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Does neck pain as chief complaint influence the outcome of cervical total disc replacement?

Finkenstaedt S, Mannion AF, Fekete TF, Haschtmann D, Kleinstueck FS, Mutter U, Becker HJ, Bellut D, Porchet F.

Eur Spine J. 2019 Jul 8. doi: 10.1007/s00586-019-06052-8. [Epub ahead of print]


Genotoxic Escherichia coli Strains Encoding Colibactin, Cytolethal Distending Toxin, and Cytotoxic Necrotizing Factor in Laboratory Rats.

Kurnick SA, Mannion AJ, Feng Y, Madden CM, Chamberlain P, Fox JG.

Comp Med. 2019 Apr 1;69(2):103-113. doi: 10.30802/AALAS-CM-18-000099. Epub 2019 Mar 22.


Surgical training in spine surgery: safety and patient-rated outcome.

Waisbrod G, Mannion AF, Fekete TF, Kleinstueck F, Jeszenszky D, Haschtmann D.

Eur Spine J. 2019 Apr;28(4):807-816. doi: 10.1007/s00586-019-05883-9. Epub 2019 Jan 29.


Characterization of Campylobacter jejuni, Campylobacter upsaliensis, and a novel Campylobacter sp. in a captive non-human primate zoological collection.

Clayton JB, Danzeisen JL, Johnson TJ, Trent AM, Hayer SS, Murphy T, Wuenschmann A, Elder M, Shen Z, Mannion A, Bryant E, Knights D, Fox JG.

J Med Primatol. 2019 Apr;48(2):114-122. doi: 10.1111/jmp.12393. Epub 2018 Dec 9.


Gamma-glutamyltranspeptidase expression by Helicobacter saguini, an enterohepatic Helicobacter species isolated from cotton top tamarins with chronic colitis.

Mannion A, Shen Z, Feng Y, Artim SC, Ravindra K, Ge Z, Fox JG.

Cell Microbiol. 2019 Mar;21(3):e12968. doi: 10.1111/cmi.12968. Epub 2018 Nov 14.


Validation and cross-cultural adaptation of the Korean version of the Core Outcome Measures Index in patients with degenerative lumbar disease.

Kim HJ, Yeom JS, Nam Y, Lee NK, Heo YW, Lee SY, Park J, Chang BS, Lee CK, Chun HJ, Mannion AF.

Eur Spine J. 2018 Nov;27(11):2804-2813. doi: 10.1007/s00586-018-5759-x. Epub 2018 Sep 17.


Factors associated with having an indication for surgery in adult spinal deformity: an international european multicentre study.

Richner-Wunderlin S, Mannion AF, Vila-Casademunt A, Pellise F, Serra-Burriel M, Seifert B, Aghayev E, Acaroglu E, Alanay A, Pérez-Grueso FJS, Obeid I, Kleinstück F; European Spine Study Group (ESSG).

Eur Spine J. 2019 Jan;28(1):127-137. doi: 10.1007/s00586-018-5754-2. Epub 2018 Sep 14.


An Investigation of Gelotophobia in Individuals with a Diagnosis of High-Functioning Autism Spectrum Disorder.

Leader G, Grennan S, Chen JL, Mannion A.

J Autism Dev Disord. 2018 Dec;48(12):4155-4166. doi: 10.1007/s10803-018-3661-3.


Impaired sleep predicts onset of low back pain and burnout symptoms: evidence from a three-wave study.

Elfering A, Kottwitz MU, Tamcan Ö, Müller U, Mannion AF.

Psychol Health Med. 2018 Dec;23(10):1196-1210. doi: 10.1080/13548506.2018.1479038. Epub 2018 May 24.


Helicobacter pylori-infected C57BL/6 mice with different gastrointestinal microbiota have contrasting gastric pathology, microbial and host immune responses.

Ge Z, Sheh A, Feng Y, Muthupalani S, Ge L, Wang C, Kurnick S, Mannion A, Whary MT, Fox JG.

Sci Rep. 2018 May 22;8(1):8014. doi: 10.1038/s41598-018-25927-2.


