kendrick-Jones J, Buss F, Manstein DJ.

FEBS Lett. 2012 Sep 21;586(19):3208-14. doi: 10.1016/j.febslet.2012.07.014. Epub 2012 Jul 31.

49.

Structure of the rigor actin-tropomyosin-myosin complex.

Behrmann E, Müller M, Penczek PA, Mannherz HG, Manstein DJ, Raunser S.

Cell. 2012 Jul 20;150(2):327-38. doi: 10.1016/j.cell.2012.05.037.

50.

Fractional photothermolysis for the treatment of facial wrinkles - searching for optimal treatment parameters in a randomized study in the split-face design.

Peukert N, Bayer J, Becke D, Zurakowski D, Luger T, Manstein D, Laubach HJ.

J Dtsch Dermatol Ges. 2012 Dec;10(12):898-904. doi: 10.1111/j.1610-0387.2012.07986.x. Epub 2012 Jul 9. English, German.

PMID:
22776535

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