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Items: 1 to 50 of 70

1.

An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules.

Bakos G, Yu L, Gak IA, Roumeliotis TI, Liakopoulos D, Choudhary JS, Mansfeld J.

Nat Commun. 2018 Nov 14;9(1):4776. doi: 10.1038/s41467-018-07251-5.

2.

Conditional control of fluorescent protein degradation by an auxin-dependent nanobody.

Daniel K, Icha J, Horenburg C, Müller D, Norden C, Mansfeld J.

Nat Commun. 2018 Aug 17;9(1):3297. doi: 10.1038/s41467-018-05855-5.

3.

Constitutive regulation of mitochondrial morphology by Aurora A kinase depends on a predicted cryptic targeting sequence at the N-terminus.

Grant R, Abdelbaki A, Bertoldi A, Gavilan MP, Mansfeld J, Glover DM, Lindon C.

Open Biol. 2018 Jun;8(6). pii: 170272. doi: 10.1098/rsob.170272.

4.

Distinct Levels of Reactive Oxygen Species Coordinate Metabolic Activity with Beta-cell Mass Plasticity.

Ahmed Alfar E, Kirova D, Konantz J, Birke S, Mansfeld J, Ninov N.

Sci Rep. 2017 Jun 26;7(1):3994. doi: 10.1038/s41598-017-03873-9.

5.

PLK1 Activation in Late G2 Sets Up Commitment to Mitosis.

Gheghiani L, Loew D, Lombard B, Mansfeld J, Gavet O.

Cell Rep. 2017 Jun 6;19(10):2060-2073. doi: 10.1016/j.celrep.2017.05.031.

6.

Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification.

Zerjatke T, Gak IA, Kirova D, Fuhrmann M, Daniel K, Gonciarz M, Müller D, Glauche I, Mansfeld J.

Cell Rep. 2017 May 30;19(9):1953-1966. doi: 10.1016/j.celrep.2017.05.022.

7.

DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression.

Barr AR, Cooper S, Heldt FS, Butera F, Stoy H, Mansfeld J, Novák B, Bakal C.

Nat Commun. 2017 Mar 20;8:14728. doi: 10.1038/ncomms14728.

8.

Metal ions and phosphatidylinositol 4,5-bisphosphate as interacting effectors of α-type plant phospholipase D.

Dreßler L, Michel F, Thondorf I, Mansfeld J, Golbik R, Ulbrich-Hofmann R.

Phytochemistry. 2017 Jun;138:57-64. doi: 10.1016/j.phytochem.2017.02.024. Epub 2017 Mar 7.

PMID:
28283189
9.

Identification of a secretory phospholipase A2 from Papaver somniferum L. that transforms membrane phospholipids.

Jablonická V, Mansfeld J, Heilmann I, Obložinský M, Heilmann M.

Phytochemistry. 2016 Sep;129:4-13. doi: 10.1016/j.phytochem.2016.07.010. Epub 2016 Jul 26.

PMID:
27473012
10.

A Genome-Scale Database and Reconstruction of Caenorhabditis elegans Metabolism.

Gebauer J, Gentsch C, Mansfeld J, Schmeißer K, Waschina S, Brandes S, Klimmasch L, Zamboni N, Zarse K, Schuster S, Ristow M, Schäuble S, Kaleta C.

Cell Syst. 2016 May 25;2(5):312-22. doi: 10.1016/j.cels.2016.04.017. Epub 2016 May 19.

11.

Retraction Notice to: The Anaphase-Promoting Complex/Cyclosome Is Essential for Entry into Meiotic M-Phase.

Malhotra S, Vinod PK, Mansfeld J, Stemmann O, Mayer TU.

Dev Cell. 2016 May 9;37(3):289. doi: 10.1016/j.devcel.2016.04.013. No abstract available.

12.

RETRACTED: The Anaphase-Promoting Complex/Cyclosome Is Essential for Entry into Meiotic M-Phase.

Malhotra S, Vinod PK, Mansfeld J, Stemmann O, Mayer TU.

Dev Cell. 2016 Jan 11;36(1):94-102. doi: 10.1016/j.devcel.2015.12.009. Retraction in: Dev Cell. 2016 May 9;37(3):289.

