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Items: 48


Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing.

Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN.

Sci Adv. 2018 Jan 31;4(1):eaap9004. doi: 10.1126/sciadv.aap9004. eCollection 2018 Jan.


Induction regimen and survival in simultaneous heart-kidney transplant recipients.

Ariyamuthu VK, Amin AA, Drazner MH, Araj F, Mammen PPA, Ayvaci M, Mete M, Ozay F, Ghanta M, Mohan S, Mohan P, Tanriover B.

J Heart Lung Transplant. 2018 May;37(5):587-595. doi: 10.1016/j.healun.2017.11.012. Epub 2017 Nov 15.


Predictors of Death in Adults With Duchenne Muscular Dystrophy-Associated Cardiomyopathy.

Cheeran D, Khan S, Khera R, Bhatt A, Garg S, Grodin JL, Morlend R, Araj FG, Amin AA, Thibodeau JT, Das S, Drazner MH, Mammen PPA.

J Am Heart Assoc. 2017 Oct 17;6(10). pii: e006340. doi: 10.1161/JAHA.117.006340.


Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients With Myotonic Dystrophy.

Mootha VV, Hansen B, Rong Z, Mammen PP, Zhou Z, Xing C, Gong X.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4579-4585. doi: 10.1167/iovs.17-22350.


Implantation of a left ventricular assist device to provide long-term support for end-stage Duchenne muscular dystrophy-associated cardiomyopathy.

Stoller D, Araj F, Amin A, Fitzsimmons C, Morlend R, Thibodeau JT, Ramaciotti C, Drazner MH, Meyer DM, Mammen PPA.

ESC Heart Fail. 2017 Aug;4(3):379-383. doi: 10.1002/ehf2.12160. Epub 2017 May 11.


Circulating microRNAs: Potential Markers of Cardiotoxicity in Children and Young Adults Treated With Anthracycline Chemotherapy.

Leger KJ, Leonard D, Nielson D, de Lemos JA, Mammen PP, Winick NJ.

J Am Heart Assoc. 2017 Apr 4;6(4). pii: e004653. doi: 10.1161/JAHA.116.004653.


Bendopnea and risk of adverse clinical outcomes in ambulatory patients with systolic heart failure.

Thibodeau JT, Jenny BE, Maduka JO, Divanji PH, Ayers CR, Araj F, Amin AA, Morlend RM, Mammen PP, Drazner MH.

Am Heart J. 2017 Jan;183:102-107. doi: 10.1016/j.ahj.2016.09.011. Epub 2016 Oct 2.


Human ventricular unloading induces cardiomyocyte proliferation.

Canseco DC, Kimura W, Garg S, Mukherjee S, Bhattacharya S, Abdisalaam S, Das S, Asaithamby A, Mammen PP, Sadek HA.

J Am Coll Cardiol. 2015 Mar 10;65(9):892-900. doi: 10.1016/j.jacc.2014.12.027. Epub 2015 Jan 21.


Variation of heart transplant rates in the United States during holidays.

Grodin JL, Ayers CR, Thibodeau JT, Mishkin JD, Mammen PP, Markham DW, Drazner MH, Patel PC.

Clin Transplant. 2014 Aug;28(8):877-82. doi: 10.1111/ctr.12396. Epub 2014 Jul 11.


High-sensitivity cardiac troponin I assay to screen for acute rejection in patients with heart transplant.

Patel PC, Hill DA, Ayers CR, Lavingia B, Kaiser P, Dyer AK, Barnes AP, Thibodeau JT, Mishkin JD, Mammen PP, Markham DW, Stastny P, Ring WS, de Lemos JA, Drazner MH.

Circ Heart Fail. 2014 May;7(3):463-9. doi: 10.1161/CIRCHEARTFAILURE.113.000697. Epub 2014 Apr 14.


Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway.

Wang ZV, Deng Y, Gao N, Pedrozo Z, Li DL, Morales CR, Criollo A, Luo X, Tan W, Jiang N, Lehrman MA, Rothermel BA, Lee AH, Lavandero S, Mammen PPA, Ferdous A, Gillette TG, Scherer PE, Hill JA.

