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Items: 26


Evaluation of select biocompatible markers for labelling peripheral nerves on 11.7 T MRI.

Gullotti D, Mangraviti A, Zhang J, Volpin F, Fink G, Reiss R, Ahlawat S, Olivi A, Hoke A, Tyler B, Belzberg A.

J Neurosci Methods. 2019 Mar 1;315:6-13. doi: 10.1016/j.jneumeth.2018.12.019. Epub 2019 Jan 7.


Surgical Management of Intracranial Giant Epidermoid Cysts in Adult: A Case-Based Update.

Mangraviti A, Mazzucchi E, Izzo A, Sturdà C, Albanese A, Marchese E, Olivi A, Puca A, Sturiale CL.

Asian J Neurosurg. 2018 Oct-Dec;13(4):1288-1291. doi: 10.4103/ajns.AJNS_91_18.


Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant glioma patients.

Joshi AD, Botham RC, Schlein LJ, Roth HS, Mangraviti A, Borodovsky A, Tyler B, Joslyn S, Looper JS, Podell M, Fan TM, Hergenrother PJ, Riggins GJ.

Oncotarget. 2017 Jul 7;8(46):80124-80138. doi: 10.18632/oncotarget.19085. eCollection 2017 Oct 6.


HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy.

Mangraviti A, Raghavan T, Volpin F, Skuli N, Gullotti D, Zhou J, Asnaghi L, Sankey E, Liu A, Wang Y, Lee DH, Gorelick N, Serra R, Peters M, Schriefer D, Delaspre F, Rodriguez FJ, Eberhart CG, Brem H, Olivi A, Tyler B.

Sci Rep. 2017 Nov 2;7(1):14978. doi: 10.1038/s41598-017-14990-w.


Developing Therapies for Brain Tumors: The Impact of the Johns Hopkins Hunterian Neurosurgical Research Laboratory.

Brem H, Sankey EW, Liu A, Mangraviti A, Tyler BM.

Trans Am Clin Climatol Assoc. 2017;128:55-74. Review.


Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM.

Mathios D, Kim JE, Mangraviti A, Phallen J, Park CK, Jackson CM, Garzon-Muvdi T, Kim E, Theodros D, Polanczyk M, Martin AM, Suk I, Ye X, Tyler B, Bettegowda C, Brem H, Pardoll DM, Lim M.

Sci Transl Med. 2016 Dec 21;8(370):370ra180. doi: 10.1126/scitranslmed.aag2942.


The semisitting position: analysis of the risks and surgical outcomes in a contemporary series of 425 adult patients undergoing cranial surgery.

Saladino A, Lamperti M, Mangraviti A, Legnani FG, Prada FU, Casali C, Caputi L, Borrelli P, DiMeco F.

J Neurosurg. 2017 Oct;127(4):867-876. doi: 10.3171/2016.8.JNS16719. Epub 2016 Dec 16.


Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.

Volpin F, Casaos J, Sesen J, Mangraviti A, Choi J, Gorelick N, Frikeche J, Lott T, Felder R, Scotland SJ, Eisinger-Mathason TSK, Brem H, Tyler B, Skuli N.

Oncogene. 2017 May 25;36(21):3037-3047. doi: 10.1038/onc.2016.457. Epub 2016 Dec 12.


Polylactic acid (PLA) controlled delivery carriers for biomedical applications.

Tyler B, Gullotti D, Mangraviti A, Utsuki T, Brem H.

Adv Drug Deliv Rev. 2016 Dec 15;107:163-175. doi: 10.1016/j.addr.2016.06.018. Epub 2016 Jul 15. Review.


Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas.

Kim JE, Patel MA, Mangraviti A, Kim ES, Theodros D, Velarde E, Liu A, Sankey EW, Tam A, Xu H, Mathios D, Jackson CM, Harris-Bookman S, Garzon-Muvdi T, Sheu M, Martin AM, Tyler BM, Tran PT, Ye X, Olivi A, Taube JM, Burger PC, Drake CG, Brem H, Pardoll DM, Lim M.

Clin Cancer Res. 2017 Jan 1;23(1):124-136. doi: 10.1158/1078-0432.CCR-15-1535. Epub 2016 Jun 29.


Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival.

Mangraviti A, Tzeng SY, Gullotti D, Kozielski KL, Kim JE, Seng M, Abbadi S, Schiapparelli P, Sarabia-Estrada R, Vescovi A, Brem H, Olivi A, Tyler B, Green JJ, Quinones-Hinojosa A.

Biomaterials. 2016 Sep;100:53-66. doi: 10.1016/j.biomaterials.2016.05.025. Epub 2016 May 21.


Multi-parametric MRI Assessment of Tumor Response to High-Intensity Focused Ultrasound in a Rat Glioma Model.

Zhang Y, Lee DH, Zhang K, Mangraviti A, Yang C, Heo HY, Tyler B, Partanen A, Farahani K, Bottomley P, van Zijl P, Zhou J.

Proc Int Soc Magn Reson Med Sci Meet Exhib Int Soc Magn Reson Med Sci Meet Exhib. 2015 May-Jun;2015:0036. No abstract available.


Nanobiotechnology-based delivery strategies: New frontiers in brain tumor targeted therapies.

