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Items: 45


Training for a First-Time Marathon Reverses Age-Related Aortic Stiffening.

Bhuva AN, D'Silva A, Torlasco C, Jones S, Nadarajan N, Van Zalen J, Chaturvedi N, Lloyd G, Sharma S, Moon JC, Hughes AD, Manisty CH.

J Am Coll Cardiol. 2020 Jan 7;75(1):60-71. doi: 10.1016/j.jacc.2019.10.045.


Making MRI available for patients with cardiac implantable electronic devices: growing need and barriers to change.

Bhuva AN, Moralee R, Moon JC, Manisty CH.

Eur Radiol. 2020 Mar;30(3):1378-1384. doi: 10.1007/s00330-019-06449-5. Epub 2019 Nov 27. Review.


A Multicenter, Scan-Rescan, Human and Machine Learning CMR Study to Test Generalizability and Precision in Imaging Biomarker Analysis.

Bhuva AN, Bai W, Lau C, Davies RH, Ye Y, Bulluck H, McAlindon E, Culotta V, Swoboda PP, Captur G, Treibel TA, Augusto JB, Knott KD, Seraphim A, Cole GD, Petersen SE, Edwards NC, Greenwood JP, Bucciarelli-Ducci C, Hughes AD, Rueckert D, Moon JC, Manisty CH.

Circ Cardiovasc Imaging. 2019 Oct;12(10):e009214. doi: 10.1161/CIRCIMAGING.119.009214. Epub 2019 Sep 24.


Non-invasive assessment of ventriculo-arterial coupling using aortic wave intensity analysis combining central blood pressure and phase-contrast cardiovascular magnetic resonance.

Bhuva AN, D'Silva A, Torlasco C, Nadarajan N, Jones S, Boubertakh R, Van Zalen J, Scully P, Knott K, Benedetti G, Augusto JB, Bastiaenen R, Lloyd G, Sharma S, Moon JC, Parker KH, Manisty CH, Hughes AD.

Eur Heart J Cardiovasc Imaging. 2019 Sep 9. pii: jez227. doi: 10.1093/ehjci/jez227. [Epub ahead of print]


Advanced Imaging Modalities to Monitor for Cardiotoxicity.

Seraphim A, Westwood M, Bhuva AN, Crake T, Moon JC, Menezes LJ, Lloyd G, Ghosh AK, Slater S, Oakervee H, Manisty CH.

Curr Treat Options Oncol. 2019 Aug 8;20(9):73. doi: 10.1007/s11864-019-0672-z. Review.


Sex and regional differences in myocardial plasticity in aortic stenosis are revealed by 3D model machine learning.

Bhuva AN, Treibel TA, De Marvao A, Biffi C, Dawes TJW, Doumou G, Bai W, Patel K, Boubertakh R, Rueckert D, O'Regan DP, Hughes AD, Moon JC, Manisty CH.

Eur Heart J Cardiovasc Imaging. 2020 Apr 1;21(4):417-427. doi: 10.1093/ehjci/jez166.


Cardiac Rhythm Device Identification Using Neural Networks.

Howard JP, Fisher L, Shun-Shin MJ, Keene D, Arnold AD, Ahmad Y, Cook CM, Moon JC, Manisty CH, Whinnett ZI, Cole GD, Rueckert D, Francis DP.

JACC Clin Electrophysiol. 2019 May;5(5):576-586. doi: 10.1016/j.jacep.2019.02.003. Epub 2019 Mar 27.


MRI for patients with cardiac implantable electronic devices: simplifying complexity with a 'one-stop' service model.

Bhuva AN, Feuchter P, Hawkins A, Cash L, Boubertakh R, Evanson J, Schilling R, Lowe M, Moon JC, Manisty CH.

BMJ Qual Saf. 2019 Oct;28(10):853-858. doi: 10.1136/bmjqs-2018-009079. Epub 2019 Feb 13.


Clinical impact of cardiovascular magnetic resonance with optimized myocardial scar detection in patients with cardiac implantable devices.

Bhuva AN, Kellman P, Graham A, Ramlall M, Boubertakh R, Feuchter P, Hawkins A, Lowe M, Lambiase PD, Sekhri N, Schilling RJ, Moon JC, Manisty CH.

Int J Cardiol. 2019 Mar 15;279:72-78. doi: 10.1016/j.ijcard.2019.01.005. Epub 2019 Jan 4.


Resonance as the Mechanism of Daytime Periodic Breathing in Patients with Heart Failure.

Sands SA, Mebrate Y, Edwards BA, Nemati S, Manisty CH, Desai AS, Wellman A, Willson K, Francis DP, Butler JP, Malhotra A.

