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Items: 1 to 50 of 229

1.

Inorganic gold and polymeric poly(lactide-co-glycolide) nanoparticles as novel strategies to ameliorate the biological properties of antimicrobial peptides.

Casciaro B, Ghirga F, Quaglio D, Mangoni ML.

Curr Protein Pept Sci. 2019 Dec 2. doi: 10.2174/1389203720666191203101947. [Epub ahead of print]

PMID:
31797755
2.

Aggregation determines the selectivity of membrane-active anticancer and antimicrobial peptides: The case of killerFLIP.

Vaezi Z, Bortolotti A, Luca V, Perilli G, Mangoni ML, Khosravi-Far R, Bobone S, Stella L.

Biochim Biophys Acta Biomembr. 2019 Oct 31:183107. doi: 10.1016/j.bbamem.2019.183107. [Epub ahead of print]

PMID:
31678022
3.

Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of Staphylococcus aureus-Induced Infections.

Casciaro B, Calcaterra A, Cappiello F, Mori M, Loffredo MR, Ghirga F, Mangoni ML, Botta B, Quaglio D.

Toxins (Basel). 2019 Sep 1;11(9). pii: E511. doi: 10.3390/toxins11090511.

4.

The Potential of Frog Skin Peptides for Anti-Infective Therapies: the Case of Esculentin-1a(1-21)NH2.

Casciaro B, Cappiello F, Loffredo MR, Ghirga F, Mangoni ML.

Curr Med Chem. 2019 Jul 21. doi: 10.2174/0929867326666190722095408. [Epub ahead of print]

PMID:
31333082
5.

Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH2.

Casciaro B, Lin Q, Afonin S, Loffredo MR, de Turris V, Middel V, Ulrich AS, Di YP, Mangoni ML.

FEBS J. 2019 Oct;286(19):3874-3891. doi: 10.1111/febs.14940. Epub 2019 Jun 13.

PMID:
31144441
6.

The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L.

Buommino E, Carotenuto A, Antignano I, Bellavita R, Casciaro B, Loffredo MR, Merlino F, Novellino E, Mangoni ML, Nocera FP, Brancaccio D, Punzi P, Roversi D, Ingenito R, Bianchi E, Grieco P.

ChemMedChem. 2019 Jul 3;14(13):1283-1290. doi: 10.1002/cmdc.201900221. Epub 2019 Jun 3.

PMID:
31087626
7.

Poly(lactide- co-glycolide) Nanoparticles for Prolonged Therapeutic Efficacy of Esculentin-1a-Derived Antimicrobial Peptides against Pseudomonas aeruginosa Lung Infection: in Vitro and in Vivo Studies.

Casciaro B, d'Angelo I, Zhang X, Loffredo MR, Conte G, Cappiello F, Quaglia F, Di YP, Ungaro F, Mangoni ML.

Biomacromolecules. 2019 May 13;20(5):1876-1888. doi: 10.1021/acs.biomac.8b01829. Epub 2019 Apr 23.

PMID:
31013061
8.

Esculentin-1a Derived Antipseudomonal Peptides: Limited Induction of Resistance and Synergy with Aztreonam.

Casciaro B, Loffredo MR, Luca V, Verrusio W, Cacciafesta M, Mangoni ML.

Protein Pept Lett. 2018;25(12):1155-1162. doi: 10.2174/0929866525666181101104649.

PMID:
30381056
9.

[Genesis of cardiac sinus automaticity and therapeutic perspectives].

Mesirca P, Torrente AG, Bidaud I, Baudot M, Nargeot J, Mangoni ME.

Arch Mal Coeur Vaiss Pratique. 2018 Apr;2018(267):35-39. doi: 10.1016/j.amcp.2018.02.007. Epub 2018 Mar 12. French. No abstract available.

10.

Enhancement of Soft Tissue Sarcoma Cell Radiosensitivity by Poly(ADP-ribose) Polymerase-1 Inhibitors.

Mangoni M, Sottili M, Salvatore G, Meattini I, Desideri I, Greto D, Loi M, Becherini C, Garlatti P, Delli Paoli C, Dominici L, Gerini C, Scoccianti S, Bonomo P, Silvano A, Beltrami G, Campanacci D, Livi L.

Radiat Res. 2018 Nov;190(5):464-472. doi: 10.1667/RR15035.1. Epub 2018 Aug 1.

PMID:
30067444
11.

