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Items: 1 to 50 of 57

1.

A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV.

Johnson JS, De Veaux N, Rives AW, Lahaye X, Lucas SY, Perot BP, Luka M, Garcia-Paredes V, Amon LM, Watters A, Abdessalem G, Aderem A, Manel N, Littman DR, Bonneau R, Ménager MM.

Cell Rep. 2020 Jan 21;30(3):914-931.e9. doi: 10.1016/j.celrep.2019.12.054.

2.

Clear cell gynecologic carcinomas: about 5 cases.

Haifa B, Ines Z, Manel N, Amira D, Sonia Z, Laila N, Houda M, Anis H, Raja F.

Pan Afr Med J. 2019 Oct 14;34:87. doi: 10.11604/pamj.2019.34.87.18505. eCollection 2019.

3.

Editorial overview: Pillars of innate immunity: constantly learning and trying to remember.

Manel N, Di Santo JP.

Curr Opin Immunol. 2019 Feb;56:iii-vi. doi: 10.1016/j.coi.2019.03.002. No abstract available.

PMID:
30981385
4.

Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS.

Gratia M, Rodero MP, Conrad C, Bou Samra E, Maurin M, Rice GI, Duffy D, Revy P, Petit F, Dale RC, Crow YJ, Amor-Gueret M, Manel N.

J Exp Med. 2019 May 6;216(5):1199-1213. doi: 10.1084/jem.20181329. Epub 2019 Apr 1.

5.

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.

Gentili M, Lahaye X, Nadalin F, Nader GPF, Lombardi EP, Herve S, De Silva NS, Rookhuizen DC, Zueva E, Goudot C, Maurin M, Bochnakian A, Amigorena S, Piel M, Fachinetti D, Londoño-Vallejo A, Manel N.

Cell Rep. 2019 Mar 26;26(13):3798. doi: 10.1016/j.celrep.2019.03.049. No abstract available.

6.

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.

Gentili M, Lahaye X, Nadalin F, Nader GPF, Puig Lombardi E, Herve S, De Silva NS, Rookhuizen DC, Zueva E, Goudot C, Maurin M, Bochnakian A, Amigorena S, Piel M, Fachinetti D, Londoño-Vallejo A, Manel N.

Cell Rep. 2019 Feb 26;26(9):2377-2393.e13. doi: 10.1016/j.celrep.2019.01.105. Erratum in: Cell Rep. 2019 Mar 26;26(13):3798.

7.

NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation.

Lahaye X, Gentili M, Silvin A, Conrad C, Picard L, Jouve M, Zueva E, Maurin M, Nadalin F, Knott GJ, Zhao B, Du F, Rio M, Amiel J, Fox AH, Li P, Etienne L, Bond CS, Colleaux L, Manel N.

Cell. 2018 Oct 4;175(2):488-501.e22. doi: 10.1016/j.cell.2018.08.062. Epub 2018 Sep 27.

8.

Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes.

Verrier ER, Yim SA, Heydmann L, El Saghire H, Bach C, Turon-Lagot V, Mailly L, Durand SC, Lucifora J, Durantel D, Pessaux P, Manel N, Hirsch I, Zeisel MB, Pochet N, Schuster C, Baumert TF.

Hepatology. 2018 Nov;68(5):1695-1709. doi: 10.1002/hep.30054. Epub 2018 Jul 10.

9.

Let me in: Control of HIV nuclear entry at the nuclear envelope.

Bhargava A, Lahaye X, Manel N.

Cytokine Growth Factor Rev. 2018 Apr;40:59-67. doi: 10.1016/j.cytogfr.2018.02.006. Epub 2018 Feb 27. Review.

PMID:
29526438
10.

Complete pathologic response after chemoradiotherapy in a patient with rectal squamous cell carcinoma: a case report.

Sonia Z, Amira D, Hanene B, Nouha A, Wiem K, Omar T, Ibtissem A, Salem Amina B, Manel N, Houda M.

Cancer Biol Med. 2017 Nov;14(4):414-417. doi: 10.20892/j.issn.2095-3941.2017.0010.