Cell. 2014 Mar 13;156(6):1179-1192. doi: 10.1016/j.cell.2014.01.014.


Characterization of a novel symptom of advanced heart failure: bendopnea.

Thibodeau JT, Turer AT, Gualano SK, Ayers CR, Velez-Martinez M, Mishkin JD, Patel PC, Mammen PP, Markham DW, Levine BD, Drazner MH.

JACC Heart Fail. 2014 Feb;2(1):24-31. doi: 10.1016/j.jchf.2013.07.009. Epub 2014 Jan 8.


Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration.

Singh S, Canseco DC, Manda SM, Shelton JM, Chirumamilla RR, Goetsch SC, Ye Q, Gerard RD, Schneider JW, Richardson JA, Rothermel BA, Mammen PP.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E129-38. doi: 10.1073/pnas.1314962111. Epub 2013 Dec 23.


Tolerability of sirolimus: a decade of experience at a single cardiac transplant center.

Thibodeau JT, Mishkin JD, Patel PC, Kaiser PA, Ayers CR, Mammen PP, Markham DW, Ring WS, Peltz M, Drazner MH.

Clin Transplant. 2013 Nov-Dec;27(6):945-52. doi: 10.1111/ctr.12269. Epub 2013 Oct 30.


Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease.

Hunt JM, Bethea B, Liu X, Gandjeva A, Mammen PP, Stacher E, Gandjeva MR, Parish E, Perez M, Smith L, Graham BB, Kuebler WM, Tuder RM.

Am J Physiol Lung Cell Mol Physiol. 2013 Nov 15;305(10):L725-36. doi: 10.1152/ajplung.00186.2013. Epub 2013 Sep 13.


Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.

Quintens R, Singh S, Lemaire K, De Bock K, Granvik M, Schraenen A, Vroegrijk IO, Costa V, Van Noten P, Lambrechts D, Lehnert S, Van Lommel L, Thorrez L, De Faudeur G, Romijn JA, Shelton JM, Scorrano L, Lijnen HR, Voshol PJ, Carmeliet P, Mammen PP, Schuit F.

PLoS One. 2013;8(2):e56719. doi: 10.1371/journal.pone.0056719. Epub 2013 Feb 27.


Relationship of right- to left-sided ventricular filling pressures in advanced heart failure: insights from the ESCAPE trial.

Drazner MH, Velez-Martinez M, Ayers CR, Reimold SC, Thibodeau JT, Mishkin JD, Mammen PP, Markham DW, Patel CB.

Circ Heart Fail. 2013 Mar;6(2):264-70. doi: 10.1161/CIRCHEARTFAILURE.112.000204. Epub 2013 Feb 7.


Health insurance as a requirement to undergo cardiac transplantation: a national survey of transplant program practices.

Thibodeau JT, Rao MP, Gupta C, Ayers CR, Gupta S, Mammen PP, Markham DW, Mishkin JD, Patel PC, King LP, Drazner MH.

Transplant Proc. 2013 Jan-Feb;45(1):360-3. doi: 10.1016/j.transproceed.2012.05.074. Epub 2012 Sep 6.


Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.

Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HA.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):187-92. doi: 10.1073/pnas.1208863110. Epub 2012 Dec 17.


The natural history of new-onset heart failure with a severely depressed left ventricular ejection fraction: implications for timing of implantable cardioverter-defibrillator implantation.

Teeter WA, Thibodeau JT, Rao K, Brickner ME, Toto KH, Nelson LL, Mishkin JD, Ayers CR, Miller JG, Mammen PP, Patel PC, Markham DW, Drazner MH.

Am Heart J. 2012 Sep;164(3):358-64. doi: 10.1016/j.ahj.2012.06.009.


Sirolimus use and incidence of venous thromboembolism in cardiac transplant recipients.

Thibodeau JT, Mishkin JD, Patel PC, Kaiser PA, Ayers CR, Mammen PP, Markham DW, Ring WS, Peltz M, Drazner MH.

