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Items: 1 to 50 of 66

1.

Double traumatic diaphragmatic injury: A case report.

Iadicola D, Branca M, Lupo M, Grutta EM, Mandalà S, Cocorullo G, Mirabella A.

Int J Surg Case Rep. 2019;61:82-85. doi: 10.1016/j.ijscr.2019.07.030. Epub 2019 Jul 19.

2.

ECG Parameters for Malignant Ventricular Arrhythmias: A Comprehensive Review.

Mandala S, Di TC.

J Med Biol Eng. 2017;37(4):441-453. doi: 10.1007/s40846-017-0281-x. Epub 2017 Jun 28. Review.

3.

2017 update of the WSES guidelines for emergency repair of complicated abdominal wall hernias.

Birindelli A, Sartelli M, Di Saverio S, Coccolini F, Ansaloni L, van Ramshorst GH, Campanelli G, Khokha V, Moore EE, Peitzman A, Velmahos G, Moore FA, Leppaniemi A, Burlew CC, Biffl WL, Koike K, Kluger Y, Fraga GP, Ordonez CA, Novello M, Agresta F, Sakakushev B, Gerych I, Wani I, Kelly MD, Gomes CA, Faro MP Jr, Tarasconi A, Demetrashvili Z, Lee JG, Vettoretto N, Guercioni G, Persiani R, Tranà C, Cui Y, Kok KYY, Ghnnam WM, Abbas AE, Sato N, Marwah S, Rangarajan M, Ben-Ishay O, Adesunkanmi ARK, Lohse HAS, Kenig J, Mandalà S, Coimbra R, Bhangu A, Suggett N, Biondi A, Portolani N, Baiocchi G, Kirkpatrick AW, Scibé R, Sugrue M, Chiara O, Catena F.

World J Emerg Surg. 2017 Aug 7;12:37. doi: 10.1186/s13017-017-0149-y. eCollection 2017. Review.

4.

Current status of laparoscopy for acute abdomen in Italy: a critical appraisal of 2012 clinical guidelines from two consecutive nationwide surveys with analysis of 271,323 cases over 5 years.

Agresta F, Campanile FC, Podda M, Cillara N, Pernazza G, Giaccaglia V, Ciccoritti L, Ioia G, Mandalà S, La Barbera C, Birindelli A, Sartelli M, Di Saverio S; Joined Italian Surgical Societies Working Group.

Surg Endosc. 2017 Apr;31(4):1785-1795. doi: 10.1007/s00464-016-5175-4. Epub 2016 Aug 29.

PMID:
27572068
5.

Current management of intestinal bowel disease: the role of surgery.

Solina G, Mandalà S, La Barbera C, Mandalà V.

Updates Surg. 2016 Mar;68(1):13-23. doi: 10.1007/s13304-016-0361-4. Epub 2016 Apr 11. Review.

PMID:
27067590
6.

Laparoscopic treatment of incisional and primary ventral hernia in morbidly obese patients with a BMI over 35.

Marx L, Raharimanantsoa M, Mandala S, D'Urso A, Vix M, Mutter D.

Surg Endosc. 2014 Dec;28(12):3310-4. doi: 10.1007/s00464-014-3607-6. Epub 2014 Jul 10.

PMID:
25007972
7.

Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase.

Liu P, Hamill TG, Chioda M, Chobanian H, Fung S, Guo Y, Chang L, Bakshi R, Hong Q, Dellureficio J, Lin LS, Abbadie C, Alexander J, Jin H, Mandala S, Shiao LL, Li W, Sanabria S, Williams D, Zeng Z, Hajdu R, Jochnowitz N, Rosenbach M, Karanam B, Madeira M, Salituro G, Powell J, Xu L, Terebetski JL, Leone JF, Miller P, Cook J, Holahan M, Joshi A, O'Malley S, Purcell M, Posavec D, Chen TB, Riffel K, Williams M, Hargreaves R, Sullivan KA, Nargund RP, DeVita RJ.

ACS Med Chem Lett. 2013 Apr 20;4(6):509-13. doi: 10.1021/ml4000996. eCollection 2013 Jun 13.

8.

Cross-infection of solid organ transplant recipients by a multidrug-resistant Klebsiella pneumoniae isolate producing the OXA-48 carbapenemase, likely derived from a multiorgan donor.

Giani T, Conte V, Mandalà S, D'Andrea MM, Luzzaro F, Conaldi PG, Grossi P, Rossolini GM.

J Clin Microbiol. 2014 Jul;52(7):2702-5. doi: 10.1128/JCM.00511-14. Epub 2014 Apr 23.

