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Items: 1 to 50 of 205

1.

5-(Carbamoylmethylene)-oxazolidin-2-ones as a Promising Class of Heterocycles Inducing Apoptosis Triggered by Increased ROS Levels and Mitochondrial Dysfunction in Breast and Cervical Cancer.

Armentano B, Curcio R, Brindisi M, Mancuso R, Rago V, Ziccarelli I, Frattaruolo L, Fiorillo M, Dolce V, Gabriele B, Cappello AR.

Biomedicines. 2020 Feb 18;8(2). pii: E35. doi: 10.3390/biomedicines8020035.

2.

Combined intramuscular and intraspinal transplant of bone marrow cells improves neuromuscular function in the SOD1G93A mice.

Martínez-Muriana A, Pastor D, Mancuso R, Rando A, Osta R, Martínez S, López-Vales R, Navarro X.

Stem Cell Res Ther. 2020 Feb 7;11(1):53. doi: 10.1186/s13287-020-1573-6.

3.

Site-Selective Double and Tetracyclization Routes to Fused Polyheterocyclic Structures by Pd-Catalyzed Carbonylation Reactions.

Pancrazzi F, Sarti N, Mazzeo PP, Bacchi A, Carfagna C, Mancuso R, Gabriele B, Costa M, Stirling A, Della Ca' N.

Org Lett. 2020 Feb 21;22(4):1569-1574. doi: 10.1021/acs.orglett.0c00171. Epub 2020 Feb 3.

PMID:
32011899
4.

Anti-αLβ2 antibodies reveal novel endocytotic cross-modulatory functionality.

Mancuso RV, Casper J, Schmidt AG, Krähenbühl S, Weitz-Schmidt G.

Br J Pharmacol. 2020 Jan 27. doi: 10.1111/bph.14996. [Epub ahead of print]

PMID:
31985813
5.

Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology.

Sierksma A, Lu A, Mancuso R, Fattorelli N, Thrupp N, Salta E, Zoco J, Blum D, Buée L, De Strooper B, Fiers M.

EMBO Mol Med. 2020 Mar 6;12(3):e10606. doi: 10.15252/emmm.201910606. Epub 2020 Jan 17.

6.

Microwave-Assisted Synthesis of Sulfurated Heterocycles with Herbicidal Activity: Reaction of 2-Alkynylbenzoic Acids with Lawesson's Reagent.

Giofrè SV, Mancuso R, Araniti F, Romeo R, Iannazzo D, Abenavoli MR, Gabriele B.

Chempluschem. 2019 Jul;84(7):942-950. doi: 10.1002/cplu.201900316.

PMID:
31943976
7.

Stem-cell-derived human microglia transplanted in mouse brain to study human disease.

Mancuso R, Van Den Daele J, Fattorelli N, Wolfs L, Balusu S, Burton O, Liston A, Sierksma A, Fourne Y, Poovathingal S, Arranz-Mendiguren A, Sala Frigerio C, Claes C, Serneels L, Theys T, Perry VH, Verfaillie C, Fiers M, De Strooper B.

Nat Neurosci. 2019 Dec;22(12):2111-2116. doi: 10.1038/s41593-019-0525-x. Epub 2019 Oct 28.

PMID:
31659342
8.

Candida albicans cell wall integrity transcription factors regulate polymicrobial biofilm formation with Streptococcus gordonii.

Chinnici J, Yerke L, Tsou C, Busarajan S, Mancuso R, Sadhak ND, Kim J, Maddi A.

PeerJ. 2019 Oct 11;7:e7870. doi: 10.7717/peerj.7870. eCollection 2019.

9.

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.

Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, Mudher A, Vicente-Rodriguez M, Parker CA, Simmons C, Cash D, Richardson J; NIMA Consortium , Jones DNC, Lovestone S, Gómez-Nicola D, Perry VH.

Brain. 2019 Oct 1;142(10):3243-3264. doi: 10.1093/brain/awz241.

10.

Herpes simplex virus-1 (HSV-1) infection induces a potent but ineffective IFN-λ production in immune cells of AD and PD patients.

