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Items: 1 to 50 of 110

1.

Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival.

Neal CP, Fry AM, Moreman C, McGregor A, Garcea G, Berry DP, Manson MM.

J Surg Oncol. 2014 Dec;110(7):828-38. doi: 10.1002/jso.23717. Epub 2014 Jul 16.

PMID:
25043295
2.

Induction of apoptosis and cell cycle arrest in human colon carcinoma cells by Corema album leaves.

León-González AJ, Manson MM, López-Lizaro M, Navarro I, Martín-Cordero C.

Nat Prod Commun. 2014 Jan;9(1):55-6.

PMID:
24660462
3.

Notch3 and HEY-1 as prognostic biomarkers in pancreatic adenocarcinoma.

Mann CD, Bastianpillai C, Neal CP, Masood MM, Jones DJ, Teichert F, Singh R, Karpova E, Berry DP, Manson MM.

PLoS One. 2012;7(12):e51119. doi: 10.1371/journal.pone.0051119. Epub 2012 Dec 4.

4.

Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage.

Blakemore LM, Boes C, Cordell R, Manson MM.

Carcinogenesis. 2013 Feb;34(2):351-60. doi: 10.1093/carcin/bgs345. Epub 2012 Nov 3.

5.

Inhibition of STAT signalling in bladder cancer by diindolylmethane: relevance to cell adhesion, migration and proliferation.

Sun Y, Cheng MK, Griffiths TR, Mellon JK, Kai B, Kriajevska M, Manson MM.

Curr Cancer Drug Targets. 2013 Jan;13(1):57-68.

PMID:
22920439
6.

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.

Howells LM, Sale S, Sriramareddy SN, Irving GR, Jones DJ, Ottley CJ, Pearson DG, Mann CD, Manson MM, Berry DP, Gescher A, Steward WP, Brown K.

Int J Cancer. 2011 Jul 15;129(2):476-86. doi: 10.1002/ijc.25670. Epub 2010 Nov 3.

7.

Development of a targeted adductomic method for the determination of polycyclic aromatic hydrocarbon DNA adducts using online column-switching liquid chromatography/tandem mass spectrometry.

Singh R, Teichert F, Seidel A, Roach J, Cordell R, Cheng MK, Frank H, Steward WP, Manson MM, Farmer PB.

Rapid Commun Mass Spectrom. 2010 Aug 30;24(16):2329-40. doi: 10.1002/rcm.4645.

PMID:
20658679
8.

Dietary chemopreventive phytochemicals: too little or too much?

Moiseeva EP, Manson MM.

Cancer Prev Res (Phila). 2009 Jul;2(7):611-6. doi: 10.1158/1940-6207.CAPR-08-0102. Review.

9.

Lapatinib, a dual inhibitor of ErbB-1/-2 receptors, enhances effects of combination chemotherapy in bladder cancer cells.

McHugh LA, Sayan AE, Mejlvang J, Griffiths TR, Sun Y, Manson MM, Tulchinsky E, Mellon JK, Kriajevska M.

Int J Oncol. 2009 Apr;34(4):1155-63.

PMID:
19287975
10.

Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis.

Mann CD, Neal CP, Garcea G, Manson MM, Dennison AR, Berry DP.

Eur J Cancer Prev. 2009 Feb;18(1):13-25. doi: 10.1097/CEJ.0b013e3282f0c090. Review.

PMID:
19077560
11.

Prognostic molecular markers in cholangiocarcinoma: a systematic review.

Briggs CD, Neal CP, Mann CD, Steward WP, Manson MM, Berry DP.

Eur J Cancer. 2009 Jan;45(1):33-47. doi: 10.1016/j.ejca.2008.08.024. Epub 2008 Oct 18. Review.

PMID:
18938071
12.

Mechanisms of combined action of different chemopreventive dietary compounds: a review.

de Kok TM, van Breda SG, Manson MM.

Eur J Nutr. 2008 May;47 Suppl 2:51-9. doi: 10.1007/s00394-008-2006-y. Review.

PMID:
18458834
13.

Indole-3-carbinol enhances anti-proliferative, but not anti-invasive effects of oxaliplatin in colorectal cancer cell lines.

Howells LM, Neal CP, Brown MC, Berry DP, Manson MM.

Biochem Pharmacol. 2008 May 1;75(9):1774-82. doi: 10.1016/j.bcp.2008.02.012. Epub 2008 Feb 17.

