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Items: 43

1.

Evaluating prognostic utility of preoperative Neutrophil to Lymphocyte Ratio and hsa-let-7g/c up-regulation in patients with urinary bladder cancer.

Boubaker NS, Gurtner A, Trabelsi N, Manni I, Said R, Ayed H, Ksentini M, Karray O, Saadi A, Essid MA, Blel A, Rommeni SR, Chebil M, Piaggio G, Ouerhani S.

Cancer Biomark. 2019 Oct 25. doi: 10.3233/CBM-190483. [Epub ahead of print]

PMID:
31683460
2.

Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4.

Lucà R, di Blasio G, Gallo D, Monteleone V, Manni I, Fici L, Buttarelli M, Ciolli G, Pellegrino M, Teveroni E, Maiullari S, Ciucci A, Apollo A, Mancini F, Gentileschi MP, Zannoni GF, Pontecorvi A, Scambia G, Moretti F.

Cancers (Basel). 2019 Sep 12;11(9). pii: E1349. doi: 10.3390/cancers11091349.

3.

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.

Mottini C, Tomihara H, Carrella D, Lamolinara A, Iezzi M, Huang JK, Amoreo CA, Buglioni S, Manni I, Robinson FS, Minelli R, Kang Y, Fleming JB, Kim MP, Bristow CA, Trisciuoglio D, Iuliano A, Del Bufalo D, Di Bernardo D, Melisi D, Draetta GF, Ciliberto G, Carugo A, Cardone L.

Cancer Res. 2019 Nov 1;79(21):5612-5625. doi: 10.1158/0008-5472.CAN-19-0187. Epub 2019 Sep 5.

PMID:
31492820
4.

Transgenic Animal Models to Visualize Cancer-Related Cellular Processes by Bioluminescence Imaging.

Manni I, de Latouliere L, Gurtner A, Piaggio G.

Front Pharmacol. 2019 Mar 15;10:235. doi: 10.3389/fphar.2019.00235. eCollection 2019. Review.

5.

Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies.

Rosati J, Ferrari D, Altieri F, Tardivo S, Ricciolini C, Fusilli C, Zalfa C, Profico DC, Pinos F, Bernardini L, Torres B, Manni I, Piaggio G, Binda E, Copetti M, Lamorte G, Mazza T, Carella M, Gelati M, Valente EM, Simeone A, Vescovi AL.

Cell Death Dis. 2018 Sep 17;9(10):937. doi: 10.1038/s41419-018-0990-2.

6.

Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits.

La Torre M, Merigliano C, Burla R, Mottini C, Zanetti G, Del Giudice S, Carcuro M, Virdia I, Bucciarelli E, Manni I, Vinciguerra GR, Piaggio G, Riminucci M, Cumano A, Bartolazzi A, Vernì F, Soddu S, Gatti M, Saggio I.

Aging Cell. 2018 Aug;17(4):e12730. doi: 10.1111/acel.12730. Epub 2018 Apr 10.

7.

The advanced glycation end-product Nϵ -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention.

Menini S, Iacobini C, de Latouliere L, Manni I, Ionta V, Blasetti Fantauzzi C, Pesce C, Cappello P, Novelli F, Piaggio G, Pugliese G.

J Pathol. 2018 Jun;245(2):197-208. doi: 10.1002/path.5072. Epub 2018 Apr 4.

8.

Radiolabeling of VEGF165 with 99mTc to evaluate VEGFR expression in tumor angiogenesis.

Galli F, Artico M, Taurone S, Manni I, Bianchi E, Piaggio G, Weintraub BD, Szkudlinski MW, Agostinelli E, Dierckx RAJO, Signore A.

Int J Oncol. 2017 Jun;50(6):2171-2179. doi: 10.3892/ijo.2017.3989. Epub 2017 May 8.

PMID:
28498441
9.

Monitoring the Response of Hyperbilirubinemia in the Mouse Brain by In Vivo Bioluminescence Imaging.

Manni I, Di Rocco G, Fusco S, Leone L, Barbati SA, Carapella CM, Grassi C, Piaggio G, Toietta G.

Int J Mol Sci. 2016 Dec 28;18(1). pii: E50. doi: 10.3390/ijms18010050.

10.

NF-Y in cancer: Impact on cell transformation of a gene essential for proliferation.

