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Items: 1 to 50 of 106

1.

Comparative Anatomy of the Mammalian Corneal Subbasal Nerve Plexus.

Marfurt C, Anokwute MC, Fetcko K, Mahony-Perez E, Farooq H, Ross E, Baumanis MM, Weinberg RL, McCarron ME, Mankowski JL.

Invest Ophthalmol Vis Sci. 2019 Dec 2;60(15):4972-4984. doi: 10.1167/iovs.19-28519.

2.

Brain macrophages harbor latent, infectious simian immunodeficiency virus.

Abreu C, Shirk EN, Queen SE, Beck SE, Mangus LM, Pate KAM, Mankowski JL, Gama L, Clements JE.

AIDS. 2019 Dec 1;33 Suppl 2:S181-S188. doi: 10.1097/QAD.0000000000002269.

PMID:
31789817
3.

Myeloid and CD4 T Cells Comprise the Latent Reservoir in Antiretroviral Therapy-Suppressed SIVmac251-Infected Macaques.

Abreu CM, Veenhuis RT, Avalos CR, Graham S, Parrilla DR, Ferreira EA, Queen SE, Shirk EN, Bullock BT, Li M, Metcalf Pate KA, Beck SE, Mangus LM, Mankowski JL, Mac Gabhann F, O'Connor SL, Gama L, Clements JE.

mBio. 2019 Aug 20;10(4). pii: e01659-19. doi: 10.1128/mBio.01659-19.

4.

The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.

Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DN, Seydi M, Gottlieb GS, Okoye AA, Del Prete GQ, Picker LJ, Mankowski JL, Lifson JD, Siliciano JD, Laird GM, Barouch DH, Clements JE, Siliciano RF.

Cell Host Microbe. 2019 Jul 10;26(1):73-85.e4. doi: 10.1016/j.chom.2019.06.005.

PMID:
31295427
5.

Infectious Virus Persists in CD4+ T Cells and Macrophages in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques.

Abreu CM, Veenhuis RT, Avalos CR, Graham S, Queen SE, Shirk EN, Bullock BT, Li M, Metcalf Pate KA, Beck SE, Mangus LM, Mankowski JL, Clements JE, Gama L.

J Virol. 2019 Jul 17;93(15). pii: e00065-19. doi: 10.1128/JVI.00065-19. Print 2019 Aug 1.

6.

SIV-Induced Immune Activation and Metabolic Alterations in the Dorsal Root Ganglia During Acute Infection.

Mangus LM, Weinberg RL, Knight AC, Queen SE, Adams RJ, Mankowski JL.

J Neuropathol Exp Neurol. 2019 Jan 1;78(1):78-87. doi: 10.1093/jnen/nly111.

7.

A Quantitative Approach to SIV Functional Latency in Brain Macrophages.

Abreu C, Shirk EN, Queen SE, Mankowski JL, Gama L, Clements JE.

J Neuroimmune Pharmacol. 2019 Mar;14(1):23-32. doi: 10.1007/s11481-018-9803-8. Epub 2018 Aug 30. Review.

PMID:
30167896
8.

SIV Latency in Macrophages in the CNS.

Gama L, Abreu C, Shirk EN, Queen SE, Beck SE, Metcalf Pate KA, Bullock BT, Zink MC, Mankowski JL, Clements JE.

Curr Top Microbiol Immunol. 2018;417:111-130. doi: 10.1007/82_2018_89. Review.

9.

Increased Microglial CSF1R Expression in the SIV/Macaque Model of HIV CNS Disease.

Knight AC, Brill SA, Queen SE, Tarwater PM, Mankowski JL.

J Neuropathol Exp Neurol. 2018 Mar 1;77(3):199-206. doi: 10.1093/jnen/nlx115.

10.

Lymphocyte-Dominant Encephalitis and Meningitis in Simian Immunodeficiency Virus-Infected Macaques Receiving Antiretroviral Therapy.

Mangus LM, Beck SE, Queen SE, Brill SA, Shirk EN, Metcalf Pate KA, Muth DC, Adams RJ, Gama L, Clements JE, Mankowski JL.

Am J Pathol. 2018 Jan;188(1):125-134. doi: 10.1016/j.ajpath.2017.08.035. Epub 2017 Dec 8.

