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Items: 1 to 50 of 79

1.

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.

Buitinga M, Callebaut A, Marques Câmara Sodré F, Crèvecoeur I, Blahnik-Fagan G, Yang ML, Bugliani M, Arribas-Layton D, Marré M, Cook DP, Waelkens E, Mallone R, Piganelli JD, Marchetti P, Mamula MJ, Derua R, James EA, Mathieu C, Overbergh L.

Diabetes. 2018 Nov;67(11):2337-2348. doi: 10.2337/db18-0295.

2.

Epidermal growth factor receptor peptide vaccination induces cross-reactive immunity to human EGFR, HER2, and HER3.

Doyle HA, Koski RA, Bonafé N, Bruck RA, Tagliatela SM, Gee RJ, Mamula MJ.

Cancer Immunol Immunother. 2018 Oct;67(10):1559-1569. doi: 10.1007/s00262-018-2218-9. Epub 2018 Jul 28.

PMID:
30056598
3.

Macrophage Migration Inhibitory Factor Regulates U1 Small Nuclear RNP Immune Complex-Mediated Activation of the NLRP3 Inflammasome.

Shin MS, Kang Y, Wahl ER, Park HJ, Lazova R, Leng L, Mamula M, Krishnaswamy S, Bucala R, Kang I.

Arthritis Rheumatol. 2019 Jan;71(1):109-120. doi: 10.1002/art.40672. Epub 2018 Dec 4.

PMID:
30009530
4.

Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance.

James EA, Pietropaolo M, Mamula MJ.

Diabetes. 2018 Jun;67(6):1035-1042. doi: 10.2337/dbi17-0030. Review.

5.

Microbiota control immune regulation in humanized mice.

Gülden E, Vudattu NK, Deng S, Preston-Hurlburt P, Mamula M, Reed JC, Mohandas S, Herold BC, Torres R, Vieira SM, Lim B, Herazo-Maya JD, Kriegel M, Goodman AL, Cotsapas C, Herold KC.

JCI Insight. 2017 Nov 2;2(21). pii: 91709. doi: 10.1172/jci.insight.91709.

6.

Oxidative Modifications in Tissue Pathology and Autoimmune Disease.

Yang ML, Doyle HA, Clarke SG, Herold KC, Mamula MJ.

Antioxid Redox Signal. 2018 Nov 10;29(14):1415-1431. doi: 10.1089/ars.2017.7382. Epub 2017 Dec 11. Review.

7.

Semi-automated detection of anterior cruciate ligament injury from MRI.

Štajduhar I, Mamula M, Miletić D, Ünal G.

Comput Methods Programs Biomed. 2017 Mar;140:151-164. doi: 10.1016/j.cmpb.2016.12.006. Epub 2016 Dec 15.

PMID:
28254071
8.

The role for neutrophil extracellular traps in cystic fibrosis autoimmunity.

Skopelja S, Hamilton BJ, Jones JD, Yang ML, Mamula M, Ashare A, Gifford AH, Rigby WF.

JCI Insight. 2016 Oct 20;1(17):e88912. doi: 10.1172/jci.insight.88912.

9.

Borrelia miyamotoi sensu lato seroreactivity and seroprevalence in the northeastern United States.

Krause PJ, Narasimhan S, Wormser GP, Barbour AG, Platonov AE, Brancato J, Lepore T, Dardick K, Mamula M, Rollend L, Steeves TK, Diuk-Wasser M, Usmani-Brown S, Williamson P, Sarksyan DS, Fikrig E, Fish D; Tick Borne Diseases Group.

Emerg Infect Dis. 2014 Jul;20(7):1183-90. doi: 10.3201/eid2007.131587.

10.

Humanized mice as a model for aberrant responses in human T cell immunotherapy.

Vudattu NK, Waldron-Lynch F, Truman LA, Deng S, Preston-Hurlburt P, Torres R, Raycroft MT, Mamula MJ, Herold KC.

J Immunol. 2014 Jul 15;193(2):587-96. doi: 10.4049/jimmunol.1302455. Epub 2014 Jun 18.

11.

Editorial: B cells: not just making immunoglobulin anymore.

Mamula MJ.

Arthritis Rheumatol. 2014 Jan;66(1):2-5. doi: 10.1002/art.38208. No abstract available.

12.

Transfer of antigen from human B cells to dendritic cells.

Harvey BP, Raycroft MT, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ.

Mol Immunol. 2014 Mar;58(1):56-65. doi: 10.1016/j.molimm.2013.10.013. Epub 2013 Dec 3.

13.

Autoantigens: novel forms and presentation to the immune system.

