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Items: 1 to 50 of 157

1.

Interaction of isolated cross-linked short actin oligomers with the skeletal muscle myosin motor domain.

Qu Z, Fujita-Becker S, Ballweber E, Ince S, Herrmann C, Schröder RR, Mannherz HG.

FEBS J. 2018 May;285(9):1715-1729. doi: 10.1111/febs.14442. Epub 2018 Apr 16.

2.

VEGF Triggers the Activation of Cofilin and the Arp2/3 Complex within the Growth Cone.

Schlau M, Terheyden-Keighley D, Theis V, Mannherz HG, Theiss C.

Int J Mol Sci. 2018 Jan 27;19(2). pii: E384. doi: 10.3390/ijms19020384.

3.

Host DNases prevent vascular occlusion by neutrophil extracellular traps.

Jiménez-Alcázar M, Rangaswamy C, Panda R, Bitterling J, Simsek YJ, Long AT, Bilyy R, Krenn V, Renné C, Renné T, Kluge S, Panzer U, Mizuta R, Mannherz HG, Kitamura D, Herrmann M, Napirei M, Fuchs TA.

Science. 2017 Dec 1;358(6367):1202-1206. doi: 10.1126/science.aam8897.

PMID:
29191910
4.

Actin: Structure, Function, Dynamics, and Interactions with Bacterial Toxins.

Kühn S, Mannherz HG.

Curr Top Microbiol Immunol. 2017;399:1-34. doi: 10.1007/82_2016_45. Review.

PMID:
27848038
5.

Photorhabdus luminescens Toxins TccC3 and TccC5 Affect the Interaction of Actin with Actin-Binding Proteins Essential for Treadmilling.

Lang AE, Kühn S, Mannherz HG.

Curr Top Microbiol Immunol. 2017;399:53-67. doi: 10.1007/82_2016_43. Review.

PMID:
27757548
6.

Actin ADP-ribosylation at Threonine148 by Photorhabdus luminescens toxin TccC3 induces aggregation of intracellular F-actin.

Lang AE, Qu Z, Schwan C, Silvan U, Unger A, Schoenenberger CA, Aktories K, Mannherz HG.

Cell Microbiol. 2017 Jan;19(1). doi: 10.1111/cmi.12636. Epub 2016 Jul 15.

PMID:
27341322
7.

Contributions of the lower dimer to supramolecular actin patterning revealed by TIRF microscopy.

Silván U, Hyotyla J, Mannherz HG, Ringler P, Müller SA, Aebi U, Maier T, Schoenenberger CA.

J Struct Biol. 2016 Aug;195(2):159-166. doi: 10.1016/j.jsb.2016.05.008. Epub 2016 May 14.

PMID:
27189866
8.

Reelin and cofilin cooperate during the migration of cortical neurons: a quantitative morphological analysis.

Chai X, Zhao S, Fan L, Zhang W, Lu X, Shao H, Wang S, Song L, Failla AV, Zobiak B, Mannherz HG, Frotscher M.

Development. 2016 Mar 15;143(6):1029-40. doi: 10.1242/dev.134163. Epub 2016 Feb 18.

9.

Gelsolin interacts with LamR, hnRNP U, nestin, Arp3 and β-tubulin in human melanoma cells as revealed by immunoprecipitation and mass spectrometry.

Mazur AJ, Radaszkiewicz T, Makowiecka A, Malicka-Błaszkiewicz M, Mannherz HG, Nowak D.

Eur J Cell Biol. 2016 Jan;95(1):26-41. doi: 10.1016/j.ejcb.2015.11.001. Epub 2015 Nov 10.

PMID:
26598132
10.

Distinct actin oligomers modulate differently the activity of actin nucleators.

Qu Z, Silvan U, Jockusch BM, Aebi U, Schoenenberger CA, Mannherz HG.

FEBS J. 2015 Oct;282(19):3824-40. doi: 10.1111/febs.13381. Epub 2015 Aug 11.

11.

VEGF Signaling Regulates Cofilin and the Arp2/3-complex within the Axonal Growth Cone.

Dumpich M, Mannherz HG, Theiss C.

Curr Neurovasc Res. 2015;12(3):293-307. Review.

PMID:
26036972
12.

Translation elongation factor EF-Tu modulates filament formation of actin-like MreB protein in vitro.

Defeu Soufo HJ, Reimold C, Breddermann H, Mannherz HG, Graumann PL.

