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Items: 11

1.

2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition.

Schwartz PS, Manion MK, Emerson CB, Fry JS, Schulz CM, Sweet IR, Hockenbery DM.

Mol Cancer Ther. 2007 Jul;6(7):2073-80.

2.

Small-molecule inhibitors of Bcl-2.

Manion MK, Fry J, Schwartz PS, Hockenbery DM.

Curr Opin Investig Drugs. 2006 Dec;7(12):1077-84. Review.

PMID:
17209525
3.

BCL-XL dimerization by three-dimensional domain swapping.

O'Neill JW, Manion MK, Maguire B, Hockenbery DM.

J Mol Biol. 2006 Feb 17;356(2):367-81. Epub 2005 Dec 1.

PMID:
16368107
4.

A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve system.

Erxleben HA, Manion MK, Hockenbery DM, Scampavia L, Ruzicka J.

Analyst. 2004 Mar;129(3):205-12. Epub 2004 Feb 2.

PMID:
14978521
5.

Bcl-XL mutations suppress cellular sensitivity to antimycin A.

Manion MK, O'Neill JW, Giedt CD, Kim KM, Zhang KY, Hockenbery DM.

J Biol Chem. 2004 Jan 16;279(3):2159-65. Epub 2003 Oct 8.

6.

Targeting BCL-2-related proteins in cancer therapy.

Manion MK, Hockenbery DM.

Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S105-14. Review.

PMID:
14508087
7.

Mitochondria and apoptosis: new therapeutic targets.

Hockenbery DM, Giedt CD, O'Neill JW, Manion MK, Banker DE.

Adv Cancer Res. 2002;85:203-42. Review. No abstract available.

PMID:
12374287
8.

Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma.

Ten Broeke R, Folkerts G, Leusink-Muis T, Van der Linde HJ, Villain M, Manion MK, De Clerck F, Blalock JE, Nijkamp FP.

FASEB J. 2001 Aug;15(10):1831-3. No abstract available.

PMID:
11481245
9.

Cellular uptake and in situ binding of a peptide agonist for calmodulin.

Manion MK, Villain M, Pan ZG, McDonald JM, Blalock JE.

Biochem Biophys Res Commun. 2000 Oct 22;277(2):462-9.

PMID:
11032745
10.

A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents Ca(2+)-mediated apoptosis.

Manion MK, Su Z, Villain M, Blalock JE.

FASEB J. 2000 Jul;14(10):1297-306.

PMID:
10877822
11.

De novo design of peptides targeted to the EF hands of calmodulin.

Villain M, Jackson PL, Manion MK, Dong WJ, Su Z, Fassina G, Johnson TM, Sakai TT, Krishna NR, Blalock JE.

J Biol Chem. 2000 Jan 28;275(4):2676-85.

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