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Items: 10

1.

Pharmacokinetics of intra-articular vitamin D analogue calcipotriol in sheep and metabolism in human synovial and mesenchymal stromal cells.

Huovinen J, Haj Hussain M, Niemelä M, Laaksonen S, Voipio HM, Jyrkäs J, Mannila J, Lassila T, Tolonen A, Turunen S, Bergmann U, Lehenkari P, Huhtakangas JA.

J Steroid Biochem Mol Biol. 2019 Apr;188:172-184. doi: 10.1016/j.jsbmb.2018.12.006. Epub 2018 Dec 15.

PMID:
30562554
2.

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

Paquet T, Le Manach C, Cabrera DG, Younis Y, Henrich PP, Abraham TS, Lee MCS, Basak R, Ghidelli-Disse S, Lafuente-Monasterio MJ, Bantscheff M, Ruecker A, Blagborough AM, Zakutansky SE, Zeeman AM, White KL, Shackleford DM, Mannila J, Morizzi J, Scheurer C, Angulo-Barturen I, Martínez MS, Ferrer S, Sanz LM, Gamo FJ, Reader J, Botha M, Dechering KJ, Sauerwein RW, Tungtaeng A, Vanachayangkul P, Lim CS, Burrows J, Witty MJ, Marsh KC, Bodenreider C, Rochford R, Solapure SM, Jiménez-Díaz MB, Wittlin S, Charman SA, Donini C, Campo B, Birkholtz LM, Hanson KK, Drewes G, Kocken CHM, Delves MJ, Leroy D, Fidock DA, Waterson D, Street LJ, Chibale K.

Sci Transl Med. 2017 Apr 26;9(387). pii: eaad9735. doi: 10.1126/scitranslmed.aad9735.

3.

Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres.

Wang X, Dong Y, Wittlin S, Charman SA, Chiu FC, Chollet J, Katneni K, Mannila J, Morizzi J, Ryan E, Scheurer C, Steuten J, Santo Tomas J, Snyder C, Vennerstrom JL.

J Med Chem. 2013 Mar 28;56(6):2547-55. doi: 10.1021/jm400004u. Epub 2013 Mar 15.

PMID:
23489135
4.

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential.

Younis Y, Douelle F, Feng TS, González Cabrera D, Le Manach C, Nchinda AT, Duffy S, White KL, Shackleford DM, Morizzi J, Mannila J, Katneni K, Bhamidipati R, Zabiulla KM, Joseph JT, Bashyam S, Waterson D, Witty MJ, Hardick D, Wittlin S, Avery V, Charman SA, Chibale K.

J Med Chem. 2012 Apr 12;55(7):3479-87. doi: 10.1021/jm3001373. Epub 2012 Mar 21.

PMID:
22390538
5.

Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits.

Turunen E, Mannila J, Laitinen R, Riikonen J, Lehto VP, Järvinen T, Ketolainen J, Järvinen K, Jarho P.

J Pharm Pharmacol. 2011 Jan;63(1):19-25. doi: 10.1111/j.2042-7158.2010.01173.x. Epub 2010 Nov 16.

PMID:
21155811
6.

Cyclodextrins and chitosan derivatives in sublingual delivery of low solubility peptides: A study using cyclosporin A, alpha-cyclodextrin and quaternary chitosan N-betainate.

Mannila J, Järvinen K, Holappa J, Matilainen L, Auriola S, Jarho P.

Int J Pharm. 2009 Oct 20;381(1):19-24. doi: 10.1016/j.ijpharm.2009.07.012. Epub 2009 Jul 24.

PMID:
19632311
7.
8.

Sublingual administration of Delta9-tetrahydrocannabinol/beta-cyclodextrin complex increases the bioavailability of Delta9-tetrahydrocannabinol in rabbits.

Mannila J, Järvinen T, Järvinen K, Tervonen J, Jarho P.

Life Sci. 2006 Mar 20;78(17):1911-4. Epub 2005 Nov 2.

PMID:
16266727
9.

Effects of RM-beta-CD on sublingual bioavailability of Delta9-tetrahydrocannabinol in rabbits.

Mannila J, Järvinen T, Järvinen K, Tarvainen M, Jarho P.

Eur J Pharm Sci. 2005 Sep;26(1):71-7.

PMID:
15955678
10.

Determination of Delta9-tetrahydrocannabinol from rabbit plasma by gas chromatography-mass spectrometry using two ionization techniques.

Mannila J, Lehtonen M, Järvinen T, Jarho P.

J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Oct 25;810(2):283-90.

PMID:
15380726

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