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Clinical spectrum, susceptibility profile, treatment and outcome of culture-confirmed brucellosis from South India.

Mani SSR, Gunasekaran K, Iyyadurai R, Prakash JAJ, Veeraraghavan B, Mishra AK, Sabnis K, Victor PJ, Martin S, Chandiraseharan VK, Hansdak SG, Varghese GM.

Indian J Med Microbiol. 2018 Apr-Jun;36(2):289-292. doi: 10.4103/ijmm.IJMM_18_236.


A Novel Shigella Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge.

Ndungo E, Randall A, Hazen TH, Kania DA, Trappl-Kimmons K, Liang X, Barry EM, Kotloff KL, Chakraborty S, Mani S, Rasko DA, Pasetti MF.

mSphere. 2018 Aug 1;3(4). pii: e00260-18. doi: 10.1128/mSphere.00260-18.


Zika virus E protein alters the properties of human fetal neural stem cells by modulating microRNA circuitry.

Bhagat R, Prajapati B, Narwal S, Agnihotri N, Adlakha YK, Sen J, Mani S, Seth P.

Cell Death Differ. 2018 Jul 26. doi: 10.1038/s41418-018-0163-y. [Epub ahead of print]


Management and Outcome in Patients with Advanced Juvenile Nasopharyngeal Angiofibroma.

Rupa V, Mani SE, Backianathan S, Rajshekhar V.

J Neurol Surg B Skull Base. 2018 Aug;79(4):353-360. doi: 10.1055/s-0037-1608658. Epub 2017 Nov 27.


Telmisartan Ameliorates Astroglial and Dopaminergic Functions in a Mouse Model of Chronic Parkinsonism.

Sekar S, Mani S, Rajamani B, Manivasagam T, Thenmozhi AJ, Bhat A, Ray B, Essa MM, Guillemin GJ, Chidambaram SB.

Neurotox Res. 2018 Jul 13. doi: 10.1007/s12640-018-9921-3. [Epub ahead of print]


Hybrid epithelial/mesenchymal phenotype(s): The 'fittest' for metastasis?

Jolly MK, Mani SA, Levine H.

Biochim Biophys Acta. 2018 Jul 8. pii: S0304-419X(18)30064-7. doi: 10.1016/j.bbcan.2018.07.001. [Epub ahead of print] Review.


EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers.

Soundararajan R, Paranjape AN, Maity S, Aparicio A, Mani SA.

Biochim Biophys Acta. 2018 Jul 5. pii: S0304-419X(18)30089-1. doi: 10.1016/j.bbcan.2018.06.006. [Epub ahead of print] Review.


Development, Interlaboratory Evaluations, and Application of a Simple, High-Throughput Shigella Serum Bactericidal Assay.

Nahm MH, Yu J, Weerts HP, Wenzel H, Tamilselvi CS, Chandrasekaran L, Pasetti MF, Mani S, Kaminski RW.

mSphere. 2018 Jun 13;3(3). pii: e00146-18. doi: 10.1128/mSphere.00146-18. Print 2018 Jun 27.


Human experimental challenge with enterotoxigenic Escherichia coli elicits immune responses to canonical and novel antigens relevant to vaccine development.

Chakraborty S, Randall A, Vickers TJ, Molina D, Harro CD, DeNearing B, Brubaker J, Sack DA, Bourgeois AL, Felgner PL, Liang X, Mani S, Wenzel H, Townsend RR, Gilmore PE, Darsley MJ, Rasko DA, Fleckenstein JM.

J Infect Dis. 2018 May 24. doi: 10.1093/infdis/jiy312. [Epub ahead of print]


Role of Noninvasive Imaging of Cerebral Arterial System in Ischemic Stroke: Comparison of Transcranial Color-coded Doppler Sonography with Magnetic Resonance Angiography.

Simon B, Mani SE, Keshava SN, Alexander M, Aaron S.

J Clin Imaging Sci. 2018 Apr 20;8:19. doi: 10.4103/jcis.JCIS_13_18. eCollection 2018.


Comparison of telemedicine with in-person care for follow-up after elective neurosurgery: results of a cost-effectiveness analysis of 1200 patients using patient-perceived utility scores.