Peptidomic analysis of the host-defense peptides in skin secretions of the Trinidadian leaf frog Phyllomedusa trinitatis (Phyllomedusidae).

Mechkarska M, Coquet L, Leprince J, Auguste RJ, Jouenne T, Mangoni ML, Conlon JM.

Comp Biochem Physiol Part D Genomics Proteomics. 2018 Dec;28:72-79. doi: 10.1016/j.cbd.2018.06.006. Epub 2018 Jun 30.

PMID:
29980138
12.

A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A.

Elife. 2018 Jun 20;7. pii: e35753. doi: 10.7554/eLife.35753.

13.

Re-irradiation as salvage treatment in recurrent glioblastoma: A comprehensive literature review to provide practical answers to frequently asked questions.

Scoccianti S, Francolini G, Carta GA, Greto D, Detti B, Simontacchi G, Visani L, Baki M, Poggesi L, Bonomo P, Mangoni M, Desideri I, Pallotta S, Livi L.

Crit Rev Oncol Hematol. 2018 Jun;126:80-91. doi: 10.1016/j.critrevonc.2018.03.024. Epub 2018 Mar 31. Review.

PMID:
29759570
14.

Safety of concurrent adjuvant radiotherapy and chemotherapy for locally advanced soft tissue sarcoma.

Greto D, Loi M, Saieva C, Muntoni C, Delli Paoli C, Becherini C, Ciabatti C, Perna M, Campanacci D, Terziani F, Beltrami G, Scoccianti G, Bonomo P, Meattini I, Desideri I, Simontacchi G, Mangoni M, Livi L.

Tumori. 2018 Oct;104(5):322-329. doi: 10.1177/0300891618765565. Epub 2018 Apr 11.

PMID:
29714662
15.

A Novel In Vitro Wound Healing Assay to Evaluate Cell Migration.

Cappiello F, Casciaro B, Mangoni ML.

J Vis Exp. 2018 Mar 17;(133). doi: 10.3791/56825.

PMID:
29608162
16.

Anti PD-L1 DUrvalumab combined with Cetuximab and RadiOtherapy in locally advanced squamous cell carcinoma of the head and neck: A phase I/II study (DUCRO).

Bonomo P, Desideri I, Loi M, Mangoni M, Sottili M, Marrazzo L, Talamonti C, Greto D, Pallotta S, Livi L.

Clin Transl Radiat Oncol. 2018 Feb 7;9:42-47. doi: 10.1016/j.ctro.2018.01.005. eCollection 2018 Feb.

17.

Soft tissue sarcomas: new opportunity of treatment with PARP inhibitors?

Mangoni M, Sottili M, Salvatore G, Campanacci D, Scoccianti G, Beltrami G, Delli Paoli C, Dominici L, Maragna V, Olmetto E, Meattini I, Desideri I, Bonomo P, Greto D, Livi L.

Radiol Med. 2019 Apr;124(4):282-289. doi: 10.1007/s11547-018-0877-4. Epub 2018 Mar 26. Review.

PMID:
29582320
18.

Triple Negative Apocrine Carcinomas as a Distinct Subtype of Triple Negative Breast Cancer: A Case-control Study.

Meattini I, Pezzulla D, Saieva C, Bernini M, Orzalesi L, Sanchez LJ, Desideri I, Francolini G, Bonomo P, Greto D, Loi M, Mangoni M, Bruni A, Nori J, Vezzosi V, Bianchi S, Livi L.

Clin Breast Cancer. 2018 Oct;18(5):e773-e780. doi: 10.1016/j.clbc.2018.02.012. Epub 2018 Mar 2.

PMID:
29573977
19.

Targeting LMW-PTP to sensitize melanoma cancer cells toward chemo- and radiotherapy.

Lori G, Paoli P, Caselli A, Cirri P, Marzocchini R, Mangoni M, Talamonti C, Livi L, Raugei G.

Cancer Med. 2018 May;7(5):1933-1943. doi: 10.1002/cam4.1435. Epub 2018 Mar 24.

20.

Insulinotropic, glucose-lowering, and beta-cell anti-apoptotic actions of peptides related to esculentin-1a(1-21).NH2.

Musale V, Abdel-Wahab YHA, Flatt PR, Conlon JM, Mangoni ML.

Amino Acids. 2018 Jun;50(6):723-734. doi: 10.1007/s00726-018-2551-5. Epub 2018 Mar 17.

PMID:
29549522
21.