11.

An SIV/macaque model targeted to study HIV-associated neurocognitive disorders.

Beck SE, Queen SE, Metcalf Pate KA, Mangus LM, Abreu CM, Gama L, Witwer KW, Adams RJ, Zink MC, Clements JE, Mankowski JL.

J Neurovirol. 2018 Apr;24(2):204-212. doi: 10.1007/s13365-017-0582-4. Epub 2017 Oct 3. Review.

12.

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir.

Avalos CR, Abreu CM, Queen SE, Li M, Price S, Shirk EN, Engle EL, Forsyth E, Bullock BT, Mac Gabhann F, Wietgrefe SW, Haase AT, Zink MC, Mankowski JL, Clements JE, Gama L.

mBio. 2017 Aug 15;8(4). pii: e01186-17. doi: 10.1128/mBio.01186-17.

13.

Genetic Characterization of a Captive Colony of Pigtailed Macaques (Macaca nemestrina).

Zhang X, Kanthaswamy S, Trask JS, Ng J, Oldt RF, Mankowski JL, Adams RJ, Smith DG.

J Am Assoc Lab Anim Sci. 2017 Jul 1;56(4):390-395.

14.

Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves.

Klein AH, Vyshnevska A, Hartke TV, De Col R, Mankowski JL, Turnquist B, Bosmans F, Reeh PW, Schmelz M, Carr RW, Ringkamp M.

J Neurosci. 2017 May 17;37(20):5204-5214. doi: 10.1523/JNEUROSCI.3799-16.2017. Epub 2017 Apr 27.

15.

HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.

Gannon PJ, Akay-Espinoza C, Yee AC, Briand LA, Erickson MA, Gelman BB, Gao Y, Haughey NJ, Zink MC, Clements JE, Kim NS, Van De Walle G, Jensen BK, Vassar R, Pierce RC, Gill AJ, Kolson DL, Diehl JA, Mankowski JL, Jordan-Sciutto KL.

Am J Pathol. 2017 Jan;187(1):91-109. doi: 10.1016/j.ajpath.2016.09.006.

16.

Splenic Damage during SIV Infection: Role of T-Cell Depletion and Macrophage Polarization and Infection.

Williams DW, Engle EL, Shirk EN, Queen SE, Gama L, Mankowski JL, Zink MC, Clements JE.

Am J Pathol. 2016 Aug;186(8):2068-2087. doi: 10.1016/j.ajpath.2016.03.019. Epub 2016 Jun 18.

17.

Tracking Epidermal Nerve Fiber Changes in Asian Macaques: Tools and Techniques for Quantitative Assessment.

Mangus LM, Dorsey JL, Weinberg RL, Ebenezer GJ, Hauer P, Laast VA, Mankowski JL.

Toxicol Pathol. 2016 Aug;44(6):904-12. doi: 10.1177/0192623316650286. Epub 2016 May 27.

18.

HIV-associated neurocognitive disorder - pathogenesis and prospects for treatment.

Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC.

Nat Rev Neurol. 2016 May;12(5):309. doi: 10.1038/nrneurol.2016.53. Epub 2016 Apr 15. No abstract available.

19.

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques.

Avalos CR, Price SL, Forsyth ER, Pin JN, Shirk EN, Bullock BT, Queen SE, Li M, Gellerup D, O'Connor SL, Zink MC, Mankowski JL, Gama L, Clements JE.

J Virol. 2016 May 27;90(12):5643-5656. doi: 10.1128/JVI.00290-16. Print 2016 Jun 15.

20.

RETROSPECTIVE REVIEW OF MORTALITY IN GIANT PACIFIC OCTOPUS (ENTEROCTOPUS DOFLEINI).

Seeley KE, Clayton LA, Hadfield CA, Muth D, Mankowski JL, Kelly KM.

J Zoo Wildl Med. 2016 Mar;47(1):271-4. doi: 10.1638/2014-0134.1.

PMID:
27010286
21.

RANAVIRUS EPIZOOTIC IN CAPTIVE EASTERN BOX TURTLES (TERRAPENE CAROLINA CAROLINA) WITH CONCURRENT HERPESVIRUS AND MYCOPLASMA INFECTION: MANAGEMENT AND MONITORING.