Thakar S, Rajagopal N, Mani S, Shyam M, Aryan S, Rao AS, Srinivasa R, Mohan D, Hegde AS.

Neurosurg Focus. 2018 May;44(5):E17. doi: 10.3171/2018.2.FOCUS17543.


Mitochondrial Donation: A Boon or Curse for the Treatment of Incurable Mitochondrial Diseases.

Saxena N, Taneja N, Shome P, Mani S.

J Hum Reprod Sci. 2018 Jan-Mar;11(1):3-9. doi: 10.4103/jhrs.JHRS_54_17. Review.


HDAC inhibition helps post-MI healing by modulating macrophage polarization.

Kimbrough D, Wang SH, Wright LH, Mani SK, Kasiganesan H, LaRue AC, Cheng Q, Nadig SN, Atkinson C, Menick DR.

J Mol Cell Cardiol. 2018 Jun;119:51-63. doi: 10.1016/j.yjmcc.2018.04.011. Epub 2018 Apr 19.



Vanjare HA, Mani S.

AJNR Am J Neuroradiol. 2018 Jul;39(7):E85. doi: 10.3174/ajnr.A5658. Epub 2018 Apr 19. No abstract available.


Centrosome Inheritance Does Not Regulate Cell Fate in Granule Neuron Progenitors of the Developing Cerebellum.

Chatterjee A, Chinnappa K, Ramanan N, Mani S.

Cerebellum. 2018 Apr 16. doi: 10.1007/s12311-018-0935-4. [Epub ahead of print]


The Non-Coding RNA Journal Club: Highlights on Recent Papers-5.

Achour C, Bogard B, Hubé F, Mani SA, Santulli G, Taube JH.

Noncoding RNA. 2017 Jun 14;3(2). pii: E21. doi: 10.3390/ncrna3020021.


Hybrid polycaprolactone/polyethylene oxide scaffolds with tunable fiber surface morphology, improved hydrophilicity and biodegradability for bone tissue engineering applications.

Remya KR, Chandran S, Mani S, John A, Ramesh P.

J Biomater Sci Polym Ed. 2018 Aug;29(12):1444-1462. doi: 10.1080/09205063.2018.1465664. Epub 2018 May 1.


Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor.

Stepankova M, Bartonkova I, Jiskrova E, Vrzal R, Mani S, Kortagere S, Dvorak Z.

Mol Pharmacol. 2018 Jun;93(6):631-644. doi: 10.1124/mol.118.112151. Epub 2018 Apr 6.


Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin.

Zhou P, Fan H, Lan T, Yang XL, Shi WF, Zhang W, Zhu Y, Zhang YW, Xie QM, Mani S, Zheng XS, Li B, Li JM, Guo H, Pei GQ, An XP, Chen JW, Zhou L, Mai KJ, Wu ZX, Li D, Anderson DE, Zhang LB, Li SY, Mi ZQ, He TT, Cong F, Guo PJ, Huang R, Luo Y, Liu XL, Chen J, Huang Y, Sun Q, Zhang XL, Wang YY, Xing SZ, Chen YS, Sun Y, Li J, Daszak P, Wang LF, Shi ZL, Tong YG, Ma JY.

Nature. 2018 Apr;556(7700):255-258. doi: 10.1038/s41586-018-0010-9. Epub 2018 Apr 4.


Teaching NeuroImages: Autosomal recessive spastic ataxia of Charlevoix-Saguenay: Typical MRI findings.

Biswas A, Varman M, Yoganathan S, Subhash PK, Mani S.

Neurology. 2018 Apr 3;90(14):e1271-e1272. doi: 10.1212/WNL.0000000000005252. No abstract available.


Function of Tumor Suppressors in Resistance to Antiandrogen Therapy and Luminal Epithelial Plasticity of Aggressive Variant Neuroendocrine Prostate Cancers.

Soundararajan R, Aparicio AM, Logothetis CJ, Mani SA, Maity SN.

Front Oncol. 2018 Mar 15;8:69. doi: 10.3389/fonc.2018.00069. eCollection 2018. Review.


Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):377. doi: 10.1038/nrd.2018.52. Epub 2018 Mar 23.


Hydrothermal Synthesis of Cr2Se3 Hexagons for Sensitive and Low-level Detection of 4-Nitrophenol in Water.

