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Items: 1 to 50 of 70

1.

Collagen reorganization in cartilage under strain probed by polarization sensitive second harmonic generation microscopy.

Mansfield JC, Mandalia V, Toms A, Winlove CP, Brasselet S.

J R Soc Interface. 2019 Jan 31;16(150):20180611. doi: 10.1098/rsif.2018.0611.

2.

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study.

Kennedy NA, Heap GA, Green HD, Hamilton B, Bewshea C, Walker GJ, Thomas A, Nice R, Perry MH, Bouri S, Chanchlani N, Heerasing NM, Hendy P, Lin S, Gaya DR, Cummings JRF, Selinger CP, Lees CW, Hart AL, Parkes M, Sebastian S, Mansfield JC, Irving PM, Lindsay J, Russell RK, McDonald TJ, McGovern D, Goodhand JR, Ahmad T; UK Inflammatory Bowel Disease Pharmacogenetics Study Group.

Lancet Gastroenterol Hepatol. 2019 May;4(5):341-353. doi: 10.1016/S2468-1253(19)30012-3. Epub 2019 Feb 27.

PMID:
30824404
3.

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.

Walker GJ, Harrison JW, Heap GA, Voskuil MD, Andersen V, Anderson CA, Ananthakrishnan AN, Barrett JC, Beaugerie L, Bewshea CM, Cole AT, Cummings FR, Daly MJ, Ellul P, Fedorak RN, Festen EAM, Florin TH, Gaya DR, Halfvarson J, Hart AL, Heerasing NM, Hendy P, Irving PM, Jones SE, Koskela J, Lindsay JO, Mansfield JC, McGovern D, Parkes M, Pollok RCG, Ramakrishnan S, Rampton DS, Rivas MA, Russell RK, Schultz M, Sebastian S, Seksik P, Singh A, So K, Sokol H, Subramaniam K, Todd A, Annese V, Weersma RK, Xavier R, Ward R, Weedon MN, Goodhand JR, Kennedy NA, Ahmad T; IBD Pharmacogenetics Study Group.

JAMA. 2019 Feb 26;321(8):773-785. doi: 10.1001/jama.2019.0709. Erratum in: JAMA. 2019 Apr 23;321(16):1636.

PMID:
30806694
4.

The importance of molecular immune investigation in therapeutic clinical development for biomarker assessment.

Lamb CA, Mansfield JC, Kirby JA, Keir ME.

J Crohns Colitis. 2018 Dec 28. doi: 10.1093/ecco-jcc/jjy219. [Epub ahead of print] No abstract available.

PMID:
30596983
5.

AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation.

Ichikawa R, Lamb CA, Eastham-Anderson J, Scherl A, Raffals L, Faubion WA, Bennett MR, Long AK, Mansfield JC, Kirby JA, Keir ME.

J Crohns Colitis. 2018 Nov 9;12(10):1191-1199. doi: 10.1093/ecco-jcc/jjy084.

6.

Subwavelength hyperspectral THz studies of articular cartilage.

Stantchev RI, Mansfield JC, Edginton RS, Hobson P, Palombo F, Hendry E.

Sci Rep. 2018 May 2;8(1):6924. doi: 10.1038/s41598-018-25057-9.

7.

Can faecal calprotectin predict relapse in inflammatory bowel disease: a mini review.

Chew TS, Mansfield JC.

Frontline Gastroenterol. 2018 Jan;9(1):23-28. doi: 10.1136/flgastro-2016-100686. Epub 2016 Apr 5. Review.

8.

Exome Sequencing and Genotyping Identify a Rare Variant in NLRP7 Gene Associated With Ulcerative Colitis.

Onoufriadis A, Stone K, Katsiamides A, Amar A, Omar Y, de Lange KM, Taylor K, Barrett JC, Pollok R, Hayee B, Mansfield JC, Sanderson JD, Simpson MA, Mathew CG, Prescott NJ.

