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Items: 1 to 50 of 65

1.

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.

Buitinga M, Callebaut A, Marques Câmara Sodré F, Crèvecoeur I, Blahnik-Fagan G, Yang ML, Bugliani M, Arribas-Layton D, Marré M, Cook DP, Waelkens E, Mallone R, Piganelli JD, Marchetti P, Mamula MJ, Derua R, James EA, Mathieu C, Overbergh L.

Diabetes. 2018 Nov;67(11):2337-2348. doi: 10.2337/db18-0295.

2.

Epidermal growth factor receptor peptide vaccination induces cross-reactive immunity to human EGFR, HER2, and HER3.

Doyle HA, Koski RA, Bonafé N, Bruck RA, Tagliatela SM, Gee RJ, Mamula MJ.

Cancer Immunol Immunother. 2018 Oct;67(10):1559-1569. doi: 10.1007/s00262-018-2218-9. Epub 2018 Jul 28.

PMID:
30056598
3.

Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance.

James EA, Pietropaolo M, Mamula MJ.

Diabetes. 2018 Jun;67(6):1035-1042. doi: 10.2337/dbi17-0030. Review.

4.

Oxidative Modifications in Tissue Pathology and Autoimmune Disease.

Yang ML, Doyle HA, Clarke SG, Herold KC, Mamula MJ.

Antioxid Redox Signal. 2018 Nov 10;29(14):1415-1431. doi: 10.1089/ars.2017.7382. Epub 2017 Dec 11. Review.

5.

Humanized mice as a model for aberrant responses in human T cell immunotherapy.

Vudattu NK, Waldron-Lynch F, Truman LA, Deng S, Preston-Hurlburt P, Torres R, Raycroft MT, Mamula MJ, Herold KC.

J Immunol. 2014 Jul 15;193(2):587-96. doi: 10.4049/jimmunol.1302455. Epub 2014 Jun 18.

6.

Editorial: B cells: not just making immunoglobulin anymore.

Mamula MJ.

Arthritis Rheumatol. 2014 Jan;66(1):2-5. doi: 10.1002/art.38208. No abstract available.

7.

Transfer of antigen from human B cells to dendritic cells.

Harvey BP, Raycroft MT, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ.

Mol Immunol. 2014 Mar;58(1):56-65. doi: 10.1016/j.molimm.2013.10.013. Epub 2013 Dec 3.

8.

Autoantigens: novel forms and presentation to the immune system.

Doyle HA, Yang ML, Raycroft MT, Gee RJ, Mamula MJ.

Autoimmunity. 2014 Jun;47(4):220-33. doi: 10.3109/08916934.2013.850495. Epub 2013 Nov 5. Review.

PMID:
24191689
9.

Lupus autoimmunity altered by cellular methylation metabolism.

Yang ML, Gee AJ, Gee RJ, Zurita-Lopez CI, Khare S, Clarke SG, Mamula MJ.

Autoimmunity. 2013 Feb;46(1):21-31. doi: 10.3109/08916934.2012.732133. Epub 2012 Nov 1.

10.

Autoimmunity to isomerized histone H2B in systemic lupus erythematosus.

Doyle HA, Aswad DW, Mamula MJ.

Autoimmunity. 2013 Feb;46(1):6-13. doi: 10.3109/08916934.2012.710859. Epub 2012 Dec 3.

11.

Inhibition of antigen trafficking through scavenger receptor A.

Raycroft MT, Harvey BP, Bruck MJ, Mamula MJ.

J Biol Chem. 2012 Feb 17;287(8):5310-6. doi: 10.1074/jbc.M111.316356. Epub 2012 Jan 3.

12.

Autoantigenesis: the evolution of protein modifications in autoimmune disease.

Doyle HA, Mamula MJ.

Curr Opin Immunol. 2012 Feb;24(1):112-8. doi: 10.1016/j.coi.2011.12.003. Epub 2011 Dec 29. Review.

13.