Ramaraj S, Mani S, Chen SM, Palanisamy S, Velusamy V, Hall JM, Chen TW, Tseng TW.

Sci Rep. 2018 Mar 19;8(1):4839. doi: 10.1038/s41598-018-23243-3.


Degradation and decolourization potential of an ligninolytic enzyme producing Aeromonas hydrophila for crystal violet dye and its phytotoxicity evaluation.

Bharagava RN, Mani S, Mulla SI, Saratale GD.

Ecotoxicol Environ Saf. 2018 Jul 30;156:166-175. doi: 10.1016/j.ecoenv.2018.03.012. Epub 2018 Mar 20.


Risk Factors for Addiction Potential among College Students.

Ranjbaran M, Mohammadshahi F, Mani S, Karimy M.

Int J Prev Med. 2018 Feb 8;9:17. doi: 10.4103/ijpvm.IJPVM_403_16. eCollection 2018.


GnRH-(1-5) Inhibits TGF-β Signaling to Regulate the Migration of Immortalized Gonadotropin-Releasing Hormone Neurons.

Larco DO, Bauman BM, Cho-Clark M, Mani SK, Wu TJ.

Front Endocrinol (Lausanne). 2018 Feb 20;9:45. doi: 10.3389/fendo.2018.00045. eCollection 2018.


Hepatitis B Virus-Associated Hepatocellular Carcinoma and Hepatic Cancer Stem Cells.

Mani SKK, Andrisani O.

Genes (Basel). 2018 Mar 2;9(3). pii: E137. doi: 10.3390/genes9030137. Review.


Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Review. Erratum in: Nat Rev Drug Discov. 2018 Mar 23;:.


Brain Imaging in Cases with Positive Serology for Dengue with Neurologic Symptoms: A Clinicoradiologic Correlation.

Vanjare HA, Mannam P, Mishra AK, Karuppusami R, Carey RAB, Abraham AM, Rose W, Iyyadurai R, Mani S.

AJNR Am J Neuroradiol. 2018 Apr;39(4):699-703. doi: 10.3174/ajnr.A5544. Epub 2018 Feb 8.


Naringenin Decreases α-Synuclein Expression and Neuroinflammation in MPTP-Induced Parkinson's Disease Model in Mice.

Mani S, Sekar S, Barathidasan R, Manivasagam T, Thenmozhi AJ, Sevanan M, Chidambaram SB, Essa MM, Guillemin GJ, Sakharkar MK.

Neurotox Res. 2018 Apr;33(3):656-670. doi: 10.1007/s12640-018-9869-3. Epub 2018 Feb 9.


Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis.

Huang K, Mukherjee S, DesMarais V, Albanese JM, Rafti E, Draghi Ii A, Maher LA, Khanna KM, Mani S, Matson AP.

Pediatr Res. 2018 May;83(5):1031-1040. doi: 10.1038/pr.2018.14. Epub 2018 Feb 21.


STIL balancing primary microcephaly and cancer.

Patwardhan D, Mani S, Passemard S, Gressens P, El Ghouzzi V.

Cell Death Dis. 2018 Jan 19;9(2):65. doi: 10.1038/s41419-017-0101-9. Review.


Dental age estimation employing CBCT scans enhanced with Mimics software: Comparison of two different approaches using pulp/tooth volumetric analysis.

Asif MK, Nambiar P, Mani SA, Ibrahim NB, Khan IM, Sukumaran P.

J Forensic Leg Med. 2018 Feb;54:53-61. doi: 10.1016/j.jflm.2017.12.010. Epub 2018 Jan 4.


A randomized controlled trial to determine the role of intraoperative lumbar cerebrospinal fluid drainage in patients undergoing endoscopic transsphenoidal surgery for pituitary adenomas.

Jonathan GE, Sarkar S, Singh G, Mani S, Thomas R, Chacko AG.

Neurol India. 2018 Jan-Feb;66(1):133-138. doi: 10.4103/0028-3886.222823.


Thraatchathi Chooranam, protects cardiomyocytes against oxidative stress.

Ganapathy R, Mani S, Hanumanth Rao BR, Tunku K, Ray B, Bhat A, Chidambaram SB.

Front Biosci (Elite Ed). 2018 Mar 1;10:437-448.