J Crohns Colitis. 2018 Feb 28;12(3):321-326. doi: 10.1093/ecco-jcc/jjx157.

9.

T Lymphocytes Expressing AlphaE Beta7 Integrin in Ulcerative Colitis: Associations With Cellular Lineage and Phenotype.

Lamb CA, Kirby JA, Keir ME, Mansfield JC.

J Crohns Colitis. 2017 Dec 4;11(12):1504-1505. doi: 10.1093/ecco-jcc/jjx097. No abstract available.

10.

The effects of needle damage on annulus fibrosus micromechanics.

Vergari C, Mansfield JC, Chan D, Clarke A, Meakin JR, Winlove PC.

Acta Biomater. 2017 Nov;63:274-282. doi: 10.1016/j.actbio.2017.09.015. Epub 2017 Sep 14.

PMID:
28917706
11.

Editorial: how effective is vedolizumab in the 'real world'?

Speight RA, Mansfield JC.

Aliment Pharmacol Ther. 2017 Sep;46(5):555-556. doi: 10.1111/apt.14215. No abstract available.

12.

Lipid distribution, composition and uptake in bovine articular cartilage studied using Raman micro-spectrometry and confocal microscopy.

Mansfield JC, Winlove CP.

J Anat. 2017 Jul;231(1):156-166. doi: 10.1111/joa.12624. Epub 2017 May 16.

13.

αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis.

Lamb CA, Mansfield JC, Tew GW, Gibbons D, Long AK, Irving P, Diehl L, Eastham-Anderson J, Price MB, O'Boyle G, Jones DEJ, O'Byrne S, Hayday A, Keir ME, Egen JG, Kirby JA.

J Crohns Colitis. 2017 May 1;11(5):610-620. doi: 10.1093/ecco-jcc/jjw189.

14.

Bovine and degenerated human annulus fibrosus: a microstructural and micromechanical comparison.

Vergari C, Chan D, Clarke A, Mansfield JC, Meakin JR, Winlove PC.

Biomech Model Mechanobiol. 2017 Aug;16(4):1475-1484. doi: 10.1007/s10237-017-0900-z. Epub 2017 Apr 4.

15.

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.

Lee JC, Biasci D, Roberts R, Gearry RB, Mansfield JC, Ahmad T, Prescott NJ, Satsangi J, Wilson DC, Jostins L, Anderson CA; UK IBD Genetics Consortium, Traherne JA, Lyons PA, Parkes M, Smith KG.

Nat Genet. 2017 Feb;49(2):262-268. doi: 10.1038/ng.3755. Epub 2017 Jan 9.

16.

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.

Luo Y, de Lange KM, Jostins L, Moutsianas L, Randall J, Kennedy NA, Lamb CA, McCarthy S, Ahmad T, Edwards C, Serra EG, Hart A, Hawkey C, Mansfield JC, Mowat C, Newman WG, Nichols S, Pollard M, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson DC, Lee JC, Prescott NJ, Lees CW, Mathew CG, Parkes M, Barrett JC, Anderson CA.

Nat Genet. 2017 Feb;49(2):186-192. doi: 10.1038/ng.3761. Epub 2017 Jan 9.

17.

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

de Lange KM, Moutsianas L, Lee JC, Lamb CA, Luo Y, Kennedy NA, Jostins L, Rice DL, Gutierrez-Achury J, Ji SG, Heap G, Nimmo ER, Edwards C, Henderson P, Mowat C, Sanderson J, Satsangi J, Simmons A, Wilson DC, Tremelling M, Hart A, Mathew CG, Newman WG, Parkes M, Lees CW, Uhlig H, Hawkey C, Prescott NJ, Ahmad T, Mansfield JC, Anderson CA, Barrett JC.

Nat Genet. 2017 Feb;49(2):256-261. doi: 10.1038/ng.3760. Epub 2017 Jan 9.

18.

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis.