Am J Respir Crit Care Med. 2017 Jan 15;195(2):237-246. doi: 10.1164/rccm.201604-0761OC.


Response to Letters Regarding Article, "Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis".

Fontana M, Pica S, Reant P, Abdel-Gadir A, Treibel TA, Banypersad SM, Maestrini V, Barcella W, Rosmini S, Bulluck H, Sayed RH, Patel K, Mamhood S, Bucciarelli-Ducci C, Whelan CJ, Herrey AS, Lachmann HJ, Wechalekar AD, Manisty CH, Schelbert EB, Kellman P, Gillmore JD, Hawkins PN, Moon JC.

Circulation. 2016 Mar 22;133(12):e450-1. doi: 10.1161/CIRCULATIONAHA.116.021162. No abstract available.


Safe use of MRI in people with cardiac implantable electronic devices.

Lowe MD, Plummer CJ, Manisty CH, Linker NJ; British Heart Rhythm Society.

Heart. 2015 Dec;101(24):1950-3. doi: 10.1136/heartjnl-2015-308495. Epub 2015 Sep 29. Review.


Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis.

Fontana M, Pica S, Reant P, Abdel-Gadir A, Treibel TA, Banypersad SM, Maestrini V, Barcella W, Rosmini S, Bulluck H, Sayed RH, Patel K, Mamhood S, Bucciarelli-Ducci C, Whelan CJ, Herrey AS, Lachmann HJ, Wechalekar AD, Manisty CH, Schelbert EB, Kellman P, Gillmore JD, Hawkins PN, Moon JC.

Circulation. 2015 Oct 20;132(16):1570-9. doi: 10.1161/CIRCULATIONAHA.115.016567. Epub 2015 Sep 11.


Automated speckle tracking algorithm to aid on-axis imaging in echocardiography.

Dhutia NM, Cole GD, Zolgharni M, Manisty CH, Willson K, Parker KH, Hughes AD, Francis DP.

J Med Imaging (Bellingham). 2014 Oct;1(3):037001. doi: 10.1117/1.JMI.1.3.037001. Epub 2014 Nov 25.


Evidence that conflict regarding size of haemodynamic response to interventricular delay optimization of cardiac resynchronization therapy may arise from differences in how atrioventricular delay is kept constant.

Sohaib SM, Kyriacou A, Jones S, Manisty CH, Mayet J, Kanagaratnam P, Peters NS, Hughes AD, Whinnett ZI, Francis DP.

Europace. 2015 Dec;17(12):1823-33. doi: 10.1093/europace/euu374. Epub 2015 Apr 7.


Effect of study design on the reported effect of cardiac resynchronization therapy (CRT) on quantitative physiological measures: stratified meta-analysis in narrow-QRS heart failure and implications for planning future studies.

Jabbour RJ, Shun-Shin MJ, Finegold JA, Afzal Sohaib SM, Cook C, Nijjer SS, Whinnett ZI, Manisty CH, Brugada J, Francis DP.

J Am Heart Assoc. 2015 Jan 6;4(1):e000896. doi: 10.1161/JAHA.114.000896. Review.


T1 mapping: non-invasive evaluation of myocardial tissue composition by cardiovascular magnetic resonance.

Bhuva AN, Treibel TA, Fontana M, Herrey AS, Manisty CH, Moon JC.

Expert Rev Cardiovasc Ther. 2014 Dec;12(12):1455-64. doi: 10.1586/14779072.2014.986098. Review.


Novel cardiac pacemaker-based human model of periodic breathing to develop real-time, pre-emptive technology for carbon dioxide stabilisation.

Baruah R, Giannoni A, Willson K, Manisty CH, Mebrate Y, Kyriacou A, Yadav H, Unsworth B, Sutton R, Mayet J, Hughes AD, Francis DP.

Open Heart. 2014 Aug 12;1(1):e000055. doi: 10.1136/openhrt-2014-000055. eCollection 2014.


Patient-accessible tool for shared decision making in cardiovascular primary prevention: balancing longevity benefits against medication disutility.

Fontana M, Asaria P, Moraldo M, Finegold J, Hassanally K, Manisty CH, Francis DP.

Circulation. 2014 Jun 17;129(24):2539-2546. doi: 10.1161/CIRCULATIONAHA.113.007595. Epub 2014 Apr 17.


Guidance for accurate and consistent tissue Doppler velocity measurement: comparison of echocardiographic methods using a simple vendor-independent method for local validation.

Dhutia NM, Zolgharni M, Willson K, Cole G, Nowbar AN, Dawson D, Zielke S, Whelan C, Newton J, Mayet J, Manisty CH, Francis DP.