La Rosa F, Agostini S, Bianchi A, Nemni R, Piancone F, Marventano I, Mancuso R, Saresella M, Clerici M.

J Transl Med. 2019 Aug 27;17(1):286. doi: 10.1186/s12967-019-2034-9.

11.

Herpes simplex virus type 1 and Alzheimer's disease: link and potential impact on treatment.

Mancuso R, Sicurella M, Agostini S, Marconi P, Clerici M.

Expert Rev Anti Infect Ther. 2019 Sep;17(9):715-731. doi: 10.1080/14787210.2019.1656064. Epub 2019 Aug 23. Review.

PMID:
31414935
12.

Immunoglobulin Genes and Immunity to HSV1 in Alzheimer's Disease.

Pandey JP, Kothera RT, Liu S, Costa AS, Mancuso R, Agostini S.

J Alzheimers Dis. 2019;70(3):917-924. doi: 10.3233/JAD-190265.

PMID:
31306125
13.

The PILRA G78R Variant Correlates with Higher HSV-1-Specific IgG Titers in Alzheimer's Disease.

Agostini S, Costa AS, Mancuso R, Guerini FR, Nemni R, Clerici M.

Cell Mol Neurobiol. 2019 Nov;39(8):1217-1221. doi: 10.1007/s10571-019-00712-5. Epub 2019 Jul 11.

PMID:
31297637
14.

Circulatory miR-223-3p Discriminates Between Parkinson's and Alzheimer's Patients.

Mancuso R, Agostini S, Hernis A, Zanzottera M, Bianchi A, Clerici M.

Sci Rep. 2019 Jun 28;9(1):9393. doi: 10.1038/s41598-019-45687-x.

15.

Benzofuran-2-acetic esters as a new class of natural-like herbicides.

Araniti F, Mancuso R, Lupini A, Sunseri F, Abenavoli MR, Gabriele B.

Pest Manag Sci. 2020 Jan;76(1):395-404. doi: 10.1002/ps.5528. Epub 2019 Jul 24.

PMID:
31228323
16.

New Polymeric Films with Antibacterial Activity Obtained by UV-induced Copolymerization of Acryloyloxyalkyltriethylammonium Salts with 2-Hydroethyl Methacrylate.

Galiano F, Mancuso R, Guzzo MG, Lucente F, Gukelberger E, Losso MA, Figoli A, Hoinkis J, Gabriele B.

Int J Mol Sci. 2019 May 31;20(11). pii: E2696. doi: 10.3390/ijms20112696.

17.

Catalytic Carbonylative Double Cyclization of 2-(3-Hydroxy-1-yn-1-yl)phenols in Ionic Liquids Leading to Furobenzofuranone Derivatives.

Mancuso R, Miliè R, Palumbo Piccionello A, Olivieri D, Della Ca' N, Carfagna C, Gabriele B.

J Org Chem. 2019 Jun 7;84(11):7303-7311. doi: 10.1021/acs.joc.9b00952. Epub 2019 May 29.

PMID:
31117578
18.

The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.

Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B.

Cell Rep. 2019 Apr 23;27(4):1293-1306.e6. doi: 10.1016/j.celrep.2019.03.099.

19.

Serum miRNAs Expression and SNAP-25 Genotype in Alzheimer's Disease.

Agostini S, Mancuso R, Liuzzo G, Bolognesi E, Costa AS, Bianchi A, Clerici M.

Front Aging Neurosci. 2019 Mar 11;11:52. doi: 10.3389/fnagi.2019.00052. eCollection 2019.

20.

Synthesis of Imidazolidin-2-ones and Imidazol-2-ones via Base-Catalyzed Intramolecular Hydroamidation of Propargylic Ureas under Ambient Conditions.

Casnati A, Perrone A, Mazzeo PP, Bacchi A, Mancuso R, Gabriele B, Maggi R, Maestri G, Motti E, Stirling A, Ca' ND.

J Org Chem. 2019 Mar 15;84(6):3477-3490. doi: 10.1021/acs.joc.9b00064. Epub 2019 Feb 28.

PMID:
30788963
21.