13.

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.

Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M.

Nat Commun. 2015 Dec 1;6:10043. doi: 10.1038/ncomms10043.

14.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M.

Cell. 2015 Oct 22;163(3):712-23. doi: 10.1016/j.cell.2015.09.053. Epub 2015 Oct 22.

15.

Purification, sequencing and characterization of phospholipase D from Indian mustard seeds.

Khatoon H, Mansfeld J, Schierhorn A, Ulbrich-Hofmann R.

Phytochemistry. 2015 Sep;117:65-75. doi: 10.1016/j.phytochem.2015.05.022. Epub 2015 Jun 7.

PMID:
26057230
16.

The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators.

Di Fiore B, Davey NE, Hagting A, Izawa D, Mansfeld J, Gibson TJ, Pines J.

Dev Cell. 2015 Feb 9;32(3):358-372. doi: 10.1016/j.devcel.2015.01.003.

17.

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping.

Otto O, Rosendahl P, Mietke A, Golfier S, Herold C, Klaue D, Girardo S, Pagliara S, Ekpenyong A, Jacobi A, Wobus M, Töpfner N, Keyser UF, Mansfeld J, Fischer-Friedrich E, Guck J.

Nat Methods. 2015 Mar;12(3):199-202, 4 p following 202. doi: 10.1038/nmeth.3281. Epub 2015 Feb 2.

PMID:
25643151
18.

Phospholipase A(2)-catalyzed acylation of lysophospholipids analyzed by experimental design.

Lux G, Mansfeld J, Ulbrich-Hofmann R.

Enzyme Microb Technol. 2014 Oct;64-65:60-6. doi: 10.1016/j.enzmictec.2014.07.003. Epub 2014 Jul 22.

PMID:
25152418
19.

D-Glucosamine supplementation extends life span of nematodes and of ageing mice.

Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, Merry TL, Dubuis S, Laube B, Pfeiffer AF, Schulz TJ, Guthke R, Platzer M, Zamboni N, Zarse K, Ristow M.

Nat Commun. 2014 Apr 8;5:3563. doi: 10.1038/ncomms4563.

20.

Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.

Segref A, Kevei É, Pokrzywa W, Schmeisser K, Mansfeld J, Livnat-Levanon N, Ensenauer R, Glickman MH, Ristow M, Hoppe T.

Cell Metab. 2014 Apr 1;19(4):642-52. doi: 10.1016/j.cmet.2014.01.016.

21.

Probing selected structural regions in the secreted phospholipase A₂ from Arabidopsis thaliana for their impact on stability and activity.

Mansfeld J, Schöpfel M, Lorenz J, Trutschel T, Heilmann I, Brandt W, Ulbrich-Hofmann R.

Biochimie. 2014 Jun;101:60-6. doi: 10.1016/j.biochi.2013.12.015. Epub 2014 Jan 2.

PMID:
24389456
22.

High-density lipoprotein maintains skeletal muscle function by modulating cellular respiration in mice.

Lehti M, Donelan E, Abplanalp W, Al-Massadi O, Habegger KM, Weber J, Ress C, Mansfeld J, Somvanshi S, Trivedi C, Keuper M, Ograjsek T, Striese C, Cucuruz S, Pfluger PT, Krishna R, Gordon SM, Silva RA, Luquet S, Castel J, Martinez S, D'Alessio D, Davidson WS, Hofmann SM.

Circulation. 2013 Nov 26;128(22):2364-71. doi: 10.1161/CIRCULATIONAHA.113.001551. Epub 2013 Oct 29.

23.

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

Schmeisser K, Mansfeld J, Kuhlow D, Weimer S, Priebe S, Heiland I, Birringer M, Groth M, Segref A, Kanfi Y, Price NL, Schmeisser S, Schuster S, Pfeiffer AF, Guthke R, Platzer M, Hoppe T, Cohen HY, Zarse K, Sinclair DA, Ristow M.

Nat Chem Biol. 2013 Nov;9(11):693-700. doi: 10.1038/nchembio.1352. Epub 2013 Sep 29.

24.

