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The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness.

Melandri D, Zlatareva I, Chaleil RAG, Dart RJ, Chancellor A, Nussbaumer O, Polyakova O, Roberts NA, Wesch D, Kabelitz D, Irving PM, John S, Mansour S, Bates PA, Vantourout P, Hayday AC.

Nat Immunol. 2018 Nov 12. doi: 10.1038/s41590-018-0253-5. [Epub ahead of print]


A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route.

El-Zaafarany GM, Soliman ME, Mansour S, Cespi M, Palmieri GF, Illum L, Casettari L, Awad GAS.

Pharmaceutics. 2018 Nov 5;10(4). pii: E217. doi: 10.3390/pharmaceutics10040217.


Reliability of deceased donor procurement kidney biopsy images uploaded in United Network for Organ Sharing.

Mansour SG, Hall IE, Reese PP, Jia Y, Thiessen-Philbrook H, Moeckel G, Weng FL, Revelo PM, Khalighi MA, Trivedi A, Doshi MD, Schröppel B, Parikh CR.

Clin Transplant. 2018 Nov 2:e13441. doi: 10.1111/ctr.13441. [Epub ahead of print]


Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.

Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, Knox R, Pittman A, Clark G, Baird W, Bulstrode N, Glover M, Gordon K, Hargrave D, Huson SM, Jacques TS, James G, Kondolf H, Kangesu L, Keppler-Noreuil KM, Khan A, Lindhurst MJ, Lipson M, Mansour S, O'Hara J, Mahon C, Mosica A, Moss C, Murthy A, Ong J, Parker VE, Rivière JB, Sapp JC, Sebire NJ, Shah R, Sivakumar B, Thomas A, Virasami A, Waelchli R, Zeng Z, Biesecker LG, Barnacle A, Topf M, Semple RK, Patton EE, Kinsler VA.

J Clin Invest. 2018 Nov 1;128(11):5185. doi: 10.1172/JCI124649. Epub 2018 Nov 1. No abstract available.


Impact of an invasive strategy in the elderly hospitalized with acute coronary syndrome with emphasis on the nonagenarians.

Couture EL, Farand P, Nguyen M, Allard C, Wells GA, Mansour S, Rinfret S, Afilalo J, Eisenberg M, Montigny M, Kouz S, Afilalo M, Lauzon C, Dery JP, L'Allier P, Schampaert E, Tardif JC, Huynh T.

Catheter Cardiovasc Interv. 2018 Sep 30. doi: 10.1002/ccd.27877. [Epub ahead of print]


A clinical review and introduction of the diagnostic algorithm for thalidomide embryopathy (DATE).

Mansour S, Baple E, Hall CM.

J Hand Surg Eur Vol. 2018 Sep 25:1753193418800631. doi: 10.1177/1753193418800631. [Epub ahead of print]


Ovarian cancer screening-ultrasound; impact on ovarian cancer mortality.

Kamal R, Hamed S, Mansour S, Mounir Y, Abdel Sallam S.

Br J Radiol. 2018 Oct;91(1090):20170571. doi: 10.1259/bjr.20170571. Epub 2018 Sep 4. Review.


A Novel Splice-Site Mutation in VEGFC Is Associated with Congenital Primary Lymphoedema of Gordon.

Nadarajah N, Schulte D, McConnell V, Martin-Almedina S, Karapouliou C, Mortimer PS, Jeffery S, Schulte-Merker S, Gordon K, Mansour S, Ostergaard P.

Int J Mol Sci. 2018 Aug 1;19(8). pii: E2259. doi: 10.3390/ijms19082259.


Canadian Cardiologist Attitudes Regarding Antithrombotic Management of Anterior STEMI Complicated by Apical Dysfunction Without Ventricular Thrombus.

El-Turaby F, Matteau A, Mansour S, Bastiany A, Potter BJ.

Can J Cardiol. 2018 Aug;34(8):1089.e9-1089.e10. doi: 10.1016/j.cjca.2018.04.031. Epub 2018 May 4. No abstract available.


Comparison of Systematic Ticagrelor-Based Dual Antiplatelet Therapy to Selective Triple Antithrombotic Therapy for Left Ventricle Dysfunction Following Anterior STEMI.

