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Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant.

DeFilipp Z, Bloom PP, Torres Soto M, Mansour MK, Sater MRA, Huntley MH, Turbett S, Chung RT, Chen YB, Hohmann EL.

N Engl J Med. 2019 Nov 21;381(21):2043-2050. doi: 10.1056/NEJMoa1910437. Epub 2019 Oct 30.


CD82 controls CpG-dependent TLR9 signaling.

Khan NS, Lukason DP, Feliu M, Ward RA, Lord AK, Reedy JL, Ramirez-Ortiz ZG, Tam JM, Kasperkovitz PV, Negoro PE, Vyas TD, Xu S, Brinkmann MM, Acharaya M, Artavanis-Tsakonas K, Frickel EM, Becker CE, Dagher Z, Kim YM, Latz E, Ploegh HL, Mansour MK, Miranti CK, Levitz SM, Vyas JM.

FASEB J. 2019 Nov;33(11):12500-12514. doi: 10.1096/fj.201901547R. Epub 2019 Aug 13.


Anticholinesterase activity and metabolite profiling of Syagrus romanzoffiana (Cham.) Glassman leaves and fruits via UPLC-QTOF-PDA-MS.

El-Hawary SS, Fathy FI, Sleem AA, Morsy FA, Khadar MS, Mansour MK.

Nat Prod Res. 2019 May 31:1-5. doi: 10.1080/14786419.2019.1622113. [Epub ahead of print]


The cost impact of PCT-guided antibiotic stewardship versus usual care for hospitalised patients with suspected sepsis or lower respiratory tract infections in the US: A health economic model analysis.

Mewes JC, Pulia MS, Mansour MK, Broyles MR, Nguyen HB, Steuten LM.

PLoS One. 2019 Apr 23;14(4):e0214222. doi: 10.1371/journal.pone.0214222. eCollection 2019.


Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans.

Tam JM, Reedy JL, Lukason DP, Kuna SG, Acharya M, Khan NS, Negoro PE, Xu S, Ward RA, Feldman MB, Dutko RA, Jeffery JB, Sokolovska A, Wivagg CN, Lassen KG, Le Naour F, Matzaraki V, Garner EC, Xavier RJ, Kumar V, van de Veerdonk FL, Netea MG, Miranti CK, Mansour MK, Vyas JM.

J Immunol. 2019 Jun 1;202(11):3256-3266. doi: 10.4049/jimmunol.1801384. Epub 2019 Apr 22.


Malakoplakia in Thoracic Transplant Recipients.

Lane RJ, Kradin R, Xia D, Buchan CA, Turbett S, Kotton CN, Mansour MK.

Transplant Proc. 2019 Apr;51(3):871-874. doi: 10.1016/j.transproceed.2018.11.008. Epub 2019 Jan 8.


Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation.

Czechowicz A, Palchaudhuri R, Scheck A, Hu Y, Hoggatt J, Saez B, Pang WW, Mansour MK, Tate TA, Chan YY, Walck E, Wernig G, Shizuru JA, Winau F, Scadden DT, Rossi DJ.

Nat Commun. 2019 Feb 6;10(1):617. doi: 10.1038/s41467-018-08201-x.


Frontline Science: Employing enzymatic treatment options for management of ocular biofilm-based infections.

Kugadas A, Geddes-McAlister J, Guy E, DiGiandomenico A, Sykes DB, Mansour MK, Mirchev R, Gadjeva M.

J Leukoc Biol. 2019 Jun;105(6):1099-1110. doi: 10.1002/JLB.4HI0918-364RR. Epub 2019 Jan 28.


Therapeutic drug concentrations of isavuconazole following the administration of isavuconazonium sulfate capsules via gastro-jejunum tube: A case report.

Adamsick ML, Elshaboury RH, Gift T, Mansour MK, Kotton CN, Gandhi RG.

Transpl Infect Dis. 2019 Apr;21(2):e13048. doi: 10.1111/tid.13048. Epub 2019 Jan 29.


Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens.

Mamouei Z, Alqarihi A, Singh S, Xu S, Mansour MK, Ibrahim AS, Uppuluri P.

mSphere. 2018 Oct 31;3(5). pii: e00539-18. doi: 10.1128/mSphere.00539-18.