Plasmid-Mediated Quinolone Resistance in Shigella flexneri Isolated From Macaques.

Mannion AJ, Martin HR, Shen Z, Buckley EM, Dzink-Fox JL, Garcia A, Marini RP, Patterson MM, Fox JG.

Front Microbiol. 2018 Mar 5;9:311. doi: 10.3389/fmicb.2018.00311. eCollection 2018.


Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis.

Bakthavatchalu V, Wert KJ, Feng Y, Mannion A, Ge Z, Garcia A, Scott KE, Caron TJ, Madden CM, Jacobsen JT, Victora G, Jaenisch R, Fox JG.

PLoS One. 2018 Mar 19;13(3):e0194443. doi: 10.1371/journal.pone.0194443. eCollection 2018.


WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer.

Poujade FA, Mannion A, Brittain N, Theodosi A, Beeby E, Leszczynska KB, Hammond EM, Greenman J, Cawthorne C, Pires IM.

Br J Cancer. 2018 May;118(9):1229-1237. doi: 10.1038/s41416-018-0056-3. Epub 2018 Mar 15.


Relative pelvic version: an individualized pelvic incidence-based proportional parameter that quantifies pelvic version more precisely than pelvic tilt.

Yilgor C, Yavuz Y, Sogunmez N, Haddad S, Mannion AF, Abul K, Boissiere L, Obeid I, Kleinstück F, Pérez-Grueso FJS, Acaroglu E, Pellise F, Alanay A; European Spine Study Group (ESSG).

Spine J. 2018 Oct;18(10):1787-1797. doi: 10.1016/j.spinee.2018.03.001. Epub 2018 Mar 8.


Development of the Japanese Core Outcome Measures Index (COMI): cross-cultural adaptation and psychometric validation.

Matsudaira K, Oka H, Oshima Y, Chikuda H, Taniguchi Y, Matsubayashi Y, Kawaguchi M, Sato E, Murano H, Laurent T, Tanaka S, Mannion AF.

BMC Musculoskelet Disord. 2018 Mar 2;19(1):71. doi: 10.1186/s12891-018-1986-x.


EUROSPINE 2017 FULL PAPER AWARD: Time to remove our rose-tinted spectacles: a candid appraisal of the relative success of surgery in over 4500 patients with degenerative disorders of the lumbar spine, hip or knee.

Mannion AF, Impellizzeri FM, Leunig M, Jeszenszy D, Becker HJ, Haschtmann D, Preiss S, Fekete TF.

Eur Spine J. 2018 Apr;27(4):778-788. doi: 10.1007/s00586-018-5469-4. Epub 2018 Feb 19.


Cytotoxic Escherichia coli strains encoding colibactin and cytotoxic necrotizing factor (CNF) colonize laboratory macaques.

Feng Y, Mannion A, Madden CM, Swennes AG, Townes C, Byrd C, Marini RP, Fox JG.

Gut Pathog. 2017 Dec 6;9:71. doi: 10.1186/s13099-017-0220-y. eCollection 2017.


Relative lumbar lordosis and lordosis distribution index: individualized pelvic incidence-based proportional parameters that quantify lumbar lordosis more precisely than the concept of pelvic incidence minus lumbar lordosis.

Yilgor C, Sogunmez N, Yavuz Y, Abul K, Boissiére L, Haddad S, Obeid I, Kleinstück F, Sánchez Pérez-Grueso FJ, Acaroğlu E, Mannion AF, Pellise F, Alanay A; European Spine Study Group.

Neurosurg Focus. 2017 Dec;43(6):E5. doi: 10.3171/2017.8.FOCUS17498.


How does patient-rated outcome change over time following the surgical treatment of degenerative disorders of the thoracolumbar spine?

Fekete TF, Loibl M, Jeszenszky D, Haschtmann D, Banczerowski P, Kleinstück FS, Becker HJ, Porchet F, Mannion AF.

Eur Spine J. 2018 Mar;27(3):700-708. doi: 10.1007/s00586-017-5358-2. Epub 2017 Oct 27.