Doyle HA, Yang ML, Raycroft MT, Gee RJ, Mamula MJ.

Autoimmunity. 2014 Jun;47(4):220-33. doi: 10.3109/08916934.2013.850495. Epub 2013 Nov 5. Review.

PMID:
24191689
14.

[The role of core decompression for the treatment of femoral head avascular necrosis in renal transplant recipients].

Zivcić-Cosić S, Stalekar H, Mamula M, Miletić D, Orlić L, Racki S, Cicvarić T.

Acta Med Croatica. 2012 Oct;66 Suppl 2:76-80. Croatian.

PMID:
23513422
15.

Lupus autoimmunity altered by cellular methylation metabolism.

Yang ML, Gee AJ, Gee RJ, Zurita-Lopez CI, Khare S, Clarke SG, Mamula MJ.

Autoimmunity. 2013 Feb;46(1):21-31. doi: 10.3109/08916934.2012.732133. Epub 2012 Nov 1.

16.

Autoimmunity to isomerized histone H2B in systemic lupus erythematosus.

Doyle HA, Aswad DW, Mamula MJ.

Autoimmunity. 2013 Feb;46(1):6-13. doi: 10.3109/08916934.2012.710859. Epub 2012 Dec 3.

17.

Inhibition of antigen trafficking through scavenger receptor A.

Raycroft MT, Harvey BP, Bruck MJ, Mamula MJ.

J Biol Chem. 2012 Feb 17;287(8):5310-6. doi: 10.1074/jbc.M111.316356. Epub 2012 Jan 3.

18.

Autoantigenesis: the evolution of protein modifications in autoimmune disease.

Doyle HA, Mamula MJ.

Curr Opin Immunol. 2012 Feb;24(1):112-8. doi: 10.1016/j.coi.2011.12.003. Epub 2011 Dec 29. Review.

19.

Maternal and fetal outcomes in grand multiparous women.

Severinski NS, Mamula O, Severinski S, Mamula M.

Int J Gynaecol Obstet. 2009 Oct;107(1):63-4. doi: 10.1016/j.ijgo.2009.05.011. Epub 2009 Jun 17. No abstract available.

PMID:
19539289
20.

Characterization of a novel gain of function glucocorticoid receptor knock-in mouse.

Zhang J, Ge R, Matte-Martone C, Goodwin J, Shlomchik WD, Mamula MJ, Kooshkabadi A, Hardy MP, Geller D.

J Biol Chem. 2009 Mar 6;284(10):6249-59. doi: 10.1074/jbc.M807997200. Epub 2008 Nov 18.

21.

Editing antigen presentation: antigen transfer between human B lymphocytes and macrophages mediated by class A scavenger receptors.

Harvey BP, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ.

J Immunol. 2008 Sep 15;181(6):4043-51.

22.

Antigen presentation and transfer between B cells and macrophages.

Harvey BP, Gee RJ, Haberman AM, Shlomchik MJ, Mamula MJ.

Eur J Immunol. 2007 Jul;37(7):1739-51.

23.

Altered immunogenicity of isoaspartate containing proteins.

Doyle HA, Gee RJ, Mamula MJ.

Autoimmunity. 2007 Mar;40(2):131-7.

PMID:
17453712
24.

Intracellular protein modification associated with altered T cell functions in autoimmunity.

Yang ML, Doyle HA, Gee RJ, Lowenson JD, Clarke S, Lawson BR, Aswad DW, Mamula MJ.

J Immunol. 2006 Oct 1;177(7):4541-9. Erratum in: J Immunol. 2006 Dec 15;177(12):8878.

25.

B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation.

Yan J, Harvey BP, Gee RJ, Shlomchik MJ, Mamula MJ.

J Immunol. 2006 Oct 1;177(7):4481-7.

26.

Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain.

Zhu JX, Doyle HA, Mamula MJ, Aswad DW.

J Biol Chem. 2006 Nov 3;281(44):33802-13. Epub 2006 Sep 7.

27.

Isoaspartyl post-translational modification triggers anti-tumor T and B lymphocyte immunity.

Doyle HA, Zhou J, Wolff MJ, Harvey BP, Roman RM, Gee RJ, Koski RA, Mamula MJ.

J Biol Chem. 2006 Oct 27;281(43):32676-83. Epub 2006 Sep 1.

28.

Toll-like receptor engagement stimulates anti-snRNP autoreactive B cells for activation.

Ding C, Wang L, Al-Ghawi H, Marroquin J, Mamula M, Yan J.

Eur J Immunol. 2006 Aug;36(8):2013-24.

29.