9.

WSES guidelines for emergency repair of complicated abdominal wall hernias.

Sartelli M, Coccolini F, van Ramshorst GH, Campanelli G, Mandalà V, Ansaloni L, Moore EE, Peitzman A, Velmahos G, Moore FA, Leppaniemi A, Burlew CC, Biffl W, Koike K, Kluger Y, Fraga GP, Ordonez CA, Di Saverio S, Agresta F, Sakakushev B, Gerych I, Wani I, Kelly MD, Gomes CA, Faro MP Jr, Taviloglu K, Demetrashvili Z, Lee JG, Vettoretto N, Guercioni G, Tranà C, Cui Y, Kok KY, Ghnnam WM, Abbas Ael-S, Sato N, Marwah S, Rangarajan M, Ben-Ishay O, Adesunkanmi AR, Segovia Lohse HA, Kenig J, Mandalà S, Patrizi A, Scibé R, Catena F.

World J Emerg Surg. 2013 Dec 1;8(1):50. doi: 10.1186/1749-7922-8-50.

10.

Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group.

Di Saverio S, Coccolini F, Galati M, Smerieri N, Biffl WL, Ansaloni L, Tugnoli G, Velmahos GC, Sartelli M, Bendinelli C, Fraga GP, Kelly MD, Moore FA, Mandalà V, Mandalà S, Masetti M, Jovine E, Pinna AD, Peitzman AB, Leppaniemi A, Sugarbaker PH, Goor HV, Moore EE, Jeekel J, Catena F.

World J Emerg Surg. 2013 Oct 10;8(1):42. doi: 10.1186/1749-7922-8-42.

11.

Detecting alternative graph clusterings.

Mandala S, Kumara S, Yao T.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Jul;86(1 Pt 2):016111. Epub 2012 Jul 23.

PMID:
23005495
12.

1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.

Vachal P, Miao S, Pierce JM, Guiadeen D, Colandrea VJ, Wyvratt MJ, Salowe SP, Sonatore LM, Milligan JA, Hajdu R, Gollapudi A, Keohane CA, Lingham RB, Mandala SM, DeMartino JA, Tong X, Wolff M, Steinhuebel D, Kieczykowski GR, Fleitz FJ, Chapman K, Athanasopoulos J, Adam G, Akyuz CD, Jena DK, Lusen JW, Meng J, Stein BD, Xia L, Sherer EC, Hale JJ.

J Med Chem. 2012 Apr 12;55(7):2945-59. doi: 10.1021/jm201542d. Epub 2012 Feb 27.

PMID:
22364528
13.

Bologna Guidelines for Diagnosis and Management of Adhesive Small Bowel Obstruction (ASBO): 2010 Evidence-Based Guidelines of the World Society of Emergency Surgery.

Catena F, Di Saverio S, Kelly MD, Biffl WL, Ansaloni L, Mandalà V, Velmahos GC, Sartelli M, Tugnoli G, Lupo M, Mandalà S, Pinna AD, Sugarbaker PH, Van Goor H, Moore EE, Jeekel J.

World J Emerg Surg. 2011 Jan 21;6:5. doi: 10.1186/1749-7922-6-5.

14.

The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase.

Petersen LN, Marineo S, Mandalà S, Davids F, Sewell BT, Ingle RA.

Plant Physiol. 2010 Mar;152(3):1186-96. doi: 10.1104/pp.109.150805. Epub 2009 Dec 18.

15.

Gastrointestinal stromal tumour of the rectum: report of a case and review of literature.

Grassi N, Cipolla C, Torcivia A, Mandala S, Graceffa G, Bottino A, Latteri F.

World J Gastroenterol. 2008 Feb 28;14(8):1302-4.

16.

Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina.

Skoura A, Sanchez T, Claffey K, Mandala SM, Proia RL, Hla T.

J Clin Invest. 2007 Sep;117(9):2506-16.

17.

Identification of Leu276 of the S1P1 receptor and Phe263 of the S1P3 receptor in interaction with receptor specific agonists by molecular modeling, site-directed mutagenesis, and affinity studies.

Deng Q, Clemas JA, Chrebet G, Fischer P, Hale JJ, Li Z, Mills SG, Bergstrom J, Mandala S, Mosley R, Parent SA.

Mol Pharmacol. 2007 Mar;71(3):724-35. Epub 2006 Dec 14.

PMID:
17170199
18.

SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties.

Yan L, Huo P, Hale JJ, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Mandala SM.

Bioorg Med Chem Lett. 2007 Feb 1;17(3):828-31. Epub 2006 Oct 25.

PMID:
17092714
19.

Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes.

Yan L, Huo P, Doherty G, Toth L, Hale JJ, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Quackenbush E, Wickham A, Mandala SM.

Bioorg Med Chem Lett. 2006 Jul 15;16(14):3679-83. Epub 2006 May 11.

PMID:
16697189
20.

Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.

Vachal P, Toth LM, Hale JJ, Yan L, Mills SG, Chrebet GL, Koehane CA, Hajdu R, Milligan JA, Rosenbach MJ, Mandala S.

Bioorg Med Chem Lett. 2006 Jul 15;16(14):3684-7. Epub 2006 May 6.

PMID:
16682185
21.

2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors.

Yan L, Budhu R, Huo P, Lynch CL, Hale JJ, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Mandala SM.

Bioorg Med Chem Lett. 2006 Jul 1;16(13):3564-8. Epub 2006 Apr 18.

PMID:
16621543
22.

2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists.

Colandrea VJ, Legiec IE, Huo P, Yan L, Hale JJ, Mills SG, Bergstrom J, Card D, Chebret G, Hajdu R, Keohane CA, Milligan JA, Rosenbach MJ, Shei GJ, Mandala SM.

Bioorg Med Chem Lett. 2006 Jun 1;16(11):2905-8. Epub 2006 Mar 31.

PMID:
16580205
23.

Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes.

Singer II, Tian M, Wickham LA, Lin J, Matheravidathu SS, Forrest MJ, Mandala S, Quackenbush EJ.

J Immunol. 2005 Dec 1;175(11):7151-61.

24.

Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3.

Li Z, Chen W, Hale JJ, Lynch CL, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Parent SA, Bergstrom J, Card D, Forrest M, Quackenbush EJ, Wickham LA, Vargas H, Evans RM, Rosen H, Mandala S.

J Med Chem. 2005 Oct 6;48(20):6169-73.

PMID:
16190743
25.

Sphingosine 1-phosphate receptor agonist FTY720-phosphate causes marginal zone B cell displacement.

Vora KA, Nichols E, Porter G, Cui Y, Keohane CA, Hajdu R, Hale J, Neway W, Zaller D, Mandala S.

J Leukoc Biol. 2005 Aug;78(2):471-80. Epub 2005 May 13.

PMID:
15894589
26.

The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches.

Halin C, Scimone ML, Bonasio R, Gauguet JM, Mempel TR, Quackenbush E, Proia RL, Mandala S, von Andrian UH.

Blood. 2005 Aug 15;106(4):1314-22. Epub 2005 May 3.

27.

A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.

Hale JJ, Lynch CL, Neway W, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Parent SA, Chrebet G, Bergstrom J, Card D, Ferrer M, Hodder P, Strulovici B, Rosen H, Mandala S.

J Med Chem. 2004 Dec 30;47(27):6662-5.

PMID:
15615513
28.

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

Allende ML, Sasaki T, Kawai H, Olivera A, Mi Y, van Echten-Deckert G, Hajdu R, Rosenbach M, Keohane CA, Mandala S, Spiegel S, Proia RL.

J Biol Chem. 2004 Dec 10;279(50):52487-92. Epub 2004 Sep 30.

29.

Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors.

Yan L, Hale JJ, Lynch CL, Budhu R, Gentry A, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Rosen H, Mandala SM.

Bioorg Med Chem Lett. 2004 Oct 4;14(19):4861-6.

PMID:
15341940
30.

Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720.

Hale JJ, Yan L, Neway WE, Hajdu R, Bergstrom JD, Milligan JA, Shei GJ, Chrebet GL, Thornton RA, Card D, Rosenbach M, HughRosen, Mandala S.

Bioorg Med Chem. 2004 Sep 15;12(18):4803-7.

PMID:
15336258
31.

Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice.

Webb M, Tham CS, Lin FF, Lariosa-Willingham K, Yu N, Hale J, Mandala S, Chun J, Rao TS.

J Neuroimmunol. 2004 Aug;153(1-2):108-21.

PMID:
15265669
32.

Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists.

Hale JJ, Doherty G, Toth L, Mills SG, Hajdu R, Keohane CA, Rosenbach M, Milligan J, Shei GJ, Chrebet G, Bergstrom J, Card D, Forrest M, Sun SY, West S, Xie H, Nomura N, Rosen H, Mandala S.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3501-5.

PMID:
15177461
33.

The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists.

Hale JJ, Doherty G, Toth L, Li Z, Mills SG, Hajdu R, Ann Keohane C, Rosenbach M, Milligan J, Shei GJ, Chrebet G, Bergstrom J, Card D, Rosen H, Mandala S.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3495-9.