A Smart Nanovector for Cancer Targeted Drug Delivery Based on Graphene Quantum Dots.

Iannazzo D, Pistone A, Celesti C, Triolo C, Patané S, Giofré SV, Romeo R, Ziccarelli I, Mancuso R, Gabriele B, Visalli G, Facciolà A, Di Pietro A.

Nanomaterials (Basel). 2019 Feb 18;9(2). pii: E282. doi: 10.3390/nano9020282.

22.

Catalytic Double Cyclization Process for Antitumor Agents against Breast Cancer Cell Lines.

Mancuso R, Ziccarelli I, Chimento A, Marino N, Della Ca' N, Sirianni R, Pezzi V, Gabriele B.

iScience. 2018 May 25;3:279-288. doi: 10.1016/j.isci.2018.04.022. Epub 2018 May 3.

23.

Functions of Candida albicans cell wall glycosidases Dfg5p and Dcw1p in biofilm formation and HOG MAPK pathway.

Mancuso R, Chinnici J, Tsou C, Busarajan S, Munnangi R, Maddi A.

PeerJ. 2018 Sep 28;6:e5685. doi: 10.7717/peerj.5685. eCollection 2018.

24.

Particular CSF sphingolipid patterns identify iNPH and AD patients.

Torretta E, Arosio B, Barbacini P, Casati M, Capitanio D, Mancuso R, Mari D, Cesari M, Clerici M, Gelfi C.

Sci Rep. 2018 Sep 11;8(1):13639. doi: 10.1038/s41598-018-31756-0.

25.

A simple and universal enzyme-free approach for the detection of multiple microRNAs using a single nanostructured enhancer of surface plasmon resonance imaging.

Sguassero A, Artiga Á, Morasso C, Jimenez RR, Rapún RM, Mancuso R, Agostini S, Hernis A, Abols A, Linē A, Gualerzi A, Picciolini S, Bedoni M, Rovaris M, Gramatica F, de la Fuente JM, Vanna R.

Anal Bioanal Chem. 2019 Mar;411(9):1873-1885. doi: 10.1007/s00216-018-1331-0. Epub 2018 Aug 28.

PMID:
30155701
26.

PD-1 deficiency is not sufficient to induce myeloid mobilization to the brain or alter the inflammatory profile during chronic neurodegeneration.

Obst J, Mancuso R, Simon E, Gomez-Nicola D.

Brain Behav Immun. 2018 Oct;73:708-716. doi: 10.1016/j.bbi.2018.08.006. Epub 2018 Aug 4.

27.

Poor sleep quality increases symptoms of depression and anxiety in postpartum women.

Okun ML, Mancuso RA, Hobel CJ, Schetter CD, Coussons-Read M.

J Behav Med. 2018 Oct;41(5):703-710. doi: 10.1007/s10865-018-9950-7. Epub 2018 Jul 20.

28.

Divergent Syntheses of ( Z)-3-Alkylideneisobenzofuran-1(3 H)-ones and 1 H-Isochromen-1-ones by Copper-Catalyzed Cycloisomerization of 2-Alkynylbenzoic Acids in Ionic Liquids.

Mancuso R, Pomelli CS, Chiappetta P, Gioia KF, Maner A, Marino N, Veltri L, Chiappe C, Gabriele B.

J Org Chem. 2018 Jun 15;83(12):6673-6680. doi: 10.1021/acs.joc.8b00923. Epub 2018 Jun 4.

PMID:
29792429
29.

HLA alleles modulate EBV viral load in multiple sclerosis.

Agostini S, Mancuso R, Guerini FR, D'Alfonso S, Agliardi C, Hernis A, Zanzottera M, Barizzone N, Leone MA, Caputo D, Rovaris M, Clerici M.

J Transl Med. 2018 Mar 27;16(1):80. doi: 10.1186/s12967-018-1450-6.

30.

HSV-1-Specific IgG Subclasses Distribution and Serum Neutralizing Activity in Alzheimer's Disease and in Mild Cognitive Impairment.

Agostini S, Mancuso R, Hernis A, Costa AS, Nemni R, Clerici M.