Gurtner A, Manni I, Piaggio G.

Biochim Biophys Acta Gene Regul Mech. 2017 May;1860(5):604-616. doi: 10.1016/j.bbagrm.2016.12.005. Epub 2016 Dec 9. Review.

PMID:
27939755
11.

The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferation.

Cicchillitti L, Manni I, Mancone C, Regazzo G, Spagnuolo M, Alonzi T, Carlomosti F, Dell'Anna ML, Dell'Omo G, Picardo M, Ciana P, Capogrossi MC, Tripodi M, Magenta A, Rizzo MG, Gurtner A, Piaggio G.

Oncotarget. 2017 Jan 10;8(2):2628-2646. doi: 10.18632/oncotarget.12914.

12.

Systemic distribution of single-walled carbon nanotubes in a novel model: alteration of biochemical parameters, metabolic functions, liver accumulation, and inflammation in vivo.

Principi E, Girardello R, Bruno A, Manni I, Gini E, Pagani A, Grimaldi A, Ivaldi F, Congiu T, De Stefano D, Piaggio G, de Eguileor M, Noonan DM, Albini A.

Int J Nanomedicine. 2016 Sep 1;11:4299-316. doi: 10.2147/IJN.S109950. eCollection 2016.

13.

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.

Carrella D, Manni I, Tumaini B, Dattilo R, Papaccio F, Mutarelli M, Sirci F, Amoreo CA, Mottolese M, Iezzi M, Ciolli L, Aria V, Bosotti R, Isacchi A, Loreni F, Bardelli A, Avvedimento VE, di Bernardo D, Cardone L.

Oncotarget. 2016 Sep 13;7(37):58743-58758. doi: 10.18632/oncotarget.11318.

14.

Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci.

Falcone E, Grandoni L, Garibaldi F, Manni I, Filligoi G, Piaggio G, Gurtner A.

PLoS One. 2016 Apr 15;11(4):e0153658. doi: 10.1371/journal.pone.0153658. eCollection 2016.

15.

Bioluminescence imaging of estrogen receptor activity during breast cancer progression.

Vantaggiato C, Dell'Omo G, Ramachandran B, Manni I, Radaelli E, Scanziani E, Piaggio G, Maggi A, Ciana P.

Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):32-41. eCollection 2016.

16.

Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model.

Mercurio L, Ajmone-Cat MA, Cecchetti S, Ricci A, Bozzuto G, Molinari A, Manni I, Pollo B, Scala S, Carpinelli G, Minghetti L.

J Exp Clin Cancer Res. 2016 Mar 25;35:55. doi: 10.1186/s13046-016-0326-y.

17.

A bioluminescent mouse model of proliferation to highlight early stages of pancreatic cancer: A suitable tool for preclinical studies.

de Latouliere L, Manni I, Iacobini C, Pugliese G, Grazi GL, Perri P, Cappello P, Novelli F, Menini S, Piaggio G.

Ann Anat. 2016 Sep;207:2-8. doi: 10.1016/j.aanat.2015.11.010. Epub 2015 Dec 15.

18.

Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapy.

Pellegrino M, Mancini F, Lucà R, Coletti A, Giacchè N, Manni I, Arisi I, Florenzano F, Teveroni E, Buttarelli M, Fici L, Brandi R, Bruno T, Fanciulli M, D'Onofrio M, Piaggio G, Pellicciari R, Pontecorvi A, Marine JC, Macchiarulo A, Moretti F.

Cancer Res. 2015 Nov 1;75(21):4560-72. doi: 10.1158/0008-5472.CAN-15-0439. Epub 2015 Sep 10.

19.

In Vivo Imaging of Natural Killer Cell Trafficking in Tumors.

Galli F, Rapisarda AS, Stabile H, Malviya G, Manni I, Bonanno E, Piaggio G, Gismondi A, Santoni A, Signore A.

J Nucl Med. 2015 Oct;56(10):1575-80. doi: 10.2967/jnumed.114.152918. Epub 2015 Aug 13.

20.

ATM kinase sustains HER2 tumorigenicity in breast cancer.

Stagni V, Manni I, Oropallo V, Mottolese M, Di Benedetto A, Piaggio G, Falcioni R, Giaccari D, Di Carlo S, Sperati F, Cencioni MT, Barilà D.