Clin Transplant. 2012 Nov-Dec;26(6):953-9. doi: 10.1111/j.1399-0012.2012.01677.x. Epub 2012 Jul 9.


IIIB or not IIIB: a previously unanswered question.

Thibodeau JT, Mishkin JD, Patel PC, Mammen PP, Markham DW, Drazner MH.

J Card Fail. 2012 May;18(5):367-72. doi: 10.1016/j.cardfail.2012.01.016. Epub 2012 Mar 8.


Utilization of cardiac computed tomography angiography for the diagnosis of left ventricular assist device thrombosis.

Mishkin JD, Enriquez JR, Meyer DM, Bethea BT, Thibodeau JT, Patel PC, Markham DW, Mammen PP, Velez-Martinez M, Drazner MH.

Circ Heart Fail. 2012 Mar 1;5(2):e27-9. doi: 10.1161/CIRCHEARTFAILURE.111.966119. No abstract available.


Successful use of the TandemHeart percutaneous ventricular assist device as a bridge to recovery for acute cellular rejection in a cardiac transplant patient.

Velez-Martinez M, Rao K, Warner J, Dimaio J, Ewing G, Mishkin JD, Mammen PP, Drazner MH, Markham DW, Patel PC.

Transplant Proc. 2011 Dec;43(10):3882-4. doi: 10.1016/j.transproceed.2011.09.080.


Regulation of myoglobin expression.

Kanatous SB, Mammen PP.

J Exp Biol. 2010 Aug 15;213(Pt 16):2741-7. doi: 10.1242/jeb.041442. Review.


Concentric left ventricular hypertrophy as assessed by cardiac magnetic resonance imaging and risk of death in cardiac transplant recipients.

Patel PC, Reimold SC, Araj FG, Ayers CR, Kaiser PA, Peshock RM, Yancy CW, Ring WS, Gupta S, Mishkin JD, Mammen PP, Markham DW, Drazner MH.

J Heart Lung Transplant. 2010 Dec;29(12):1369-79. doi: 10.1016/j.healun.2010.05.008.


Clinical outcomes after cardiac transplantation in muscular dystrophy patients.

Wu RS, Gupta S, Brown RN, Yancy CW, Wald JW, Kaiser P, Kirklin NM, Patel PC, Markham DW, Drazner MH, Garry DJ, Mammen PP.

J Heart Lung Transplant. 2010 Apr;29(4):432-8. doi: 10.1016/j.healun.2009.08.030. Epub 2009 Oct 28.


Association of cystatin C with left ventricular structure and function: the Dallas Heart Study.

Patel PC, Ayers CR, Murphy SA, Peshock R, Khera A, de Lemos JA, Balko JA, Gupta S, Mammen PP, Drazner MH, Markham DW.

Circ Heart Fail. 2009 Mar;2(2):98-104. doi: 10.1161/CIRCHEARTFAILURE.108.807271. Epub 2009 Feb 10.


Pancreatic gout masquerading as pancreatic cancer in a heart transplant candidate.

Gupta S, McMahan Z, Patel PC, Markham DW, Drazner MH, Mammen PP.

J Heart Lung Transplant. 2009 Oct;28(10):1112-3. doi: 10.1016/j.healun.2009.05.039.


Utility of routine immunofluorescence staining for C4d in cardiac transplant recipients.

Gupta S, Mitchell JD, Lavingia B, Ewing GE, Feliciano MN, Kaiser PA, Ring WS, Stastny P, Patel PC, Markham DW, Mammen PP, Dimaio JM, Drazner MH.

J Heart Lung Transplant. 2009 Aug;28(8):776-80. doi: 10.1016/j.healun.2009.05.007. Erratum in: J Heart Lung Transplant. 2009 Sep;28(9):987..


Calcineurin activates cytoglobin transcription in hypoxic myocytes.

Singh S, Manda SM, Sikder D, Birrer MJ, Rothermel BA, Garry DJ, Mammen PP.

J Biol Chem. 2009 Apr 17;284(16):10409-21. doi: 10.1074/jbc.M809572200. Epub 2009 Feb 9.


