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Conserved NPPB+ Border Zone Switches from MEF2 to AP-1 Driven Gene Program.

van Duijvenboden K, de Bakker DEM, Man JCK, Janssen R, Günthel M, Hill MC, Hooijkaas IB, van der Made I, van der Kraak PH, Vink A, Creemers EE, Martin JF, Barnett P, Bakkers J, Christoffels VM.

Circulation. 2019 Jul 1. doi: 10.1161/CIRCULATIONAHA.118.038944. [Epub ahead of print]


Clinical- and surgery-specific risk factors for post-operative sepsis: a systematic review and meta-analysis of over 30 million patients.

Plaeke P, De Man JG, Coenen S, Jorens PG, De Winter BY, Hubens G.

Surg Today. 2019 Jun 6. doi: 10.1007/s00595-019-01827-4. [Epub ahead of print] Review.


Determination of benzonatate and its metabolite in human plasma by HPLC-MS/MS: A preliminary pharmacokinetic study in healthy Chinese volunteers after oral administration of benzonatate soft capsule.

Man J, Jiao F, Wang Y, Gu Y, Ding L, Shu C.

J Pharm Biomed Anal. 2019 Sep 5;173:134-143. doi: 10.1016/j.jpba.2019.05.030. Epub 2019 May 16.


Mas-related G protein-coupled receptor C11 (Mrgprc11) induces visceral hypersensitivity in the mouse colon: A novel target in gut nociception?

Van Remoortel S, Ceuleers H, Arora R, Van Nassauw L, De Man JG, Buckinx R, De Winter BY, Timmermans JP.

Neurogastroenterol Motil. 2019 May 22:e13623. doi: 10.1111/nmo.13623. [Epub ahead of print]


Proposed classification of endoleaks after endovascular treatment of Stanford type-B aortic dissections.

Sharafuddin MJ, Reece TB, Papia G, Pozeg ZI, Peterson BG, Shafi B, Man J, Milner R.

Vascular. 2019 May 8:1708538119847394. doi: 10.1177/1708538119847394. [Epub ahead of print]


A report from a workshop of the International Stem Cell Banking Initiative, held in collaboration GAiT and the Harvard Stem Cell Institute, Boston 2017.

Kim JH, Alderton A, Benvenisty N, Brandsten C, Firpo M, Harrison PW, Kawamata S, Kawase E, Kurtz A, Loring JF, Ludwig T, Man J, Mountford JC, Turner ML, Oh S, da Veiga Pereira L, Pranke P, Sheldon M, Steeg R, Sullivan S, Yaffe M, Zhou Q, Stacey GN.

Stem Cells. 2019 Apr 25. doi: 10.1002/stem.3003. [Epub ahead of print]


Unique Presentation of an Inflammatory Abdominal Aortic Aneurysm With Rhabdomyolysis.

Man JH, Xu J.

EJVES Short Rep. 2019 Apr 7;43:1-3. doi: 10.1016/j.ejvssr.2019.03.001. eCollection 2019.


Evolution of buffering in a genetic circuit controlling plant stem cell proliferation.

Rodriguez-Leal D, Xu C, Kwon CT, Soyars C, Demesa-Arevalo E, Man J, Liu L, Lemmon ZH, Jones DS, Van Eck J, Jackson DP, Bartlett ME, Nimchuk ZL, Lippman ZB.

Nat Genet. 2019 May;51(5):786-792. doi: 10.1038/s41588-019-0389-8. Epub 2019 Apr 15.


NT5DC2 promotes tumorigenicity of glioma stem-like cells by upregulating fyn.

Guo S, Ran H, Xiao D, Huang H, Mi L, Wang X, Chen L, Li D, Zhang S, Han Q, Zhou T, Li A, Man J.

Cancer Lett. 2019 Jul 10;454:98-107. doi: 10.1016/j.canlet.2019.04.003. Epub 2019 Apr 10.


Postoperative continuation of antidepressant therapy is associated with reduced short-term weight loss following Roux-en-Y gastric bypass surgery.

Plaeke P, Van Den Eede F, Gys B, Beunis A, Ruppert M, De Man J, De Winter B, Hubens G.

Langenbecks Arch Surg. 2019 Apr 10. doi: 10.1007/s00423-019-01784-z. [Epub ahead of print]


Erratum for Chen et al., "Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate".

Chen Q, Wu J, Ye Q, Ma F, Zhu Q, Wu Y, Shan C, Xie X, Li D, Zhan X, Li C, Li XF, Qin X, Zhao T, Wu H, Shi PY, Man J, Qin CF.

MBio. 2019 Apr 2;10(2). pii: e00433-19. doi: 10.1128/mBio.00433-19. No abstract available.


Panel-based NGS reveals disease-causing mutations in hearing loss patients using BGISEQ-500 platform.