J Alzheimers Dis. 2018;63(1):131-138. doi: 10.3233/JAD-170966.

PMID:
29578484
31.

An Unprecedented Pd-Catalyzed Carbonylative Route to Fused Furo[3,4-b]indol-1-ones.

Acerbi A, Carfagna C, Costa M, Mancuso R, Gabriele B, Della Ca' N.

Chemistry. 2018 Apr 3;24(19):4835-4840. doi: 10.1002/chem.201706067. Epub 2018 Mar 5.

PMID:
29390167
32.

Novel low-fouling membranes from lab to pilot application in textile wastewater treatment.

Galiano F, Friha I, Deowan SA, Hoinkis J, Xiaoyun Y, Johnson D, Mancuso R, Hilal N, Gabriele B, Sayadi S, Figoli A.

J Colloid Interface Sci. 2018 Apr 1;515:208-220. doi: 10.1016/j.jcis.2018.01.009. Epub 2018 Jan 5.

PMID:
29335187
33.

Receiving Spiritual Care: Experiences of Dying and Grieving Individuals.

Bonavita A, Yakushko O, Morgan Consoli ML, Jacobsen S, Mancuso RLL.

Omega (Westport). 2018 Mar;76(4):373-394. doi: 10.1177/0030222817693142. Epub 2017 Feb 21.

PMID:
29284323
34.

Impaired expression of CXCL5 and matrix metalloproteinases in the lungs of mice with high susceptibility to Streptococcus pneumoniae infection.

Mancuso RI, Miyaji EN, Silva CCF, Portaro FV, Soares-Schanoski A, Ribeiro OG, Oliveira MLS.

Immun Inflamm Dis. 2018 Mar;6(1):128-142. doi: 10.1002/iid3.205. Epub 2017 Nov 9.

35.

Endovascular treatment of ruptured pancreaticoduodenal artery aneurysm: The importance of collateral vessels. A case report.

Ricci G, Riu P, Attinà GM, Trombetta S, Ialongo P, Di Cosimo C, Mancuso R, Marini P.

Int J Surg Case Rep. 2017;41:205-208. doi: 10.1016/j.ijscr.2017.10.036. Epub 2017 Oct 26.

36.

Modulation of Immune Responses to Herpes Simplex Virus Type 1 by IFNL3 and IRF7 Polymorphisms: A Study in Alzheimer's Disease.

Costa AS, Agostini S, Guerini FR, Mancuso R, Zanzottera M, Ripamonti E, Racca V, Nemni R, Clerici M.

J Alzheimers Dis. 2017;60(3):1055-1063. doi: 10.3233/JAD-170520.

PMID:
28984602
37.

Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts.

Mancuso R, Amuso R, Armentano B, Grasso G, Rago V, Cappello AR, Galiano F, Figoli A, De Luca G, Hoinkis J, Gabriele B.

Chempluschem. 2017 Oct;82(10):1235-1244. doi: 10.1002/cplu.201700194. Epub 2017 Jun 27.

PMID:
31957996
38.

Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts.

Mancuso R, Amuso R, Armentano B, Grasso G, Rago V, Cappello AR, Galiano F, Figoli A, De Luca G, Hoinkis J, Gabriele B.

Chempluschem. 2017 Oct;82(10):1233-1234. doi: 10.1002/cplu.201700329. Epub 2017 Aug 9.

PMID:
31957992
39.

Prochlorperazine Increases KCC2 Function and Reduces Spasticity after Spinal Cord Injury.

Liabeuf S, Stuhl-Gourmand L, Gackière F, Mancuso R, Sanchez Brualla I, Marino P, Brocard F, Vinay L.

J Neurotrauma. 2017 Dec 15;34(24):3397-3406. doi: 10.1089/neu.2017.5152. Epub 2017 Sep 19.

PMID:
28747093
40.

The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity.

Obst J, Simon E, Mancuso R, Gomez-Nicola D.

Front Aging Neurosci. 2017 Jun 23;9:207. doi: 10.3389/fnagi.2017.00207. eCollection 2017. Review.