Eur Heart J Cardiovasc Imaging. 2014 Jul;15(7):817-27. doi: 10.1093/ehjci/jeu040. Epub 2014 Apr 2.


What proportion of symptomatic side effects in patients taking statins are genuinely caused by the drug? Systematic review of randomized placebo-controlled trials to aid individual patient choice.

Finegold JA, Manisty CH, Goldacre B, Barron AJ, Francis DP.

Eur J Prev Cardiol. 2014 Apr;21(4):464-74. doi: 10.1177/2047487314525531. Epub 2014 Mar 12. Review.


Definitions of outcome, response and effect in imaging research to avoid confusion.

Bouri S, Whinnett ZI, Cole GD, Manisty CH, Cleland JG, Francis DP.

JACC Cardiovasc Imaging. 2014 Jan;7(1):104-6. doi: 10.1016/j.jcmg.2013.11.001. No abstract available.


Meta-analysis of symptomatic response attributable to the pacing component of cardiac resynchronization therapy.

Sohaib SM, Chen Z, Whinnett ZI, Bouri S, Dickstein K, Linde C, Hayes DL, Manisty CH, Francis DP.

Eur J Heart Fail. 2013 Dec;15(12):1419-28. doi: 10.1093/eurjhf/hft139.


Applicability of the iterative technique for cardiac resynchronization therapy optimization: full-disclosure, 50-sequential-patient dataset of transmitral Doppler traces, with implications for future research design and guidelines.

Jones S, Shun-Shin MJ, Cole GD, Sau A, March K, Williams S, Kyriacou A, Hughes AD, Mayet J, Frenneaux M, Manisty CH, Whinnett ZI, Francis DP.

Europace. 2014 Apr;16(4):541-50. doi: 10.1093/europace/eut257. Epub 2013 Sep 25. Review.


First-in-man safety evaluation of renal denervation for chronic systolic heart failure: primary outcome from REACH-Pilot study.

Davies JE, Manisty CH, Petraco R, Barron AJ, Unsworth B, Mayet J, Hamady M, Hughes AD, Sever PS, Sobotka PA, Francis DP.

Int J Cardiol. 2013 Jan 20;162(3):189-92. doi: 10.1016/j.ijcard.2012.09.019. Epub 2012 Sep 29.


Attenuation of wave reflection by wave entrapment creates a "horizon effect" in the human aorta.

Davies JE, Alastruey J, Francis DP, Hadjiloizou N, Whinnett ZI, Manisty CH, Aguado-Sierra J, Willson K, Foale RA, Malik IS, Hughes AD, Parker KH, Mayet J.

Hypertension. 2012 Sep;60(3):778-85. doi: 10.1161/HYPERTENSIONAHA.111.180604. Epub 2012 Jul 16.


Choosing between velocity-time-integral ratio and peak velocity ratio for calculation of the dimensionless index (or aortic valve area) in serial follow-up of aortic stenosis.

Finegold JA, Manisty CH, Cecaro F, Sutaria N, Mayet J, Francis DP.

Int J Cardiol. 2013 Aug 20;167(4):1524-31. doi: 10.1016/j.ijcard.2012.04.105. Epub 2012 May 8.


When is a "free" registrar in clinic not free?

Lota AS, Manisty CH, Sutton R, Francis DP.

BMJ. 2011 Dec 20;343:d7869. doi: 10.1136/bmj.d7869.


The acute effects of changes to AV delay on BP and stroke volume: potential implications for design of pacemaker optimization protocols.

Manisty CH, Al-Hussaini A, Unsworth B, Baruah R, Pabari PA, Mayet J, Hughes AD, Whinnett ZI, Francis DP.

Circ Arrhythm Electrophysiol. 2012 Feb;5(1):122-30. doi: 10.1161/CIRCEP.111.964205. Epub 2011 Nov 17.


Real-time dynamic carbon dioxide administration: a novel treatment strategy for stabilization of periodic breathing with potential application to central sleep apnea.

Giannoni A, Baruah R, Willson K, Mebrate Y, Mayet J, Emdin M, Hughes AD, Manisty CH, Francis DP.

J Am Coll Cardiol. 2010 Nov 23;56(22):1832-7. doi: 10.1016/j.jacc.2010.05.053.


Maximizing efficiency of alternation algorithms for hemodynamic optimization of the AV delay of cardiac resynchronization therapy.

Whinnett ZI, Nott G, Davies JE, Willson K, Manisty CH, Kanagaratnam P, Peters NS, Davies DW, Hughes AD, Mayet J, Francis DP.