Tew GW, Hackney JA, Gibbons D, Lamb CA, Luca D, Egen JG, Diehl L, Eastham Anderson J, Vermeire S, Mansfield JC, Feagan BG, Panes J, Baumgart DC, Schreiber S, Dotan I, Sandborn WJ, Kirby JA, Irving PM, De Hertogh G, Van Assche GA, Rutgeerts P, O'Byrne S, Hayday A, Keir ME.

Gastroenterology. 2016 Feb;150(2):477-87.e9. doi: 10.1053/j.gastro.2015.10.041. Epub 2015 Oct 30.

19.

The micromechanics of the superficial zone of articular cartilage.

Mansfield JC, Bell JS, Winlove CP.

Osteoarthritis Cartilage. 2015 Oct;23(10):1806-16. doi: 10.1016/j.joca.2015.05.030. Epub 2015 Jun 5.

20.

In vivo chemical and structural analysis of plant cuticular waxes using stimulated Raman scattering microscopy.

Littlejohn GR, Mansfield JC, Parker D, Lind R, Perfect S, Seymour M, Smirnoff N, Love J, Moger J.

Plant Physiol. 2015 May;168(1):18-28. doi: 10.1104/pp.15.00119. Epub 2015 Mar 17.

21.

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.

Prescott NJ, Lehne B, Stone K, Lee JC, Taylor K, Knight J, Papouli E, Mirza MM, Simpson MA, Spain SL, Lu G, Fraternali F, Bumpstead SJ, Gray E, Amar A, Bye H, Green P, Chung-Faye G, Hayee B, Pollok R, Satsangi J, Parkes M, Barrett JC, Mansfield JC, Sanderson J, Lewis CM, Weale ME, Schlitt T, Mathew CG; UK IBD Genetics Consortium.

PLoS Genet. 2015 Feb 11;11(2):e1004955. doi: 10.1371/journal.pgen.1004955. eCollection 2015 Feb. Erratum in: PLoS Genet. 2015 Apr;11(4):e1005172.

22.

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial.

Vermeire S, O'Byrne S, Keir M, Williams M, Lu TT, Mansfield JC, Lamb CA, Feagan BG, Panes J, Salas A, Baumgart DC, Schreiber S, Dotan I, Sandborn WJ, Tew GW, Luca D, Tang MT, Diehl L, Eastham-Anderson J, De Hertogh G, Perrier C, Egen JG, Kirby JA, van Assche G, Rutgeerts P.

Lancet. 2014 Jul 26;384(9940):309-18. doi: 10.1016/S0140-6736(14)60661-9. Epub 2014 May 9.

23.

An update: improvements in imaging perfluorocarbon-mounted plant leaves with implications for studies of plant pathology, physiology, development and cell biology.

Littlejohn GR, Mansfield JC, Christmas JT, Witterick E, Fricker MD, Grant MR, Smirnoff N, Everson RM, Moger J, Love J.

Front Plant Sci. 2014 Apr 23;5:140. doi: 10.3389/fpls.2014.00140. eCollection 2014.

24.

The structure and micromechanics of elastic tissue.

Green EM, Mansfield JC, Bell JS, Winlove CP.

Interface Focus. 2014 Apr 6;4(2):20130058. doi: 10.1098/rsfs.2013.0058. Review.

25.

Micromechanical response of articular cartilage to tensile load measured using nonlinear microscopy.

Bell JS, Christmas J, Mansfield JC, Everson RM, Winlove CP.

Acta Biomater. 2014 Jun;10(6):2574-81. doi: 10.1016/j.actbio.2014.02.008. Epub 2014 Feb 11.

PMID:
24525036
26.

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.

Lee JC, Espéli M, Anderson CA, Linterman MA, Pocock JM, Williams NJ, Roberts R, Viatte S, Fu B, Peshu N, Hien TT, Phu NH, Wesley E, Edwards C, Ahmad T, Mansfield JC, Gearry R, Dunstan S, Williams TN, Barton A, Vinuesa CG; UK IBD Genetics Consortium, Parkes M, Lyons PA, Smith KG.

