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Items: 5


ATM directs DNA damage responses and proteostasis via genetically separable pathways.

Lee JH, Mand MR, Kao CH, Zhou Y, Ryu SW, Richards AL, Coon JJ, Paull TT.

Sci Signal. 2018 Jan 9;11(512). pii: eaan5598. doi: 10.1126/scisignal.aan5598.


Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.

Lee JH, Mand MR, Deshpande RA, Kinoshita E, Yang SH, Wyman C, Paull TT.

J Biol Chem. 2013 May 3;288(18):12840-51. doi: 10.1074/jbc.M113.460378. Epub 2013 Mar 22.


Cell treatment and lysis in 96-well filter-bottom plates for screening Bcr-Abl activity and inhibition in whole-cell extracts.

Mand MR, Wu D, Veach DR, Kron SJ.

J Biomol Screen. 2010 Apr;15(4):434-40. doi: 10.1177/1087057110363307. Epub 2010 Mar 17.


A rationally designed histone deacetylase inhibitor with distinct antitumor activity against ovarian cancer.

Yang YT, Balch C, Kulp SK, Mand MR, Nephew KP, Chen CS.

Neoplasia. 2009 Jun;11(6):552-63, 3 p following 563.


A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates.

Wu D, Mand MR, Veach DR, Parker LL, Clarkson B, Kron SJ.

Anal Biochem. 2008 Apr 1;375(1):18-26. doi: 10.1016/j.ab.2007.12.023. Epub 2007 Dec 25.

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