Global Alignment and Proportion (GAP) Score: Development and Validation of a New Method of Analyzing Spinopelvic Alignment to Predict Mechanical Complications After Adult Spinal Deformity Surgery.

Yilgor C, Sogunmez N, Boissiere L, Yavuz Y, Obeid I, Kleinstück F, Pérez-Grueso FJS, Acaroglu E, Haddad S, Mannion AF, Pellise F, Alanay A; European Spine Study Group (ESSG).

J Bone Joint Surg Am. 2017 Oct 4;99(19):1661-1672. doi: 10.2106/JBJS.16.01594.


Interacting with Dementia: The MARIO Approach.

Kouroupetroglou C, Casey D, Raciti M, Barrett E, D'Onofrio G, Ricciardi F, Giuliani F, Greco A, Sancarlo D, Mannion A, Whelan S, Pegman G, Koumpis A, Reforgiato Recupero D, Kouroupetroglou A, Santorelli A.

Stud Health Technol Inform. 2017;242:38-47.


Factor analysis of the SRS-22 outcome assessment instrument in patients with adult spinal deformity.

Mannion AF, Elfering A, Bago J, Pellise F, Vila-Casademunt A, Richner-Wunderlin S, Domingo-Sàbat M, Obeid I, Acaroglu E, Alanay A, Pérez-Grueso FS, Baldus CR, Carreon LY, Bridwell KH, Glassman SD, Kleinstück F; European Spine Study Group (ESSG).

Eur Spine J. 2018 Mar;27(3):685-699. doi: 10.1007/s00586-017-5279-0. Epub 2017 Sep 2.


Dural sac cross-sectional area and morphological grade show significant associations with patient-rated outcome of surgery for lumbar central spinal stenosis.

Mannion AF, Fekete TF, Pacifico D, O'Riordan D, Nauer S, von Büren M, Schizas C.

Eur Spine J. 2017 Oct;26(10):2552-2564. doi: 10.1007/s00586-017-5280-7. Epub 2017 Aug 30.


The Adult Deformity Surgery Complexity Index (ADSCI): a valid tool to quantify the complexity of posterior adult spinal deformity surgery and predict postoperative complications.

Pellisé F, Vila-Casademunt A, Núñez-Pereira S, Domingo-Sàbat M, Bagó J, Vidal X, Alanay A, Acaroglu E, Kleinstück F, Obeid I, Pérez-Grueso FJS, Lafage V, Bess S, Ames C, Mannion AF; European Spine Study Group.

Spine J. 2018 Feb;18(2):216-225. doi: 10.1016/j.spinee.2017.06.042. Epub 2017 Jul 4.


Incidental durotomy in decompression for lumbar spinal stenosis: incidence, risk factors and effect on outcomes in the Spine Tango registry.

Herren C, Sobottke R, Mannion AF, Zweig T, Munting E, Otten P, Pigott T, Siewe J, Aghayev E; Spine Tango Contributors.

Eur Spine J. 2017 Oct;26(10):2483-2495. doi: 10.1007/s00586-017-5197-1. Epub 2017 Jun 20.


Novel urease-negative Helicobacter sp. 'H. enhydrae sp. nov.' isolated from inflamed gastric tissue of southern sea otters.

Shen Z, Batac F, Mannion A, Miller MA, Bakthavatchalu V, Ho C, Manning S, Paster BJ, Fox JG.

Dis Aquat Organ. 2017 Feb 8;123(1):1-11. doi: 10.3354/dao03082.


Outcome of L5 radiculopathy after reduction and instrumented transforaminal lumbar interbody fusion of high-grade L5-S1 isthmic spondylolisthesis and the role of intraoperative neurophysiological monitoring.

Schär RT, Sutter M, Mannion AF, Eggspühler A, Jeszenszky D, Fekete TF, Kleinstück F, Haschtmann D.

Eur Spine J. 2017 Mar;26(3):679-690. doi: 10.1007/s00586-017-4964-3. Epub 2017 Jan 31.