Sim RR, Allender MC, Crawford LK, Wack AN, Murphy KJ, Mankowski JL, Bronson E.

J Zoo Wildl Med. 2016 Mar;47(1):256-70. doi: 10.1638/2015-0048.1.

PMID:
27010285
22.

HIV-associated neurocognitive disorder--pathogenesis and prospects for treatment.

Saylor D, Dickens AM, Sacktor N, Haughey N, Slusher B, Pletnikov M, Mankowski JL, Brown A, Volsky DJ, McArthur JC.

Nat Rev Neurol. 2016 Apr;12(4):234-48. doi: 10.1038/nrneurol.2016.27. Epub 2016 Mar 11. Review. Erratum in: Nat Rev Neurol. 2016 May;12(5):309.

23.

Central nervous system-specific consequences of simian immunodeficiency virus Gag escape from major histocompatibility complex class I-mediated control.

Beck SE, Queen SE, Viscidi R, Johnson D, Kent SJ, Adams RJ, Tarwater PM, Mankowski JL.

J Neurovirol. 2016 Aug;22(4):498-507. doi: 10.1007/s13365-015-0420-5. Epub 2016 Jan 4.

24.

Persistent Peripheral Nervous System Damage in Simian Immunodeficiency Virus-Infected Macaques Receiving Antiretroviral Therapy.

Dorsey JL, Mangus LM, Hauer P, Ebenezer GJ, Queen SE, Laast VA, Adams RJ, Mankowski JL.

J Neuropathol Exp Neurol. 2015 Nov;74(11):1053-60. doi: 10.1097/NEN.0000000000000249.

25.

Bone Disease in the Common Marmoset: Radiographic and Histological Findings.

Olson EJ, Shaw GC, Hutchinson EK, Schultz-Darken N, Bolton ID, Parker JB, Morrison JM, Baxter VK, Pate KA, Mankowski JL, Carlson CS.

Vet Pathol. 2015 Sep;52(5):883-93. doi: 10.1177/0300985815589354. Epub 2015 Jun 15.

PMID:
26077785
26.

Neurocognitive dysfunction and pharmacological intervention using guanfacine in a rhesus macaque model of self-injurious behavior.

Freeman ZT, Rice KA, Soto PL, Pate KA, Weed MR, Ator NA, DeLeon IG, Wong DF, Zhou Y, Mankowski JL, Zink MC, Adams RJ, Hutchinson EK.

Transl Psychiatry. 2015 May 19;5:e567. doi: 10.1038/tp.2015.61.

27.

A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads.

Metcalf Pate KA, Pohlmeyer CW, Walker-Sperling VE, Foote JB, Najarro KM, Cryer CG, Salgado M, Gama L, Engle EL, Shirk EN, Queen SE, Chioma S, Vermillion MS, Bullock B, Li M, Lyons CE, Adams RJ, Zink MC, Clements JE, Mankowski JL, Blankson JN.

J Infect Dis. 2015 Nov 1;212(9):1387-96. doi: 10.1093/infdis/jiv230. Epub 2015 Apr 15.

28.

Paving the path to HIV neurotherapy: Predicting SIV CNS disease.

Beck SE, Queen SE, Witwer KW, Metcalf Pate KA, Mangus LM, Gama L, Adams RJ, Clements JE, Christine Zink M, Mankowski JL.

Eur J Pharmacol. 2015 Jul 15;759:303-12. doi: 10.1016/j.ejphar.2015.03.018. Epub 2015 Mar 24. Review.

29.

HIV eradication symposium: will the brain be left behind?

Brew BJ, Robertson K, Wright EJ, Churchill M, Crowe SM, Cysique LA, Deeks S, Garcia JV, Gelman B, Gray LR, Johnson T, Joseph J, Margolis DM, Mankowski JL, Spencer B.

J Neurovirol. 2015 Jun;21(3):322-34. doi: 10.1007/s13365-015-0322-6. Epub 2015 Mar 7.

30.

Macaque species susceptibility to simian immunodeficiency virus: increased incidence of SIV central nervous system disease in pigtailed macaques versus rhesus macaques.

Beck SE, Kelly KM, Queen SE, Adams RJ, Zink MC, Tarwater PM, Mankowski JL.