Differences in the effect of phosphatidylinositol 4,5-bisphosphate on the hydrolytic and transphosphatidylation activities of membrane-bound phospholipase D from poppy seedlings.

Oblozinsky M, Bezakova L, Mansfeld J, Heilmann I, Ulbrich-Hofmann R.

Plant Physiol Biochem. 2013 Aug;69:39-42. doi: 10.1016/j.plaphy.2013.04.005. Epub 2013 Apr 25.

PMID:
23712013
25.

Role of adipose and hepatic atypical protein kinase C lambda (PKCλ) in the development of obesity and glucose intolerance.

Habegger KM, Matzke D, Ottaway N, Hembree J, Holland J, Raver C, Mansfeld J, Müller TD, Perez-Tilve D, Pfluger PT, Lee SJ, Diaz-Meco M, Moscat J, Leitges M, Tschöp MH, Hofmann SM.

Adipocyte. 2012 Oct 1;1(4):203-214.

26.

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

Mansfeld J, Collin P, Collins MO, Choudhary JS, Pines J.

Nat Cell Biol. 2011 Sep 18;13(10):1234-43. doi: 10.1038/ncb2347.

27.

Discrimination between the regioisomeric 1,2- and 1,3-diacylglycerophosphocholines by phospholipases.

Mansfeld J, Brandt W, Haftendorn R, Schöps R, Ulbrich-Hofmann R.

Chem Phys Lipids. 2011 Mar;164(3):196-204. doi: 10.1016/j.chemphyslip.2010.12.009. Epub 2010 Dec 30.

PMID:
21195068
28.

The transphosphatidylation potential of a membrane-bound phospholipase D from poppy seedlings.

Oblozinsky M, Bezakova L, Mansfeld J, Ulbrich-Hofmann R.

Phytochemistry. 2011 Feb;72(2-3):160-5. doi: 10.1016/j.phytochem.2010.11.020. Epub 2010 Dec 18.

PMID:
21168889
29.

Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane.

Mitchell JM, Mansfeld J, Capitanio J, Kutay U, Wozniak RW.

J Cell Biol. 2010 Nov 1;191(3):505-21. doi: 10.1083/jcb.201007098. Epub 2010 Oct 25.

30.

Disulfide bonds of phospholipase A2 from bee venom yield discrete contributions to its conformational stability.

Welker S, Markert Y, Köditz J, Mansfeld J, Ulbrich-Hofmann R.

Biochimie. 2011 Feb;93(2):195-201. doi: 10.1016/j.biochi.2010.09.012. Epub 2010 Sep 25.

PMID:
20884319
31.

Refolding of the non-specific neutral protease from Bacillus stearothermophilus proceeds via an autoproteolytically sensitive intermediate.

Dürrschmidt P, Mansfeld J, Ulbrich-Hofmann R.

Biophys Chem. 2010 Mar;147(1-2):66-73. doi: 10.1016/j.bpc.2010.01.001. Epub 2010 Jan 13.

PMID:
20096501
32.

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.

Garnett MJ, Mansfeld J, Godwin C, Matsusaka T, Wu J, Russell P, Pines J, Venkitaraman AR.

Nat Cell Biol. 2009 Nov;11(11):1363-9. doi: 10.1038/ncb1983. Epub 2009 Oct 11.

33.

Plant phospholipases A2: perspectives on biotechnological applications.

Mansfeld J.

Biotechnol Lett. 2009 Sep;31(9):1373-80. doi: 10.1007/s10529-009-0034-1. Epub 2009 May 29. Review.

PMID:
19479320
34.

Modulation of phospholipase D activity in vitro.

Mansfeld J, Ulbrich-Hofmann R.

Biochim Biophys Acta. 2009 Sep;1791(9):913-26. doi: 10.1016/j.bbalip.2009.03.003. Epub 2009 Mar 12. Review.

PMID:
19286472
35.

Secretory phospholipase A2-alpha from Arabidopsis thaliana: functional parameters and substrate preference.

Mansfeld J, Ulbrich-Hofmann R.

Chem Phys Lipids. 2007 Dec;150(2):156-66. Epub 2007 Jul 10.

PMID:
17692835
36.