Cell. 2013 Sep 26;155(1):57-69. doi: 10.1016/j.cell.2013.08.034. Epub 2013 Sep 12.

27.

Sexually transmitted infections manifesting as proctitis.

Lamb CA, Lamb EI, Mansfield JC, Sankar KN.

Frontline Gastroenterol. 2013 Jan;4(1):32-40.

28.

Drug advances in inflammatory bowel disease.

Speight RA, Mansfield JC.

Clin Med (Lond). 2013 Aug;13(4):378-82. doi: 10.7861/clinmedicine.13-4-378. Review.

29.

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability.

Hunt KA, Mistry V, Bockett NA, Ahmad T, Ban M, Barker JN, Barrett JC, Blackburn H, Brand O, Burren O, Capon F, Compston A, Gough SC, Jostins L, Kong Y, Lee JC, Lek M, MacArthur DG, Mansfield JC, Mathew CG, Mein CA, Mirza M, Nutland S, Onengut-Gumuscu S, Papouli E, Parkes M, Rich SS, Sawcer S, Satsangi J, Simmonds MJ, Trembath RC, Walker NM, Wozniak E, Todd JA, Simpson MA, Plagnol V, van Heel DA.

Nature. 2013 Jun 13;498(7453):232-5. doi: 10.1038/nature12170. Epub 2013 May 22.

30.

Label-free chemically specific imaging in planta with stimulated Raman scattering microscopy.

Mansfield JC, Littlejohn GR, Seymour MP, Lind RJ, Perfect S, Moger J.

Anal Chem. 2013 May 21;85(10):5055-63. doi: 10.1021/ac400266a. Epub 2013 Apr 30.

PMID:
23581493
31.

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis.

Rutgeerts PJ, Fedorak RN, Hommes DW, Sturm A, Baumgart DC, Bressler B, Schreiber S, Mansfield JC, Williams M, Tang M, Visich J, Wei X, Keir M, Luca D, Danilenko D, Egen J, O'Byrne S.

Gut. 2013 Aug;62(8):1122-30. doi: 10.1136/gutjnl-2011-301769. Epub 2012 Jun 20.

32.

A multi-modal multiphoton investigation of microstructure in the deep zone and calcified cartilage.

Mansfield JC, Winlove CP.

J Anat. 2012 Apr;220(4):405-16. doi: 10.1111/j.1469-7580.2012.01479.x. Epub 2012 Feb 14.

33.

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C, Ellinghaus D, Fehrmann RS, Floyd JA, Florin T, Franchimont D, Franke L, Georges M, Glas J, Glazer NL, Guthery SL, Haritunians T, Hayward NK, Hugot JP, Jobin G, Laukens D, Lawrance I, Lémann M, Levine A, Libioulle C, Louis E, McGovern DP, Milla M, Montgomery GW, Morley KI, Mowat C, Ng A, Newman W, Ophoff RA, Papi L, Palmieri O, Peyrin-Biroulet L, Panés J, Phillips A, Prescott NJ, Proctor DD, Roberts R, Russell R, Rutgeerts P, Sanderson J, Sans M, Schumm P, Seibold F, Sharma Y, Simms LA, Seielstad M, Steinhart AH, Targan SR, van den Berg LH, Vatn M, Verspaget H, Walters T, Wijmenga C, Wilson DC, Westra HJ, Xavier RJ, Zhao ZZ, Ponsioen CY, Andersen V, Torkvist L, Gazouli M, Anagnou NP, Karlsen TH, Kupcinskas L, Sventoraityte J, Mansfield JC, Kugathasan S, Silverberg MS, Halfvarson J, Rotter JI, Mathew CG, Griffiths AM, Gearry R, Ahmad T, Brant SR, Chamaillard M, Satsangi J, Cho JH, Schreiber S, Daly MJ, Barrett JC, Parkes M, Annese V, Hakonarson H, Radford-Smith G, Duerr RH, Vermeire S, Weersma RK, Rioux JD.