11.

Immune Responses to Retroviruses.

Sáez-Cirión A, Manel N.

Annu Rev Immunol. 2018 Apr 26;36:193-220. doi: 10.1146/annurev-immunol-051116-052155. Epub 2018 Jan 12. Review.

PMID:
29328787
12.

Mechanisms behind TB, HBV, and HIV chronic infections.

Durantel D, Kusters I, Louis J, Manel N, Ottenhoff THM, Picot V, Saaadatian-Elahi M.

Infect Genet Evol. 2017 Nov;55:142-150. doi: 10.1016/j.meegid.2017.09.008. Epub 2017 Sep 13.

PMID:
28919545
13.

Constitutive resistance to viral infection in human CD141+ dendritic cells.

Silvin A, Yu CI, Lahaye X, Imperatore F, Brault JB, Cardinaud S, Becker C, Kwan WH, Conrad C, Maurin M, Goudot C, Marques-Ladeira S, Wang Y, Pascual V, Anguiano E, Albrecht RA, Iannacone M, García-Sastre A, Goud B, Dalod M, Moris A, Merad M, Palucka AK, Manel N.

Sci Immunol. 2017 Jul 7;2(13). pii: eaai8071. doi: 10.1126/sciimmunol.aai8071.

14.

Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.

Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg MC, Picard C, Neven B, Fischer A, Amigorena S, Rieux-Laucat F, Manel N.

J Exp Med. 2017 Jun 5;214(6):1769-1785. doi: 10.1084/jem.20161674. Epub 2017 May 8.

15.

Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells.

Eichholz K, Bru T, Tran TT, Fernandes P, Welles H, Mennechet FJ, Manel N, Alves P, Perreau M, Kremer EJ.

PLoS Pathog. 2016 Sep 16;12(9):e1005871. doi: 10.1371/journal.ppat.1005871. eCollection 2016 Sep.

16.

Nuclear Envelope Protein SUN2 Promotes Cyclophilin-A-Dependent Steps of HIV Replication.

Lahaye X, Satoh T, Gentili M, Cerboni S, Silvin A, Conrad C, Ahmed-Belkacem A, Rodriguez EC, Guichou JF, Bosquet N, Piel M, Le Grand R, King MC, Pawlotsky JM, Manel N.

Cell Rep. 2016 Apr 26;15(4):879-892. doi: 10.1016/j.celrep.2016.03.074. Epub 2016 Apr 14.

17.

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death.

Raab M, Gentili M, de Belly H, Thiam HR, Vargas P, Jimenez AJ, Lautenschlaeger F, Voituriez R, Lennon-Duménil AM, Manel N, Piel M.

Science. 2016 Apr 15;352(6283):359-62. doi: 10.1126/science.aad7611. Epub 2016 Mar 24.

18.

cGAS-STING do it again: pivotal role in RNase H2 genetic disease.

Gentili M, Manel N.

EMBO J. 2016 Apr 15;35(8):796-7. doi: 10.15252/embj.201694226. Epub 2016 Mar 23. No abstract available.

19.

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing.

Decque A, Joffre O, Magalhaes JG, Cossec JC, Blecher-Gonen R, Lapaquette P, Silvin A, Manel N, Joubert PE, Seeler JS, Albert ML, Amit I, Amigorena S, Dejean A.

Nat Immunol. 2016 Feb;17(2):140-9. doi: 10.1038/ni.3342. Epub 2015 Dec 14.

PMID:
26657003
20.

Transmission of innate immune signaling by packaging of cGAMP in viral particles.

Gentili M, Kowal J, Tkach M, Satoh T, Lahaye X, Conrad C, Boyron M, Lombard B, Durand S, Kroemer G, Loew D, Dalod M, Théry C, Manel N.

Science. 2015 Sep 11;349(6253):1232-6. doi: 10.1126/science.aab3628. Epub 2015 Jul 30.

21.

Aicardi-Goutières syndrome and the type I interferonopathies.

Crow YJ, Manel N.

