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Items: 14


The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer.

Uribe DJ, Mandell EK, Watson A, Martinez JD, Leighton JA, Ghosh S, Rothlin CV.

PLoS One. 2017 Jul 20;12(7):e0179979. doi: 10.1371/journal.pone.0179979. eCollection 2017.


Endosomal regulation of contact inhibition through the AMOT:YAP pathway.

Cox CM, Mandell EK, Stewart L, Lu R, Johnson DL, McCarter SD, Tavares A, Runyan R, Ghosh S, Wilson JM.

Mol Biol Cell. 2015 Jul 15;26(14):2673-84. doi: 10.1091/mbc.E15-04-0224. Epub 2015 May 20.


PKCι interacts with Rab14 and modulates epithelial barrier function through regulation of claudin-2 levels.

Lu R, Dalgalan D, Mandell EK, Parker SS, Ghosh S, Wilson JM.

Mol Biol Cell. 2015 Apr 15;26(8):1523-31. doi: 10.1091/mbc.E14-12-1613. Epub 2015 Feb 18.


Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Kusne Y, Carrera-Silva EA, Perry AS, Rushing EJ, Mandell EK, Dietrich JD, Errasti AE, Gibbs D, Berens ME, Loftus JC, Hulme C, Yang W, Lu Z, Aldape K, Sanai N, Rothlin CV, Ghosh S.

Sci Signal. 2014 Aug 12;7(338):ra75. doi: 10.1126/scisignal.2005196.


Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity.

Melemedjian OK, Tillu DV, Moy JK, Asiedu MN, Mandell EK, Ghosh S, Dussor G, Price TJ.

Mol Pain. 2014 Jul 4;10:45. doi: 10.1186/1744-8069-10-45.


Competing molecular interactions of aPKC isoforms regulate neuronal polarity.

Parker SS, Mandell EK, Hapak SM, Maskaykina IY, Kusne Y, Kim JY, Moy JK, St John PA, Wilson JM, Gothard KM, Price TJ, Ghosh S.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14450-5. doi: 10.1073/pnas.1301588110. Epub 2013 Aug 12.


BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state.

Melemedjian OK, Tillu DV, Asiedu MN, Mandell EK, Moy JK, Blute VM, Taylor CJ, Ghosh S, Price TJ.

Mol Pain. 2013 Mar 20;9:12. doi: 10.1186/1744-8069-9-12.


Dissecting protein function: an efficient protocol for identifying separation-of-function mutations that encode structurally stable proteins.

Lubin JW, Rao T, Mandell EK, Wuttke DS, Lundblad V.

Genetics. 2013 Mar;193(3):715-25. doi: 10.1534/genetics.112.147801. Epub 2013 Jan 10.


Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain.

King T, Qu C, Okun A, Melemedjian OK, Mandell EK, Maskaykina IY, Navratilova E, Dussor GO, Ghosh S, Price TJ, Porreca F.

Pain. 2012 Jun;153(6):1263-73. doi: 10.1016/j.pain.2012.03.006. Epub 2012 Apr 4.


Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain.

Mandell EK, Gelinas AD, Wuttke DS, Lundblad V.

Biochemistry. 2011 Jul 26;50(29):6289-91. doi: 10.1021/bi2005448. Epub 2011 Jun 29.


Structure prediction-driven genetics in Saccharomyces cerevisiae identifies an interface between the t-RPA proteins Stn1 and Ten1.

Paschini M, Mandell EK, Lundblad V.

Genetics. 2010 May;185(1):11-21. doi: 10.1534/genetics.109.111922. Epub 2010 Feb 15.


Investigating the role of the Est3 protein in yeast telomere replication.

Lee J, Mandell EK, Rao T, Wuttke DS, Lundblad V.

Nucleic Acids Res. 2010 Apr;38(7):2279-90. doi: 10.1093/nar/gkp1173. Epub 2010 Jan 4.


The Est3 protein associates with yeast telomerase through an OB-fold domain.

Lee J, Mandell EK, Tucey TM, Morris DK, Lundblad V.

Nat Struct Mol Biol. 2008 Sep;15(9):990-7.


RPA-like proteins mediate yeast telomere function.

Gao H, Cervantes RB, Mandell EK, Otero JH, Lundblad V.

Nat Struct Mol Biol. 2007 Mar;14(3):208-14. Epub 2007 Feb 11.


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