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Items: 8


Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC.

Güttlein LN, Benedetti LG, Fresno C, Spallanzani RG, Mansilla SF, Rotondaro C, Raffo Iraolagoitia XL, Salvatierra E, Bravo AI, Fernández EA, Gottifredi V, Zwirner NW, Llera AS, Podhajcer OL.

Mol Cancer Res. 2017 Mar;15(3):304-316. doi: 10.1158/1541-7786.MCR-16-0243-T. Epub 2016 Dec 28.


Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells.

Mansilla SF, Bertolin AP, Bergoglio V, Pillaire MJ, González Besteiro MA, Luzzani C, Miriuka SG, Cazaux C, Hoffmann JS, Gottifredi V.

Elife. 2016 Oct 14;5. pii: e18020. doi: 10.7554/eLife.18020.


DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.

Hampp S, Kiessling T, Buechle K, Mansilla SF, Thomale J, Rall M, Ahn J, Pospiech H, Gottifredi V, Wiesmüller L.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4311-9. doi: 10.1073/pnas.1605828113. Epub 2016 Jul 12.


Rad51 recombinase prevents Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent DNA after UV irradiation.

Vallerga MB, Mansilla SF, Federico MB, Bertolin AP, Gottifredi V.

Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):E6624-33. doi: 10.1073/pnas.1508543112. Epub 2015 Nov 16.


The identification of translesion DNA synthesis regulators: Inhibitors in the spotlight.

Bertolin AP, Mansilla SF, Gottifredi V.

DNA Repair (Amst). 2015 Aug;32:158-164. doi: 10.1016/j.dnarep.2015.04.027. Epub 2015 May 12. Review.


UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability.

Mansilla SF, Soria G, Vallerga MB, Habif M, Martínez-López W, Prives C, Gottifredi V.

Nucleic Acids Res. 2013 Aug;41(14):6942-51. doi: 10.1093/nar/gkt475. Epub 2013 May 30.


The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers.

Costantino VV, Mansilla SF, Speroni J, Amaya C, Cuello-Carrión D, Ciocca DR, Priestap HA, Barbieri MA, Gottifredi V, Lopez LA.

PLoS One. 2013;8(1):e53168. doi: 10.1371/journal.pone.0053168. Epub 2013 Jan 14.


Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA.

Speroni J, Federico MB, Mansilla SF, Soria G, Gottifredi V.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7344-9. doi: 10.1073/pnas.1116345109. Epub 2012 Apr 23.

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