Sun Y, Yuan J, Wu L, Li M, Cui X, Yan C, Du L, Mao L, Man J, Li W, Kristiansen K, Wu X, Pan W, Yang Y.

Medicine (Baltimore). 2019 Mar;98(12):e14860. doi: 10.1097/MD.0000000000014860.


Diabetes self-management in three different income settings: Cross-learning of barriers and opportunities.

De Man J, Aweko J, Daivadanam M, Alvesson HM, Delobelle P, Mayega RW, Östenson CG, Kirunda B, Kasujja FX, Guwattude D, Puoane T, Sanders D, Peterson S, Tomson G, Sundberg CJ, Absetz P, Van Olmen J.

PLoS One. 2019 Mar 19;14(3):e0213530. doi: 10.1371/journal.pone.0213530. eCollection 2019.


Reply to Q. Wu et al.

Man J, Ritchie G, Links M, Lord S, Lee CK.

Asia Pac J Clin Oncol. 2019 Jun;15(3):191. doi: 10.1111/ajco.13132. Epub 2019 Feb 27. No abstract available.


Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids.

Xu YP, Qiu Y, Zhang B, Chen G, Chen Q, Wang M, Mo F, Xu J, Wu J, Zhang RR, Cheng ML, Zhang NN, Lyu B, Zhu WL, Wu MH, Ye Q, Zhang D, Man JH, Li XF, Cui J, Xu Z, Hu B, Zhou X, Qin CF.

Cell Res. 2019 Apr;29(4):265-273. doi: 10.1038/s41422-019-0152-9. Epub 2019 Feb 27.


Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity.

Dai J, Huang YJ, He X, Zhao M, Wang X, Liu ZS, Xue W, Cai H, Zhan XY, Huang SY, He K, Wang H, Wang N, Sang Z, Li T, Han QY, Mao J, Diao X, Song N, Chen Y, Li WH, Man JH, Li AL, Zhou T, Liu ZG, Zhang XM, Li T.

Cell. 2019 Mar 7;176(6):1447-1460.e14. doi: 10.1016/j.cell.2019.01.016. Epub 2019 Feb 21.


Pathways to diagnosis of non-small cell lung cancer: a descriptive cohort study.

Purdie S, Creighton N, White KM, Baker D, Ewald D, Lee CK, Lyon A, Man J, Michail D, Miller AA, Tan L, Currow D, Young JM.

NPJ Prim Care Respir Med. 2019 Feb 8;29(1):2. doi: 10.1038/s41533-018-0113-7.


Distal landing zone optimization before endovascular repair of aortic dissection.

Sharafuddin MJ, Bhama JK, Bashir M, Aboul-Hosn MS, Man JH, Sharp AJ.

J Thorac Cardiovasc Surg. 2019 Jan;157(1):88-98. doi: 10.1016/j.jtcvs.2018.06.095. Epub 2018 Jul 27.


The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma.

Parkin A, Man J, Chou A, Nagrial AM, Samra J, Gill AJ, Timpson P, Pajic M.

Diseases. 2018 Nov 13;6(4). pii: E103. doi: 10.3390/diseases6040103. Review.


Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017.

Uitdehaag JCM, Kooijman JJ, de Roos JADM, Prinsen MBW, Dylus J, Willemsen-Seegers N, Kawase Y, Sawa M, de Man J, van Gerwen SJC, Buijsman RC, Zaman GJR.

Mol Cancer Ther. 2019 Feb;18(2):470-481. doi: 10.1158/1535-7163.MCT-18-0877. Epub 2018 Oct 31.


Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate.

Chen Q, Wu J, Ye Q, Ma F, Zhu Q, Wu Y, Shan C, Xie X, Li D, Zhan X, Li C, Li XF, Qin X, Zhao T, Wu H, Shi PY, Man J, Qin CF.

MBio. 2018 Sep 18;9(5). pii: e01683-18. doi: 10.1128/mBio.01683-18. Erratum in: MBio. 2019 Apr 2;10(2):. Zhao, Tongyang [corrected to Zhao, Tongyan].


Comparison of bone marrow component removal from processed femoral head bone from living and deceased donors: presence of geodes in living donor bone can prevent maximum removal of marrow components.

Eagle MJ, Man J, Rooney P, Kearney JN.

Cell Tissue Bank. 2018 Dec;19(4):727-732. doi: 10.1007/s10561-018-9726-x. Epub 2018 Sep 11.


Identifying Therapeutic Targets for Sepsis Research: A Characterization Study of the Inflammatory Players in the Cecal Ligation and Puncture Model.

Nullens S, De Man J, Bridts C, Ebo D, Francque S, De Winter B.

Mediators Inflamm. 2018 Aug 5;2018:5130463. doi: 10.1155/2018/5130463. eCollection 2018.