Nat Genet. 2011 Mar;43(3):246-52. doi: 10.1038/ng.764. Epub 2011 Feb 6. Erratum in: Nat Genet. 2011 Sep;43(9):919.

34.

Measurement of faecal calprotectin and lactoferrin in inflammatory bowel disease.

Lamb CA, Mansfield JC.

Frontline Gastroenterol. 2011 Jan;2(1):13-18. Epub 2010 Nov 3.

35.

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew CG, Montgomery GW, Prescott NJ, Raychaudhuri S, Rotter JI, Schumm P, Sharma Y, Simms LA, Taylor KD, Whiteman D, Wijmenga C, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Cohen A, Colombel JF, Cottone M, Stronati L, Denson T, De Vos M, D'Inca R, Dubinsky M, Edwards C, Florin T, Franchimont D, Gearry R, Glas J, Van Gossum A, Guthery SL, Halfvarson J, Verspaget HW, Hugot JP, Karban A, Laukens D, Lawrance I, Lemann M, Levine A, Libioulle C, Louis E, Mowat C, Newman W, Panés J, Phillips A, Proctor DD, Regueiro M, Russell R, Rutgeerts P, Sanderson J, Sans M, Seibold F, Steinhart AH, Stokkers PC, Torkvist L, Kullak-Ublick G, Wilson D, Walters T, Targan SR, Brant SR, Rioux JD, D'Amato M, Weersma RK, Kugathasan S, Griffiths AM, Mansfield JC, Vermeire S, Duerr RH, Silverberg MS, Satsangi J, Schreiber S, Cho JH, Annese V, Hakonarson H, Daly MJ, Parkes M.

Nat Genet. 2010 Dec;42(12):1118-25. doi: 10.1038/ng.717.

36.

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

Aldhous MC, Abu Bakar S, Prescott NJ, Palla R, Soo K, Mansfield JC, Mathew CG, Satsangi J, Armour JA.

Hum Mol Genet. 2010 Dec 15;19(24):4930-8. doi: 10.1093/hmg/ddq411. Epub 2010 Sep 21.

37.

Management of Crohn's disease.

Lamb CA, Speight RA, Needham S, Graham JY, Mansfield JC.

Gut. 2010 Mar;59(3):340. doi: 10.1136/gut.2010.208637. No abstract available.

PMID:
20207639
38.

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.

Prescott NJ, Dominy KM, Kubo M, Lewis CM, Fisher SA, Redon R, Huang N, Stranger BE, Blaszczyk K, Hudspith B, Parkes G, Hosono N, Yamazaki K, Onnie CM, Forbes A, Dermitzakis ET, Nakamura Y, Mansfield JC, Sanderson J, Hurles ME, Roberts RG, Mathew CG.

Hum Mol Genet. 2010 May 1;19(9):1828-39. doi: 10.1093/hmg/ddq041. Epub 2010 Jan 27.

39.

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

UK IBD Genetics Consortium, Barrett JC, Lee JC, Lees CW, Prescott NJ, Anderson CA, Phillips A, Wesley E, Parnell K, Zhang H, Drummond H, Nimmo ER, Massey D, Blaszczyk K, Elliott T, Cotterill L, Dallal H, Lobo AJ, Mowat C, Sanderson JD, Jewell DP, Newman WG, Edwards C, Ahmad T, Mansfield JC, Satsangi J, Parkes M, Mathew CG; Wellcome Trust Case Control Consortium 2, Donnelly P, Peltonen L, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Craddock N, Deloukas P, Duncanson A, Jankowski J, Markus HS, Mathew CG, McCarthy MI, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Samani N, Trembath RC, Viswanathan AC, Wood N, Spencer CC, Barrett JC, Bellenguez C, Davison D, Freeman C, Strange A, Donnelly P, Langford C, Hunt SE, Edkins S, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Gray E, Hammond N, Jayakumar A, McCann OT, Liddle J, Perez ML, Potter SC, Ravindrarajah R, Ricketts M, Waller M, Weston P, Widaa S, Whittaker P, Deloukas P, Peltonen L, Mathew CG, Blackwell JM, Brown MA, Corvin A, McCarthy MI, Spencer CC, Attwood AP, Stephens J, Sambrook J, Ouwehand WH, McArdle WL, Ring SM, Strachan DP.