Biguanides enhance antifungal activity against Candida glabrata.

Xu S, Feliu M, Lord AK, Lukason DP, Negoro PE, Khan NS, Dagher Z, Feldman MB, Reedy JL, Steiger SN, Tam JM, Soukas AA, Sykes DB, Mansour MK.

Virulence. 2018;9(1):1150-1162. doi: 10.1080/21505594.2018.1475798.


The Great Opportunity: Cultivating Scientific Inquiry in Medical Residency.

Vyas JM, Rajagopal J, Sokol CL, Wein MN, Mansour MK, Corey KE, Fishman MC, Armstrong KA.

J Infect Dis. 2018 Aug 14;218(suppl_1):S44-S48. doi: 10.1093/infdis/jiy200.


Fluorescent Tracking of Yeast Division Clarifies the Essential Role of Spleen Tyrosine Kinase in the Intracellular Control of Candida glabrata in Macrophages.

Dagher Z, Xu S, Negoro PE, Khan NS, Feldman MB, Reedy JL, Tam JM, Sykes DB, Mansour MK.

Front Immunol. 2018 May 16;9:1058. doi: 10.3389/fimmu.2018.01058. eCollection 2018.


Cervical Lymphatic Filariasis in a Pediatric Patient: Case Report and Database Analysis of Lymphatic Filariasis in the United States.

Simmonds JC, Mansour MK, Dagher WI.

Am J Trop Med Hyg. 2018 Jul;99(1):104-111. doi: 10.4269/ajtmh.17-0786. Epub 2018 May 24. Review.


An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections.

Fites JS, Gui M, Kernien JF, Negoro P, Dagher Z, Sykes DB, Nett JE, Mansour MK, Klein BS.

PLoS Pathog. 2018 May 21;14(5):e1007073. doi: 10.1371/journal.ppat.1007073. eCollection 2018 May.


It takes a village: Phagocytes play a central role in fungal immunity.

Feldman MB, Vyas JM, Mansour MK.

Semin Cell Dev Biol. 2019 May;89:16-23. doi: 10.1016/j.semcdb.2018.04.008. Epub 2018 Jun 12. Review.


Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity.

DeFilipp Z, Peled JU, Li S, Mahabamunuge J, Dagher Z, Slingerland AE, Del Rio C, Valles B, Kempner ME, Smith M, Brown J, Dey BR, El-Jawahri A, McAfee SL, Spitzer TR, Ballen KK, Sung AD, Dalton TE, Messina JA, Dettmer K, Liebisch G, Oefner P, Taur Y, Pamer EG, Holler E, Mansour MK, van den Brink MRM, Hohmann E, Jenq RR, Chen YB.

Blood Adv. 2018 Apr 10;2(7):745-753. doi: 10.1182/bloodadvances.2018017731.


Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida.

Li SS, Ogbomo H, Mansour MK, Xiang RF, Szabo L, Munro F, Mukherjee P, Mariuzza RA, Amrein M, Vyas JM, Robbins SM, Mody CH.

Nat Commun. 2018 Feb 21;9(1):751. doi: 10.1038/s41467-018-03014-4.


Case 15-2017 - A 27-Year-Old Woman with Anemia, Thrombocytosis, and Skin Lesions after Travel Abroad.

Mansour MK, Letourneau AR, Wallace ZS, Fintelmann FJ, Foreman RK.

N Engl J Med. 2017 May 18;376(20):1973-1981. doi: 10.1056/NEJMcpc1616396. No abstract available.


Serial Procalcitonin as a Predictor of Bacteremia and Need for Intensive Care Unit Care in Adults With Pneumonia, Including Those With Highest Severity: A Prospective Cohort Study.

McCluskey SM, Schuetz P, Abers MS, Bearnot B, Morales ME, Hoffman D, Patel S, Rosario L, Chiappa V, Parry BA, Callahan RT, Bond SA, Lewandrowski K, Binder W, Filbin MR, Vyas JM, Mansour MK.

Open Forum Infect Dis. 2017 Jan 4;4(1):ofw238. doi: 10.1093/ofid/ofw238. eCollection 2017 Winter.