PMID:
15177460
34.

Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720.

Hale JJ, Neway W, Mills SG, Hajdu R, Ann Keohane C, Rosenbach M, Milligan J, Shei GJ, Chrebet G, Bergstrom J, Card D, Koo GC, Koprak SL, Jackson JJ, Rosen H, Mandala S.

Bioorg Med Chem Lett. 2004 Jun 21;14(12):3351-5.

PMID:
15149705
35.

A fully automated [35S]GTPgammaS scintillation proximity assay for the high-throughput screening of Gi-linked G protein-coupled receptors.

Ferrer M, Kolodin GD, Zuck P, Peltier R, Berry K, Mandala SM, Rosen H, Ota H, Ozaki S, Inglese J, Strulovici B.

Assay Drug Dev Technol. 2003 Apr;1(2):261-73.

PMID:
15090191
36.

Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes.

Forrest M, Sun SY, Hajdu R, Bergstrom J, Card D, Doherty G, Hale J, Keohane C, Meyers C, Milligan J, Mills S, Nomura N, Rosen H, Rosenbach M, Shei GJ, Singer II, Tian M, West S, White V, Xie J, Proia RL, Mandala S.

J Pharmacol Exp Ther. 2004 May;309(2):758-68. Epub 2004 Jan 27.

PMID:
14747617
37.

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration.

Allende ML, Dreier JL, Mandala S, Proia RL.

J Biol Chem. 2004 Apr 9;279(15):15396-401. Epub 2004 Jan 19.

38.

Phytosphingosine 1-phosphate: a high affinity ligand for the S1P(4)/Edg-6 receptor.

Candelore MR, Wright MJ, Tota LM, Milligan J, Shei GJ, Bergstrom JD, Mandala SM.

Biochem Biophys Res Commun. 2002 Sep 27;297(3):600-6.

PMID:
12270137
39.

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.

Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, Rosenbach M, Hale J, Lynch CL, Rupprecht K, Parsons W, Rosen H.

Science. 2002 Apr 12;296(5566):346-9. Epub 2002 Mar 28.

40.

Characterization of murine sphingosine-1-phosphate phosphohydrolase.

Le Stunff H, Peterson C, Thornton R, Milstien S, Mandala SM, Spiegel S.

J Biol Chem. 2002 Mar 15;277(11):8920-7. Epub 2001 Dec 26.

41.

Sphingosine-1-phosphate phosphatases.

Mandala SM.

Prostaglandins Other Lipid Mediat. 2001 Apr;64(1-4):143-56. Review.

PMID:
11324704
42.

The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae.

Baudry K, Swain E, Rahier A, Germann M, Batta A, Rondet S, Mandala S, Henry K, Tint GS, Edlind T, Kurtz M, Nickels JT Jr.

J Biol Chem. 2001 Apr 20;276(16):12702-11. Epub 2001 Jan 18.

43.

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death.

Mandala SM, Thornton R, Galve-Roperh I, Poulton S, Peterson C, Olivera A, Bergstrom J, Kurtz MB, Spiegel S.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7859-64.

44.

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8.

Im DS, Heise CE, Ancellin N, O'Dowd BF, Shei GJ, Heavens RP, Rigby MR, Hla T, Mandala S, McAllister G, George SR, Lynch KR.

J Biol Chem. 2000 May 12;275(19):14281-6.

45.
46.

Inhibition of fungal sphingolipid biosynthesis by rustmicin, galbonolide B and their new 21-hydroxy analogs.

Harris GH, Shafiee A, Cabello MA, Curotto JE, Genilloud O, Göklen KE, Kurtz MB, Rosenbach M, Salmon PM, Thornton RA, Zink DL, Mandala SM.

J Antibiot (Tokyo). 1998 Sep;51(9):837-44.

47.

Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase.

Mandala SM, Thornton RA, Milligan J, Rosenbach M, Garcia-Calvo M, Bull HG, Harris G, Abruzzo GK, Flattery AM, Gill CJ, Bartizal K, Dreikorn S, Kurtz MB.

J Biol Chem. 1998 Jun 12;273(24):14942-9.

48.

Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

Mandala SM, Thornton R, Tu Z, Kurtz MB, Nickels J, Broach J, Menzeleev R, Spiegel S.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):150-5.

49.

Khafrefungin, a novel inhibitor of sphingolipid synthesis.

Mandala SM, Thornton RA, Rosenbach M, Milligan J, Garcia-Calvo M, Bull HG, Kurtz MB.

J Biol Chem. 1997 Dec 19;272(51):32709-14.

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