Improved thermal stability of cellulose nanofibrils using low-concentration alkaline pretreatment.

Lee H, Sundaram J, Zhu L, Zhao Y, Mani S.

Carbohydr Polym. 2018 Feb 1;181:506-513. doi: 10.1016/j.carbpol.2017.08.119. Epub 2017 Sep 7.


Synthesis and application of bismuth ferrite nanosheets supported functionalized carbon nanofiber for enhanced electrochemical detection of toxic organic compound in water samples.

Ramaraj S, Mani S, Chen SM, Kokulnathan T, Lou BS, Ali MA, Hatamleh AA, Al-Hemaid FMA.

J Colloid Interface Sci. 2018 Mar 15;514:59-69. doi: 10.1016/j.jcis.2017.12.016. Epub 2017 Dec 6.


Effective models for antimetastatic therapies.

Tian L, Zhang XHF, Mani SA.

Oncotarget. 2017 Jun 6;8(55):93295-93296. doi: 10.18632/oncotarget.18379. eCollection 2017 Nov 7. No abstract available.


Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice.

Luo X, Yu Z, Deng C, Zhang J, Ren G, Sun A, Mani S, Wang Z, Dou W.

Sci Rep. 2017 Nov 27;7(1):16374. doi: 10.1038/s41598-017-12562-6.


Microbiota and Breast Cancer.

Mani S.

Prog Mol Biol Transl Sci. 2017;151:217-229. doi: 10.1016/bs.pmbts.2017.07.004. Epub 2017 Aug 31. Review.


A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers.

Bollong MJ, Pietilä M, Pearson AD, Sarkar TR, Ahmad I, Soundararajan R, Lyssiotis CA, Mani SA, Schultz PG, Lairson LL.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9903-E9912. doi: 10.1073/pnas.1716009114. Epub 2017 Oct 30.


The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition.

Taube JH, Sphyris N, Johnson KS, Reisenauer KN, Nesbit TA, Joseph R, Vijay GV, Sarkar TR, Bhangre NA, Song JJ, Chang JT, Lee MG, Soundararajan R, Mani SA.

Oncotarget. 2017 Jul 10;8(39):65548-65565. doi: 10.18632/oncotarget.19214. eCollection 2017 Sep 12.


Formalizing drug indications on the road to therapeutic intent.

Nelson SJ, Oprea TI, Ursu O, Bologa CG, Zaveri A, Holmes J, Yang JJ, Mathias SL, Mani S, Tuttle MS, Dumontier M.

J Am Med Inform Assoc. 2017 Nov 1;24(6):1169-1172. doi: 10.1093/jamia/ocx064.


Vaccines against Shigella and enterotoxigenic Escherichia coli: A summary of the 2016 VASE Conference.

Walker RI, Wierzba TF, Mani S, Bourgeois AL.

Vaccine. 2017 Dec 14;35(49 Pt A):6775-6782. doi: 10.1016/j.vaccine.2017.09.045. Epub 2017 Oct 4.


Intergenerational Transmission of Poverty and Inequality: Parental Resources and Schooling Attainment and Children's Human Capital in Ethiopia, India, Peru, and Vietnam.

Behrman JR, Schott W, Mani S, Crookston BT, Dearden K, Duc LT, Fernald LCH, Stein AD; Young Lives Determinants and Consequences of Child Growth Project Team.

Econ Dev Cult Change. 2017 Jul;65(4):657-697. doi: 10.1086/691971. Epub 2017 Apr 10.


Spectrum of Visual Impairment in Cerebral Venous Thrombosis: Importance of Tailoring Therapies Based on Pathophysiology.

Aaron S, Arthur A, Prabakhar AT, Mannam P, Shyamkumar NK, Mani S, Mathew V, Peter J, Sivadasan A, Alexander A, Karthik M, Benjamin RN, Alexander M.

Ann Indian Acad Neurol. 2017 Jul-Sep;20(3):294-301. doi: 10.4103/aian.AIAN_11_17.


Indole microbial metabolites: expanding and translating target(s).

Mani S.

Oncotarget. 2017 Jul 22;8(32):52014-52015. doi: 10.18632/oncotarget.19443. eCollection 2017 Aug 8. No abstract available.

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