J Mol Biol. 2015 Apr 24;427(8):1715-27. doi: 10.1016/j.jmb.2015.01.025. Epub 2015 Feb 10.

13.

Distribution of formins in cardiac muscle: FHOD1 is a component of intercalated discs and costameres.

Al Haj A, Mazur AJ, Radaszkiewicz K, Radaszkiewicz T, Makowiecka A, Stopschinski BE, Schönichen A, Geyer M, Mannherz HG.

Eur J Cell Biol. 2015 Feb;94(2):101-13. doi: 10.1016/j.ejcb.2014.11.003. Epub 2014 Dec 12.

PMID:
25555464
14.

Impaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies.

Jiménez-Alcázar M, Napirei M, Panda R, Köhler EC, Kremer Hovinga JA, Mannherz HG, Peine S, Renné T, Lämmle B, Fuchs TA.

J Thromb Haemost. 2015 May;13(5):732-42. doi: 10.1111/jth.12796. Epub 2015 Apr 13.

15.

Molecular mechanisms of disease-related human β-actin mutations p.R183W and p.E364K.

Hundt N, Preller M, Swolski O, Ang AM, Mannherz HG, Manstein DJ, Müller M.

FEBS J. 2014 Dec;281(23):5279-91. doi: 10.1111/febs.13068. Epub 2014 Oct 13.

16.

Thymosin beta4 inhibits ADF/cofilin stimulated F-actin cycling and hela cell migration: reversal by active Arp2/3 complex.

Al Haj A, Mazur AJ, Buchmeier S, App C, Theiss C, Silvan U, Schoenenberger CA, Jockusch BM, Hannappel E, Weeds AG, Mannherz HG.

Cytoskeleton (Hoboken). 2014 Feb;71(2):95-107. doi: 10.1002/cm.21128. Epub 2013 Dec 31.

PMID:
24382810
17.

FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers.

Schönichen A, Mannherz HG, Behrmann E, Mazur AJ, Kühn S, Silván U, Schoenenberger CA, Fackler OT, Raunser S, Dehmelt L, Geyer M.

J Cell Sci. 2013 Apr 15;126(Pt 8):1891-901. doi: 10.1242/jcs.126706. Epub 2013 Feb 26.

18.

Identification of interaction partners of β-thymosins: application of thymosin β4 labeled by transglutaminase.

App C, Knop J, Mannherz HG, Hannappel E.

Ann N Y Acad Sci. 2012 Oct;1270:98-104. doi: 10.1111/j.1749-6632.2012.06658.x. Review.

PMID:
23050824
19.

Structure of the rigor actin-tropomyosin-myosin complex.

Behrmann E, Müller M, Penczek PA, Mannherz HG, Manstein DJ, Raunser S.

Cell. 2012 Jul 20;150(2):327-38. doi: 10.1016/j.cell.2012.05.037.

20.

Cofilin overexpression affects actin cytoskeleton organization and migration of human colon adenocarcinoma cells.

Popow-Woźniak A, Mazur AJ, Mannherz HG, Malicka-Błaszkiewicz M, Nowak D.

Histochem Cell Biol. 2012 Nov;138(5):725-36. doi: 10.1007/s00418-012-0988-2. Epub 2012 Jul 13.

21.

Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy.

Müller M, Mazur AJ, Behrmann E, Diensthuber RP, Radke MB, Qu Z, Littwitz C, Raunser S, Schoenenberger CA, Manstein DJ, Mannherz HG.

Cell Mol Life Sci. 2012 Oct;69(20):3457-79. doi: 10.1007/s00018-012-1030-5. Epub 2012 May 29.

PMID:
22643837
22.

Gelsolin affects the migratory ability of human colon adenocarcinoma and melanoma cells.

Litwin M, Nowak D, Mazur AJ, Baczyńska D, Mannherz HG, Malicka-Błaszkiewicz M.

Life Sci. 2012 Jun 6;90(21-22):851-61. doi: 10.1016/j.lfs.2012.03.039. Epub 2012 Apr 19.

PMID:
22552326
23.

Induction of fat cell necrosis in human fat tissue after treatment with phosphatidylcholine and deoxycholate.

Bechara FG, Mannherz HG, Jacob M, Mazur AJ, Sand M, Altmeyer P, Hoffmann K.

