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Items: 19


Daratumumab in Sensitized Kidney Transplantation: Potentials and Limitations of Experimental and Clinical Use.

Kwun J, Matignon M, Manook M, Guendouz S, Audard V, Kheav D, Poullot E, Gautreau C, Ezekian B, Bodez D, Damy T, Faivre L, Menouch D, Yoon J, Park J, Belhadj K, Chen D, Bilewski AM, Yi JS, Collins B, Stegall M, Farris AB, Knechtle S, Grimbert P.

J Am Soc Nephrol. 2019 Jul;30(7):1206-1219. doi: 10.1681/ASN.2018121254. Epub 2019 Jun 21.


For the many: permitting deceased donor kidney transplantation across low-titre blood group antibodies can reduce wait times for blood group B recipients, and improve the overall number of 000MM transplants - a multicentre observational cohort study.

Manook M, Mumford L, Barnett ANR, Osei-Bordom D, Sandhu B, Veniard D, Maggs T, Shaw O, Kessaris N, Dorling A, Shah S, Mamode N.

Transpl Int. 2019 Apr;32(4):431-442. doi: 10.1111/tri.13389. Epub 2019 Jan 21.


Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients.

Burghuber CK, Manook M, Ezekian B, Gibby AC, Leopardi FV, Song M, Jenks J, Saccoccio F, Permar S, Farris AB, Iwakoshi NN, Kwun J, Knechtle SJ.

Am J Transplant. 2019 Mar;19(3):724-736. doi: 10.1111/ajt.15067. Epub 2018 Sep 17.


'Hepworth hitch': parastomal hernia prevention by simple modifications of operative techniques.

Manook M, Almoudaris AM, Zosimas D, Hayles K, Hepworth C.

Tech Coloproctol. 2018 Jun;22(6):461-463. doi: 10.1007/s10151-018-1808-z. Epub 2018 Jul 3. No abstract available.


Innate networking: Thrombotic microangiopathy, the activation of coagulation and complement in the sensitized kidney transplant recipient.

Manook M, Kwun J, Sacks S, Dorling A, Mamode N, Knechtle S.

Transplant Rev (Orlando). 2018 Jul;32(3):119-126. doi: 10.1016/j.trre.2018.01.001. Epub 2018 Feb 10. Review.


Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates.

Kwun J, Burghuber C, Manook M, Ezekian B, Park J, Yoon J, Yi JS, Iwakoshi N, Gibby A, Hong JJ, Farris AB, Kirk AD, Knechtle SJ.

Blood Adv. 2017 Oct 26;1(24):2115-2119. doi: 10.1182/bloodadvances.2017010991. eCollection 2017 Nov 14. Erratum in: Blood Adv. 2018 Jan 23;2(2):89.


Humoral Compensation after Bortezomib Treatment of Allosensitized Recipients.

Kwun J, Burghuber C, Manook M, Iwakoshi N, Gibby A, Hong JJ, Knechtle S.

J Am Soc Nephrol. 2017 Jul;28(7):1991-1996. doi: 10.1681/ASN.2016070727. Epub 2017 Feb 23.


Thrombalexin: Use of a Cytotopic Anticoagulant to Reduce Thrombotic Microangiopathy in a Highly Sensitized Model of Kidney Transplantation.

Manook M, Kwun J, Burghuber C, Samy K, Mulvihill M, Yoon J, Xu H, MacDonald AL, Freischlag K, Curfman V, Branum E, Howell D, Farris AB, Smith RA, Sacks S, Dorling A, Mamode N, Knechtle SJ.

Am J Transplant. 2017 Aug;17(8):2055-2064. doi: 10.1111/ajt.14234. Epub 2017 Mar 23. Erratum in: Am J Transplant. 2017 Nov;17 (11):2993.


Post-listing survival for highly sensitised patients on the UK kidney transplant waiting list: a matched cohort analysis.

Manook M, Koeser L, Ahmed Z, Robb M, Johnson R, Shaw O, Kessaris N, Dorling A, Mamode N.

Lancet. 2017 Feb 18;389(10070):727-734. doi: 10.1016/S0140-6736(16)31595-1. Epub 2017 Jan 6. Erratum in: Lancet. 2017 Feb 18;389(10070):700.


Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis.

Lee J, Jackman JG, Kwun J, Manook M, Moreno A, Elster EA, Kirk AD, Leong KW, Sullenger BA.

Biomaterials. 2017 Mar;120:94-102. doi: 10.1016/j.biomaterials.2016.12.024. Epub 2016 Dec 23.


Crosstalk Between T and B Cells in the Germinal Center After Transplantation.

Kwun J, Manook M, Page E, Burghuber C, Hong J, Knechtle SJ.

Transplantation. 2017 Apr;101(4):704-712. doi: 10.1097/TP.0000000000001588. Review.


Antibody-Mediated Rejection in Sensitized Nonhuman Primates: Modeling Human Biology.

Burghuber CK, Kwun J, Page EJ, Manook M, Gibby AC, Leopardi FV, Song M, Farris AB 3rd, Hong JJ, Villinger F, Adams AB, Iwakoshi NN, Knechtle SJ.

Am J Transplant. 2016 Jun;16(6):1726-38. doi: 10.1111/ajt.13688. Epub 2016 Mar 25.


Incidence and Outcome of C4d Staining With Tubulointerstitial Inflammation in Blood Group-incompatible Kidney Transplantation.

Couzi L, Perera R, Manook M, Barnett AN, Shaw O, Kessaris N, Marks SD, Dorling A, Mamode N.

Transplantation. 2015 Jul;99(7):1487-94. doi: 10.1097/TP.0000000000000556.


Difference in outcomes after antibody-mediated rejection between abo-incompatible and positive cross-match transplantations.

Couzi L, Manook M, Perera R, Shaw O, Ahmed Z, Kessaris N, Dorling A, Mamode N.

Transpl Int. 2015 Oct;28(10):1205-15. doi: 10.1111/tri.12621. Epub 2015 Jul 6.


Tailored desensitization strategies in ABO blood group antibody incompatible renal transplantation.

Barnett AN, Manook M, Nagendran M, Kenchayikoppad S, Vaughan R, Dorling A, Hadjianastassiou VG, Mamode N.

Transpl Int. 2014 Feb;27(2):187-96. doi: 10.1111/tri.12234. Epub 2013 Dec 28.


Early changes in scores of chronic damage on transplant kidney protocol biopsies reflect donor characteristics, but not future graft function.

Caplin B, Veighey K, Mahenderan A, Manook M, Henry J, Nitsch D, Harber M, Dupont P, Wheeler DC, Jones G, Fernando B, Howie AJ, Veitch P.

Clin Transplant. 2013 Nov-Dec;27(6):E669-78. doi: 10.1111/ctr.12251. Epub 2013 Oct 9.


A new reconstructive technique for posterior vaginal wall defects, a case report.

Zetlitz E, Manook M, MacLeod A, Hamilton S.

J Sex Med. 2013 Oct;10(10):2579-81. doi: 10.1111/jsm.12056. Epub 2013 Jan 24.


Practical aspects of arteriovenous fistula formation in the pediatric population.

Manook M, Calder F.

Pediatr Nephrol. 2013 Jun;28(6):885-93. doi: 10.1007/s00467-012-2328-0. Epub 2012 Oct 27. Review.


Spontaneous brainstem hematoma with hydrocephalus.

Balasubramanian C, Manook M, Russell T.

Neurosurg Rev. 2008 Jul;31(3):355-6; author reply 356. doi: 10.1007/s10143-008-0139-3. Epub 2008 Apr 29. No abstract available.


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