Characterization of a novel gain of function glucocorticoid receptor knock-in mouse.

Zhang J, Ge R, Matte-Martone C, Goodwin J, Shlomchik WD, Mamula MJ, Kooshkabadi A, Hardy MP, Geller D.

J Biol Chem. 2009 Mar 6;284(10):6249-59. doi: 10.1074/jbc.M807997200. Epub 2008 Nov 18.

14.

Editing antigen presentation: antigen transfer between human B lymphocytes and macrophages mediated by class A scavenger receptors.

Harvey BP, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ.

J Immunol. 2008 Sep 15;181(6):4043-51.

15.

Antigen presentation and transfer between B cells and macrophages.

Harvey BP, Gee RJ, Haberman AM, Shlomchik MJ, Mamula MJ.

Eur J Immunol. 2007 Jul;37(7):1739-51.

16.

Altered immunogenicity of isoaspartate containing proteins.

Doyle HA, Gee RJ, Mamula MJ.

Autoimmunity. 2007 Mar;40(2):131-7.

PMID:
17453712
17.

Intracellular protein modification associated with altered T cell functions in autoimmunity.

Yang ML, Doyle HA, Gee RJ, Lowenson JD, Clarke S, Lawson BR, Aswad DW, Mamula MJ.

J Immunol. 2006 Oct 1;177(7):4541-9. Erratum in: J Immunol. 2006 Dec 15;177(12):8878.

18.

B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation.

Yan J, Harvey BP, Gee RJ, Shlomchik MJ, Mamula MJ.

J Immunol. 2006 Oct 1;177(7):4481-7.

19.

Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain.

Zhu JX, Doyle HA, Mamula MJ, Aswad DW.

J Biol Chem. 2006 Nov 3;281(44):33802-13. Epub 2006 Sep 7.

20.

Isoaspartyl post-translational modification triggers anti-tumor T and B lymphocyte immunity.

Doyle HA, Zhou J, Wolff MJ, Harvey BP, Roman RM, Gee RJ, Koski RA, Mamula MJ.

J Biol Chem. 2006 Oct 27;281(43):32676-83. Epub 2006 Sep 1.

21.

Autoimmune odyssey on the Aegean Sea.

Mamula MJ, Farber DL, Tsokos GC.

Nat Immunol. 2006 Mar;7(3):219-21. No abstract available.

PMID:
16482164
22.

Synapsin I is a major endogenous substrate for protein L-isoaspartyl methyltransferase in mammalian brain.

Reissner KJ, Paranandi MV, Luc TM, Doyle HA, Mamula MJ, Lowenson JD, Aswad DW.

J Biol Chem. 2006 Mar 31;281(13):8389-98. Epub 2006 Jan 27.

23.

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ, Christensen SR, Shlomchik MJ, Viglianti GA, Rifkin IR, Marshak-Rothstein A.

J Exp Med. 2005 Nov 7;202(9):1171-7. Epub 2005 Oct 31.

24.

Posttranslational modifications of self-antigens.

Doyle HA, Mamula MJ.

Ann N Y Acad Sci. 2005 Jun;1050:1-9. Review.

PMID:
16014515
25.

Targeting antigen to CD19 on B cells efficiently activates T cells.

Yan J, Wolff MJ, Unternaehrer J, Mellman I, Mamula MJ.

Int Immunol. 2005 Jul;17(7):869-77. Epub 2005 Jun 20.

PMID:
15967786
26.

Protein L-isoaspartyl methyltransferase catalyzes in vivo racemization of Aspartate-25 in mammalian histone H2B.

Young GW, Hoofring SA, Mamula MJ, Doyle HA, Bunick GJ, Hu Y, Aswad DW.

J Biol Chem. 2005 Jul 15;280(28):26094-8. Epub 2005 May 20.

27.
28.
29.

B and T cell tolerance and autoimmunity in autoantibody transgenic mice.

Yan J, Mamula MJ.

