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Items: 1 to 50 of 87


Composition of heterotrophic specialized sub-guilds defined by a positive RNA and polyhydroxyalkanoate correlation in activated sludge.

Guo B, Manchester M, Luby T, Frigon D.

Water Res. 2018 Nov 1;144:561-571. doi: 10.1016/j.watres.2018.07.059. Epub 2018 Jul 25.


Pharmacodynamic Monitoring of RO5459072, a Small Molecule Inhibitor of Cathepsin S.

Theron M, Bentley D, Nagel S, Manchester M, Gerg M, Schindler T, Silva A, Ecabert B, Teixeira P, Perret C, Reis B.

Front Immunol. 2017 Jul 17;8:806. doi: 10.3389/fimmu.2017.00806. eCollection 2017.


Metabolomics: Strategies to Define the Role of Metabolism in Virus Infection and Pathogenesis.

Manchester M, Anand A.

Adv Virus Res. 2017;98:57-81. doi: 10.1016/bs.aivir.2017.02.001. Epub 2017 Mar 31. Review.


Virus-Based Nanoparticles as Versatile Nanomachines.

Koudelka KJ, Pitek AS, Manchester M, Steinmetz NF.

Annu Rev Virol. 2015 Nov;2(1):379-401. doi: 10.1146/annurev-virology-100114-055141. Epub 2015 Sep 25. Review.


Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain.

Johnson CH, Patti GJ, Courade JP, Shriver LP, Hoang LT, Manchester M, Siuzdak G.

J Neuroimmune Pharmacol. 2015 Sep;10(3):396-401. doi: 10.1007/s11481-015-9624-y. Epub 2015 Aug 2.


Inflammation triggers production of dimethylsphingosine from oligodendrocytes.

Chen YJ, Hill S, Huang H, Taraboletti A, Cho K, Gallo R, Manchester M, Shriver LP, Patti GJ.

Neuroscience. 2014 Oct 24;279:113-21. doi: 10.1016/j.neuroscience.2014.08.011. Epub 2014 Aug 21.


Encapsidated atom-transfer radical polymerization in Qβ virus-like nanoparticles.

Hovlid ML, Lau JL, Breitenkamp K, Higginson CJ, Laufer B, Manchester M, Finn MG.

ACS Nano. 2014 Aug 26;8(8):8003-14. doi: 10.1021/nn502043d. Epub 2014 Jul 29.


Lysine addressability and mammalian cell interactions of bacteriophage λ procapsids.

Koudelka KJ, Ippoliti S, Medina E, Shriver LP, Trauger SA, Catalano CE, Manchester M.

Biomacromolecules. 2013 Dec 9;14(12):4169-76. doi: 10.1021/bm401577f. Epub 2013 Nov 26.


Readily accessible fluorescent probes for sensitive biological imaging of hydrogen peroxide.

Daniel KB, Agrawal A, Manchester M, Cohen SM.

Chembiochem. 2013 Mar 18;14(5):593-8. doi: 10.1002/cbic.201200724. Epub 2013 Feb 21.


A view from above: cloud plots to visualize global metabolomic data.

Patti GJ, Tautenhahn R, Rinehart D, Cho K, Shriver LP, Manchester M, Nikolskiy I, Johnson CH, Mahieu NG, Siuzdak G.

Anal Chem. 2013 Jan 15;85(2):798-804. doi: 10.1021/ac3029745. Epub 2012 Dec 26.


Endocytic uptake pathways utilized by CPMV nanoparticles.

Plummer EM, Manchester M.

Mol Pharm. 2013 Jan 7;10(1):26-32. doi: 10.1021/mp300238w. Epub 2012 Sep 20.


Discovery of a trans-dichloroethene-respiring Dehalogenimonas species in the 1,1,2,2-tetrachloroethane-dechlorinating WBC-2 consortium.

Manchester MJ, Hug LA, Zarek M, Zila A, Edwards EA.

Appl Environ Microbiol. 2012 Aug;78(15):5280-7. doi: 10.1128/AEM.00384-12. Epub 2012 May 25.


Guiding plant virus particles to integrin-displaying cells.

Hovlid ML, Steinmetz NF, Laufer B, Lau JL, Kuzelka J, Wang Q, Hyypiä T, Nemerow GR, Kessler H, Manchester M, Finn MG.

Nanoscale. 2012 Jun 21;4(12):3698-705. doi: 10.1039/c2nr30571b. Epub 2012 May 15.


Delayed toxicity associated with soluble anthrax toxin receptor decoy-Ig fusion protein treatment.

Thomas D, Naughton J, Cote C, Welkos S, Manchester M, Young JA.

PLoS One. 2012;7(4):e34611. doi: 10.1371/journal.pone.0034611. Epub 2012 Apr 12.


Interaction of cowpea mosaic virus nanoparticles with surface vimentin and inflammatory cells in atherosclerotic lesions.

Plummer EM, Thomas D, Destito G, Shriver LP, Manchester M.