J Eur Acad Dermatol Venereol. 2012 Feb;26(2):180-5. doi: 10.1111/j.1468-3083.2011.04028.x. Epub 2011 Mar 9.

PMID:
22280507
24.

An antiparallel actin dimer is associated with the endocytic pathway in mammalian cells.

Silván U, Boiteux C, Sütterlin R, Schroeder U, Mannherz HG, Jockusch BM, Bernèche S, Aebi U, Schoenenberger CA.

J Struct Biol. 2012 Jan;177(1):70-80. doi: 10.1016/j.jsb.2011.09.010. Epub 2011 Sep 25.

PMID:
21970948
25.

Actin: from structural plasticity to functional diversity.

Schoenenberger CA, Mannherz HG, Jockusch BM.

Eur J Cell Biol. 2011 Oct;90(10):797-804. doi: 10.1016/j.ejcb.2011.05.002. Epub 2011 Aug 4. Review.

PMID:
21820202
26.

Actin as target for modification by bacterial protein toxins.

Aktories K, Lang AE, Schwan C, Mannherz HG.

FEBS J. 2011 Dec;278(23):4526-43. doi: 10.1111/j.1742-4658.2011.08113.x. Epub 2011 May 4. Review.

27.

Actin filament bundling and different nucleating effects of mouse Diaphanous-related formin FH2 domains on actin/ADF and actin/cofilin complexes.

Machaidze G, Sokoll A, Shimada A, Lustig A, Mazur A, Wittinghofer A, Aebi U, Mannherz HG.

J Mol Biol. 2010 Nov 5;403(4):529-45. doi: 10.1016/j.jmb.2010.09.017. Epub 2010 Oct 1.

PMID:
20869367
28.

Morphological characterization of periodontium-derived human stem cells.

Arnold WH, Becher S, Dannan A, Widera D, Dittmar T, Jacob M, Mannherz HG, Dittmar T, Kaltschmidt B, Kaltschmidt C, Grimm WD.

Ann Anat. 2010 Aug 20;192(4):215-9. doi: 10.1016/j.aanat.2010.05.004. Epub 2010 Jun 11.

PMID:
20591640
29.

Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potential.

Nowak D, Mazur AJ, Popow-Woźniak A, Radwańska A, Mannherz HG, Malicka-Błaszkiewicz M.

Eur J Histochem. 2010 Apr 13;54(2):e14.

30.

Repolymerization of actin from actin:thymosin beta4 complex induced by diaphanous related formins and gelsolin.

Mannherz HG, Mazur AJ, Jockusch B.

Ann N Y Acad Sci. 2010 Apr;1194:36-43. doi: 10.1111/j.1749-6632.2010.05467.x. Review.

PMID:
20536448
31.

Photorhabdus luminescens toxins ADP-ribosylate actin and RhoA to force actin clustering.

Lang AE, Schmidt G, Schlosser A, Hey TD, Larrinua IM, Sheets JJ, Mannherz HG, Aktories K.

Science. 2010 Feb 26;327(5969):1139-42. doi: 10.1126/science.1184557.

32.

A case of persistent left and absent right superior caval vein: An anatomical and embryological perspective.

Jacob M, Sokoll A, Mannherz HG.

Clin Anat. 2010 Apr;23(3):277-86. doi: 10.1002/ca.20945.

PMID:
20169608
33.

Modulation of actin filament dynamics by actin-binding proteins residing in lamellipodia.

Mazur AJ, Gremm D, Dansranjavin T, Litwin M, Jockusch BM, Wegner A, Weeds AG, Mannherz HG.

Eur J Cell Biol. 2010 May;89(5):402-13. doi: 10.1016/j.ejcb.2009.10.017. Epub 2010 Feb 4.

PMID:
20133009
34.

Gelsolin in human colon adenocarcinoma cells with different metastatic potential.

Litwin M, Mazur AJ, Nowak D, Mannherz HG, Malicka-Błaszkiewicz M.

Acta Biochim Pol. 2009;56(4):739-43. Epub 2009 Dec 4.

35.

The beta-thymosins: intracellular and extracellular activities of a versatile actin binding protein family.

Mannherz HG, Hannappel E.

Cell Motil Cytoskeleton. 2009 Oct;66(10):839-51. doi: 10.1002/cm.20371. Review.

PMID:
19405116
36.

Methotrexate induces apoptosis in CaSki and NRK cells and influences the organization of their actin cytoskeleton.