PMID:
18358454
15.

Determining the efficacy of dietary phytochemicals in cancer prevention.

Manson MM, Foreman BE, Howells LM, Moiseeva EP.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1358-63. Review.

PMID:
17956351
16.
17.

Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.

Howells LM, Moiseeva EP, Neal CP, Foreman BE, Andreadi CK, Sun YY, Hudson EA, Manson MM.

Acta Pharmacol Sin. 2007 Sep;28(9):1274-304. Review.

18.

Glycogen synthase kinase-3 beta; a new target in pancreatic cancer?

Garcea G, Manson MM, Neal CP, Pattenden CJ, Sutton CD, Dennison AR, Berry DP.

Curr Cancer Drug Targets. 2007 May;7(3):209-15. Review.

PMID:
17504118
19.

Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines.

Howells LM, Mitra A, Manson MM.

Int J Cancer. 2007 Jul 1;121(1):175-83.

20.

Prognostic molecular markers in hepatocellular carcinoma: a systematic review.

Mann CD, Neal CP, Garcea G, Manson MM, Dennison AR, Berry DP.

Eur J Cancer. 2007 Apr;43(6):979-92. Epub 2007 Feb 8. Review.

PMID:
17291746
21.

EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells.

Moiseeva EP, Heukers R, Manson MM.

Carcinogenesis. 2007 Feb;28(2):435-45. Epub 2006 Sep 6.

PMID:
16956907
22.

Chemoprevention of pancreatic cancer: a review of the molecular pathways involved, and evidence for the potential for chemoprevention.

Doucas H, Garcea G, Neal CP, Manson MM, Berry DP.

Pancreatology. 2006;6(5):429-39. Epub 2006 Jul 13. Review.

PMID:
16847380
23.

Molecular prognostic markers in resectable colorectal liver metastases: a systematic review.

Neal CP, Garcea G, Doucas H, Manson MM, Sutton CD, Dennison AR, Berry DP.

Eur J Cancer. 2006 Aug;42(12):1728-43. Epub 2006 Jul 3. Review.

PMID:
16815701
24.

Clinical aspects of natural anti-angiogenic drugs.

Neal CP, Berry DP, Doucas H, Manson MM, Steward W, Garcea G.

Curr Drug Targets. 2006 Mar;7(3):371-83. Review.

PMID:
16555420
25.

Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D environment.

Moiseeva EP, Fox LH, Howells LM, Temple LA, Manson MM.

Apoptosis. 2006 May;11(5):799-812.

PMID:
16532375
26.

Ex vivo cancer chemoprevention research possibilities.

Hudson EA, Fox LH, Luckett JC, Manson MM.

Environ Toxicol Pharmacol. 2006 Feb;21(2):204-14. doi: 10.1016/j.etap.2005.07.011. Epub 2005 Aug 30.

PMID:
21783659
27.

Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols.

Andreadi CK, Howells LM, Atherfold PA, Manson MM.

Mol Pharmacol. 2006 Mar;69(3):1033-40. Epub 2005 Dec 14.

PMID:
16354769
29.

Inhibition of survival signalling by dietary polyphenols and indole-3-carbinol.

Manson MM.

Eur J Cancer. 2005 Sep;41(13):1842-53.

PMID:
16087329
30.

Prospects for plant-derived chemopreventive agents exhibiting multiple mechanisms of action.

Howells LM, Manson MM.

Curr Med Chem Anticancer Agents. 2005 May;5(3):201-13. Review.

PMID:
15992350
31.

Inhibition of the respiratory burst by resveratrol in human monocytes: correlation with inhibition of PI3K signaling.

Poolman TM, Ng LL, Farmer PB, Manson MM.

Free Radic Biol Med. 2005 Jul 1;39(1):118-32. Epub 2005 Apr 1.

PMID:
15925284
32.

Changes in the Wnt signalling pathway in gastrointestinal cancers and their prognostic significance.

Doucas H, Garcea G, Neal CP, Manson MM, Berry DP.

Eur J Cancer. 2005 Feb;41(3):365-79. Review.

PMID:
15691635
33.

Innovative agents in cancer prevention.

Manson MM, Farmer PB, Gescher A, Steward WP.

Recent Results Cancer Res. 2005;166:257-75. Review.