Nanomedicine (Lond). 2012 Jun;7(6):877-88. doi: 10.2217/nnm.11.185. Epub 2012 Mar 6.


Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis.

Shriver LP, Manchester M.

Sci Rep. 2011;1:79. doi: 10.1038/srep00079. Epub 2011 Sep 1.


Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin.

Patti GJ, Yanes O, Shriver LP, Courade JP, Tautenhahn R, Manchester M, Siuzdak G.

Nat Chem Biol. 2012 Jan 22;8(3):232-4. doi: 10.1038/nchembio.767.


Multivalent display of proteins on viral nanoparticles using molecular recognition and chemical ligation strategies.

Venter PA, Dirksen A, Thomas D, Manchester M, Dawson PE, Schneemann A.

Biomacromolecules. 2011 Jun 13;12(6):2293-301. doi: 10.1021/bm200369e. Epub 2011 May 13.


Cowpea mosaic virus nanoparticles target surface vimentin on cancer cells.

Steinmetz NF, Cho CF, Ablack A, Lewis JD, Manchester M.

Nanomedicine (Lond). 2011 Feb;6(2):351-64. doi: 10.2217/nnm.10.136.


Transferrin-mediated targeting of bacteriophage HK97 nanoparticles into tumor cells.

Huang RK, Steinmetz NF, Fu CY, Manchester M, Johnson JE.

Nanomedicine (Lond). 2011 Jan;6(1):55-68. doi: 10.2217/nnm.10.99.


Chemically modified viruses: principles and applications.

Koudelka KJ, Manchester M.

Curr Opin Chem Biol. 2010 Dec;14(6):810-7. doi: 10.1016/j.cbpa.2010.10.005. Review.


Labeling live cells by copper-catalyzed alkyne--azide click chemistry.

Hong V, Steinmetz NF, Manchester M, Finn MG.

Bioconjug Chem. 2010 Oct 20;21(10):1912-6. doi: 10.1021/bc100272z.


Viral nanoparticles and virus-like particles: platforms for contemporary vaccine design.

Plummer EM, Manchester M.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011 Mar-Apr;3(2):174-196. doi: 10.1002/wnan.119. Epub 2010 Sep 24. Review.


Intravital imaging of embryonic and tumor neovasculature using viral nanoparticles.

Leong HS, Steinmetz NF, Ablack A, Destito G, Zijlstra A, Stuhlmann H, Manchester M, Lewis JD.

Nat Protoc. 2010 Aug;5(8):1406-17. doi: 10.1038/nprot.2010.103. Epub 2010 Jul 8.


Nanostructure-initiator mass spectrometry (NIMS) imaging of brain cholesterol metabolites in Smith-Lemli-Opitz syndrome.

Patti GJ, Shriver LP, Wassif CA, Woo HK, Uritboonthai W, Apon J, Manchester M, Porter FD, Siuzdak G.

Neuroscience. 2010 Oct 27;170(3):858-64. doi: 10.1016/j.neuroscience.2010.07.038. Epub 2010 Jul 27.


Hydrazone ligation strategy to assemble multifunctional viral nanoparticles for cell imaging and tumor targeting.

Brunel FM, Lewis JD, Destito G, Steinmetz NF, Manchester M, Stuhlmann H, Dawson PE.

Nano Lett. 2010 Mar 10;10(3):1093-7. doi: 10.1021/nl1002526.


Potato virus X as a novel platform for potential biomedical applications.

Steinmetz NF, Mertens ME, Taurog RE, Johnson JE, Commandeur U, Fischer R, Manchester M.

Nano Lett. 2010 Jan;10(1):305-12. doi: 10.1021/nl9035753.


Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging.

Patti GJ, Woo HK, Yanes O, Shriver L, Thomas D, Uritboonthai W, Apon JV, Steenwyk R, Manchester M, Siuzdak G.

Anal Chem. 2010 Jan 1;82(1):121-8. doi: 10.1021/ac9014353.


Interaction of Cowpea mosaic virus (CPMV) nanoparticles with antigen presenting cells in vitro and in vivo.

Gonzalez MJ, Plummer EM, Rae CS, Manchester M.

PLoS One. 2009 Nov 23;4(11):e7981. doi: 10.1371/journal.pone.0007981.


Buckyballs meet viral nanoparticles: candidates for biomedicine.

Steinmetz NF, Hong V, Spoerke ED, Lu P, Breitenkamp K, Finn MG, Manchester M.

J Am Chem Soc. 2009 Dec 2;131(47):17093-5. doi: 10.1021/ja902293w.


Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response.

Wikoff WR, Kalisak E, Trauger S, Manchester M, Siuzdak G.

J Proteome Res. 2009 Jul;8(7):3578-87. doi: 10.1021/pr900275p.


Endothelial targeting of cowpea mosaic virus (CPMV) via surface vimentin.

Koudelka KJ, Destito G, Plummer EM, Trauger SA, Siuzdak G, Manchester M.

PLoS Pathog. 2009 May;5(5):e1000417. doi: 10.1371/journal.ppat.1000417. Epub 2009 May 1.