Patient and Provider Dilemmas of Type 2 Diabetes Self-Management: A Qualitative Study in Socioeconomically Disadvantaged Communities in Stockholm.

Aweko J, De Man J, Absetz P, Östenson CG, Swartling Peterson S, Mölsted Alvesson H, Daivadanam M.

Int J Environ Res Public Health. 2018 Aug 22;15(9). pii: E1810. doi: 10.3390/ijerph15091810.


Service satisfaction and helpfulness ratings, mental health literacy and help seeking barriers of carers of individuals with dual disabilities.

Man J, Kangas M.

J Appl Res Intellect Disabil. 2019 Jan;32(1):184-193. doi: 10.1111/jar.12520. Epub 2018 Aug 13.


Targeted next-generation sequencing as a comprehensive test for Mendelian diseases: a cohort diagnostic study.

Sun Y, Man J, Wan Y, Pan G, Du L, Li L, Yang Y, Qiu L, Gao Q, Dan H, Mao L, Cheng Z, Fan C, Yu J, Lin M, Kristiansen K, Shen Y, Wei X.

Sci Rep. 2018 Aug 3;8(1):11646. doi: 10.1038/s41598-018-30151-z.


Comparative study for microcystin-LR sorption onto biochars produced from various plant- and animal-wastes at different pyrolysis temperatures: Influencing mechanisms of biochar properties.

Li J, Cao L, Yuan Y, Wang R, Wen Y, Man J.

Bioresour Technol. 2018 Jan;247:794-803. doi: 10.1016/j.biortech.2017.09.120. Epub 2017 Sep 20.


Cell reprogramming approaches in gene- and cell-based therapies for Parkinson's disease.

Man JHK, Groenink L, Caiazzo M.

J Control Release. 2018 Sep 28;286:114-124. doi: 10.1016/j.jconrel.2018.07.017. Epub 2018 Jul 17.


A phosphoproteomic signature in endothelial cells predicts vascular toxicity of tyrosine kinase inhibitors used in CML.

Gopal S, Lu Q, Man JJ, Baur W, Rao SP, Litichevskiy L, Papanastasiou M, Creech AL, DeRuff KC, Mullahoo J, Officer A, Egri SB, Davison D, Jaffe JD, Jaffe IZ.

Blood Adv. 2018 Jul 24;2(14):1680-1684. doi: 10.1182/bloodadvances.2018020396. No abstract available.


Patients experiences of self-management and strategies for dealing with chronic conditions in rural Malawi.

Angwenyi V, Aantjes C, Kajumi M, De Man J, Criel B, Bunders-Aelen J.

PLoS One. 2018 Jul 2;13(7):e0199977. doi: 10.1371/journal.pone.0199977. eCollection 2018.


Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors.

Hoque M, Abbassi RH, Froio D, Man J, Johns TG, Stringer BW, Day BW, Pajic M, Kassiou M, Munoz L.

Pharmacol Res. 2018 Aug;134:166-178. doi: 10.1016/j.phrs.2018.06.023. Epub 2018 Jun 23.


Endovascular management of an acute type B aortic dissection in a patient with fibromuscular dysplasia.

Man JH, Rothstein A, Patel PJ, Lee CJ.

J Vasc Surg Cases Innov Tech. 2018 Apr 12;4(2):76-79. doi: 10.1016/j.jvscit.2017.12.012. eCollection 2018 Jun.


Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.

Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J.

J Neuroinflammation. 2018 Jun 21;15(1):188. doi: 10.1186/s12974-018-1226-1.


Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome.

Ceuleers H, Hanning N, Heirbaut J, Van Remoortel S, Joossens J, Van Der Veken P, Francque SM, De Bruyn M, Lambeir AM, De Man JG, Timmermans JP, Augustyns K, De Meester I, De Winter BY.

Br J Pharmacol. 2018 Sep;175(17):3516-3533. doi: 10.1111/bph.14396. Epub 2018 Jul 23.


Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway.

Ng L, Chow AKM, Man JHW, Yau TCC, Wan TMH, Iyer DN, Kwan VHT, Poon RTP, Pang RWC, Law WL.

BMC Cancer. 2018 Jun 1;18(1):621. doi: 10.1186/s12885-018-4326-5.


Huntington's Disease Outpatient Clinic for Functional Diagnosis and Treatment: Coming to Consensus: How Long Term Care Facility Procedures Complement Specialist Diagnosis and Treatment.

Veenhuizen R, Nijsten H, van Roosmalen P, Lammertsen K, Stor T, de Jager L, de Man J, van der Doelen R, Landa K, Grond V, Heffels J, Groenewoud R, Rovers L, Bakker C, Leiwakabessy S, van der Wedden D, van Blitterswijk J, van den Bosch D.

