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Items: 11

1.

Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity.

Mangan PR, Su LJ, Jenny V, Tatum AL, Picarillo C, Skala S, Ditto N, Lin Z, Yang X, Cotter PZ, Shuster DJ, Song Y, Borowski V, Thomas RL, Heimrich EM, Devaux B, Das Gupta R, Carvajal I, McIntyre KW, Xie J, Zhao Q, Struthers M, Salter-Cid LM.

J Pharmacol Exp Ther. 2015 Aug;354(2):152-65. doi: 10.1124/jpet.115.224246. Epub 2015 May 26.

PMID:
26015463
2.

Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production.

Sonnenberg GF, Mangan PR, Bezman NA, Sekiguchi DR, Luning Prak ET, Erikson J, Maltzman JS, Jordan MS, Koretzky GA.

Blood. 2010 Mar 18;115(11):2186-95. doi: 10.1182/blood-2009-08-237438. Epub 2009 Dec 22.

3.

IL-17 family cytokines and the expanding diversity of effector T cell lineages.

Weaver CT, Hatton RD, Mangan PR, Harrington LE.

Annu Rev Immunol. 2007;25:821-52. Review.

PMID:
17201677
4.

Th17: an effector CD4 T cell lineage with regulatory T cell ties.

Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Murphy KM.

Immunity. 2006 Jun;24(6):677-88. Review.

5.

Transforming growth factor-beta induces development of the T(H)17 lineage.

Mangan PR, Harrington LE, O'Quinn DB, Helms WS, Bullard DC, Elson CO, Hatton RD, Wahl SM, Schoeb TR, Weaver CT.

Nature. 2006 May 11;441(7090):231-4. Epub 2006 Apr 30.

PMID:
16648837
6.

Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

Harrington LE, Mangan PR, Weaver CT.

Curr Opin Immunol. 2006 Jun;18(3):349-56. Epub 2006 Apr 17. Review.

PMID:
16616472
7.

Both Th1 and Th2 cells require P-selectin glycoprotein ligand-1 for optimal rolling on inflamed endothelium.

Mangan PR, O'Quinn D, Harrington L, Bonder CS, Kubes P, Kucik DF, Bullard DC, Weaver CT.

Am J Pathol. 2005 Dec;167(6):1661-75.

8.

P-selectin can support both Th1 and Th2 lymphocyte rolling in the intestinal microvasculature.

Bonder CS, Norman MU, Macrae T, Mangan PR, Weaver CT, Bullard DC, McCafferty DM, Kubes P.

Am J Pathol. 2005 Dec;167(6):1647-60.

9.

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages.

Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT.

Nat Immunol. 2005 Nov;6(11):1123-32. Epub 2005 Oct 2.

10.

Raloxifene-mediated increase in matrix metalloproteinase-1 production by activated monocytes.

Ardans JA, Blum A, Mangan PR, Wientroub S, Cannon RO 3rd, Wahl LM.

Arterioscler Thromb Vasc Biol. 2001 Aug;21(8):1265-8.

PMID:
11498451
11.

Monocyte membrane type 1-matrix metalloproteinase. Prostaglandin-dependent regulation and role in metalloproteinase-2 activation.

Shankavaram UT, Lai WC, Netzel-Arnett S, Mangan PR, Ardans JA, Caterina N, Stetler-Stevenson WG, Birkedal-Hansen H, Wahl LM.

J Biol Chem. 2001 Jun 1;276(22):19027-32. Epub 2001 Mar 20.

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