Autoimmune odyssey on the Aegean Sea.

Mamula MJ, Farber DL, Tsokos GC.

Nat Immunol. 2006 Mar;7(3):219-21. No abstract available.

PMID:
16482164
30.

Synapsin I is a major endogenous substrate for protein L-isoaspartyl methyltransferase in mammalian brain.

Reissner KJ, Paranandi MV, Luc TM, Doyle HA, Mamula MJ, Lowenson JD, Aswad DW.

J Biol Chem. 2006 Mar 31;281(13):8389-98. Epub 2006 Jan 27.

31.

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ, Christensen SR, Shlomchik MJ, Viglianti GA, Rifkin IR, Marshak-Rothstein A.

J Exp Med. 2005 Nov 7;202(9):1171-7. Epub 2005 Oct 31.

32.

Posttranslational modifications of self-antigens.

Doyle HA, Mamula MJ.

Ann N Y Acad Sci. 2005 Jun;1050:1-9. Review.

PMID:
16014515
33.

Targeting antigen to CD19 on B cells efficiently activates T cells.

Yan J, Wolff MJ, Unternaehrer J, Mellman I, Mamula MJ.

Int Immunol. 2005 Jul;17(7):869-77. Epub 2005 Jun 20.

PMID:
15967786
34.

Protein L-isoaspartyl methyltransferase catalyzes in vivo racemization of Aspartate-25 in mammalian histone H2B.

Young GW, Hoofring SA, Mamula MJ, Doyle HA, Bunick GJ, Hu Y, Aswad DW.

J Biol Chem. 2005 Jul 15;280(28):26094-8. Epub 2005 May 20.

35.

Borrelia burgdorferi changes its surface antigenic expression in response to host immune responses.

Liang FT, Yan J, Mbow ML, Sviat SL, Gilmore RD, Mamula M, Fikrig E.

Infect Immun. 2004 Oct;72(10):5759-67.

36.
37.

IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection.

Wang T, Scully E, Yin Z, Kim JH, Wang S, Yan J, Mamula M, Anderson JF, Craft J, Fikrig E.

J Immunol. 2003 Sep 1;171(5):2524-31.

38.

Memory CD4+ T cells do not induce graft-versus-host disease.

Anderson BE, McNiff J, Yan J, Doyle H, Mamula M, Shlomchik MJ, Shlomchik WD.

J Clin Invest. 2003 Jul;112(1):101-8.

39.
40.

B and T cell tolerance and autoimmunity in autoantibody transgenic mice.

Yan J, Mamula MJ.

Int Immunol. 2002 Aug;14(8):963-71.

PMID:
12147633
41.

Posttranslational protein modifications: new flavors in the menu of autoantigens.

Doyle HA, Mamula MJ.

Curr Opin Rheumatol. 2002 May;14(3):244-9. Review.

PMID:
11981321
43.

From T to B and back again: positive feedback in systemic autoimmune disease.

Shlomchik MJ, Craft JE, Mamula MJ.

Nat Rev Immunol. 2001 Nov;1(2):147-53. Review.

PMID:
11905822
44.

Lupus autoantigens: their origins, forms, and presentation.

Doyle HA, Yan J, Liang B, Mamula MJ.

Immunol Res. 2001;24(2):131-47. Review.

PMID:
11594452
45.

Structural integrity of histone H2B in vivo requires the activity of protein L-isoaspartate O-methyltransferase, a putative protein repair enzyme.

Young AL, Carter WG, Doyle HA, Mamula MJ, Aswad DW.

J Biol Chem. 2001 Oct 5;276(40):37161-5. Epub 2001 Jul 30.

46.

Post-translational protein modifications in antigen recognition and autoimmunity.

Doyle HA, Mamula MJ.

Trends Immunol. 2001 Aug;22(8):443-9. Review.

PMID:
11473834
47.

Molecular mimicry and the role of B lymphocytes in the processing of autoantigens.

Liang B, Mamula MJ.

Cell Mol Life Sci. 2000 Apr;57(4):561-8. Review.

PMID:
11130456
48.

Autoantibody responses and pathology regulated by B7-1 and B7-2 costimulation in MRL/lpr lupus.

Liang B, Kashgarian MJ, Sharpe AH, Mamula MJ.

J Immunol. 2000 Sep 15;165(6):3436-43.

49.
50.

Isoaspartyl post-translational modification triggers autoimmune responses to self-proteins.

Mamula MJ, Gee RJ, Elliott JI, Sette A, Southwood S, Jones PJ, Blier PR.

J Biol Chem. 1999 Aug 6;274(32):22321-7.

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