The Carbohydrate Lectin Receptor Dectin-1 Mediates the Immune Response to Exserohilum rostratum.

Reedy JL, Negoro PE, Feliu M, Lord AK, Khan NS, Lukason DP, Wiederhold NP, Tam JM, Mansour MK, Patterson TF, Vyas JM.

Infect Immun. 2017 Feb 23;85(3). pii: e00903-16. doi: 10.1128/IAI.00903-16. Print 2017 Mar.


Personalized medicine. Is it time for infectious diseases?

Al-Mozaini MA, Mansour MK.

Saudi Med J. 2016 Dec;37(12):1309-1311. doi: 10.15537/smj.2016.12.16837.


Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin.

Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT.

Nat Biotechnol. 2016 Jul;34(7):738-45. doi: 10.1038/nbt.3584. Epub 2016 Jun 6.


Editorial Commentary: Fecal ESBL Screening: Are We Ready for This Information?

Turbett SE, Mansour MK.

Clin Infect Dis. 2016 Aug 1;63(3):319-21. doi: 10.1093/cid/ciw288. Epub 2016 May 3. No abstract available.


The Role of Autophagy-Related Proteins in Candida albicans Infections.

Tam JM, Mansour MK, Acharya M, Sokolovska A, Timmons AK, Lacy-Hulbert A, Vyas JM.

Pathogens. 2016 Mar 29;5(2). pii: E34. doi: 10.3390/pathogens5020034. Review.


PKC-δ activation in neutrophils promotes fungal clearance.

Li X, Cullere X, Nishi H, Saggu G, Durand E, Mansour MK, Tam JM, Song XY, Lin X, Vyas JM, Mayadas T.

J Leukoc Biol. 2016 Sep;100(3):581-8. doi: 10.1189/jlb.4A0915-405R. Epub 2016 Mar 10.


Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing β-1,3 Glucan.

Khan NS, Kasperkovitz PV, Timmons AK, Mansour MK, Tam JM, Seward MW, Reedy JL, Puranam S, Feliu M, Vyas JM.

J Immunol. 2016 Mar 1;196(5):2249-61. doi: 10.4049/jimmunol.1401545. Epub 2016 Feb 1.


CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 32-2015. A 57-Year-Old Man with Severe Pneumonia and Hypoxemic Respiratory Failure.

Mansour MK, Ackman JB, Branda JA, Kradin RL.

N Engl J Med. 2015 Oct 15;373(16):1554-64. doi: 10.1056/NEJMcpc1503830. No abstract available.


HIV-Care Outcome in Saudi Arabia; a Longitudinal Cohort.

Al-Mozaini MA, Mansour MK, Al-Hokail AA, Mohmed MA, Daham MA, Al-Abdely HM, Frayha HH, Al-Rabiah FA, Alhajjar SH, Keshavjee S, Adra CN, Alrajhi AA.

J AIDS Clin Res. 2014 Nov 8;5(11). pii: 370.


Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes.

Klassert TE, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Tam JM, Vyas JM, Slevogt H.

Med Microbiol Immunol. 2014 Dec;203(6):415-24. doi: 10.1007/s00430-014-0351-4. Epub 2014 Aug 17. Erratum in: Med Microbiol Immunol. 2014 Dec;203(6):425. Mansour, Michael M [corrected to Mansour, Michael K].


Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages.

Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xavier RJ, Vyas JM.

J Infect Dis. 2014 Dec 1;210(11):1844-54. doi: 10.1093/infdis/jiu290. Epub 2014 May 19.


Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages.

Kasper L, Seider K, Gerwien F, Allert S, Brunke S, Schwarzmüller T, Ames L, Zubiria-Barrera C, Mansour MK, Becken U, Barz D, Vyas JM, Reiling N, Haas A, Haynes K, Kuchler K, Hube B.

PLoS One. 2014 May 1;9(5):e96015. doi: 10.1371/journal.pone.0096015. eCollection 2014.


Macrophage Cryptococcus interactions: an update.

Mansour MK, Reedy JL, Tam JM, Vyas JM.