The Amphibian Antimicrobial Peptide Temporin B Inhibits In Vitro Herpes Simplex Virus 1 Infection.

Marcocci ME, Amatore D, Villa S, Casciaro B, Aimola P, Franci G, Grieco P, Galdiero M, Palamara AT, Mangoni ML, Nencioni L.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02367-17. doi: 10.1128/AAC.02367-17. Print 2018 May.

22.

A new standardized data collection system for interdisciplinary thyroid cancer management: Thyroid COBRA.

Tagliaferri L, Gobitti C, Colloca GF, Boldrini L, Farina E, Furlan C, Paiar F, Vianello F, Basso M, Cerizza L, Monari F, Simontacchi G, Gambacorta MA, Lenkowicz J, Dinapoli N, Lanzotti V, Mazzarotto R, Russi E, Mangoni M.

Eur J Intern Med. 2018 Jul;53:73-78. doi: 10.1016/j.ejim.2018.02.012. Epub 2018 Feb 21.

PMID:
29477755
23.

Assessment of the potential of temporin peptides from the frog Rana temporaria (Ranidae) as anti-diabetic agents.

Musale V, Casciaro B, Mangoni ML, Abdel-Wahab YHA, Flatt PR, Conlon JM.

J Pept Sci. 2018 Feb;24(2). doi: 10.1002/psc.3065. Epub 2018 Jan 19.

PMID:
29349894
24.

Incidence of skin toxicity in squamous cell carcinoma of the head and neck treated with radiotherapy and cetuximab: A systematic review.

Bonomo P, Loi M, Desideri I, Olmetto E, Delli Paoli C, Terziani F, Greto D, Mangoni M, Scoccianti S, Simontacchi G, Francolini G, Meattini I, Caini S, Livi L.

Crit Rev Oncol Hematol. 2017 Dec;120:98-110. doi: 10.1016/j.critrevonc.2017.10.011. Epub 2017 Oct 31. Review.

PMID:
29198343
25.

Peroxisome proliferator activated receptor-gamma stimulation for prevention of 5-fluorouracil-induced oral mucositis in mice.

Sottili M, Mangoni M, Gerini C, Salvatore G, Castiglione F, Desideri I, Bonomo P, Meattini I, Greto D, Loi M, Francolini G, Perna M, Grassi R, Biti G, Livi L.

Head Neck. 2018 Mar;40(3):577-583. doi: 10.1002/hed.25017. Epub 2017 Nov 20.

PMID:
29155481
26.

Esculentin-1a derived peptides kill Pseudomonas aeruginosa biofilm on soft contact lenses and retain antibacterial activity upon immobilization to the lens surface.

Casciaro B, Dutta D, Loffredo MR, Marcheggiani S, McDermott AM, Willcox MD, Mangoni ML.

Biopolymers. 2017 Oct 31. doi: 10.1002/bip.23074. [Epub ahead of print]

PMID:
29086910
27.

Clock-dependent and system-driven oscillators interact in the suprachiasmatic nuclei to pace mammalian circadian rhythms.

Abitbol K, Debiesse S, Molino F, Mesirca P, Bidaud I, Minami Y, Mangoni ME, Yagita K, Mollard P, Bonnefont X.

PLoS One. 2017 Oct 23;12(10):e0187001. doi: 10.1371/journal.pone.0187001. eCollection 2017.

28.

Peptidomic analysis of skin secretions of the Mexican burrowing toad Rhinophrynus dorsalis (Rhinophrynidae): Insight into the origin of host-defense peptides within the Pipidae and characterization of a proline-arginine-rich peptide.

Conlon JM, Guilhaudis L, Leprince J, Coquet L, Mangoni ML, Attoub S, Jouenne T, King JD.

Peptides. 2017 Nov;97:22-28. doi: 10.1016/j.peptides.2017.09.012. Epub 2017 Sep 23.

PMID:
28951157
29.

Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NH2 and its Diastereomer Esc(1-21)-1c: Correlation with their antipseudomonal and cytotoxic activity.

Loffredo MR, Ghosh A, Harmouche N, Casciaro B, Luca V, Bortolotti A, Cappiello F, Stella L, Bhunia A, Bechinger B, Mangoni ML.

Biochim Biophys Acta Biomembr. 2017 Dec;1859(12):2327-2339. doi: 10.1016/j.bbamem.2017.09.009. Epub 2017 Sep 12.

30.

Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities.

