Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 59

1.

Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis.

Scanio MJC, Searle XB, Liu B, Koenig JR, Altenbach R, Gfesser GA, Bogdan A, Greszler S, Zhao G, Singh A, Fan Y, Swensen AM, Vortherms T, Manelli A, Balut C, Jia Y, Gao W, Yong H, Schrimpf M, Tse C, Kym P, Wang X.

ACS Med Chem Lett. 2019 Oct 31;10(11):1543-1548. doi: 10.1021/acsmedchemlett.9b00377. eCollection 2019 Nov 14.

PMID:
31749908
2.

Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222.

Singh AK, Fan Y, Balut C, Alani S, Manelli AM, Swensen AM, Jia Y, Neelands TR, Vortherms TA, Liu B, Searle XB, Wang X, Gao W, Hwang TC, Ren HY, Cyr D, Kym PR, Conrath K, Tse C.

J Pharmacol Exp Ther. 2020 Jan;372(1):107-118. doi: 10.1124/jpet.119.261800. Epub 2019 Nov 15.

PMID:
31732698
3.

Gait screening of a population of young, healthy athletes by means of a portable, low-cost device unveils hidden left-right asymmetries in both quadriceps and anterior cruciate ligament forces.

Colombo N, Vignaga F, Solari E, Merlo M, Manelli A, Negrini D, Moriondo A.

BMC Res Notes. 2019 Jun 28;12(1):366. doi: 10.1186/s13104-019-4406-x.

4.

Arterial and microvascular supply of cerebral hemispheres in the nude mouse revealed using corrosion casting and scanning electron microscopy.

Sangiorgi S, Benedictis A, Reguzzoni M, Trezza A, Cossu S, Marras CE, Bellocchi S, Manelli A, Protasoni M.

J Anat. 2018 May;232(5):739-746. doi: 10.1111/joa.12791. Epub 2018 Feb 14.

PMID:
29441571
5.

Acute metformin intoxication: 2012 experience of Emergency Departement of Lodi, Italy.

Acquistapace G, Rossi M, Garbi M, Cosci P, Canetta C, Manelli A, Ricevuti G.

Clin Chem Lab Med. 2014 Oct;52(10):1489-97. doi: 10.1515/cclm-2014-0208.

PMID:
24940713
6.

Early-stage microvascular alterations of a new model of controlled cortical traumatic brain injury: 3D morphological analysis using scanning electron microscopy and corrosion casting.

Sangiorgi S, De Benedictis A, Protasoni M, Manelli A, Reguzzoni M, Cividini A, Dell'orbo C, Tomei G, Balbi S.

J Neurosurg. 2013 Apr;118(4):763-74. doi: 10.3171/2012.11.JNS12627. Epub 2013 Jan 25.

PMID:
23350772
7.

Pharmacological characterization of A-960656, a histamine H₃ receptor antagonist with efficacy in animal models of osteoarthritis and neuropathic pain.

Cowart M, Hsieh G, Black LA, Zhan C, Gomez EJ, Pai M, Strakhova M, Manelli A, Carr T, Wetter J, Lee A, Diaz G, Garrison T, Brioni JD.

Eur J Pharmacol. 2012 Jun 5;684(1-3):87-94. doi: 10.1016/j.ejphar.2012.03.048. Epub 2012 Apr 5.

PMID:
22504024
8.

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.

Youmans KL, Tai LM, Kanekiyo T, Stine WB Jr, Michon SC, Nwabuisi-Heath E, Manelli AM, Fu Y, Riordan S, Eimer WA, Binder L, Bu G, Yu C, Hartley DM, LaDu MJ.

Mol Neurodegener. 2012 Mar 16;7:8. doi: 10.1186/1750-1326-7-8.

9.

Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain.

Altenbach RJ, Black LA, Strakhova MI, Manelli AM, Carr TL, Marsh KC, Wetter JM, Wensink EJ, Hsieh GC, Honore P, Garrison TR, Brioni JD, Cowart MD.

J Med Chem. 2010 Nov 11;53(21):7869-73. doi: 10.1021/jm100666w.