Alpha-amylase from mung beans (Vigna radiata)--correlation of biochemical properties and tertiary structure by homology modelling.

Tripathi P, Lo Leggio L, Mansfeld J, Ulbrich-Hofmann R, Kayastha AM.

Phytochemistry. 2007 Jun;68(12):1623-31. Epub 2007 May 23.

PMID:
17524440
37.

The actin multigene family of Paramecium tetraurelia.

Sehring IM, Mansfeld J, Reiner C, Wagner E, Plattner H, Kissmehl R.

BMC Genomics. 2007 Mar 28;8:82.

38.

Production of synthetically created phospholipase A(2) variants with industrial impact.

Markert Y, Mansfeld J, Schierhorn A, Rücknagel KP, Ulbrich-Hofmann R.

Biotechnol Bioeng. 2007 Sep 1;98(1):48-59.

PMID:
17318911
39.

A broad spectrum of actin paralogs in Paramecium tetraurelia cells display differential localization and function.

Sehring IM, Reiner C, Mansfeld J, Plattner H, Kissmehl R.

J Cell Sci. 2007 Jan 1;120(Pt 1):177-90. Epub 2006 Dec 12.

40.
41.

Probing conserved amino acids in phospholipase D (Brassica oleracea var. capitata) for their importance in hydrolysis and transphosphatidylation activity.

Lerchner A, Mansfeld J, Kuppe K, Ulbrich-Hofmann R.

Protein Eng Des Sel. 2006 Oct;19(10):443-52. Epub 2006 Jul 14.

PMID:
16845127
42.

Secretory phospholipase A2 from Arabidopsis thaliana: insights into the three-dimensional structure and the amino acids involved in catalysis.

Mansfeld J, Gebauer S, Dathe K, Ulbrich-Hofmann R.

Biochemistry. 2006 May 9;45(18):5687-94.

PMID:
16669612
43.

The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells.

Mansfeld J, Güttinger S, Hawryluk-Gara LA, Panté N, Mall M, Galy V, Haselmann U, Mühlhäusser P, Wozniak RW, Mattaj IW, Kutay U, Antonin W.

Mol Cell. 2006 Apr 7;22(1):93-103.

44.

A multigene family encoding R-SNAREs in the ciliate Paramecium tetraurelia.

Schilde C, Wassmer T, Mansfeld J, Plattner H, Kissmehl R.

Traffic. 2006 Apr;7(4):440-55.

45.

Two highly homologous phospholipase D isoenzymes from Papaver somniferum L. with different transphosphatidylation potential.

Lerchner A, Mansfeld J, Schäffner I, Schöps R, Beer HK, Ulbrich-Hofmann R.

Biochim Biophys Acta. 2005 Dec 15;1737(2-3):94-101. Epub 2005 Oct 7.

PMID:
16257263
46.

An engineered disulfide bridge mimics the effect of calcium to protect neutral protease against local unfolding.

Dürrschmidt P, Mansfeld J, Ulbrich-Hofmann R.

FEBS J. 2005 Mar;272(6):1523-34.

47.

The propeptide is not required to produce catalytically active neutral protease from Bacillus stearothermophilus.

Mansfeld J, Petermann E, Dürrschmidt P, Ulbrich-Hofmann R.

Protein Expr Purif. 2005 Feb;39(2):219-28.

PMID:
15642473
48.

Identification of phospholipase D from cabbage as N-terminally acetylated PLD2.

Schöps R, Schierhorn A, Schäffner I, Mansfeld J, Ulbrich-Hofmann R.

J Protein Chem. 2002 Aug;21(6):407-11.

PMID:
12492151
49.

Boilysin and thermolysin in dipeptide synthesis: a comparative study.

Kühn D, Dürrschmidt P, Mansfeld J, Ulbrich-Hofmann R.

Biotechnol Appl Biochem. 2002 Aug;36(Pt 1):71-6.

PMID:
12149125
50.

Increased proteolytic resistance of ribonuclease A by protein engineering.

Markert Y, Köditz J, Mansfeld J, Arnold U, Ulbrich-Hofmann R.

Protein Eng. 2001 Oct;14(10):791-6.

PMID:
11739898

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