Merlino F, Carotenuto A, Casciaro B, Martora F, Loffredo MR, Di Grazia A, Yousif AM, Brancaccio D, Palomba L, Novellino E, Galdiero M, Iovene MR, Mangoni ML, Grieco P.

Eur J Med Chem. 2017 Oct 20;139:750-761. doi: 10.1016/j.ejmech.2017.08.040. Epub 2017 Aug 21.

PMID:
28863356
31.

In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection.

Chen C, Mangoni ML, Di YP.

Sci Rep. 2017 Aug 17;7(1):8548. doi: 10.1038/s41598-017-08361-8.

32.

CaV1.3 L-type Ca2+ channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na+ current.

Toyoda F, Mesirca P, Dubel S, Ding WG, Striessnig J, Mangoni ME, Matsuura H.

Sci Rep. 2017 Aug 11;7(1):7869. doi: 10.1038/s41598-017-08191-8.

33.

Cytotoxic peptides with insulin-releasing activities from skin secretions of the Italian stream frog Rana italica (Ranidae).

Conlon JM, Musale V, Attoub S, Mangoni ML, Leprince J, Coquet L, Jouenne T, Abdel-Wahab YHA, Flatt PR, Rinaldi AC.

J Pept Sci. 2017 Oct;23(10):769-776. doi: 10.1002/psc.3025. Epub 2017 Jul 11.

PMID:
28699258
34.

Promising Approaches to Optimize the Biological Properties of the Antimicrobial Peptide Esculentin-1a(1-21)NH2: Amino Acids Substitution and Conjugation to Nanoparticles.

Casciaro B, Cappiello F, Cacciafesta M, Mangoni ML.

Front Chem. 2017 Apr 25;5:26. doi: 10.3389/fchem.2017.00026. eCollection 2017. Review.

35.

RyR2R420Q catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism.

Wang YY, Mesirca P, Marqués-Sulé E, Zahradnikova A Jr, Villejoubert O, D'Ocon P, Ruiz C, Domingo D, Zorio E, Mangoni ME, Benitah JP, Gómez AM.

JCI Insight. 2017 Apr 20;2(8). pii: 91872. doi: 10.1172/jci.insight.91872. eCollection 2017 Apr 20.

36.

A PPAR-gamma agonist protects from radiation-induced intestinal toxicity.

Mangoni M, Sottili M, Gerini C, Desideri I, Bastida C, Pallotta S, Castiglione F, Bonomo P, Meattini I, Greto D, Cappelli S, Di Brina L, Loi M, Biti G, Livi L.

United European Gastroenterol J. 2017 Mar;5(2):218-226. doi: 10.1177/2050640616640443. Epub 2016 Jul 8.

37.

Radiotherapy in the age of cancer immunology: Current concepts and future developments.

Loi M, Desideri I, Greto D, Mangoni M, Sottili M, Meattini I, Becherini C, Terziani F, Delli Paoli C, Olmetto E, Bonomo P, Livi L.

Crit Rev Oncol Hematol. 2017 Apr;112:1-10. doi: 10.1016/j.critrevonc.2017.02.002. Epub 2017 Feb 7. Review.

PMID:
28325250
38.

A PPAR gamma agonist protects against oral mucositis induced by irradiation in a murine model.

Mangoni M, Sottili M, Gerini C, Desideri I, Bastida C, Pallotta S, Castiglione F, Bonomo P, Meattini I, Greto D, Olmetto E, Terziani F, Becherini C, Delli Paoli C, Trombetta L, Loi M, Biti G, Livi L.

Oral Oncol. 2017 Jan;64:52-58. doi: 10.1016/j.oraloncology.2016.11.018. Epub 2016 Dec 3.

PMID:
28024724
39.

Methods for In Vivo/Ex Vivo Analysis of Antimicrobial Peptides in Bacterial Keratitis: siRNA Knockdown, Colony Counts, Myeloperoxidase, Immunostaining, and RT-PCR Assays.

Kolar SS, Baidouri H, Mangoni ML, McDermott AM.

Methods Mol Biol. 2017;1548:411-425. doi: 10.1007/978-1-4939-6737-7_30.

PMID:
28013522
40.

Methods for In Vitro Analysis of Antimicrobial Activity and Toxicity of Anti-keratitis Peptides: Bacterial Viability in Tears, MTT, and TNF-α Release Assays.

Cappiello F, Casciaro B, Kolar SS, Baidouri H, McDermott AM, Mangoni ML.