Bastiany A, Matteau A, El-Turaby F, Angers-Goulet A, Mansour S, Daneault B, Potter BJ.

Sci Rep. 2018 Jul 9;8(1):10326. doi: 10.1038/s41598-018-28676-4.


Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund's Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB.

Kamel KM, Gad AM, Mansour SM, Safar MM, Fawzy HM.

Inflammation. 2018 Oct;41(5):1974-1986. doi: 10.1007/s10753-018-0841-4.


Isolation and molecular characterization of Frankia strains resistant to some heavy metals.

El Dein Abdel-Lateif KS, Mansour SR, El-Badawy MF, Shohayeb MM.

J Basic Microbiol. 2018 Sep;58(9):720-729. doi: 10.1002/jobm.201800122. Epub 2018 Jul 1.


Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin.

Wolfmeier H, Mansour SC, Liu LT, Pletzer D, Draeger A, Babiychuk EB, Hancock REW.

EBioMedicine. 2018 Jul;33:211-217. doi: 10.1016/j.ebiom.2018.06.016. Epub 2018 Jun 20.


Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens.

Pletzer D, Mansour SC, Hancock REW.

PLoS Pathog. 2018 Jun 21;14(6):e1007084. doi: 10.1371/journal.ppat.1007084. eCollection 2018 Jun.


Longer Inflation Duration and Predilation-Sizing-Postdilation Improve Bioresorbable Scaffold Outcomes in a Long-term All-Comers Canadian Registry.

Haddad K, Tanguay JF, Potter BJ, Matteau A, Gobeil F, Mansour S.

Can J Cardiol. 2018 Jun;34(6):752-758. doi: 10.1016/j.cjca.2018.02.030. Epub 2018 Mar 12.


Seasonal variation in the performance of QuantiFERON-TB Gold In-Tube assays used for the diagnosis of tuberculosis infection.

Tebruegge M, Curtis N, Clifford V, Fernandez-Turienzo C, Klein N, Fidler K, Mansour S, Elkington P, Morris-Jones S.

Tuberculosis (Edinb). 2018 May;110:26-29. doi: 10.1016/ Epub 2018 Mar 8.


Exploring gelatin nanoparticles as novel nanocarriers for Timolol Maleate: Augmented in-vivo efficacy and safe histological profile.

Shokry M, Hathout RM, Mansour S.

Int J Pharm. 2018 Jul 10;545(1-2):229-239. doi: 10.1016/j.ijpharm.2018.04.059. Epub 2018 Apr 27.


Understanding the patient perspective on research access to national health records databases for conduct of randomized registry trials.

Avram R, Marquis-Gravel G, Simard F, Pacheco C, Couture É, Tremblay-Gravel M, Desplantie O, Malhamé I, Bibas L, Mansour S, Parent MC, Farand P, Harvey L, Lessard MG, Ly H, Liu G, Hay AE, Marc Jolicoeur E.

Int J Cardiol. 2018 Jul 1;262:110-116. doi: 10.1016/j.ijcard.2017.12.074.


Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments.

Ecker C, Guo L, Voicu S, Gil-de-Gómez L, Medvec A, Cortina L, Pajda J, Andolina M, Torres-Castillo M, Donato JL, Mansour S, Zynda ER, Lin PY, Varela-Rohena A, Blair IA, Riley JL.

Cell Rep. 2018 Apr 17;23(3):741-755. doi: 10.1016/j.celrep.2018.03.084.


Effect of anticoagulants on admission rates and length of hospital stay for acute venous thromboembolism: A systematic review of randomized control trials.

Hong Y, Mansour S, Alotaibi G, Wu C, McMurtry MS.

Crit Rev Oncol Hematol. 2018 May;125:12-18. doi: 10.1016/j.critrevonc.2018.02.010. Epub 2018 Mar 2. Review.


The impact of contrast-enhanced spectral mammogram (CESM) and three-dimensional breast ultrasound (3DUS) on the characterization of the disease extend in cancer patients.

Helal MH, Mansour SM, Salaleldin LA, Alkalaawy BM, Salem DS, Mokhtar NM.

Br J Radiol. 2018 Jul;91(1087):20170977. doi: 10.1259/bjr.20170977. Epub 2018 May 24.