41.

Divergent syntheses of iodinated isobenzofuranones and isochromenones by iodolactonization of 2-alkynylbenzoic acids in ionic liquids.

Mancuso R, Pomelli CC, Malafronte F, Maner A, Marino N, Chiappe C, Gabriele B.

Org Biomol Chem. 2017 Jun 7;15(22):4831-4841. doi: 10.1039/c7ob00962c.

PMID:
28534923
42.

Serum iron concentration is associated with subcortical deep gray matter iron levels in multiple sclerosis patients.

Bergsland N, Agostini S, Laganà MM, Mancuso R, Mendozzi L, Tavazzi E, Cecconi P, Clerici M, Baglio F.

Neuroreport. 2017 Aug 2;28(11):645-648. doi: 10.1097/WNR.0000000000000804.

PMID:
28509815
43.

NCAM1 is the Target of miRNA-572: Validation in the Human Oligodendroglial Cell Line.

Mancuso R, Agostini S, Marventano I, Hernis A, Saresella M, Clerici M.

Cell Mol Neurobiol. 2018 Mar;38(2):431-440. doi: 10.1007/s10571-017-0486-0. Epub 2017 Mar 22.

PMID:
28332001
44.

Sigma-1 Receptor in Motoneuron Disease.

Mancuso R, Navarro X.

Adv Exp Med Biol. 2017;964:235-254. doi: 10.1007/978-3-319-50174-1_16. Review.

PMID:
28315275
45.

Synthesis of spiro[isoindole-1,5'-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction.

Giofrè SV, Cirmi S, Mancuso R, Nicolò F, Lanza G, Legnani L, Campisi A, Chiacchio MA, Navarra M, Gabriele B, Romeo R.

Beilstein J Org Chem. 2016 Dec 20;12:2793-2807. doi: 10.3762/bjoc.12.278. eCollection 2016.

46.

Benzofuran-2-acetic ester derivatives induce apoptosis in breast cancer cells by upregulating p21Cip/WAF1 gene expression in p53-independent manner.

Giordano C, Rovito D, Barone I, Mancuso R, Bonofiglio D, Giordano F, Catalano S, Gabriele B, Andò S.

DNA Repair (Amst). 2017 Mar;51:20-30. doi: 10.1016/j.dnarep.2017.01.006. Epub 2017 Jan 15.

PMID:
28108275
47.

Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation.

Clayton EL, Mancuso R, Nielsen TT, Mizielinska S, Holmes H, Powell N, Norona F, Larsen JO, Milioto C, Wilson KM, Lythgoe MF, Ourselin S, Nielsen JE, Johannsen P, Holm I, Collinge J; FReJA, Oliver PL, Gomez-Nicola D, Isaacs AM.

Hum Mol Genet. 2017 Mar 1;26(5):873-887. doi: 10.1093/hmg/ddx003.

48.

A protective role for herpes simplex virus type-1-specific humoral immunity in Alzheimer's Disease.

Agostini S, Mancuso R, Baglio F, Clerici M.

Expert Rev Anti Infect Ther. 2017 Feb;15(2):89-91. doi: 10.1080/14787210.2017.1264271. Epub 2016 Dec 1. No abstract available.

PMID:
27882822
49.

Downstream effect profiles discern different mechanisms of integrin αLβ2 inhibition.

Mancuso RV, Welzenbach K, Steinberger P, Krähenbühl S, Weitz-Schmidt G.

Biochem Pharmacol. 2016 Nov 1;119:42-55. doi: 10.1016/j.bcp.2016.09.002. Epub 2016 Sep 6.

PMID:
27613223
50.

High avidity HSV-1 antibodies correlate with absence of amnestic Mild Cognitive Impairment conversion to Alzheimer's disease.

Agostini S, Mancuso R, Baglio F, Cabinio M, Hernis A, Costa AS, Calabrese E, Nemni R, Clerici M.

Brain Behav Immun. 2016 Nov;58:254-260. doi: 10.1016/j.bbi.2016.07.153. Epub 2016 Jul 25.

PMID:
27470229

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