Methods Mol Biol. 2017;1548:395-409. doi: 10.1007/978-1-4939-6737-7_29.

PMID:
28013521
41.

Cell-Density Dependence of Host-Defense Peptide Activity and Selectivity in the Presence of Host Cells.

Savini F, Luca V, Bocedi A, Massoud R, Park Y, Mangoni ML, Stella L.

ACS Chem Biol. 2017 Jan 20;12(1):52-56. doi: 10.1021/acschembio.6b00910. Epub 2016 Dec 9.

42.

Impact of molecular subtypes classification concordance between preoperative core needle biopsy and surgical specimen on early breast cancer management: Single-institution experience and review of published literature.

Meattini I, Bicchierai G, Saieva C, De Benedetto D, Desideri I, Becherini C, Abdulcadir D, Vanzi E, Boeri C, Gabbrielli S, Lucci F, Sanchez L, Casella D, Bernini M, Orzalesi L, Vezzosi V, Greto D, Mangoni M, Bianchi S, Livi L, Nori J.

Eur J Surg Oncol. 2017 Apr;43(4):642-648. doi: 10.1016/j.ejso.2016.10.025. Epub 2016 Nov 17. Review.

PMID:
27889196
43.

Effects of Aib residues insertion on the structural-functional properties of the frog skin-derived peptide esculentin-1a(1-21)NH2.

Biondi B, Casciaro B, Di Grazia A, Cappiello F, Luca V, Crisma M, Mangoni ML.

Amino Acids. 2017 Jan;49(1):139-150. doi: 10.1007/s00726-016-2341-x. Epub 2016 Oct 11.

PMID:
27726008
44.

Gold-nanoparticles coated with the antimicrobial peptide esculentin-1a(1-21)NH2 as a reliable strategy for antipseudomonal drugs.

Casciaro B, Moros M, Rivera-Fernández S, Bellelli A, de la Fuente JM, Mangoni ML.

Acta Biomater. 2017 Jan 1;47:170-181. doi: 10.1016/j.actbio.2016.09.041. Epub 2016 Sep 29.

PMID:
27693686
45.

Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action.

Cappiello F, Di Grazia A, Segev-Zarko LA, Scali S, Ferrera L, Galietta L, Pini A, Shai Y, Di YP, Mangoni ML.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7252-7262. Print 2016 Dec.

46.

External beam radiotherapy in thyroid carcinoma: clinical review and recommendations of the AIRO "Radioterapia Metabolica" Group.

Mangoni M, Gobitti C, Autorino R, Cerizza L, Furlan C, Mazzarotto R, Monari F, Simontacchi G, Vianello F, Basso M, Zanirato Rambaldi G, Russi E, Tagliaferri L.

Tumori. 2017 Mar 24;103(2):114-123. doi: 10.5301/tj.5000532. Epub 2016 Sep 1. Review.

PMID:
27647221
47.

Purification, Conformational Analysis, and Properties of a Family of Tigerinin Peptides from Skin Secretions of the Crowned Bullfrog Hoplobatrachus occipitalis.

McLaughlin CM, Lampis S, Mechkarska M, Coquet L, Jouenne T, King JD, Mangoni ML, Lukic ML, Scorciapino MA, Conlon JM.

J Nat Prod. 2016 Sep 23;79(9):2350-6. doi: 10.1021/acs.jnatprod.6b00494. Epub 2016 Aug 25.

PMID:
27560386
48.

Rescuing cardiac automaticity in L-type Cav1.3 channelopathies and beyond.

Mesirca P, Bidaud I, Mangoni ME.

J Physiol. 2016 Oct 15;594(20):5869-5879. doi: 10.1113/JP270678. Epub 2016 Aug 2. Review.

49.

Desmosomes and sino-atrial dysfunction.

Mangoni ME.

Cardiovasc Res. 2016 Aug 1;111(3):167-8. doi: 10.1093/cvr/cvw171. Epub 2016 Jun 19. No abstract available.

PMID:
27325669
50.

Post-ABVD/pre-radiotherapy (18)F-FDG-PET provides additional prognostic information for early-stage Hodgkin lymphoma: a retrospective analysis on 165 patients.

Ciammella P, Filippi AR, Simontacchi G, Buglione M, Botto B, Mangoni M, Iotti C, Merli F, Marcheselli L, Bisi G, Ricardi U, Versari A.

Br J Radiol. 2016;89(1061):20150983. doi: 10.1259/bjr.20150983. Epub 2016 Mar 24.

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