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Items: 15


Control of Plasma Membrane Permeability by ABC Transporters.

Khakhina S, Johnson SS, Manoharlal R, Russo SB, Blugeon C, Lemoine S, Sunshine AB, Dunham MJ, Cowart LA, Devaux F, Moye-Rowley WS.

Eukaryot Cell. 2015 May;14(5):442-53. doi: 10.1128/EC.00021-15. Epub 2015 Feb 27.


In vitro effect of malachite green on Candida albicans involves multiple pathways and transcriptional regulators UPC2 and STP2.

Dhamgaye S, Devaux F, Manoharlal R, Vandeputte P, Shah AH, Singh A, Blugeon C, Sanglard D, Prasad R.

Antimicrob Agents Chemother. 2012 Jan;56(1):495-506. doi: 10.1128/AAC.00574-11. Epub 2011 Oct 17.


Overcoming the heterologous bias: an in vivo functional analysis of multidrug efflux transporter, CgCdr1p in matched pair clinical isolates of Candida glabrata.

Puri N, Manoharlal R, Sharma M, Sanglard D, Prasad R.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):357-63. doi: 10.1016/j.bbrc.2010.11.123. Epub 2010 Dec 4.


Regulation of yeast nutrient permease endocytosis by ATP-binding cassette transporters and a seven-transmembrane protein, RSB1.

Johnson SS, Hanson PK, Manoharlal R, Brice SE, Cowart LA, Moye-Rowley WS.

J Biol Chem. 2010 Nov 12;285(46):35792-802. doi: 10.1074/jbc.M110.162883. Epub 2010 Sep 8.


Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.

Puri N, Prakash O, Manoharlal R, Sharma M, Ghosh I, Prasad R.

Eur J Med Chem. 2010 Nov;45(11):4813-26. doi: 10.1016/j.ejmech.2010.07.050. Epub 2010 Aug 10.


Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis.

Sharma M, Manoharlal R, Negi AS, Prasad R.

FEMS Yeast Res. 2010 Aug 1;10(5):570-8. doi: 10.1111/j.1567-1364.2010.00637.x. Epub 2010 Apr 23.


Morphogenic regulator EFG1 affects the drug susceptibilities of pathogenic Candida albicans.

Prasad T, Hameed S, Manoharlal R, Biswas S, Mukhopadhyay CK, Goswami SK, Prasad R.

FEMS Yeast Res. 2010 Aug 1;10(5):587-96. doi: 10.1111/j.1567-1364.2010.00639.x. Epub 2010 May 29.


Molecular determinants of transient and reversible induced up-regulation of CaCDR1 in azole susceptible clinical isolates of Candida albicans.

Manoharlal R, Sharma M, Prasad R.

Biosci Rep. 2011 Feb;31(1):31-43. doi: 10.1042/BSR20100015.


PAP1 [poly(A) polymerase 1] homozygosity and hyperadenylation are major determinants of increased mRNA stability of CDR1 in azole-resistant clinical isolates of Candida albicans.

Manoharlal R, Gorantala J, Sharma M, Sanglard D, Prasad R.

Microbiology. 2010 Feb;156(Pt 2):313-26. doi: 10.1099/mic.0.035154-0. Epub 2009 Nov 12.


Differential dynamics of membrane proteins in yeast.

Ganguly S, Singh P, Manoharlal R, Prasad R, Chattopadhyay A.

Biochem Biophys Res Commun. 2009 Oct 2;387(4):661-5. doi: 10.1016/j.bbrc.2009.07.054. Epub 2009 Jul 16.


Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals.

Sharma M, Manoharlal R, Shukla S, Puri N, Prasad T, Ambudkar SV, Prasad R.

Antimicrob Agents Chemother. 2009 Aug;53(8):3256-65. doi: 10.1128/AAC.01497-08. Epub 2009 May 26.


MFS transportome of the human pathogenic yeast Candida albicans.

Gaur M, Puri N, Manoharlal R, Rai V, Mukhopadhayay G, Choudhury D, Prasad R.

BMC Genomics. 2008 Dec 3;9:579. doi: 10.1186/1471-2164-9-579.


Transcriptional activation and increased mRNA stability contribute to overexpression of CDR1 in azole-resistant Candida albicans.

Manoharlal R, Gaur NA, Panwar SL, Morschhäuser J, Prasad R.

Antimicrob Agents Chemother. 2008 Apr;52(4):1481-92. doi: 10.1128/AAC.01106-07. Epub 2008 Feb 11.


Expression of the CDR1 efflux pump in clinical Candida albicans isolates is controlled by a negative regulatory element.

Gaur NA, Manoharlal R, Saini P, Prasad T, Mukhopadhyay G, Hoefer M, Morschhäuser J, Prasad R.

Biochem Biophys Res Commun. 2005 Jun 24;332(1):206-14.


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