Is the duration of pre-operative conservative treatment associated with the clinical outcome following surgical decompression for lumbar spinal stenosis? A study based on the Spine Tango Registry.

Zweig T, Enke J, Mannion AF, Sobottke R, Melloh M, Freeman BJ, Aghayev E; Spine Tango Contributors.

Eur Spine J. 2017 Feb;26(2):488-500. doi: 10.1007/s00586-016-4882-9. Epub 2016 Dec 15.


The use of the Core Outcome Measures Index (COMI) in patients undergoing total knee replacement.

Impellizzeri FM, Leunig M, Preiss S, Guggi T, Mannion AF.

Knee. 2017 Mar;24(2):372-379. doi: 10.1016/j.knee.2016.11.016. Epub 2016 Dec 13.


A novel use of the Spine Tango registry to evaluate selection bias in patient recruitment into clinical studies: an analysis of patients participating in the Lumbar Spinal Stenosis Outcome Study (LSOS).

Becker HJ, Nauer S, Porchet F, Kleinstück FS, Haschtmann D, Fekete TF, Steurer J, Mannion AF.

Eur Spine J. 2017 Feb;26(2):441-449. doi: 10.1007/s00586-016-4850-4. Epub 2016 Nov 14.


Draft Genome Sequences of Five Novel Polyketide Synthetase-Containing Mouse Escherichia coli Strains.

Mannion A, Shen Z, Feng Y, Garcia A, Fox JG.

Genome Announc. 2016 Oct 6;4(5). pii: e01082-16. doi: 10.1128/genomeA.01082-16.


Cytotoxic Escherichia coli strains encoding colibactin colonize laboratory mice.

García A, Mannion A, Feng Y, Madden CM, Bakthavatchalu V, Shen Z, Ge Z, Fox JG.

Microbes Infect. 2016 Dec;18(12):777-786. doi: 10.1016/j.micinf.2016.07.005. Epub 2016 Jul 30.


Patient-reported outcome of surgical treatment for lumbar spinal epidural lipomatosis.

Ferlic PW, Mannion AF, Jeszenszky D, Porchet F, Fekete TF, Kleinstück F, Haschtmann D.

Spine J. 2016 Nov;16(11):1333-1341. doi: 10.1016/j.spinee.2016.06.022. Epub 2016 Jun 27.


Determination of the Oswestry Disability Index score equivalent to a "satisfactory symptom state" in patients undergoing surgery for degenerative disorders of the lumbar spine-a Spine Tango registry-based study.

van Hooff ML, Mannion AF, Staub LP, Ostelo RW, Fairbank JC.

Spine J. 2016 Oct;16(10):1221-1230. doi: 10.1016/j.spinee.2016.06.010. Epub 2016 Jun 22.


Helicobacter saguini, a Novel Helicobacter Isolated from Cotton-Top Tamarins with Ulcerative Colitis, Has Proinflammatory Properties and Induces Typhlocolitis and Dysplasia in Gnotobiotic IL-10-/- Mice.

Shen Z, Mannion A, Whary MT, Muthupalani S, Sheh A, Feng Y, Gong G, Vandamme P, Holcombe HR, Paster BJ, Fox JG.

Infect Immun. 2016 Jul 21;84(8):2307-2316. doi: 10.1128/IAI.00235-16. Print 2016 Aug.


Preferred patient-rated outcome measure in patients with femoroacetabular impingement: a comparison between selected instruments.

Impellizzeri FM, Naal FD, Mannion AF, Leunig M.

J Hip Preserv Surg. 2015 Aug 12;2(4):364-8. doi: 10.1093/jhps/hnv057. eCollection 2015 Dec.


What level of pain are patients happy to live with after surgery for lumbar degenerative disorders?

Fekete TF, Haschtmann D, Kleinstück FS, Porchet F, Jeszenszky D, Mannion AF.

Spine J. 2016 Apr;16(4 Suppl):S12-8. doi: 10.1016/j.spinee.2016.01.180. Epub 2016 Feb 2.


ISSLS Prize Winner: Consensus on the Clinical Diagnosis of Lumbar Spinal Stenosis: Results of an International Delphi Study.