Nat Genet. 2009 Dec;41(12):1330-4. doi: 10.1038/ng.483. Epub 2009 Nov 15.

40.

Safety of bisphosphonates in women of child bearing age.

McKenna M, Mansfield JC.

Aliment Pharmacol Ther. 2009 Jun 1;29(11):1214-5; author reply 1215-6. doi: 10.1111/j.1365-2036.2009.03985.x. No abstract available.

41.

Anti-tissue transglutaminase antibodies in the follow-up of adult coeliac disease.

Dipper CR, Maitra S, Thomas R, Lamb CA, McLean-Tooke AP, Ward R, Smith D, Spickett G, Mansfield JC.

Aliment Pharmacol Ther. 2009 Aug;30(3):236-44. doi: 10.1111/j.1365-2036.2009.04039.x. Epub 2009 May 12.

42.

Faecal calprotectin or lactoferrin can identify postoperative recurrence in Crohn's disease.

Lamb CA, Mohiuddin MK, Gicquel J, Neely D, Bergin FG, Hanson JM, Mansfield JC.

Br J Surg. 2009 Jun;96(6):663-74. doi: 10.1002/bjs.6593.

PMID:
19384912
43.

Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease.

Chapman JM, Onnie CM, Prescott NJ, Fisher SA, Mansfield JC, Mathew CG, Lewis CM, Verzilli CJ, Whittaker JC.

Am J Hum Genet. 2009 Feb;84(2):178-87. doi: 10.1016/j.ajhg.2008.12.015. Epub 2009 Jan 29.

44.

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.

Anderson CA, Massey DC, Barrett JC, Prescott NJ, Tremelling M, Fisher SA, Gwilliam R, Jacob J, Nimmo ER, Drummond H, Lees CW, Onnie CM, Hanson C, Blaszczyk K, Ravindrarajah R, Hunt S, Varma D, Hammond N, Lewis G, Attlesey H, Watkins N, Ouwehand W, Strachan D, McArdle W, Lewis CM; Wellcome Trust Case Control Consortium, Lobo A, Sanderson J, Jewell DP, Deloukas P, Mansfield JC, Mathew CG, Satsangi J, Parkes M.

Gastroenterology. 2009 Feb;136(2):523-9.e3. doi: 10.1053/j.gastro.2008.10.032. Epub 2008 Oct 25.

45.

Collagen fiber arrangement in normal and diseased cartilage studied by polarization sensitive nonlinear microscopy.

Mansfield JC, Winlove CP, Moger J, Matcher SJ.

J Biomed Opt. 2008 Jul-Aug;13(4):044020. doi: 10.1117/1.2950318.

PMID:
19021348
46.

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.

Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, Prescott NJ, Nimmo ER, Massey D, Berzuini C, Johnson C, Barrett JC, Cummings FR, Drummond H, Lees CW, Onnie CM, Hanson CE, Blaszczyk K, Inouye M, Ewels P, Ravindrarajah R, Keniry A, Hunt S, Carter M, Watkins N, Ouwehand W, Lewis CM, Cardon L; Wellcome Trust Case Control Consortium, Lobo A, Forbes A, Sanderson J, Jewell DP, Mansfield JC, Deloukas P, Mathew CG, Parkes M, Satsangi J.

Nat Genet. 2008 Jun;40(6):710-2. doi: 10.1038/ng.145. Epub 2008 Apr 27.

47.