CT angiography for coronary graft assessment.

Chartrand-Lefebvre C, Stevens LM, Mansour S, Noiseux N.

J Thorac Dis. 2018 Jan;10(1):E77-E78. doi: 10.21037/jtd.2017.11.136. No abstract available.


Rapid prenatal diagnosis using targeted exome sequencing: a cohort study to assess feasibility and potential impact on prenatal counseling and pregnancy management.

Chandler N, Best S, Hayward J, Faravelli F, Mansour S, Kivuva E, Tapon D, Male A, DeVile C, Chitty LS.

Genet Med. 2018 Mar 29. doi: 10.1038/gim.2018.30. [Epub ahead of print]


High Stakes: CTO-PCI in the Post-CABG Patient.

Potter BJ, Matteau A, Noiseux N, Mansour S.

Can J Cardiol. 2018 Mar;34(3):238-240. doi: 10.1016/j.cjca.2017.12.022. Epub 2017 Dec 27. No abstract available.


Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.

Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, Knox R, Pittman A, Clark G, Baird W, Bulstrode N, Glover M, Gordon K, Hargrave D, Huson SM, Jacques TS, James G, Kondolf H, Kangesu L, Keppler-Noreuil KM, Khan A, Lindhurst MJ, Lipson M, Mansour S, O'Hara J, Mahon C, Mosica A, Moss C, Murthy A, Ong J, Parker VE, Rivière JB, Sapp JC, Sebire NJ, Shah R, Sivakumar B, Thomas A, Virasami A, Waelchli R, Zeng Z, Biesecker LG, Barnacle A, Topf M, Semple RK, Patton EE, Kinsler VA.

J Clin Invest. 2018 Apr 2;128(4):1496-1508. doi: 10.1172/JCI98589. Epub 2018 Mar 12.


The versatility of the CD1 lipid antigen presentation pathway.

Chancellor A, Gadola SD, Mansour S.

Immunology. 2018 Jun;154(2):196-203. doi: 10.1111/imm.12912. Epub 2018 Mar 24. Review.


Recurrent Cardiovascular Events in Survivors of Myocardial Infarction With ST-Segment Elevation (from the AMI-QUEBEC Study).

Huynh T, Montigny M, Iftikhar U, Gagnon R, Eisenberg M, Lauzon C, Mansour S, Rinfret S, Afilalo M, Nguyen M, Kouz S, Déry JP, Harvey R, De LaRocheliere R, Cantin B, Schampaert E, Tardif JC.

Am J Cardiol. 2018 Apr 15;121(8):897-902. doi: 10.1016/j.amjcard.2017.12.037. Epub 2018 Jan 31.


Detection and genetic characterization of bovine kobuvirus from calves in Egypt.

Mohamed FF, Mansour SMG, Orabi A, El-Araby IE, Ng TFF, Mor SK, Goyal SM.

Arch Virol. 2018 Jun;163(6):1439-1447. doi: 10.1007/s00705-018-3758-1. Epub 2018 Feb 8.


Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms.

Haney EF, Brito-Sánchez Y, Trimble MJ, Mansour SC, Cherkasov A, Hancock REW.

Sci Rep. 2018 Jan 30;8(1):1871. doi: 10.1038/s41598-018-19669-4.


Human phenotypes caused by PIEZO1 mutations; one gene, two overlapping phenotypes?

Martin-Almedina S, Mansour S, Ostergaard P.

J Physiol. 2018 Mar 15;596(6):985-992. doi: 10.1113/JP275718. Epub 2018 Jan 31.


SHOX haploinsufficiency presenting with isolated short long bones in the second and third trimester.

Ramachandrappa S, Kulkarni A, Gandhi H, Ellis C, Hutt R, Roberts L, Hamid R, Papageorghiou A, Mansour S.

Eur J Hum Genet. 2018 Mar;26(3):350-358. doi: 10.1038/s41431-017-0080-4. Epub 2018 Jan 12.


New Perspectives in Biofilm Eradication.

Wolfmeier H, Pletzer D, Mansour SC, Hancock REW.