J Neurovirol. 2015 Apr;21(2):148-58. doi: 10.1007/s13365-015-0313-7. Epub 2015 Feb 12.

PMID:
25672885
31.

Constitutive BDNF/TrkB signaling is required for normal cardiac contraction and relaxation.

Feng N, Huke S, Zhu G, Tocchetti CG, Shi S, Aiba T, Kaludercic N, Hoover DB, Beck SE, Mankowski JL, Tomaselli GF, Bers DM, Kass DA, Paolocci N.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1880-5. doi: 10.1073/pnas.1417949112. Epub 2015 Jan 12. Erratum in: Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1691.

32.

Neuroinflammation and virus replication in the spinal cord of simian immunodeficiency virus-infected macaques.

Mangus LM, Dorsey JL, Laast VA, Hauer P, Queen SE, Adams RJ, McArthur JC, Mankowski JL.

J Neuropathol Exp Neurol. 2015 Jan;74(1):38-47. doi: 10.1097/NEN.0000000000000148.

33.

Combination fluconazole/paroxetine treatment is neuroprotective despite ongoing neuroinflammation and viral replication in an SIV model of HIV neurological disease.

Meulendyke KA, Queen SE, Engle EL, Shirk EN, Liu J, Steiner JP, Nath A, Tarwater PM, Graham DR, Mankowski JL, Zink MC.

J Neurovirol. 2014 Dec;20(6):591-602. doi: 10.1007/s13365-014-0283-1. Epub 2014 Sep 17.

34.

Fusarium solani species complex associated with carapace lesions and branchitis in captive American horseshoe crabs Limulus polyphemus.

Tuxbury KA, Shaw GC, Montali RJ, Clayton LA, Kwiatkowski NP, Dykstra MJ, Mankowski JL.

Dis Aquat Organ. 2014 Jul 3;109(3):223-30. doi: 10.3354/dao02764.

PMID:
24991848
35.

Loss of corneal sensory nerve fibers in SIV-infected macaques: an alternate approach to investigate HIV-induced PNS damage.

Dorsey JL, Mangus LM, Oakley JD, Beck SE, Kelly KM, Queen SE, Metcalf Pate KA, Adams RJ, Marfurt CF, Mankowski JL.

Am J Pathol. 2014 Jun;184(6):1652-9. doi: 10.1016/j.ajpath.2014.02.009. Epub 2014 May 12.

36.

TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages.

Witwer KW, Gama L, Mankowski JL, Zink MC, Clements JE.

AIDS Res Hum Retroviruses. 2014 Apr;30(4):333-4. doi: 10.1089/aid.2014.0029. No abstract available.

37.

CCR5 inhibition prevents cardiac dysfunction in the SIV/macaque model of HIV.

Kelly KM, Tocchetti CG, Lyashkov A, Tarwater PM, Bedja D, Graham DR, Beck SE, Metcalf Pate KA, Queen SE, Adams RJ, Paolocci N, Mankowski JL.

J Am Heart Assoc. 2014 Apr 2;3(2):e000874. doi: 10.1161/JAHA.114.000874.

38.

Unraveling the pathogenesis of HIV peripheral neuropathy: insights from a simian immunodeficiency virus macaque model.

Mangus LM, Dorsey JL, Laast VA, Ringkamp M, Ebenezer GJ, Hauer P, Mankowski JL.

ILAR J. 2014;54(3):296-303. doi: 10.1093/ilar/ilt047. Review.

39.

Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset.

Baxter VK, Shaw GC, Sotuyo NP, Carlson CS, Olson EJ, Zink MC, Mankowski JL, Adams RJ, Hutchinson EK, Metcalf Pate KA.

PLoS One. 2013 Dec 6;8(12):e82747. doi: 10.1371/journal.pone.0082747. eCollection 2013.

40.

TGFβ-Mediated Downregulation of Thrombopoietin Is Associated With Platelet Decline in Asymptomatic SIV Infection.

Metcalf Pate KA, Lyons CE, Dorsey JL, Queen SE, Adams RJ, Morrell CN, Mankowski JL.

J Acquir Immune Defic Syndr. 2014 Apr 15;65(5):510-6. doi: 10.1097/QAI.0000000000000048.

41.

Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain.