J Huntingtons Dis. 2018;7(2):189-191. doi: 10.3233/JHD-180298.


Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure.

Li J, Man J, Li Z, Chen H.

J Vis Exp. 2018 Apr 17;(134). doi: 10.3791/57313.


Hydrodynamically Formed Uniform Thick Coatings on Microspheres.

Liang S, Li J, Xu Q, Man J, Chen H.

Small. 2018 Jun;14(23):e1800613. doi: 10.1002/smll.201800613. Epub 2018 May 2.


Competence Enhancement Program of Expressive Arts in End-of-Life Care for Health and Social Care Professionals: A Mixed-Method Evaluation.

Nan JKM, Lau BH, Szeto MML, Lam KKF, Man JCN, Chan CLW.

Am J Hosp Palliat Care. 2018 Sep;35(9):1207-1214. doi: 10.1177/1049909118765410. Epub 2018 Apr 5.


Impact of Menopause on Quality of Life in Community-based Women in China: 1 Year Follow-up.

Sun N, Xing J, Li L, Han XY, Man J, Wang HY, Lv DM.

Arch Psychiatr Nurs. 2018 Apr;32(2):224-228. doi: 10.1016/j.apnu.2017.11.005. Epub 2017 Nov 6.


Defining the Most Appropriate Primary End Point in Phase 2 Trials of Immune Checkpoint Inhibitors for Advanced Solid Cancers: A Systematic Review and Meta-analysis.

Ritchie G, Gasper H, Man J, Lord S, Marschner I, Friedlander M, Lee CK.

JAMA Oncol. 2018 Apr 1;4(4):522-528. doi: 10.1001/jamaoncol.2017.5236.


Rates of latent tuberculosis infection in patients treated with TNF inhibitors for psoriasis: a retrospective chart review.

Lee EB, Amin M, Man J, Egeberg A, Wu JJ.

J Dermatolog Treat. 2018 Nov;29(7):671-675. doi: 10.1080/09546634.2018.1443198. Epub 2018 Mar 22.


Size-Dependent Phase Separation in Emulsion Droplets.

Man J, Chien S, Liang S, Li J, Chen H.

Chemphyschem. 2018 Aug 17;19(16):1995-1998. doi: 10.1002/cphc.201701296. Epub 2018 Feb 19.


Treatment-related toxicities of immune checkpoint inhibitors in advanced cancers: A meta-analysis.

Man J, Ritchie G, Links M, Lord S, Lee CK.

Asia Pac J Clin Oncol. 2018 Jun;14(3):141-152. doi: 10.1111/ajco.12838. Epub 2018 Jan 19.


Severe steatosis induces portal hypertension by systemic arterial hyporeactivity and hepatic vasoconstrictor hyperreactivity in rats.

Van der Graaff D, Kwanten WJ, Couturier FJ, Govaerts JS, Verlinden W, Brosius I, D'Hondt M, Driessen A, De Winter BY, De Man JG, Michielsen PP, Francque SM.

Lab Invest. 2018 Oct;98(10):1263-1275. doi: 10.1038/s41374-017-0018-z. Epub 2018 Jan 11.


Structure and function of the Nppa-Nppb cluster locus during heart development and disease.

Man J, Barnett P, Christoffels VM.

Cell Mol Life Sci. 2018 Apr;75(8):1435-1444. doi: 10.1007/s00018-017-2737-0. Epub 2018 Jan 4. Review.


Clinical and Molecular Characteristics Associated With Survival Among Patients Treated With Checkpoint Inhibitors for Advanced Non-Small Cell Lung Carcinoma: A Systematic Review and Meta-analysis.

Lee CK, Man J, Lord S, Cooper W, Links M, Gebski V, Herbst RS, Gralla RJ, Mok T, Yang JC.

JAMA Oncol. 2018 Feb 1;4(2):210-216. doi: 10.1001/jamaoncol.2017.4427.


The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury.

Campana L, Starkey Lewis PJ, Pellicoro A, Aucott RL, Man J, O'Duibhir E, Mok SE, Ferreira-Gonzalez S, Livingstone E, Greenhalgh SN, Hull KL, Kendall TJ, Vernimmen D, Henderson NC, Boulter L, Gregory CD, Feng Y, Anderton SM, Forbes SJ, Iredale JP.

J Immunol. 2018 Feb 1;200(3):1169-1187. doi: 10.4049/jimmunol.1701247. Epub 2017 Dec 20.


Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells.

Man J, Yu X, Huang H, Zhou W, Xiang C, Huang H, Miele L, Liu Z, Bebek G, Bao S, Yu JS.

Cell Stem Cell. 2018 Jan 4;22(1):104-118.e6. doi: 10.1016/j.stem.2017.10.005. Epub 2017 Nov 30.

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