Viral nanoparticles associate with regions of inflammation and blood brain barrier disruption during CNS infection.

Shriver LP, Koudelka KJ, Manchester M.

J Neuroimmunol. 2009 Jun 25;211(1-2):66-72. doi: 10.1016/j.jneuroim.2009.03.015. Epub 2009 Apr 25.


Tomato bushy stunt virus (TBSV), a versatile platform for polyvalent display of antigenic epitopes and vaccine design.

Kumar S, Ochoa W, Singh P, Hsu C, Schneemann A, Manchester M, Olson M, Reddy V.

Virology. 2009 May 25;388(1):185-90. doi: 10.1016/j.virol.2009.02.051. Epub 2009 Apr 2.


Nanostructure initiator mass spectrometry: tissue imaging and direct biofluid analysis.

Yanes O, Woo HK, Northen TR, Oppenheimer SR, Shriver L, Apon J, Estrada MN, Potchoiba MJ, Steenwyk R, Manchester M, Siuzdak G.

Anal Chem. 2009 Apr 15;81(8):2969-75. doi: 10.1021/ac802576q.


PEGylated viral nanoparticles for biomedicine: the impact of PEG chain length on VNP cell interactions in vitro and ex vivo.

Steinmetz NF, Manchester M.

Biomacromolecules. 2009 Apr 13;10(4):784-92. doi: 10.1021/bm8012742.


Anti-toxin antibodies in prophylaxis and treatment of inhalation anthrax.

Schneemann A, Manchester M.

Future Microbiol. 2009 Feb;4(1):35-43. doi: 10.2217/17460913.4.1.35. Review.


Biomedical nanotechnology using virus-based nanoparticles.

Destito G, Schneemann A, Manchester M.

Curr Top Microbiol Immunol. 2009;327:95-122. Review.


Hybrid assembly of CPMV viruses and surface characteristics of different mutants.

Portney NG, Destito G, Manchester M, Ozkan M.

Curr Top Microbiol Immunol. 2009;327:59-69. Review.


Viruses and nanotechnology. Preface.

Manchester M, Steinmetz NF.

Curr Top Microbiol Immunol. 2009;327:v-vi. No abstract available.


Efficient neutralization of antibody-resistant forms of anthrax toxin by a soluble receptor decoy inhibitor.

Sharma S, Thomas D, Marlett J, Manchester M, Young JA.

Antimicrob Agents Chemother. 2009 Mar;53(3):1210-2. doi: 10.1128/AAC.01294-08. Epub 2008 Dec 15.


Chemical addressability of ultraviolet-inactivated viral nanoparticles (VNPs).

Rae C, Koudelka KJ, Destito G, Estrada MN, Gonzalez MJ, Manchester M.

PLoS One. 2008 Oct 2;3(10):e3315. doi: 10.1371/journal.pone.0003315.


Plasma clearance of bacteriophage Qbeta particles as a function of surface charge.

Prasuhn DE Jr, Singh P, Strable E, Brown S, Manchester M, Finn MG.

J Am Chem Soc. 2008 Jan 30;130(4):1328-34. doi: 10.1021/ja075937f. Epub 2008 Jan 5.


Folic acid-mediated targeting of cowpea mosaic virus particles to tumor cells.

Destito G, Yeh R, Rae CS, Finn MG, Manchester M.

Chem Biol. 2007 Oct;14(10):1152-62.


A viral nanoparticle with dual function as an anthrax antitoxin and vaccine.

Manayani DJ, Thomas D, Dryden KA, Reddy V, Siladi ME, Marlett JM, Rainey GJ, Pique ME, Scobie HM, Yeager M, Young JA, Manchester M, Schneemann A.

PLoS Pathog. 2007 Oct 5;3(10):1422-31.


Bio-distribution, toxicity and pathology of cowpea mosaic virus nanoparticles in vivo.

Singh P, Prasuhn D, Yeh RM, Destito G, Rae CS, Osborn K, Finn MG, Manchester M.

J Control Release. 2007 Jul 16;120(1-2):41-50. Epub 2007 Apr 13.


Amiodarone and bepridil inhibit anthrax toxin entry into host cells.

Sanchez AM, Thomas D, Gillespie EJ, Damoiseaux R, Rogers J, Saxe JP, Huang J, Manchester M, Bradley KA.

Antimicrob Agents Chemother. 2007 Jul;51(7):2403-11. Epub 2007 May 7.


Viral MRI contrast agents: coordination of Gd by native virions and attachment of Gd complexes by azide-alkyne cycloaddition.

Prasuhn DE Jr, Yeh RM, Obenaus A, Manchester M, Finn MG.

Chem Commun (Camb). 2007 Mar 28;(12):1269-71. Epub 2007 Jan 15.


Interaction between a 54-kilodalton mammalian cell surface protein and cowpea mosaic virus.

Koudelka KJ, Rae CS, Gonzalez MJ, Manchester M.

J Virol. 2007 Feb;81(4):1632-40. Epub 2006 Nov 22.

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