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Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1.

Mammoto T, Torisawa YS, Muyleart M, Hendee K, Anugwom C, Gutterman D, Mammoto A.

Aging (Albany NY). 2019 Sep 5;11(17):7051-7069. doi: 10.18632/aging.102236. Epub 2019 Sep 5.


Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models.

Papa AL, Jiang A, Korin N, Chen MB, Langan ET, Waterhouse A, Nash E, Caroff J, Graveline A, Vernet A, Mammoto A, Mammoto T, Jain A, Kamm RD, Gounis MJ, Ingber DE.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaau5898. doi: 10.1126/scitranslmed.aau5898.


LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung.

Mammoto A, Muyleart M, Mammoto T.

Aging (Albany NY). 2019 Jan 5;11(1):89-103. doi: 10.18632/aging.101722.


Prevalence of curable and pseudoarthrosis stages of adolescent lumbar spondylolysis.

Tatsumura M, Gamada H, Ishimoto R, Okuwaki S, Eto F, Ogawa T, Mammoto T, Hirano A.

J Rural Med. 2018 Nov;13(2):105-109. doi: 10.2185/jrm.2967. Epub 2018 Nov 29.


Charcot spinal arthropathy presenting as adjacent segment disease after lumbar spinal fusion surgery in Parkinson's disease: A case report.

Miura K, Koda M, Tatsumura M, Shiina I, Mammoto T, Hirano A, Abe T, Funayama T, Noguchi H, Yamazaki M.

J Clin Neurosci. 2019 Mar;61:281-284. doi: 10.1016/j.jocn.2018.11.013. Epub 2018 Nov 13.


Endothelial YAP1 in Regenerative Lung Growth through the Angiopoietin-Tie2 Pathway.

Mammoto T, Muyleart M, Mammoto A.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):117-127. doi: 10.1165/rcmb.2018-0105OC.


Arthroscopic treatment of intra-articular dysplasia epiphysealis hemimelica of the knee.

Mammoto T, Hirano A.

SAGE Open Med Case Rep. 2018 Jul 26;6:2050313X18790166. doi: 10.1177/2050313X18790166. eCollection 2018.


Arthroscopic synovectomy for the treatment of stage II to IV trapeziometacarpal joint arthritis.

Ogawa T, Tanaka T, Asakawa S, Tatsumura M, Mammoto T, Hirano A.

J Rural Med. 2018 May;13(1):76-81. doi: 10.2185/jrm.2962. Epub 2018 May 29.


YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α.

Mammoto A, Muyleart M, Kadlec A, Gutterman D, Mammoto T.

Microvasc Res. 2018 Sep;119:73-83. doi: 10.1016/j.mvr.2018.04.003. Epub 2018 Apr 20.


Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip.

Jalili-Firoozinezhad S, Prantil-Baun R, Jiang A, Potla R, Mammoto T, Weaver JC, Ferrante TC, Kim HJ, Cabral JMS, Levy O, Ingber DE.

Cell Death Dis. 2018 Feb 14;9(2):223. doi: 10.1038/s41419-018-0304-8.


Resolvins suppress tumor growth and enhance cancer therapy.

Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S, Panigrahy D.

J Exp Med. 2018 Jan 2;215(1):115-140. doi: 10.1084/jem.20170681. Epub 2017 Nov 30.


Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip.

Musah S, Mammoto A, Ferrante TC, Jeanty SSF, Hirano-Kobayashi M, Mammoto T, Roberts K, Chung S, Novak R, Ingram M, Fatanat-Didar T, Koshy S, Weaver JC, Church GM, Ingber DE.

Nat Biomed Eng. 2017;1. pii: 0069. doi: 10.1038/s41551-017-0069. Epub 2017 May 10.


Twist1 in Hypoxia-induced Pulmonary Hypertension through Transforming Growth Factor-β-Smad Signaling.

Mammoto T, Muyleart M, Konduri GG, Mammoto A.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):194-207. doi: 10.1165/rcmb.2016-0323OC.


Mechanical induction of dentin-like differentiation by adult mouse bone marrow stromal cells using compressive scaffolds.

Hashmi B, Mammoto T, Weaver J, Ferrante T, Jiang A, Jiang E, Feliz J, Ingber DE.

Stem Cell Res. 2017 Oct;24:55-60. doi: 10.1016/j.scr.2017.08.011. Epub 2017 Aug 17.


Proximal Femoral Fracture in Hip Arthrodesis Treated with Double Reconstruction Plates.

Asakawa S, Mammoto T, Hirano A.

Case Rep Orthop. 2017;2017:5246080. doi: 10.1155/2017/5246080. Epub 2017 Jun 11.


Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery.

Papa AL, Korin N, Kanapathipillai M, Mammoto A, Mammoto T, Jiang A, Mannix R, Uzun O, Johnson C, Bhatta D, Cuneo G, Ingber DE.

Biomaterials. 2017 Sep;139:187-194. doi: 10.1016/j.biomaterials.2017.06.003. Epub 2017 Jun 6.


Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics.