Nat Commun. 2015 Apr 16;6:6886. doi: 10.1038/ncomms7886.

PMID:
25881002
21.

In vivo imaging of cell proliferation for a dynamic, whole body, analysis of undesired drug effects.

Rizzi N, Manni I, Vantaggiato C, Delledonne GA, Gentileschi MP, Maggi A, Piaggio G, Ciana P.

Toxicol Sci. 2015 Jun;145(2):296-306. doi: 10.1093/toxsci/kfv056. Epub 2015 Mar 12.

PMID:
25766884
22.

(99m)Tc-labeled-rhTSH analogue (TR1401) for imaging poorly differentiated metastatic thyroid cancer.

Galli F, Manni I, Piaggio G, Balogh L, Weintraub BD, Szkudlinski MW, Fremont V, Dierckx RA, Signore A.

Thyroid. 2014 Aug;24(8):1297-308. doi: 10.1089/thy.2013.0429. Epub 2014 Jun 20.

23.

Dual promoter usage as regulatory mechanism of let-7c expression in leukemic and solid tumors.

Pelosi A, Careccia S, Sagrestani G, Nanni S, Manni I, Schinzari V, Martens JH, Farsetti A, Stunnenberg HG, Gentileschi MP, Del Bufalo D, De Maria R, Piaggio G, Rizzo MG.

Mol Cancer Res. 2014 Jun;12(6):878-89. doi: 10.1158/1541-7786.MCR-13-0410. Epub 2014 Mar 17.

24.

A nitric oxide-dependent cross-talk between class I and III histone deacetylases accelerates skin repair.

Spallotta F, Cencioni C, Straino S, Nanni S, Rosati J, Artuso S, Manni I, Colussi C, Piaggio G, Martelli F, Valente S, Mai A, Capogrossi MC, Farsetti A, Gaetano C.

J Biol Chem. 2013 Apr 19;288(16):11004-12. doi: 10.1074/jbc.M112.441816. Epub 2013 Mar 5.

25.

Immunotherapy in new pre-clinical models of HPV-associated oral cancers.

Paolini F, Massa S, Manni I, Franconi R, Venuti A.

Hum Vaccin Immunother. 2013 Mar;9(3):534-43. Epub 2013 Jan 7.

26.

Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals.

Goeman F, Manni I, Artuso S, Ramachandran B, Toietta G, Bossi G, Rando G, Cencioni C, Germoni S, Straino S, Capogrossi MC, Bacchetti S, Maggi A, Sacchi A, Ciana P, Piaggio G.

Mol Biol Cell. 2012 Apr;23(8):1467-74. doi: 10.1091/mbc.E12-01-0039. Epub 2012 Feb 29.

27.

Transcription factor NF-Y induces apoptosis in cells expressing wild-type p53 through E2F1 upregulation and p53 activation.

Gurtner A, Fuschi P, Martelli F, Manni I, Artuso S, Simonte G, Ambrosino V, Antonini A, Folgiero V, Falcioni R, Sacchi A, Piaggio G.

Cancer Res. 2010 Dec 1;70(23):9711-20. doi: 10.1158/0008-5472.CAN-10-0721. Epub 2010 Oct 15.

28.

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms.

Manni I, Artuso S, Careccia S, Rizzo MG, Baserga R, Piaggio G, Sacchi A.

FASEB J. 2009 Nov;23(11):3957-66. doi: 10.1096/fj.09-131847. Epub 2009 Jul 16.

PMID:
19608627
29.

Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity.

Manni I, Caretti G, Artuso S, Gurtner A, Emiliozzi V, Sacchi A, Mantovani R, Piaggio G.

Mol Biol Cell. 2008 Dec;19(12):5203-13. doi: 10.1091/mbc.E08-03-0295. Epub 2008 Sep 24.

30.

Cell cycle regulation of NF-YC nuclear localization.

Frontini M, Imbriano C, Manni I, Mantovani R.

Cell Cycle. 2004 Feb;3(2):217-22.

PMID:
14712092
31.

Requirement for down-regulation of the CCAAT-binding activity of the NF-Y transcription factor during skeletal muscle differentiation.

Gurtner A, Manni I, Fuschi P, Mantovani R, Guadagni F, Sacchi A, Piaggio G.

