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Items: 9

1.

Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.

Ekins S, Mankowski DC, Hoover DJ, Lawton MP, Treadway JL, Harwood HJ Jr.

Drug Metab Dispos. 2007 Mar;35(3):493-500. Epub 2006 Dec 28. Erratum in: Drug Metab Dispos. 2007 Jul;35(7):1246.

2.

Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.

Harwood HJ Jr, Petras SF, Hoover DJ, Mankowski DC, Soliman VF, Sugarman ED, Hulin B, Kwon Y, Gibbs EM, Mayne JT, Treadway JL.

J Lipid Res. 2005 Mar;46(3):547-63. Epub 2004 Dec 16.

3.

Prediction of human drug metabolizing enzyme induction.

Mankowski DC, Ekins S.

Curr Drug Metab. 2003 Oct;4(5):381-91. Review.

PMID:
14529370
4.

Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates.

Mankowski DC, Lawton MP, Ekins S.

Xenobiotica. 2000 Aug;30(8):745-54.

PMID:
11037108
5.

(R)-, (S)-, and racemic fluoxetine N-demethylation by human cytochrome P450 enzymes.

Margolis JM, O'Donnell JP, Mankowski DC, Ekins S, Obach RS.

Drug Metab Dispos. 2000 Oct;28(10):1187-91.

6.

Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver.

Mankowski DC, Laddison KJ, Christopherson PA, Ekins S, Tweedie DJ, Lawton MP.

Arch Biochem Biophys. 1999 Dec 1;372(1):189-96.

PMID:
10562433
7.
8.

Evidence suggesting the 58-kDa acetaminophen binding protein is a preferential target for acetaminophen electrophile.

Hoivik DJ, Manautou JE, Tveit A, Mankowski DC, Khairallah EA, Cohen SD.

Fundam Appl Toxicol. 1996 Jul;32(1):79-86.

PMID:
8812234
9.

Induction of cyp2e-1 protein in mouse colon.

Rosenberg DW, Mankowski DC.

Carcinogenesis. 1994 Jan;15(1):73-8.

PMID:
8293551

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