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Items: 23


Prevotella histicola, A Human Gut Commensal, Is as Potent as COPAXONE® in an Animal Model of Multiple Sclerosis.

Shahi SK, Freedman SN, Murra AC, Zarei K, Sompallae R, Gibson-Corley KN, Karandikar NJ, Murray JA, Mangalam AK.

Front Immunol. 2019 Mar 22;10:462. doi: 10.3389/fimmu.2019.00462. eCollection 2019.


Drugs, bugs, and MS: The interplay between disease-modifying therapy and gut microbiota.

Mangalam AK.

Neurol Neuroimmunol Neuroinflamm. 2018 Nov 27;6(1):e524. doi: 10.1212/NXI.0000000000000524. eCollection 2019 Jan. No abstract available.


The "Gut Feeling": Breaking Down the Role of Gut Microbiome in Multiple Sclerosis.

Freedman SN, Shahi SK, Mangalam AK.

Neurotherapeutics. 2018 Jan;15(1):109-125. doi: 10.1007/s13311-017-0588-x. Review.


Gut microbiome in multiple sclerosis: The players involved and the roles they play.

Shahi SK, Freedman SN, Mangalam AK.

Gut Microbes. 2017 Nov 2;8(6):607-615. doi: 10.1080/19490976.2017.1349041. Epub 2017 Aug 3. Review.


Neuropilin-1 modulates interferon-╬│-stimulated signaling in brain microvascular endothelial cells.

Wang Y, Cao Y, Mangalam AK, Guo Y, LaFrance-Corey RG, Gamez JD, Atanga PA, Clarkson BD, Zhang Y, Wang E, Angom RS, Dutta K, Ji B, Pirko I, Lucchinetti CF, Howe CL, Mukhopadhyay D.

J Cell Sci. 2016 Oct 15;129(20):3911-3921. Epub 2016 Sep 2.


AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage-Th17 Axis.

Mangalam AK, Rattan R, Suhail H, Singh J, Hoda MN, Deshpande M, Fulzele S, Denic A, Shridhar V, Kumar A, Viollet B, Rodriguez M, Giri S.

J Immunol. 2016 Aug 1;197(3):747-60. doi: 10.4049/jimmunol.1501549. Epub 2016 Jun 27.


Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls.

Chen J, Chia N, Kalari KR, Yao JZ, Novotna M, Paz Soldan MM, Luckey DH, Marietta EV, Jeraldo PR, Chen X, Weinshenker BG, Rodriguez M, Kantarci OH, Nelson H, Murray JA, Mangalam AK.

Sci Rep. 2016 Jun 27;6:28484. doi: 10.1038/srep28484.


Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses.

Zhao J, Zhao J, Mangalam AK, Channappanavar R, Fett C, Meyerholz DK, Agnihothram S, Baric RS, David CS, Perlman S.

Immunity. 2016 Jun 21;44(6):1379-91. doi: 10.1016/j.immuni.2016.05.006. Epub 2016 Jun 7.


Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis.

Poisson LM, Suhail H, Singh J, Datta I, Denic A, Labuzek K, Hoda MN, Shankar A, Kumar A, Cerghet M, Elias S, Mohney RP, Rodriguez M, Rattan R, Mangalam AK, Giri S.

J Biol Chem. 2015 Dec 25;290(52):30697-712. doi: 10.1074/jbc.M115.679068. Epub 2015 Nov 6.


Modulation of Immune response by Ultra-violet light in HLA class-II transgenic mice.

Blanco DB, Luckey D, Smart M, Pittelkow M, Kumar R, David CS, Mangalam AK.

Jacobs J Allergy Immunol. 2014 Dec;1(1). pii: 007.


Absence of IFN-╬│ increases brain pathology in experimental autoimmune encephalomyelitis-susceptible DRB1*0301.DQ8 HLA transgenic mice through secretion of proinflammatory cytokine IL-17 and induction of pathogenic monocytes/microglia into the central nervous system.

Mangalam AK, Luo N, Luckey D, Papke L, Hubbard A, Wussow A, Smart M, Giri S, Rodriguez M, David C.

J Immunol. 2014 Nov 15;193(10):4859-70. doi: 10.4049/jimmunol.1302008. Epub 2014 Oct 22.


Profile of Circulatory Metabolites in a Relapsing-remitting Animal Model of Multiple Sclerosis using Global Metabolomics.

Mangalam A, Poisson L, Nemutlu E, Datta I, Denic A, Dzeja P, Rodriguez M, Rattan R, Giri S.

J Clin Cell Immunol. 2013 Jun 30;4. doi: 10.4172/2155-9899.1000150.


HLA class II molecules influence susceptibility versus protection in inflammatory diseases by determining the cytokine profile.

Mangalam AK, Taneja V, David CS.

J Immunol. 2013 Jan 15;190(2):513-8. doi: 10.4049/jimmunol.1201891. Review.


WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.

Piotrowski JT, Gomez TS, Schoon RA, Mangalam AK, Billadeau DD.

Mol Cell Biol. 2013 Mar;33(5):958-73. doi: 10.1128/MCB.01288-12. Epub 2012 Dec 28.


Two discreet subsets of CD8 T cells modulate PLP(91-110) induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice.

Mangalam AK, Luckey D, Giri S, Smart M, Pease LR, Rodriguez M, David CS.

J Autoimmun. 2012 Jun;38(4):344-53. doi: 10.1016/j.jaut.2012.02.004. Epub 2012 Mar 28.


Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: studies using HLA transgenic mice.

Luckey D, Bastakoty D, Mangalam AK.

J Autoimmun. 2011 Sep;37(2):122-8. doi: 10.1016/j.jaut.2011.05.001. Epub 2011 May 31. Review.


HLA class II transgenic mice mimic human inflammatory diseases.

Mangalam AK, Rajagopalan G, Taneja V, David CS.

Adv Immunol. 2008;97:65-147. doi: 10.1016/S0065-2776(08)00002-3. Review.


Autoimmunity in HLA-DQ8 transgenic mice expressing granulocyte/macrophage-colony stimulating factor in the beta cells of islets of Langerhans.

Rajagopalan G, Mangalam AK, Sen MM, Cheng S, Kudva YC, David CS.

Autoimmunity. 2007 May;40(3):169-79.


Mechanism of action of disease modifying anti-rheumatic agent, gold sodium thiomalate (GSTM).

Mangalam AK, Aggarwal A, Naik S.

Int Immunopharmacol. 2001 Jun;1(6):1165-72.


Primer premier: program for design of degenerate primers from a protein sequence.

Singh VK, Mangalam AK, Dwivedi S, Naik S.

Biotechniques. 1998 Feb;24(2):318-9. No abstract available.

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