PMID:
20945906
10.

The cutaneous microvascular architecture of human diabetic toe studied by corrosion casting and scanning electron microscopy analysis.

Sangiorgi S, Manelli A, Reguzzoni M, Ronga M, Protasoni M, Dell'Orbo C.

Anat Rec (Hoboken). 2010 Oct;293(10):1639-45. doi: 10.1002/ar.21168. Epub 2010 Aug 4.

11.

In vitro studies on a class of quinoline containing histamine H3 antagonists.

Liu H, Altenbach RJ, Diaz GJ, Manelli AM, Martin RL, Miller TR, Esbenshade TA, Brioni JD, Cowart MD.

Bioorg Med Chem Lett. 2010 Jun 1;20(11):3295-300. doi: 10.1016/j.bmcl.2010.04.045. Epub 2010 Apr 18.

PMID:
20457525
12.

Rigidified 2-aminopyrimidines as histamine H4 receptor antagonists: effects of substitution about the rigidifying ring.

Koenig JR, Liu H, Drizin I, Witte DG, Carr TL, Manelli AM, Milicic I, Strakhova MI, Miller TR, Esbenshade TA, Brioni JD, Cowart M.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1900-4. doi: 10.1016/j.bmcl.2010.01.131. Epub 2010 Feb 1.

PMID:
20171098
13.

In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties.

Strakhova MI, Cuff CA, Manelli AM, Carr TL, Witte DG, Baranowski JL, Vortherms TA, Miller TR, Rundell L, McPherson MJ, Adair RM, Brito AA, Bettencourt BM, Yao BB, Wetter JM, Marsh KC, Liu H, Cowart MD, Brioni JD, Esbenshade TA.

Br J Pharmacol. 2009 May;157(1):44-54. doi: 10.1111/j.1476-5381.2009.00236.x.

14.

Localization of histamine H4 receptors in the central nervous system of human and rat.

Strakhova MI, Nikkel AL, Manelli AM, Hsieh GC, Esbenshade TA, Brioni JD, Bitner RS.

Brain Res. 2009 Jan 23;1250:41-8. doi: 10.1016/j.brainres.2008.11.018. Epub 2008 Nov 19.

PMID:
19046950
15.

cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

Liu H, Altenbach RJ, Carr TL, Chandran P, Hsieh GC, Lewis LG, Manelli AM, Milicic I, Marsh KC, Miller TR, Strakhova MI, Vortherms TA, Wakefield BD, Wetter JM, Witte DG, Honore P, Esbenshade TA, Brioni JD, Cowart MD.

J Med Chem. 2008 Nov 27;51(22):7094-8. doi: 10.1021/jm8007618.

PMID:
18983139
16.

Cloning and characterization of the monkey histamine H3 receptor isoforms.

Strakhova MI, Fox GB, Carr TL, Witte DG, Vortherms TA, Manelli AM, Miller TR, Yao BB, Brioni JD, Esbenshade TA.

Eur J Pharmacol. 2008 Dec 28;601(1-3):8-15. doi: 10.1016/j.ejphar.2008.10.026. Epub 2008 Oct 21.

PMID:
18977214
17.

A robust and high-capacity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands.

Miller TR, Baranowski JL, Estvander BR, Witte DG, Carr TL, Manelli AM, Krueger KM, Cowart MD, Brioni JD, Esbenshade TA.

Assay Drug Dev Technol. 2008 Jun;6(3):339-49. doi: 10.1089/adt.2007.118.

PMID:
18593375
18.

Gait analysis of pre- and post-meniscectomy knee: a prospective study.

Bulgheroni P, Bulgheroni MV, Ronga M, Manelli A.

Knee. 2007 Dec;14(6):472-7. Epub 2007 Oct 17.

PMID:
17942312
19.

3D analysis of SEM images of corrosion casting using adaptive stereo matching.

Manelli A, Sangiorgi S, Binaghi E, Raspanti M.

Microsc Res Tech. 2007 Apr;70(4):350-4.