Mangraviti A, Gullotti D, Tyler B, Brem H.

J Control Release. 2016 Oct 28;240:443-453. doi: 10.1016/j.jconrel.2016.03.031. Epub 2016 Mar 23. Review.


The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory.

Tyler BM, Liu A, Sankey EW, Mangraviti A, Barone MA, Brem H.

Acad Med. 2016 Jun;91(6):778-84. doi: 10.1097/ACM.0000000000001136.


Immune Checkpoint Modulators: An Emerging Antiglioma Armamentarium.

Kim ES, Kim JE, Patel MA, Mangraviti A, Ruzevick J, Lim M.

J Immunol Res. 2016;2016:4683607. doi: 10.1155/2016/4683607. Epub 2016 Jan 4. Review.


The effect of regadenoson-induced transient disruption of the blood-brain barrier on temozolomide delivery to normal rat brain.

Jackson S, Anders NM, Mangraviti A, Wanjiku TM, Sankey EW, Liu A, Brem H, Tyler B, Rudek MA, Grossman SA.

J Neurooncol. 2016 Feb;126(3):433-9. doi: 10.1007/s11060-015-1998-4. Epub 2015 Dec 1.


Quantitative correlational study of microbubble-enhanced ultrasound imaging and magnetic resonance imaging of glioma and early response to radiotherapy in a rat model.

Yang C, Lee DH, Mangraviti A, Su L, Zhang K, Zhang Y, Zhang B, Li W, Tyler B, Wong J, Wang KK, Velarde E, Zhou J, Ding K.

Med Phys. 2015 Aug;42(8):4762-72. doi: 10.1118/1.4926550.


Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers.

Zhang F, Mastorakos P, Mishra MK, Mangraviti A, Hwang L, Zhou J, Hanes J, Brem H, Olivi A, Tyler B, Kannan RM.

Biomaterials. 2015 Jun;52:507-16. doi: 10.1016/j.biomaterials.2015.02.053. Epub 2015 Mar 18.


Interstitial chemotherapy for malignant glioma: Future prospects in the era of multimodal therapy.

Mangraviti A, Tyler B, Brem H.

Surg Neurol Int. 2015 Feb 13;6(Suppl 1):S78-84. doi: 10.4103/2152-7806.151345. eCollection 2015.


Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo.

Mangraviti A, Tzeng SY, Kozielski KL, Wang Y, Jin Y, Gullotti D, Pedone M, Buaron N, Liu A, Wilson DR, Hansen SK, Rodriguez FJ, Gao GD, DiMeco F, Brem H, Olivi A, Tyler B, Green JJ.

ACS Nano. 2015 Feb 24;9(2):1236-49. doi: 10.1021/nn504905q. Epub 2015 Feb 10.


Fusion imaging for intra-operative ultrasound-based navigation in neurosurgery.

Prada F, Del Bene M, Mattei L, Casali C, Filippini A, Legnani F, Mangraviti A, Saladino A, Perin A, Richetta C, Vetrano I, Moiraghi A, Saini M, DiMeco F.

J Ultrasound. 2014 Jun 24;17(3):243-51. doi: 10.1007/s40477-014-0111-8. eCollection 2014 Sep.


Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.

Wicks RT, Azadi J, Mangraviti A, Zhang I, Hwang L, Joshi A, Bow H, Hutt-Cabezas M, Martin KL, Rudek MA, Zhao M, Brem H, Tyler BM.

Neuro Oncol. 2015 Jan;17(1):70-80. doi: 10.1093/neuonc/nou143. Epub 2014 Jul 22.


Quantitative multiparametric MRI assessment of glioma response to radiotherapy in a rat model.

Hong X, Liu L, Wang M, Ding K, Fan Y, Ma B, Lal B, Tyler B, Mangraviti A, Wang S, Wong J, Laterra J, Zhou J.

Neuro Oncol. 2014 Jun;16(6):856-67. doi: 10.1093/neuonc/not245. Epub 2013 Dec 22.


Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models.

Grossman R, Brastianos H, Blakeley JO, Mangraviti A, Lal B, Zadnik P, Hwang L, Wicks RT, Goodwin RC, Brem H, Tyler B.

J Neurooncol. 2014 Jan;116(1):59-65. doi: 10.1007/s11060-013-1268-2. Epub 2013 Nov 2.


Craniotomy vs. craniectomy for posterior fossa tumors: a prospective study to evaluate complications after surgery.

Legnani FG, Saladino A, Casali C, Vetrano IG, Varisco M, Mattei L, Prada F, Perin A, Mangraviti A, Solero CL, DiMeco F.

Acta Neurochir (Wien). 2013 Dec;155(12):2281-6.


Practical assessment of preoperative functional mapping techniques: navigated transcranial magnetic stimulation and functional magnetic resonance imaging.

Mangraviti A, Casali C, Cordella R, Legnani FG, Mattei L, Prada F, Saladino A, Contarino VE, Perin A, DiMeco F.

Neurol Sci. 2013 Sep;34(9):1551-7. doi: 10.1007/s10072-012-1283-7. Epub 2012 Dec 25. Erratum in: Neurol Sci. 2014 Mar;35(3):501. Contarino, Valeria Elisa [added].


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