Tomkins-Lane C, Melloh M, Lurie J, Smuck M, Battié MC, Freeman B, Samartzis D, Hu R, Barz T, Stuber K, Schneider M, Haig A, Schizas C, Cheung JP, Mannion AF, Staub L, Comer C, Macedo L, Ahn SH, Takahashi K, Sandella D.

Spine (Phila Pa 1976). 2016 Aug 1;41(15):1239-46. doi: 10.1097/BRS.0000000000001476.


Influence of previous surgery on patient-rated outcome after surgery for degenerative disorders of the lumbar spine.

Zehnder P, Aghayev E, Fekete TF, Haschtmann D, Pigott T, Mannion AF.

Eur Spine J. 2016 Aug;25(8):2553-62. doi: 10.1007/s00586-016-4383-x. Epub 2016 Jan 22.


Total disc arthroplasty versus anterior cervical interbody fusion: use of the Spine Tango registry to supplement the evidence from randomized control trials.

Staub LP, Ryser C, Röder C, Mannion AF, Jarvik JG, Aebi M, Aghayev E.

Spine J. 2016 Feb;16(2):136-45. doi: 10.1016/j.spinee.2015.11.056. Epub 2015 Dec 7.


Patient-Rated Outcomes of Lumbar Fusion in Patients With Degenerative Disease of the Lumbar Spine: Does Age Matter?

Marbacher S, Mannion AF, Burkhardt JK, Schär RT, Porchet F, Kleinstück F, Jeszenszky D, Fekete TF, Haschtmann D.

Spine (Phila Pa 1976). 2016 May;41(10):893-900. doi: 10.1097/BRS.0000000000001364.


The Core Outcome Measures Index (COMI) is a responsive instrument for assessing the outcome of treatment for adult spinal deformity.

Mannion AF, Vila-Casademunt A, Domingo-Sàbat M, Wunderlin S, Pellisé F, Bago J, Acaroglu E, Alanay A, Pérez-Grueso FS, Obeid I, Kleinstück FS; European Spine Study Group (ESSG).

Eur Spine J. 2016 Aug;25(8):2638-48. doi: 10.1007/s00586-015-4292-4. Epub 2015 Oct 30.


Age and pro-inflammatory gene polymorphisms influence adjacent segment disc degeneration more than fusion does in patients treated for chronic low back pain.

Omair A, Mannion AF, Holden M, Leivseth G, Fairbank J, Hägg O, Fritzell P, Brox JI.

Eur Spine J. 2016 Jan;25(1):2-13. doi: 10.1007/s00586-015-4181-x. Epub 2015 Aug 18.


Women demonstrate more pain and worse function before THA but comparable results 12 months after surgery.

Mannion AF, Impellizzeri FM, Naal FD, Leunig M.

Clin Orthop Relat Res. 2015 Dec;473(12):3849-57. doi: 10.1007/s11999-015-4479-3.


Influence of gender on patient-oriented outcomes in spine surgery.

Pochon L, Kleinstück FS, Porchet F, Mannion AF.

Eur Spine J. 2016 Jan;25(1):235-46. doi: 10.1007/s00586-015-4062-3. Epub 2015 Jul 5.


Predictors of improvement in quality of life and pain relief in lumbar spinal stenosis relative to patient age: a study based on the Spine Tango registry.

Sobottke R, Herren C, Siewe J, Mannion AF, Röder C, Aghayev E.

Eur Spine J. 2017 Feb;26(2):462-472. doi: 10.1007/s00586-015-4078-8. Epub 2015 Jul 3.


Could less be more when assessing patient-rated outcome in spinal stenosis?

Mannion AF, Fekete TF, Wertli MM, Mattle M, Nauer S, Kleinstück FS, Jeszenszky D, Haschtmann D, Becker HJ, Porchet F; Lumbar Spinal Stenosis Outcome Study (LSOS) Group.

Spine (Phila Pa 1976). 2015 May 15;40(10):710-8. doi: 10.1097/BRS.0000000000000751.

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