PMID:
17262784
20.

Plexiform vascular structures in the human digital dermal layer: a SEM--corrosion casting morphological study.

Manelli A, Sangiorgi S, Ronga M, Reguzzoni M, Bini A, Raspanti M.

Eur J Morphol. 2005 Oct-Dec;42(4-5):173-7.

PMID:
16982473
21.

A new method for the joint visualization of vascular structures and connective tissues: corrosion casting and 1 N NaOH maceration.

Sangiorgi S, Manelli A, Dell'Orbo C, Congiu T.

Microsc Res Tech. 2006 Nov;69(11):919-23.

PMID:
16921528
22.

The three-dimensional microvascular architecture of the human Kaposi sarcoma implanted in nude mice: a SEM corrosion casting study.

Sangiorgi S, Congiu T, Manelli A, Dell'Eva R, Noonan DM.

Microvasc Res. 2006 Nov;72(3):128-35. Epub 2006 Aug 22.

PMID:
16920158
23.

Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation.

Manelli AM, Bulfinch LC, Sullivan PM, LaDu MJ.

Neurobiol Aging. 2007 Aug;28(8):1139-47. Epub 2006 Jul 11.

24.

Tissue engineering techniques for the treatment of a complex knee injury.

Ronga M, Grassi FA, Manelli A, Bulgheroni P.

Arthroscopy. 2006 May;22(5):576.e1-3.

PMID:
16651180
25.

Whiplash injury and oculomotor dysfunctions: clinical-posturographic correlations.

Storaci R, Manelli A, Schiavone N, Mangia L, Prigione G, Sangiorgi S.

Eur Spine J. 2006 Dec;15(12):1811-6. Epub 2006 Mar 22.

PMID:
16552533
26.

A new method to make vascular and bronchial casts of voluminous organs.

Viggiano D, Sangiorgi S, Reguzzoni M, Manelli A, Marano L, Dell'Orbo C, Passiatore C.

Eur J Morphol. 2003 Dec;41(5):161-5.

PMID:
16229158
27.

The microvasculature of the lateral choroid plexus in the rat: a scanning electron microscopy study of vascular corrosion casts.

Sangiorgi S, Picano M, Manelli A, Peron S, Tomei G, Raspanti M.

Eur J Morphol. 2003 Dec;41(5):155-60.

PMID:
16229157
28.

The 3D structure of crimps in the rat Achilles tendon.

Raspanti M, Manelli A, Franchi M, Ruggeri A.

Matrix Biol. 2005 Oct;24(7):503-7. Epub 2005 Aug 24.

PMID:
16125376
29.

The extracellular matrix of the human aortic wall: ultrastructural observations by FEG-SEM and by tapping-mode AFM.

Raspanti M, Protasoni M, Manelli A, Guizzardi S, Mantovani V, Sala A.

Micron. 2006;37(1):81-6. Epub 2005 Jul 13.

PMID:
16081297
30.

In situ hybridization by scanning electron microscopy for painting, centromeric, and YAC localization.

Reguzzoni M, Protasoni M, Maserati M, Pressato B, Manelli A, Raspanti M.

Arch Histol Cytol. 2005 Jun;68(2):115-20.

31.

A vision-based, 3D reconstruction technique for scanning electron microscopy: direct comparison with atomic force microscopy.

Raspanti M, Binaghi E, Gallo I, Manelli A.

Microsc Res Tech. 2005 May;67(1):1-7.

PMID:
16025484
32.

Histology and ultrastructure of a tissue-engineered collagen meniscus before and after implantation.

Reguzzoni M, Manelli A, Ronga M, Raspanti M, Grassi FA.

J Biomed Mater Res B Appl Biomater. 2005 Aug;74(2):808-16.

PMID:
15981176
33.

The collagenic structure of human digital skin seen by scanning electron microscopy after Ohtani maceration technique.

Sangiorgi S, Manelli A, Protasoni M, Ronga M, Raspanti M.

Ann Anat. 2005 Mar;187(1):13-22.

PMID:
15835396
34.

Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation.