Pacing Clin Electrophysiol. 2011 Feb;34(2):217-25. doi: 10.1111/j.1540-8159.2010.02933.x. Epub 2010 Oct 4.


The arterial reservoir pressure increases with aging and is the major determinant of the aortic augmentation index.

Davies JE, Baksi J, Francis DP, Hadjiloizou N, Whinnett ZI, Manisty CH, Aguado-Sierra J, Foale RA, Malik IS, Tyberg JV, Parker KH, Mayet J, Hughes AD.

Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H580-6. doi: 10.1152/ajpheart.00875.2009. Epub 2009 Dec 11.


Novel use of cardiac pacemakers in heart failure to dynamically manipulate the respiratory system through algorithmic changes in cardiac output.

Baruah R, Manisty CH, Giannoni A, Willson K, Mebrate Y, Baksi AJ, Unsworth B, Hadjiloizou N, Sutton R, Mayet J, Francis DP.

Circ Heart Fail. 2009 May;2(3):166-74. doi: 10.1161/CIRCHEARTFAILURE.108.806588. Epub 2009 Mar 23.


Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian Cardiac Outcome Trial substudy.

Manisty CH, Zambanini A, Parker KH, Davies JE, Francis DP, Mayet J, McG Thom SA, Hughes AD; Anglo-Scandinavian Cardiac Outcome Trial Investigators.

Hypertension. 2009 Oct;54(4):724-30. doi: 10.1161/HYPERTENSIONAHA.108.125740. Epub 2009 Aug 24.


Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes.

Mebrate Y, Willson K, Manisty CH, Baruah R, Mayet J, Hughes AD, Parker KH, Francis DP.

J Appl Physiol (1985). 2009 Sep;107(3):696-706. doi: 10.1152/japplphysiol.90308.2008. Epub 2009 Jul 23.


Quantifying the paradoxical effect of higher systolic blood pressure on mortality in chronic heart failure.

Raphael CE, Whinnett ZI, Davies JE, Fontana M, Ferenczi EA, Manisty CH, Mayet J, Francis DP.

Heart. 2009 Jan;95(1):56-62. doi: 10.1136/hrt.2007.134973. Epub 2008 Jul 24. Review.


Induction of oscillatory ventilation pattern using dynamic modulation of heart rate through a pacemaker.

Manisty CH, Willson K, Davies JE, Whinnett ZI, Baruah R, Mebrate Y, Kanagaratnam P, Peters NS, Hughes AD, Mayet J, Francis DP.

Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R219-27. doi: 10.1152/ajpregu.00064.2008. Epub 2008 May 7.


Ejection fraction: a measure of desperation?

Manisty CH, Francis DP.

Heart. 2008 Apr;94(4):400-1. doi: 10.1136/hrt.2007.118976. No abstract available.


The atrioventricular delay of cardiac resynchronization can be optimized hemodynamically during exercise and predicted from resting measurements.

Whinnett ZI, Briscoe C, Davies JE, Willson K, Manisty CH, Davies DW, Peters NS, Kanagaratnam P, Hughes AD, Mayet J, Francis DP.

Heart Rhythm. 2008 Mar;5(3):378-86. doi: 10.1016/j.hrthm.2007.11.019. Epub 2007 Dec 4.


Efficiency, reproducibility and agreement of five different hemodynamic measures for optimization of cardiac resynchronization therapy.

Whinnett ZI, Davies JE, Nott G, Willson K, Manisty CH, Peters NS, Kanagaratnam P, Davies DW, Hughes AD, Mayet J, Francis DP.

Int J Cardiol. 2008 Sep 26;129(2):216-26. Epub 2007 Sep 18.


Increased mechanoreceptor/metaboreceptor stimulation explains the exaggerated exercise pressor reflex seen in heart failure.

Manisty CH, Francis DP.

J Appl Physiol (1985). 2007 Jan;102(1):501; author reply 504-5. doi: 10.1152/japplphysiol.01247.2006. No abstract available.


Development of respiratory control instability in heart failure: a novel approach to dissect the pathophysiological mechanisms.

Manisty CH, Willson K, Wensel R, Whinnett ZI, Davies JE, Oldfield WL, Mayet J, Francis DP.

J Physiol. 2006 Nov 15;577(Pt 1):387-401. Epub 2006 Sep 7.


Evidence of a dominant backward-propagating "suction" wave responsible for diastolic coronary filling in humans, attenuated in left ventricular hypertrophy.

Davies JE, Whinnett ZI, Francis DP, Manisty CH, Aguado-Sierra J, Willson K, Foale RA, Malik IS, Hughes AD, Parker KH, Mayet J.

Circulation. 2006 Apr 11;113(14):1768-78. Epub 2006 Apr 3.


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