Jain A, Barrile R, van der Meer AD, Mammoto A, Mammoto T, De Ceunynck K, Aisiku O, Otieno MA, Louden CS, Hamilton GA, Flaumenhaft R, Ingber DE.

Clin Pharmacol Ther. 2018 Feb;103(2):332-340. doi: 10.1002/cpt.742. Epub 2017 Jul 14.


Role of Twist1 Phosphorylation in Angiogenesis and Pulmonary Fibrosis.

Mammoto T, Jiang A, Jiang E, Mammoto A.

Am J Respir Cell Mol Biol. 2016 Nov;55(5):633-644.


Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip.

Torisawa YS, Mammoto T, Jiang E, Jiang A, Mammoto A, Watters AL, Bahinski A, Ingber DE.

Tissue Eng Part C Methods. 2016 May;22(5):509-15. doi: 10.1089/ten.TEC.2015.0507. Epub 2016 Apr 20.


Effects of postoperative administration of celecoxib on pain management in patients after total knee arthroplasty: study protocol for an open-label randomized controlled trial.

Mammoto T, Fujie K, Mamizuka N, Taguchi N, Hirano A, Yamazaki M, Ueno S, Ma E, Hashimoto K.

Trials. 2016 Jan 23;17:45. doi: 10.1186/s13063-015-1106-2.


Improved treatment of systemic blood infections using antibiotics with extracorporeal opsonin hemoadsorption.

Didar TF, Cartwright MJ, Rottman M, Graveline AR, Gamini N, Watters AL, Leslie DC, Mammoto T, Rodas MJ, Kang JH, Waterhouse A, Seiler BT, Lombardo P, Qendro EI, Super M, Ingber DE.

Biomaterials. 2015 Oct;67:382-92. doi: 10.1016/j.biomaterials.2015.07.046. Epub 2015 Jul 26.


Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway.

Mammoto T, Chen Z, Jiang A, Jiang E, Ingber DE, Mammoto A.

Am J Respir Cell Mol Biol. 2016 Jan;54(1):103-13. doi: 10.1165/rcmb.2015-0045OC.


Mesenchymal condensation-dependent accumulation of collagen VI stabilizes organ-specific cell fates during embryonic tooth formation.

Mammoto T, Mammoto A, Jiang A, Jiang E, Hashmi B, Ingber DE.

Dev Dyn. 2015 Jun;244(6):713-23. doi: 10.1002/dvdy.24264. Epub 2015 Apr 24.


Implantation of fibrin gel on mouse lung to study lung-specific angiogenesis.

Mammoto T, Mammoto A.

J Vis Exp. 2014 Dec 21;(94). doi: 10.3791/52012.


An extracorporeal blood-cleansing device for sepsis therapy.

Kang JH, Super M, Yung CW, Cooper RM, Domansky K, Graveline AR, Mammoto T, Berthet JB, Tobin H, Cartwright MJ, Watters AL, Rottman M, Waterhouse A, Mammoto A, Gamini N, Rodas MJ, Kole A, Jiang A, Valentin TM, Diaz A, Takahashi K, Ingber DE.

Nat Med. 2014 Oct;20(10):1211-6. doi: 10.1038/nm.3640. Epub 2014 Sep 14.


Recovery from paraplegia with administration of erlotinib in a patient with lung adenocarcinoma.

Kurishima K, Kagohashi K, Mammoto T, Satoh H.

Contemp Oncol (Pozn). 2014;18(2):140-2. doi: 10.5114/wo.2014.41393. Epub 2014 Jun 3. No abstract available.


Platelet-rich plasma extract prevents pulmonary edema through angiopoietin-Tie2 signaling.

Mammoto T, Jiang A, Jiang E, Mammoto A.

Am J Respir Cell Mol Biol. 2015 Jan;52(1):56-64. doi: 10.1165/rcmb.2014-0076OC.


Vascular structure and function in the medial collateral ligament of anterior cruciate ligament transected rabbit knees.

Miller D, DeSutter C, Scott A, Koglin L, Hart DA, Salo P, Leonard C, Mammoto T, Bray RC.

J Orthop Res. 2014 Sep;32(9):1104-10. doi: 10.1002/jor.22643. Epub 2014 Jun 7.


RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity.

Kawasaki J, Aegerter S, Fevurly RD, Mammoto A, Mammoto T, Sahin M, Mably JD, Fishman SJ, Chan J.

J Clin Invest. 2014 Jun;124(6):2774-84. doi: 10.1172/JCI67084. Epub 2014 May 16.


Tibia metastasis from small cell lung cancer.

Kurishima K, Kagohashi K, Mammoto T, Satoh H.

Tuberk Toraks. 2014;62(1):89-90. No abstract available.


Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro.

Torisawa YS, Spina CS, Mammoto T, Mammoto A, Weaver JC, Tat T, Collins JJ, Ingber DE.

Nat Methods. 2014 Jun;11(6):663-9. doi: 10.1038/nmeth.2938. Epub 2014 May 4.


Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation.

Hashmi B, Zarzar LD, Mammoto T, Mammoto A, Jiang A, Aizenberg J, Ingber DE.

