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Items: 14


Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers.

Pearce OMT, Delaine-Smith RM, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, Cutillas PR, Lockley M, Bessant C, Knight MM, Balkwill FR.

Cancer Discov. 2018 Mar;8(3):304-319. doi: 10.1158/2159-8290.CD-17-0284. Epub 2017 Dec 1.


A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

Berlato C, Khan MN, Schioppa T, Thompson R, Maniati E, Montfort A, Jangani M, Canosa M, Kulbe H, Hagemann UB, Duncan AR, Fletcher L, Wilkinson RW, Powles T, Quezada SA, Balkwill FR.

J Clin Invest. 2017 Mar 1;127(3):801-813. doi: 10.1172/JCI82976. Epub 2017 Jan 30.


A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases.

Montfort A, Pearce O, Maniati E, Vincent BG, Bixby L, Böhm S, Dowe T, Wilkes EH, Chakravarty P, Thompson R, Topping J, Cutillas PR, Lockley M, Serody JS, Capasso M, Balkwill FR.

Clin Cancer Res. 2017 Jan 1;23(1):250-262. doi: 10.1158/1078-0432.CCR-16-0081. Epub 2016 Jun 27.


Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

Dawkins JB, Wang J, Maniati E, Heward JA, Koniali L, Kocher HM, Martin SA, Chelala C, Balkwill FR, Fitzgibbon J, Grose RP.

Cancer Res. 2016 Aug 15;76(16):4861-71. doi: 10.1158/0008-5472.CAN-16-0481. Epub 2016 Jun 8.


Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity.

Serrels A, Lund T, Serrels B, Byron A, McPherson RC, von Kriegsheim A, Gómez-Cuadrado L, Canel M, Muir M, Ring JE, Maniati E, Sims AH, Pachter JA, Brunton VG, Gilbert N, Anderton SM, Nibbs RJ, Frame MC.

Cell. 2015 Sep 24;163(1):160-73. doi: 10.1016/j.cell.2015.09.001.


A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer.

Chard LS, Maniati E, Wang P, Zhang Z, Gao D, Wang J, Cao F, Ahmed J, El Khouri M, Hughes J, Wang S, Li X, Denes B, Fodor I, Hagemann T, Lemoine NR, Wang Y.

Clin Cancer Res. 2015 Jan 15;21(2):405-16. doi: 10.1158/1078-0432.CCR-14-0464. Epub 2014 Nov 21.


Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis.

Batista S, Maniati E, Reynolds LE, Tavora B, Lees DM, Fernandez I, Elia G, Casanovas O, Lo Celso C, Hagemann T, Hodivala-Dilke K.

Nat Commun. 2014 Oct 1;5:5054. doi: 10.1038/ncomms6054.


IL-17 mediates resistance to anti-VEGF therapy.

Maniati E, Hagemann T.

Nat Med. 2013 Sep;19(9):1092-4. doi: 10.1038/nm.3333.


Macrophage scavenger receptor a promotes tumor progression in murine models of ovarian and pancreatic cancer.

Neyen C, Plüddemann A, Mukhopadhyay S, Maniati E, Bossard M, Gordon S, Hagemann T.

J Immunol. 2013 Apr 1;190(7):3798-805. doi: 10.4049/jimmunol.1203194. Epub 2013 Feb 27.


Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.

Maniati E, Bossard M, Cook N, Candido JB, Emami-Shahri N, Nedospasov SA, Balkwill FR, Tuveson DA, Hagemann T.

J Clin Invest. 2011 Dec;121(12):4685-99. doi: 10.1172/JCI45797. Epub 2011 Nov 7.


Up for Mischief? IL-17/Th17 in the tumour microenvironment.

Maniati E, Soper R, Hagemann T.

Oncogene. 2010 Oct 21;29(42):5653-62. doi: 10.1038/onc.2010.367. Epub 2010 Aug 23. Review.


A defect in Marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells.

Rogers NJ, Lees MJ, Gabriel L, Maniati E, Rose SJ, Potter PK, Morley BJ.

J Immunol. 2009 Feb 15;182(4):1982-90. doi: 10.4049/jimmunol.0801320.


Control of apoptosis in autoimmunity.

Maniati E, Potter P, Rogers NJ, Morley BJ.

J Pathol. 2008 Jan;214(2):190-8. Review.


Fulminant meningococcemia. Heparin therapy and survival rate.

Manios SG, Kanakoudi F, Maniati E.

Scand J Infect Dis. 1971;3(2):127-33. No abstract available.


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