ACS Infect Dis. 2018 Feb 9;4(2):93-106. doi: 10.1021/acsinfecdis.7b00170. Epub 2017 Dec 27.


Toxic effect of Moringa peregrina seeds on histological and biochemical analyses of adult male Albino rats.

El-Hak HNG, Moustafa ARA, Mansour SR.

Toxicol Rep. 2017 Nov 12;5:38-45. doi: 10.1016/j.toxrep.2017.12.012. eCollection 2018.


LVT Prophylaxis After Anterior ST-Elevation Myocardial Infarction: A Response to Marquis-Gravel et al.

Bastiany A, Matteau A, Mansour S, Daneault B, Potter BJ.

Can J Cardiol. 2018 Jan;34(1):93.e5. doi: 10.1016/j.cjca.2017.11.015. Epub 2017 Nov 29. No abstract available.


Zinc Ameliorate Oxidative Stress and Hormonal Disturbance Induced by Methomyl, Abamectin, and Their Mixture in Male Rats.

Mansour SA, Abbassy MA, Shaldam HA.

Toxics. 2017 Dec 3;5(4). pii: E37. doi: 10.3390/toxics5040037.


An approach to familial lymphoedema.

Jones GE, Mansour S.

Clin Med (Lond). 2017 Dec;17(6):552-557. doi: 10.7861/clinmedicine.17-6-552. Review.


19p13 microduplications encompassing NFIX are responsible for intellectual disability, short stature and small head circumference.

Trimouille A, Houcinat N, Vuillaume ML, Fergelot P, Boucher C, Toutain J, Caignec CL, Vincent M, Nizon M, Andrieux J, Vanlerberghe C, Delobel B, Duban B, Mansour S, Baple E, McKeown C, Poke G, Robertshaw K, Fifield E, Fabretto A, Pecile V, Gasparini P, Carrozzi M, Lacombe D, Arveiler B, Rooryck C, Moutton S.

Eur J Hum Genet. 2018 Jan;26(1):85-93. doi: 10.1038/s41431-017-0037-7. Epub 2017 Nov 28.


Autologous Bone Marrow Stem Cell Therapy in Patients With ST-Elevation Myocardial Infarction: A Systematic Review and Meta-analysis.

Jeyaraman MM, Rabbani R, Copstein L, Sulaiman W, Farshidfar F, Kashani HH, Qadar SMZ, Guan Q, Skidmore B, Kardami E, Ducas J, Mansour S, Zarychanski R, Abou-Setta AM.

Can J Cardiol. 2017 Dec;33(12):1611-1623. doi: 10.1016/j.cjca.2017.10.001. Epub 2017 Oct 7. Review.


CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains.

Chancellor A, Tocheva AS, Cave-Ayland C, Tezera L, White A, Al Dulayymi JR, Bridgeman JS, Tews I, Wilson S, Lissin NM, Tebruegge M, Marshall B, Sharpe S, Elliott T, Skylaris CK, Essex JW, Baird MS, Gadola S, Elkington P, Mansour S.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10956-E10964. doi: 10.1073/pnas.1708252114. Epub 2017 Nov 20.


PURA syndrome: clinical delineation and genotype-phenotype study in 32 individuals with review of published literature.

Reijnders MRF, Janowski R, Alvi M, Self JE, van Essen TJ, Vreeburg M, Rouhl RPW, Stevens SJC, Stegmann APA, Schieving J, Pfundt R, van Dijk K, Smeets E, Stumpel CTRM, Bok LA, Cobben JM, Engelen M, Mansour S, Whiteford M, Chandler KE, Douzgou S, Cooper NS, Tan EC, Foo R, Lai AHM, Rankin J, Green A, Lönnqvist T, Isohanni P, Williams S, Ruhoy I, Carvalho KS, Dowling JJ, Lev DL, Sterbova K, Lassuthova P, Neupauerová J, Waugh JL, Keros S, Clayton-Smith J, Smithson SF, Brunner HG, van Hoeckel C, Anderson M, Clowes VE, Siu VM, Ddd Study T, Selber P, Leventer RJ, Nellaker C, Niessing D, Hunt D, Baralle D.

J Med Genet. 2018 Feb;55(2):104-113. doi: 10.1136/jmedgenet-2017-104946. Epub 2017 Nov 2.