Nat Rev Immunol. 2015 Jul;15(7):429-40. doi: 10.1038/nri3850. Epub 2015 Jun 5. Review.

PMID:
26052098
22.

Viral and cellular mechanisms of the innate immune sensing of HIV.

Lahaye X, Manel N.

Curr Opin Virol. 2015 Apr;11:55-62. doi: 10.1016/j.coviro.2015.01.013. Epub 2015 Feb 17. Review.

PMID:
25697108
23.

Innate immune sensing of HIV infection.

Silvin A, Manel N.

Curr Opin Immunol. 2015 Feb;32:54-60. doi: 10.1016/j.coi.2014.12.003. Epub 2015 Jan 24. Review.

PMID:
25617674
24.

Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations.

Jeremiah N, Neven B, Gentili M, Callebaut I, Maschalidi S, Stolzenberg MC, Goudin N, Frémond ML, Nitschke P, Molina TJ, Blanche S, Picard C, Rice GI, Crow YJ, Manel N, Fischer A, Bader-Meunier B, Rieux-Laucat F.

J Clin Invest. 2014 Dec;124(12):5516-20. doi: 10.1172/JCI79100. Epub 2014 Nov 17.

25.

[HIV-2 reveals an antiviral mechanism of detection by innate immunity].

Lahaye X, Manel N.

Med Sci (Paris). 2014 Jun-Jul;30(6-7):610-3. doi: 10.1051/medsci/20143006004. Epub 2014 Jul 11. French. No abstract available.

26.

Combinatorial flexibility of cytokine function during human T helper cell differentiation.

Touzot M, Grandclaudon M, Cappuccio A, Satoh T, Martinez-Cingolani C, Servant N, Manel N, Soumelis V.

Nat Commun. 2014 May 28;5:3987. doi: 10.1038/ncomms4987.

PMID:
24865484
27.

The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells.

Lahaye X, Satoh T, Gentili M, Cerboni S, Conrad C, Hurbain I, El Marjou A, Lacabaratz C, Lelièvre JD, Manel N.

Immunity. 2013 Dec 12;39(6):1132-42. doi: 10.1016/j.immuni.2013.11.002. Epub 2013 Nov 21.

28.

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles.

Colombo M, Moita C, van Niel G, Kowal J, Vigneron J, Benaroch P, Manel N, Moita LF, Théry C, Raposo G.

J Cell Sci. 2013 Dec 15;126(Pt 24):5553-65. doi: 10.1242/jcs.128868. Epub 2013 Oct 8.

29.

Diversity of pathogen sensors in dendritic cells.

Cerboni S, Gentili M, Manel N.

Adv Immunol. 2013;120:211-37. doi: 10.1016/B978-0-12-417028-5.00008-9. Review.

PMID:
24070386
30.

Gene transduction in human monocyte-derived dendritic cells using lentiviral vectors.

Satoh T, Manel N.

Methods Mol Biol. 2013;960:401-409. doi: 10.1007/978-1-62703-218-6_30.

PMID:
23329503
31.

Interactions between HIV-1 and innate immunity in dendritic cells.

Silvin A, Manel N.

Adv Exp Med Biol. 2013;762:183-200. doi: 10.1007/978-1-4614-4433-6_7. Review.

PMID:
22975876
32.

Hiding in plain sight: how HIV evades innate immune responses.

Manel N, Littman DR.

Cell. 2011 Oct 14;147(2):271-4. doi: 10.1016/j.cell.2011.09.010. Review.

33.

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.

Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR.

Nature. 2011 Apr 28;472(7344):486-90. doi: 10.1038/nature09978. Epub 2011 Mar 27.

34.

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.

Manel N, Hogstad B, Wang Y, Levy DE, Unutmaz D, Littman DR.

Nature. 2010 Sep 9;467(7312):214-7. doi: 10.1038/nature09337. Erratum in: Nature. 2011 Feb 17;470(7334):424.

35.

[Induction of gut mucosal Th17 cells by segmented filamentous bacteria].

Ivanov II, Manel N.