Mazur AJ, Nowak D, Mannherz HG, Malicka-Błaszkiewicz M.

Eur J Pharmacol. 2009 Jun 24;613(1-3):24-33. doi: 10.1016/j.ejphar.2009.04.020. Epub 2009 Apr 19.

PMID:
19383496
37.

Murine serum nucleases--contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1l3).

Napirei M, Ludwig S, Mezrhab J, Klöckl T, Mannherz HG.

FEBS J. 2009 Feb;276(4):1059-73. doi: 10.1111/j.1742-4658.2008.06849.x. Epub 2009 Jan 16.

38.

Murine serum deoxyribonuclease 1 (Dnase1) activity partly originates from the liver.

Ludwig S, Mannherz HG, Schmitt S, Schäffer M, Zentgraf H, Napirei M.

Int J Biochem Cell Biol. 2009 May;41(5):1079-93. doi: 10.1016/j.biocel.2008.09.030. Epub 2008 Oct 14.

PMID:
18973821
39.

Cross-linked long-pitch actin dimer forms stoichiometric complexes with gelsolin segment 1 and/or deoxyribonuclease I that nonproductively interact with myosin subfragment 1.

Mannherz HG, Ballweber E, Hegyi G, Goody RS.

Biochemistry. 2008 Sep 2;47(35):9335-43. doi: 10.1021/bi800410z. Epub 2008 Aug 12.

PMID:
18693756
40.

Arp2/3 complex interactions and actin network turnover in lamellipodia.

Lai FP, Szczodrak M, Block J, Faix J, Breitsprecher D, Mannherz HG, Stradal TE, Dunn GA, Small JV, Rottner K.

EMBO J. 2008 Apr 9;27(7):982-92. doi: 10.1038/emboj.2008.34. Epub 2008 Feb 28.

41.
42.

Inhibition of deoxyribonuclease I by actin is to protect cells from premature cell death.

Eulitz D, Mannherz HG.

Apoptosis. 2007 Aug;12(8):1511-21.

PMID:
17468836
43.

Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin.

Mannherz HG, Ballweber E, Galla M, Villard S, Granier C, Steegborn C, Schmidtmann A, Jaquet K, Pope B, Weeds AG.

J Mol Biol. 2007 Feb 23;366(3):745-55. Epub 2006 Dec 15.

PMID:
17196218
44.

Changes in gap junction organization and decreased coupling during induced apoptosis in lens epithelial and NIH-3T3 cells.

Theiss C, Mazur A, Meller K, Mannherz HG.

Exp Cell Res. 2007 Jan 1;313(1):38-52. Epub 2006 Oct 13.

PMID:
17123514
45.

Dual effects of staurosporine on A431 and NRK cells: microfilament disassembly and uncoordinated lamellipodial activity followed by cell death.

Mannherz HG, Gonsior SM, Wu X, Polzar B, Pope BJ, Wartosch L, Weeds AG.

Eur J Cell Biol. 2006 Aug;85(8):785-802. Epub 2006 May 11.

PMID:
16697076
46.

Deoxyribonuclease 1 aggravates acetaminophen-induced liver necrosis in male CD-1 mice.

Napirei M, Basnakian AG, Apostolov EO, Mannherz HG.

Hepatology. 2006 Feb;43(2):297-305.

PMID:
16440339
47.

Systemic lupus-erythematosus: deoxyribonuclease 1 in necrotic chromatin disposal.

Napirei M, Gültekin A, Kloeckl T, Möröy T, Frostegård J, Mannherz HG.

Int J Biochem Cell Biol. 2006 Mar;38(3):297-306. Epub 2005 Nov 28.

PMID:
16352456
48.

Activated cofilin colocalises with Arp2/3 complex in apoptotic blebs during programmed cell death.

Mannherz HG, Gonsior SM, Gremm D, Wu X, Pope BJ, Weeds AG.

Eur J Cell Biol. 2005 Apr;84(4):503-15.

PMID:
15900709
49.

Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3).

Napirei M, Wulf S, Eulitz D, Mannherz HG, Kloeckl T.

Biochem J. 2005 Jul 15;389(Pt 2):355-64.

50.

Cisplatin nephrotoxicity is mediated by deoxyribonuclease I.

Basnakian AG, Apostolov EO, Yin X, Napirei M, Mannherz HG, Shah SV.

J Am Soc Nephrol. 2005 Mar;16(3):697-702. Epub 2005 Jan 12.

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