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Wellcome Trust Case Control Consortium; Australo-Anglo-American Spondylitis Consortium (TASC), Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donnelly P, Barrett JC, Davison D, Easton D, Evans DM, Leung HT, Marchini JL, Morris AP, Spencer CC, Tobin MD, Attwood AP, Boorman JP, Cant B, Everson U, Hussey JM, Jolley JD, Knight AS, Koch K, Meech E, Nutland S, Prowse CV, Stevens HE, Taylor NC, Walters GR, Walker NM, Watkins NA, Winzer T, Jones RW, McArdle WL, Ring SM, Strachan DP, Pembrey M, Breen G, St Clair D, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green EK, Grozeva D, Hamshere ML, Holmans PA, Jones IR, Kirov G, Moskivina V, Nikolov I, O'Donovan MC, Owen MJ, Collier DA, Elkin A, Farmer A, Williamson R, McGuffin P, Young AH, Ferrier IN, Ball SG, Balmforth AJ, Barrett JH, Bishop TD, Iles MM, Maqbool A, Yuldasheva N, Hall AS, Braund PS, Dixon RJ, Mangino M, Stevens S, Thompson JR, Bredin F, Tremelling M, Parkes M, Drummond H, Lees CW, Nimmo ER, Satsangi J, Fisher SA, Forbes A, Lewis CM, Onnie CM, Prescott NJ, Sanderson J, Matthew CG, Barbour J, Mohiuddin MK, Todhunter CE, Mansfield JC, Ahmad T, Cummings FR, Jewell DP, Webster J, Brown MJ, Lathrop MG, Connell J, Dominiczak A, Marcano CA, Burke B, Dobson R, Gungadoo J, Lee KL, Munroe PB, Newhouse SJ, Onipinla A, Wallace C, Xue M, Caulfield M, Farrall M, Barton A; Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee, Bruce IN, Donovan H, Eyre S, Gilbert PD, Hilder SL, Hinks AM, John SL, Potter C, Silman AJ, Symmons DP, Thomson W, Worthington J, Dunger DB, Widmer B, Frayling TM, Freathy RM, Lango H, Perry JR, Shields BM, Weedon MN, Hattersley AT, Hitman GA, Walker M, Elliott KS, Groves CJ, Lindgren CM, Rayner NW, Timpson NJ, Zeggini E, Newport M, Sirugo G, Lyons E, Vannberg F, Hill AV, Bradbury LA, Farrar C, Pointon JJ, Wordsworth P, Brown MA, Franklyn JA, Heward JM, Simmonds MJ, Gough SC, Seal S; Breast Cancer Susceptibility Collaboration (UK), Stratton MR, Rahman N, Ban M, Goris A, Sawcer SJ, Compston A, Conway D, Jallow M, Newport M, Sirugo G, Rockett KA, Bumpstead SJ, Chaney A, Downes K, Ghori MJ, Gwilliam R, Hunt SE, Inouye M, Keniry A, King E, McGinnis R, Potter S, Ravindrarajah R, Whittaker P, Widden C, Withers D, Cardin NJ, Davison D, Ferreira T, Pereira-Gale J, Hallgrimsdo'ttir IB, Howie BN, Su Z, Teo YY, Vukcevic D, Bentley D, Brown MA, Compston A, Farrall M, Hall AS, Hattersley AT, Hill AV, Parkes M, Pembrey M, Stratton MR, Mitchell SL, Newby PR, Brand OJ, Carr-Smith J, Pearce SH, McGinnis R, Keniry A, Deloukas P, Reveille JD, Zhou X, Sims AM, Dowling A, Taylor J, Doan T, Davis JC, Savage L, Ward MM, Learch TL, Weisman MH, Brown M.

Nat Genet. 2007 Nov;39(11):1329-37. Epub 2007 Oct 21.

48.

A randomized, double-blind, placebo-controlled trial of lenalidomide in the treatment of moderately severe active Crohn's disease.

Mansfield JC, Parkes M, Hawthorne AB, Forbes A, Probert CS, Perowne RC, Cooper A, Zeldis JB, Manning DC, Hawkey CJ.

Aliment Pharmacol Ther. 2007 Aug 1;26(3):421-30.

49.

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PMID:
17484864

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