Mol Biol Cell. 2003 Jul;14(7):2706-15. Epub 2003 Apr 4.

32.

YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.

Jurchott K, Bergmann S, Stein U, Walther W, Janz M, Manni I, Piaggio G, Fietze E, Dietel M, Royer HD.

J Biol Chem. 2003 Jul 25;278(30):27988-96. Epub 2003 Apr 14.

33.

Mxi1 inhibits the proliferation of U87 glioma cells through down-regulation of cyclin B1 gene expression.

Manni I, Tunici P, Cirenei N, Albarosa R, Colombo BM, Roz L, Sacchi A, Piaggio G, Finocchiaro G.

Br J Cancer. 2002 Feb 1;86(3):477-84.

34.

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

D'Orazi G, Cecchinelli B, Bruno T, Manni I, Higashimoto Y, Saito S, Gostissa M, Coen S, Marchetti A, Del Sal G, Piaggio G, Fanciulli M, Appella E, Soddu S.

Nat Cell Biol. 2002 Jan;4(1):11-9.

PMID:
11780126
35.

The cyclin B1 gene is actively transcribed during mitosis in HeLa cells.

Sciortino S, Gurtner A, Manni I, Fontemaggi G, Dey A, Sacchi A, Ozato K, Piaggio G.

EMBO Rep. 2001 Nov;2(11):1018-23. Epub 2001 Oct 17.

36.

NF-Y mediates the transcriptional inhibition of the cyclin B1, cyclin B2, and cdc25C promoters upon induced G2 arrest.

Manni I, Mazzaro G, Gurtner A, Mantovani R, Haugwitz U, Krause K, Engeland K, Sacchi A, Soddu S, Piaggio G.

J Biol Chem. 2001 Feb 23;276(8):5570-6. Epub 2000 Nov 28.

37.

Down-regulation of cyclin B1 gene transcription in terminally differentiated skeletal muscle cells is associated with loss of functional CCAAT-binding NF-Y complex.

Farina A, Manni I, Fontemaggi G, Tiainen M, Cenciarelli C, Bellorini M, Mantovani R, Sacchi A, Piaggio G.

Oncogene. 1999 May 6;18(18):2818-27.

38.

Medullary thyroid carcinomas in transgenic mice expressing a Polyoma carboxyl-terminal truncated middle-T and wild type small-T antigens.

Felici A, Giorgio M, Krauzewicz N, Della Rocca C, Santoro M, Rovere P, Manni I, Amati P, Pozzi L.

Oncogene. 1999 Apr 8;18(14):2387-95.

39.

The cyclin B2 promoter depends on NF-Y, a trimer whose CCAAT-binding activity is cell-cycle regulated.

Bolognese F, Wasner M, Dohna CL, Gurtner A, Ronchi A, Muller H, Manni I, Mossner J, Piaggio G, Mantovani R, Engeland K.

Oncogene. 1999 Mar 11;18(10):1845-53.

40.

Wild-type p53-mediated down-modulation of interleukin 15 and interleukin 15 receptors in human rhabdomyosarcoma cells.

De Giovanni C, Nanni P, Sacchi A, Soddu S, Manni I, D'Orazi G, Bulfone-Paus S, Pohl T, Landuzzi L, Nicoletti G, Frabetti F, Rossi I, Lollini PL.

Br J Cancer. 1998 Dec;78(12):1541-6.

41.

The inhibition of cyclin B1 gene transcription in quiescent NIH3T3 cells is mediated by an E-box.

Farina A, Gaetano C, Crescenzi M, Puccini F, Manni I, Sacchi A, Piaggio G.

Oncogene. 1996 Sep 19;13(6):1287-96.

PMID:
8808703
42.

Structure and growth-dependent regulation of the human cyclin B1 promoter.

Piaggio G, Farina A, Perrotti D, Manni I, Fuschi P, Sacchi A, Gaetano C.

Exp Cell Res. 1995 Feb;216(2):396-402.

PMID:
7843284
43.

Retinoic acid and cAMP differentially regulate human chromogranin A promoter activity during differentiation of neuroblastoma cells.

Gaetano C, Manni I, Bossi G, Piaggio G, Soddu S, Farina A, Helman LJ, Sacchi A.

Eur J Cancer. 1995;31A(4):447-52.

PMID:
7576943

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