Med Sci (Paris). 2010 Apr;26(4):352-5. doi: 10.1051/medsci/2010264352. French. No abstract available.

36.

Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection.

El Hed A, Khaitan A, Kozhaya L, Manel N, Daskalakis D, Borkowsky W, Valentine F, Littman DR, Unutmaz D.

J Infect Dis. 2010 Mar 15;201(6):843-54. doi: 10.1086/651021.

37.

Induction of intestinal Th17 cells by segmented filamentous bacteria.

Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, Wei D, Goldfarb KC, Santee CA, Lynch SV, Tanoue T, Imaoka A, Itoh K, Takeda K, Umesaki Y, Honda K, Littman DR.

Cell. 2009 Oct 30;139(3):485-98. doi: 10.1016/j.cell.2009.09.033.

38.

Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine.

Ivanov II, Frutos Rde L, Manel N, Yoshinaga K, Rifkin DB, Sartor RB, Finlay BB, Littman DR.

Cell Host Microbe. 2008 Oct 16;4(4):337-49. doi: 10.1016/j.chom.2008.09.009.

39.

Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection.

Srivastava S, Swanson SK, Manel N, Florens L, Washburn MP, Skowronski J.

PLoS Pathog. 2008 May 9;4(5):e1000059. doi: 10.1371/journal.ppat.1000059.

40.

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat.

Manel N, Unutmaz D, Littman DR.

Nat Immunol. 2008 Jun;9(6):641-9. doi: 10.1038/ni.1610. Epub 2008 May 4.

41.

[Red cell GLUT1 compensates for the lack of vitamin C synthesis in mammals].

Montel-Hagen A, Kinet S, Manel N, Mongellaz C, Prohaska R, Battini JL, Delaunay J, Sitbon M, Taylor N.

Med Sci (Paris). 2008 Apr;24(4):434-6. doi: 10.1051/medsci/2008244434. French. No abstract available.

42.

Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C.

Montel-Hagen A, Kinet S, Manel N, Mongellaz C, Prohaska R, Battini JL, Delaunay J, Sitbon M, Taylor N.

Cell. 2008 Mar 21;132(6):1039-48. doi: 10.1016/j.cell.2008.01.042.

43.

Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells.

Kinet S, Swainson L, Lavanya M, Mongellaz C, Montel-Hagen A, Craveiro M, Manel N, Battini JL, Sitbon M, Taylor N.

Retrovirology. 2007 May 15;4:31.

44.
45.

HTLV-1 tropism and envelope receptor.

Manel N, Battini JL, Taylor N, Sitbon M.

Oncogene. 2005 Sep 5;24(39):6016-25. Review.

PMID:
16155608
46.

Glucose transporter 1 expression identifies a population of cycling CD4+ CD8+ human thymocytes with high CXCR4-induced chemotaxis.

Swainson L, Kinet S, Manel N, Battini JL, Sitbon M, Taylor N.

Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12867-72. Epub 2005 Aug 26.

47.

Human T cell leukemia virus envelope binding and virus entry are mediated by distinct domains of the glucose transporter GLUT1.

Manel N, Battini JL, Sitbon M.

J Biol Chem. 2005 Aug 12;280(32):29025-9. Epub 2005 Jun 13.

48.

HTLV-1 and -2 envelope SU subdomains and critical determinants in receptor binding.

Kim FJ, Manel N, Garrido EN, Valle C, Sitbon M, Battini JL.

Retrovirology. 2004 Dec 2;1:41.

49.

[Envelope capture by retroviruses].

Kim FJ, Manel N, Battini JL, Sitbon M.

Med Sci (Paris). 2004 Oct;20(10):876-81. Review. French.

50.

HTLV envelopes and their receptor GLUT1, the ubiquitous glucose transporter: a new vision on HTLV infection?

Manel N, Taylor N, Kinet S, Kim FJ, Swainson L, Lavanya M, Battini JL, Sitbon M.

Front Biosci. 2004 Sep 1;9:3218-41. Review.

PMID:
15353351

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