Kelly KM, Beck SE, Metcalf Pate KA, Queen SE, Dorsey JL, Adams RJ, Avery LB, Hubbard W, Tarwater PM, Mankowski JL.

AIDS. 2013 Nov 28;27(18):F21-8. doi: 10.1097/QAD.0000000000000074.

42.

14-3-3 Protein in CSF reflects SIV-mediated pre-synaptic damage.

Helke KL, Queen SE, Mankowski JL.

Curr HIV Res. 2013 Jun;11(4):281-7.

PMID:
24016180
43.

Platelet activation and platelet-monocyte aggregate formation contribute to decreased platelet count during acute simian immunodeficiency virus infection in pig-tailed macaques.

Metcalf Pate KA, Lyons CE, Dorsey JL, Shirk EN, Queen SE, Adams RJ, Gama L, Morrell CN, Mankowski JL.

J Infect Dis. 2013 Sep;208(6):874-83. doi: 10.1093/infdis/jit278. Epub 2013 Jul 11.

44.

Meeting report: Emerging respiratory viral infections and nonhuman primate case reports.

Sasseville VG, Mankowski JL, Baldessari A, Harbison C, Laing S, Kaliyaperumal S, Mätz-Rensing K, Miller AD, Schmidt LD, Kaplan-Kees J, Dick EJ Jr, Reader JR, Liu D, Crawford LK, Lane JH, Corner SM, Pardo ID, Evans MG, Murnane R, Terio KA.

Vet Pathol. 2013 Nov;50(6):1145-53. doi: 10.1177/0300985813495898. Epub 2013 Jul 9.

PMID:
23839235
45.

Mycobacterium abscessus pneumonia in an Atlantic bottlenose dolphin (Tursiops truncatus).

Clayton LA, Stamper MA, Whitaker BR, Hadfield CA, Simons B, Mankowski JL.

J Zoo Wildl Med. 2012 Dec;43(4):961-5.

46.

Meeting report: Spontaneous lesions and diseases in wild, captive-bred, and zoo-housed nonhuman primates and in nonhuman primate species used in drug safety studies.

Sasseville VG, Mansfield KG, Mankowski JL, Tremblay C, Terio KA, Mätz-Rensing K, Gruber-Dujardin E, Delaney MA, Schmidt LD, Liu D, Markovits JE, Owston M, Harbison C, Shanmukhappa S, Miller AD, Kaliyaperumal S, Assaf BT, Kattenhorn L, Macri SC, Simmons HA, Baldessari A, Sharma P, Courtney C, Bradley A, Cline JM, Reindel JF, Hutto DL, Montali RJ, Lowenstine LJ.

Vet Pathol. 2012 Nov;49(6):1057-69. doi: 10.1177/0300985812461655.

47.

HIV and SIV Associated Thrombocytopenia: An Expanding Role for Platelets in the Pathogenesis of HIV.

Metcalf Pate KA, Mankowski JL.

Drug Discov Today Dis Mech. 2011 Summer;8(1-2):e25-e32. Epub 2011 Nov 9.

48.

SIV-induced impairment of neurovascular repair: a potential role for VEGF.

Ebenezer GJ, McArthur JC, Polydefkis M, Dorsey JL, O'Donnell R, Hauer P, Adams RJ, Mankowski JL.

J Neurovirol. 2012 Jun;18(3):222-30. doi: 10.1007/s13365-012-0102-5. Epub 2012 May 2.

49.

Diastolic dysfunction is associated with myocardial viral load in simian immunodeficiency virus-infected macaques.

Kelly KM, Tarwater PM, Karper JM, Bedja D, Queen SE, Tunin RS, Adams RJ, Kass DA, Mankowski JL.

AIDS. 2012 Apr 24;26(7):815-23. doi: 10.1097/QAD.0b013e3283518f01.

PMID:
22301409
50.

Macrophage-mediated dorsal root ganglion damage precedes altered nerve conduction in SIV-infected macaques.

Laast VA, Shim B, Johanek LM, Dorsey JL, Hauer PE, Tarwater PM, Adams RJ, Pardo CA, McArthur JC, Ringkamp M, Mankowski JL.

Am J Pathol. 2011 Nov;179(5):2337-45. doi: 10.1016/j.ajpath.2011.07.047. Epub 2011 Sep 13.

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