White JA, Manelli AM, Holmberg KH, Van Eldik LJ, Ladu MJ.

Neurobiol Dis. 2005 Apr;18(3):459-65.

PMID:
15755672
35.

Isoform-specific effects of apolipoprotein E on secretion of inflammatory mediators in adult rat microglia.

Chen S, Averett NT, Manelli A, Ladu MJ, May W, Ard MD.

J Alzheimers Dis. 2005 Feb;7(1):25-35.

PMID:
15750212
36.

ApoE isoform-specific effects on LTP: blockade by oligomeric amyloid-beta1-42.

Trommer BL, Shah C, Yun SH, Gamkrelidze G, Pasternak ES, Stine WB, Manelli A, Sullivan P, Pasternak JF, LaDu MJ.

Neurobiol Dis. 2005 Feb;18(1):75-82.

PMID:
15649697
37.

Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein.

Irizarry MC, Deng A, Lleo A, Berezovska O, Von Arnim CA, Martin-Rehrmann M, Manelli A, LaDu MJ, Hyman BT, Rebeck GW.

J Neurochem. 2004 Sep;90(5):1132-43.

38.

ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function.

Manelli AM, Stine WB, Van Eldik LJ, LaDu MJ.

J Mol Neurosci. 2004;23(3):235-46. Review.

PMID:
15181252
39.

Structure and ultrastructure of microvessels in the kidney seen by the corrosion casting method.

Sangiorgi S, Manelli A, Protasoni M, Reguzzoni M, Congiu T, Raspanti M.

Ital J Anat Embryol. 2004 Jan-Mar;109(1):35-44.

PMID:
15141474
40.

Microvascularization of the human digit as studied by corrosion casting.

Sangiorgi S, Manelli A, Congiu T, Bini A, Pilato G, Reguzzoni M, Raspanti M.

J Anat. 2004 Feb;204(2):123-31.

41.

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

Dahlgren KN, Manelli AM, Stine WB Jr, Baker LK, Krafft GA, LaDu MJ.

J Biol Chem. 2002 Aug 30;277(35):32046-53. Epub 2002 Jun 10.

42.

[CT pulmonary density mapping: surgical utility].

Gavezzoli D, Caputo P, Manelli A, Zuccon W, Faccini M, Bonandrini L.

Minerva Chir. 2002 Apr;57(2):151-6. Italian.

PMID:
11941290
43.

[Hemorrhoids: epidemiology and correlation with chronic constipation].

Faccini M, Zuccon W, Caputo P, Gavezzoli D, Manelli A, Bonandrini L.

Ann Ital Chir. 2001 May-Jun;72(3):337-9; discussion 340. Italian.

PMID:
11765352
44.

[Hemorrhoid disease. Physiopathology, etiopathology and surgical approach].

Faccini M, Caputo P, Lavezzoli A, Manelli A, Bonandrini L.

Minerva Chir. 2000 Apr;55(4):253-9. Review. Italian.

PMID:
10859960
45.
46.

Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures.

Puttfarcken PS, Manelli AM, Falduto MT, Getz GS, LaDu MJ.

J Neurochem. 1997 Feb;68(2):760-9.

47.

The presence of the complement cascade does not lead to neuronal cell death in primary hippocampal cultures.

Manelli AM, Cadman ED, Shiosaki K, Puttfarcken PS.

Brain Res Bull. 1997;42(3):187-93.

PMID:
8995328
48.

Inhibition of age-induced beta-amyloid neurotoxicity in rat hippocampal cells.

Puttfarcken PS, Manelli AM, Neilly J, Frail DE.

Exp Neurol. 1996 Mar;138(1):73-81.

PMID:
8593898
49.

[Traumatic tearing of the mesentery: immediate or deferred emergency surgery].

Caputo P, Berti A, Manelli A, Palermo G, Parisi R, Safaee A, Zucchi G, Bonandrini L.

Minerva Chir. 1995 Apr;50(4):381-6. Italian.

PMID:
7675286
50.

Supplemental Content

Loading ...
Support Center