Adv Mater. 2014 May 28;26(20):3253-7. doi: 10.1002/adma.201304995. Epub 2014 Feb 18.


Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression.

German AE, Mammoto T, Jiang E, Ingber DE, Mammoto A.

J Cell Sci. 2014 Apr 15;127(Pt 8):1672-83. doi: 10.1242/jcs.132316. Epub 2014 Feb 12.


Quantifying cell-generated mechanical forces within living embryonic tissues.

Campàs O, Mammoto T, Hasso S, Sperling RA, O'Connell D, Bischof AG, Maas R, Weitz DA, Mahadevan L, Ingber DE.

Nat Methods. 2014 Feb;11(2):183-9. doi: 10.1038/nmeth.2761. Epub 2013 Dec 8. Erratum in: Nat Methods. 2014 Mar;11(3):349.


Mechanobiology and developmental control.

Mammoto T, Mammoto A, Ingber DE.

Annu Rev Cell Dev Biol. 2013;29:27-61. doi: 10.1146/annurev-cellbio-101512-122340. Review.


Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression.

Mammoto T, Jiang E, Jiang A, Lu Y, Juan AM, Chen J, Mammoto A.

PLoS One. 2013 Sep 2;8(9):e73407. doi: 10.1371/journal.pone.0073407. eCollection 2013.


Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression.

Mammoto T, Jiang A, Jiang E, Panigrahy D, Kieran MW, Mammoto A.

Am J Pathol. 2013 Oct;183(4):1293-1305. doi: 10.1016/j.ajpath.2013.06.026. Epub 2013 Aug 5.


Epoxyeicosanoids promote organ and tissue regeneration.

Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13528-33. doi: 10.1073/pnas.1311565110. Epub 2013 Jul 29.


Extracellular matrix structure and tissue stiffness control postnatal lung development through the lipoprotein receptor-related protein 5/Tie2 signaling system.

Mammoto T, Jiang E, Jiang A, Mammoto A.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):1009-18. doi: 10.1165/rcmb.2013-0147OC.


Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan.

Bischof AG, Yüksel D, Mammoto T, Mammoto A, Krause S, Ingber DE.

Integr Biol (Camb). 2013 Aug;5(8):1045-56. doi: 10.1039/c3ib40103k.


Platelet rich plasma extract promotes angiogenesis through the angiopoietin1-Tie2 pathway.

Mammoto T, Jiang A, Jiang E, Mammoto A.

Microvasc Res. 2013 Sep;89:15-24. doi: 10.1016/j.mvr.2013.04.008. Epub 2013 May 6.


Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics.

Mammoto A, Mammoto T, Kanapathipillai M, Wing Yung C, Jiang E, Jiang A, Lofgren K, Gee EP, Ingber DE.

Nat Commun. 2013;4:1759. doi: 10.1038/ncomms2774.


LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway.

Mammoto T, Chen J, Jiang E, Jiang A, Smith LE, Ingber DE, Mammoto A.

PLoS One. 2012;7(7):e41596. doi: 10.1371/journal.pone.0041596. Epub 2012 Jul 25.


Mechanosensitive mechanisms in transcriptional regulation.

Mammoto A, Mammoto T, Ingber DE.

J Cell Sci. 2012 Jul 1;125(Pt 13):3061-73. doi: 10.1242/jcs.093005. Epub 2012 Jul 13. Review.


Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels.

Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE.

Science. 2012 Aug 10;337(6095):738-42. doi: 10.1126/science.1217815. Epub 2012 Jul 5. Erratum in: Science. 2012 Sep 21;337(6101):1453.


High-resolution axial MR imaging of tibial stress injuries.

Mammoto T, Hirano A, Tomaru Y, Kono M, Tsukagoshi Y, Onishi S, Mamizuka N.

Sports Med Arthrosc Rehabil Ther Technol. 2012 May 10;4(1):16. doi: 10.1186/1758-2555-4-16.


Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix.

Kanapathipillai M, Mammoto A, Mammoto T, Kang JH, Jiang E, Ghosh K, Korin N, Gibbs A, Mannix R, Ingber DE.

Nano Lett. 2012 Jun 13;12(6):3213-7. doi: 10.1021/nl301206p. Epub 2012 May 10.


A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis.

O'Connell DJ, Ho JW, Mammoto T, Turbe-Doan A, O'Connell JT, Haseley PS, Koo S, Kamiya N, Ingber DE, Park PJ, Maas RL.

Sci Signal. 2012 Jan 10;5(206):ra4. doi: 10.1126/scisignal.2002414.


Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice.

Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC.

J Clin Invest. 2012 Jan;122(1):178-91. doi: 10.1172/JCI58128. Epub 2011 Dec 19.


Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation.

Mammoto T, Mammoto A, Torisawa YS, Tat T, Gibbs A, Derda R, Mannix R, de Bruijn M, Yung CW, Huh D, Ingber DE.

Dev Cell. 2011 Oct 18;21(4):758-69. doi: 10.1016/j.devcel.2011.07.006. Epub 2011 Sep 15.

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