Int Immunol. 2002 Aug;14(8):963-71.

PMID:
12147633
30.

Posttranslational protein modifications: new flavors in the menu of autoantigens.

Doyle HA, Mamula MJ.

Curr Opin Rheumatol. 2002 May;14(3):244-9. Review.

PMID:
11981321
32.

From T to B and back again: positive feedback in systemic autoimmune disease.

Shlomchik MJ, Craft JE, Mamula MJ.

Nat Rev Immunol. 2001 Nov;1(2):147-53. Review.

PMID:
11905822
33.

Lupus autoantigens: their origins, forms, and presentation.

Doyle HA, Yan J, Liang B, Mamula MJ.

Immunol Res. 2001;24(2):131-47. Review.

PMID:
11594452
34.

Structural integrity of histone H2B in vivo requires the activity of protein L-isoaspartate O-methyltransferase, a putative protein repair enzyme.

Young AL, Carter WG, Doyle HA, Mamula MJ, Aswad DW.

J Biol Chem. 2001 Oct 5;276(40):37161-5. Epub 2001 Jul 30.

35.

Post-translational protein modifications in antigen recognition and autoimmunity.

Doyle HA, Mamula MJ.

Trends Immunol. 2001 Aug;22(8):443-9. Review.

PMID:
11473834
36.

Molecular mimicry and the role of B lymphocytes in the processing of autoantigens.

Liang B, Mamula MJ.

Cell Mol Life Sci. 2000 Apr;57(4):561-8. Review.

PMID:
11130456
37.

Autoantibody responses and pathology regulated by B7-1 and B7-2 costimulation in MRL/lpr lupus.

Liang B, Kashgarian MJ, Sharpe AH, Mamula MJ.

J Immunol. 2000 Sep 15;165(6):3436-43.

38.
39.

Isoaspartyl post-translational modification triggers autoimmune responses to self-proteins.

Mamula MJ, Gee RJ, Elliott JI, Sette A, Southwood S, Jones PJ, Blier PR.

J Biol Chem. 1999 Aug 6;274(32):22321-7.

40.

T cell autoimmunity in Ig transgenic mice.

Shinde S, Gee R, Santulli-Marotto S, Bockenstedt LK, Clarke SH, Mamula MJ.

J Immunol. 1999 Jun 15;162(12):7519-24.

41.

Advances in autoantibodies in SLE.

von Mühlen CA, Chan EK, Anglés-Cano E, Mamula MJ, Garcia-De La Torre I, Fritzler MJ.

Lupus. 1998;7(8):507-14. Review. No abstract available.

PMID:
9863891
42.
43.

Autoreactive B cell regulation: peripheral induction of developmental arrest by lupus-associated autoantigens.

Santulli-Marotto S, Retter MW, Gee R, Mamula MJ, Clarke SH.

Immunity. 1998 Feb;8(2):209-19.

44.
45.

B lymphocytes as autoantigen-presenting cells in the amplification of autoimmunity.

Roth R, Gee RJ, Mamula MJ.

Ann N Y Acad Sci. 1997 Apr 5;815:88-104.

PMID:
9186642
46.

B7 costimulation and autoantigen specificity enable B cells to activate autoreactive T cells.

Roth R, Nakamura T, Mamula MJ.

J Immunol. 1996 Oct 1;157(7):2924-31.

PMID:
8816398
47.

Lupus autoimmunity: from peptides to particles.

Mamula MJ.

Immunol Rev. 1995 Apr;144:301-14. Review. No abstract available.

PMID:
7590818
48.

Self-peptides in the initiation of lupus autoimmunity.

Bockenstedt LK, Gee RJ, Mamula MJ.

J Immunol. 1995 Apr 1;154(7):3516-24.

PMID:
7534800
49.

The expression of self antigenic determinants: implications for tolerance and autoimmunity.

Mamula MJ, Craft J.

Curr Opin Immunol. 1994 Dec;6(6):882-6. Review.

PMID:
7536009

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