Curr Fungal Infect Rep. 2014 Mar 1;8(1):109-115.


Dectin-1 activation controls maturation of β-1,3-glucan-containing phagosomes.

Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, Vyas JM.

J Biol Chem. 2013 May 31;288(22):16043-54. doi: 10.1074/jbc.M113.473223. Epub 2013 Apr 22.


Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice.

Grimm MJ, Vethanayagam RR, Almyroudis NG, Dennis CG, Khan AN, D'Auria AC, Singel KL, Davidson BA, Knight PR, Blackwell TS, Hohl TM, Mansour MK, Vyas JM, Röhm M, Urban CF, Kelkka T, Holmdahl R, Segal BH.

J Immunol. 2013 Apr 15;190(8):4175-84. doi: 10.4049/jimmunol.1202800. Epub 2013 Mar 15.


The cell biology of the innate immune response to Aspergillus fumigatus.

Mansour MK, Tam JM, Vyas JM.

Ann N Y Acad Sci. 2012 Dec;1273:78-84. doi: 10.1111/j.1749-6632.2012.06837.x.


Promising new assays and technologies for the diagnosis and management of infectious diseases.

Mitsuma SF, Mansour MK, Dekker JP, Kim J, Rahman MZ, Tweed-Kent A, Schuetz P.

Clin Infect Dis. 2013 Apr;56(7):996-1002. doi: 10.1093/cid/cis1014. Epub 2012 Dec 7. Review.


Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity.

Tam JM, Mansour MK, Khan NS, Yoder NC, Vyas JM.

Integr Biol (Camb). 2012 Feb;4(2):220-7. doi: 10.1039/c2ib00089j. Epub 2011 Dec 23.


Dynamic virulence: real-time assessment of intracellular pathogenesis links Cryptococcus neoformans phenotype with clinical outcome.

Mansour MK, Vyas JM, Levitz SM.

MBio. 2011 Sep 27;2(5). pii: e00217-11. doi: 10.1128/mBio.00217-11. Print 2011.


Toll-like receptor 9 modulates macrophage antifungal effector function during innate recognition of Candida albicans and Saccharomyces cerevisiae.

Kasperkovitz PV, Khan NS, Tam JM, Mansour MK, Davids PJ, Vyas JM.

Infect Immun. 2011 Dec;79(12):4858-67. doi: 10.1128/IAI.05626-11. Epub 2011 Sep 26.


Use of an optical trap for study of host-pathogen interactions for dynamic live cell imaging.

Tam JM, Castro CE, Heath RJ, Mansour MK, Cardenas ML, Xavier RJ, Lang MJ, Vyas JM.

J Vis Exp. 2011 Jul 28;(53). pii: 3123. doi: 10.3791/3123.


The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G Jr, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC Jr, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL Jr, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC 3rd, Olender SA, Ostrowski M, Owen WF Jr, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC 3rd, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM Jr, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M.

Science. 2010 Dec 10;330(6010):1551-7. doi: 10.1126/science.1195271. Epub 2010 Nov 4.


Flow cytometric analysis of the phagocytic cells in active pulmonary tuberculosis.

Gomaa NI, Ahmed AS, El-Hadidy GS, Mansour MK.

Egypt J Immunol. 2004;11(2):133-40.


A model vaccine exploiting fungal mannosylation to increase antigen immunogenicity.

Lam JS, Mansour MK, Specht CA, Levitz SM.

J Immunol. 2005 Dec 1;175(11):7496-503.


Receptor-mediated clearance of Cryptococcus neoformans capsular polysaccharide in vivo.

Yauch LE, Mansour MK, Levitz SM.

Infect Immun. 2005 Dec;73(12):8429-32.


KRE5 gene null mutant strains of Candida albicans are avirulent and have altered cell wall composition and hypha formation properties.

Herrero AB, Magnelli P, Mansour MK, Levitz SM, Bussey H, Abeijon C.

Eukaryot Cell. 2004 Dec;3(6):1423-32.


Protective efficacy of antigenic fractions in mouse models of cryptococcosis.

Mansour MK, Yauch LE, Rottman JB, Levitz SM.

Infect Immun. 2004 Mar;72(3):1746-54.


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