Bilateral bidirectional Glenn: outcome of off-pump technique.

El Midany AAH, Mostafa EA, Mansour SA, Saffan M, Zalat M, El-Sokkary IN, M E Aletreby A.

Interact Cardiovasc Thorac Surg. 2017 Nov 1;25(5):745-749. doi: 10.1093/icvts/ivx168.


Os Odontoideum: A Comprehensive Clinical and Surgical Review.

Jumah F, Alkhdour S, Mansour S, He P, Hroub A, Adeeb N, Hanif R, Mortazavi MM, Tubbs RS, Nanda A.

Cureus. 2017 Aug 8;9(8):e1551. doi: 10.7759/cureus.1551. Review.


Impact of Paclitaxel-Eluting Balloons Compared to Second-Generation Drug-Eluting Stents for of In-Stent Restenosis in a Primarily Acute Coronary Syndrome Population.

Marquis-Gravel G, Matteau A, Potter BJ, Gobeil F, Noiseux N, Stevens LM, Mansour S.

Arq Bras Cardiol. 2017 Oct;109(4):277-283. doi: 10.5935/abc.20170142. Epub 2017 Sep 28. Portuguese, English.


Examining Insulin Adsorption onto Mesoporous Silica Microparticles for Oral Delivery.

Eilleia SY, Soliman ME, Niedermayer S, Schmidt A, Mansour S, Geneidi AS.

Curr Drug Deliv. 2018;15(4):541-553. doi: 10.2174/1567201814666171002142023.


Permanent Draft Genome sequence for Frankia sp. strain CcI49, a Nitrogen-Fixing Bacterium Isolated from Casuarina cunninghamiana that Infects Elaeagnaceae.

Mansour S, Swanson E, McNutt Z, Pesce C, Harrington K, Abebe-Alele F, Simpson S, Morris K, Thomas WK, Tisa LS.

J Genomics. 2017 Sep 12;5:119-123. doi: 10.7150/jgen.22138. eCollection 2017.


Prevention of Left Ventricular Thrombus Formation and Systemic Embolism After Anterior Myocardial Infarction: A Systematic Literature Review.

Bastiany A, Grenier ME, Matteau A, Mansour S, Daneault B, Potter BJ.

Can J Cardiol. 2017 Oct;33(10):1229-1236. doi: 10.1016/j.cjca.2017.07.479. Epub 2017 Aug 1. Review.


Surface transperineal ultrasound and vaginal abnormalities: applications and strengths.

Hamed ST, Mansour SM.

Br J Radiol. 2017 Dec;90(1080):20170326. doi: 10.1259/bjr.20170326. Epub 2017 Sep 13. Review.


Crystal structure of (E)-furan-2-carbaldehyde O-benzoyloxime.

Hijji YM, Rajan R, Mansour S, Ben Yahia H.

Acta Crystallogr E Crystallogr Commun. 2017 Aug 8;73(Pt 9):1326-1328. doi: 10.1107/S2056989017011562. eCollection 2017 Sep 1.


KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C.

Naiyer MM, Cassidy SA, Magri A, Cowton V, Chen K, Mansour S, Kranidioti H, Mbirbindi B, Rettman P, Harris S, Fanning LJ, Mulder A, Claas FHJ, Davidson AD, Patel AH, Purbhoo MA, Khakoo SI.

Sci Immunol. 2017 Sep 15;2(15). pii: eaal5296. doi: 10.1126/sciimmunol.aal5296.


The Canadian HIV and aging cohort study - determinants of increased risk of cardio-vascular diseases in HIV-infected individuals: rationale and study protocol.

Durand M, Chartrand-Lefebvre C, Baril JG, Trottier S, Trottier B, Harris M, Walmsley S, Conway B, Wong A, Routy JP, Kovacs C, MacPherson PA, Monteith KM, Mansour S, Thanassoulis G, Abrahamowicz M, Zhu Z, Tsoukas C, Ancuta P, Bernard N, Tremblay CL; investigators of the Canadian HIV and Aging Cohort Study.

BMC Infect Dis. 2017 Sep 11;17(1):611. doi: 10.1186/s12879-017-2692-2.

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