PMID:
15648195
34.

Growth-inhibitory and cell cycle-arresting properties of the rice bran constituent tricin in human-derived breast cancer cells in vitro and in nude mice in vivo.

Cai H, Hudson EA, Mann P, Verschoyle RD, Greaves P, Manson MM, Steward WP, Gescher AJ.

Br J Cancer. 2004 Oct 4;91(7):1364-71.

35.

Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma.

Donald S, Verschoyle RD, Greaves P, Colombo T, Zucchetti M, Falcioni C, Zaffaroni M, D'Incalci M, Manson MM, Jimeno J, Steward WP, Gescher AJ.

Int J Cancer. 2004 Oct 10;111(6):961-7.

36.

Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice.

Anderton MJ, Manson MM, Verschoyle RD, Gescher A, Lamb JH, Farmer PB, Steward WP, Williams ML.

Clin Cancer Res. 2004 Aug 1;10(15):5233-41.

37.

Physiological modeling of formulated and crystalline 3,3'-diindolylmethane pharmacokinetics following oral administration in mice.

Anderton MJ, Manson MM, Verschoyle R, Gescher A, Steward WP, Williams ML, Mager DE.

Drug Metab Dispos. 2004 Jun;32(6):632-8.

PMID:
15155555
38.

Liquid chromatographic assay for the simultaneous determination of indole-3-carbinol and its acid condensation products in plasma.

Anderton MJ, Jukes R, Lamb JH, Manson MM, Gescher A, Steward WP, Williams ML.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Apr 25;787(2):281-91.

PMID:
12650751
39.

Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells.

Squires MS, Hudson EA, Howells L, Sale S, Houghton CE, Jones JL, Fox LH, Dickens M, Prigent SA, Manson MM.

Biochem Pharmacol. 2003 Feb 1;65(3):361-76.

PMID:
12527329
40.

Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line.

Hudson EA, Howells LM, Gallacher-Horley B, Fox LH, Gescher A, Manson MM.

BMC Cancer. 2003 Jan 14;3:2. Epub 2003 Jan 14.

41.

Cancer prevention -- the potential for diet to modulate molecular signalling.

Manson MM.

Trends Mol Med. 2003 Jan;9(1):11-8. Review.

PMID:
12524205
42.
43.

Expression of rat aldehyde reductase AKR7A1: influence of age and sex and tissue-specific inducibility.

Grant A, Staffas L, Mancowitz L, Kelly VP, Manson MM, DePierre JW, Hayes JD, Ellis EM.

Biochem Pharmacol. 2001 Dec 1;62(11):1511-9. Erratum in: Biochem Pharmacol 2002 Jul 15;64(2):353. Mancowiz L [corrected to Mancowitz L].

PMID:
11728387
44.

Differences between human breast cell lines in susceptibility towards growth inhibition by genistein.

Dampier K, Hudson EA, Howells LM, Manson MM, Walker RA, Gescher A.

Br J Cancer. 2001 Aug 17;85(4):618-24.

45.

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

Sharma RA, McLelland HR, Hill KA, Ireson CR, Euden SA, Manson MM, Pirmohamed M, Marnett LJ, Gescher AJ, Steward WP.

Clin Cancer Res. 2001 Jul;7(7):1894-900.

46.

Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels.

Sharma RA, Ireson CR, Verschoyle RD, Hill KA, Williams ML, Leuratti C, Manson MM, Marnett LJ, Steward WP, Gescher A.

Clin Cancer Res. 2001 May;7(5):1452-8.

47.

Colorectal cancer chemoprevention: biochemical targets and clinical development of promising agents.

Sharma RA, Manson MM, Gescher A, Steward WP.

Eur J Cancer. 2001 Jan;37(1):12-22. Review.

PMID:
11165125
48.
49.

Modulation of signal-transduction pathways by chemopreventive agents.

Manson MM, Holloway KA, Howells LM, Hudson EA, Plummer SM, Squires MS, Prigent SA.

Biochem Soc Trans. 2000 Feb;28(2):7-12. Review.

PMID:
10816090
50.

Blocking and suppressing mechanisms of chemoprevention by dietary constituents.

Manson MM, Gescher A, Hudson EA, Plummer SM, Squires MS, Prigent SA.

Toxicol Lett. 2000 Mar 15;112-113:499-505. Review.

PMID:
10720772

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