Hypoxia reprograms calcium signaling and regulates myoglobin expression.

Kanatous SB, Mammen PP, Rosenberg PB, Martin CM, White MD, Dimaio JM, Huang G, Muallem S, Garry DJ.

Am J Physiol Cell Physiol. 2009 Mar;296(3):C393-402. doi: 10.1152/ajpcell.00428.2008. Epub 2008 Nov 12.


Fulminant myocarditis.

Gupta S, Markham DW, Drazner MH, Mammen PP.

Nat Clin Pract Cardiovasc Med. 2008 Nov;5(11):693-706. doi: 10.1038/ncpcardio1331. Epub 2008 Sep 16. Review.


Utility of the Cylex assay in cardiac transplant recipients.

Gupta S, Mitchell JD, Markham DW, Mammen PP, Patel PC, Kaiser PA, Stastny P, Ring WS, Dimaio JM, Drazner MH.

J Heart Lung Transplant. 2008 Aug;27(8):817-22. doi: 10.1016/j.healun.2008.05.014. Epub 2008 Jun 30.


High incidence of cytomegalovirus disease in D+/R- heart transplant recipients shortly after completion of 3 months of valganciclovir prophylaxis.

Gupta S, Mitchell JD, Markham DW, Mammen PP, Patel PC, Kaiser P, Ring WS, DiMaio JM, Drazner MH.

J Heart Lung Transplant. 2008 May;27(5):536-9. doi: 10.1016/j.healun.2008.02.002.


Long-term follow-up of a heart transplant recipient with documented seroconversion to HIV-positive status 1 year after transplant.

Gupta S, Markham DW, Mammen PP, Kaiser P, Patel P, Ring WS, Drazner MH.

Am J Transplant. 2008 Apr;8(4):893-6. doi: 10.1111/j.1600-6143.2008.02154.x. Epub 2008 Feb 19.


Molecular insights into the functional role of myoglobin.

Garry DJ, Mammen PP.

Adv Exp Med Biol. 2007;618:181-93. Review.


Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain.

Mammen PP, Shelton JM, Ye Q, Kanatous SB, McGrath AJ, Richardson JA, Garry DJ.

J Histochem Cytochem. 2006 Dec;54(12):1349-61. Epub 2006 Aug 9.


Alternative therapies for orthotopic heart transplantation.

Garry DJ, Goetsch SC, McGrath AJ, Mammen PP.

Am J Med Sci. 2005 Aug;330(2):88-101. Review. Erratum in: Am J Med Sci. 2005 Sep;330(3):119.


LXRs regulate the balance between fat storage and oxidation.

Kalaany NY, Gauthier KC, Zavacki AM, Mammen PP, Kitazume T, Peterson JA, Horton JD, Garry DJ, Bianco AC, Mangelsdorf DJ.

Cell Metab. 2005 Apr;1(4):231-44.


The capsaicin-sensitive afferent neuron in skeletal muscle is abnormal in heart failure.

Smith SA, Williams MA, Mitchell JH, Mammen PP, Garry MG.

Circulation. 2005 Apr 26;111(16):2056-65.


Role of the exercise pressor reflex in rats with dilated cardiomyopathy.

Smith SA, Mammen PP, Mitchell JH, Garry MG.

Circulation. 2003 Sep 2;108(9):1126-32. Epub 2003 Aug 18.


Neuroprotection and the role of neuroglobin.

Garry DJ, Mammen PP.

Lancet. 2003 Aug 2;362(9381):342-3. No abstract available.


Hypoxia-induced left ventricular dysfunction in myoglobin-deficient mice.

Mammen PP, Kanatous SB, Yuhanna IS, Shaul PW, Garry MG, Balaban RS, Garry DJ.

Am J Physiol Heart Circ Physiol. 2003 Nov;285(5):H2132-41. Epub 2003 Jul 24.


Emerging roles for myoglobin in the heart.

Garry DJ, Kanatous SB, Mammen PP.

Trends Cardiovasc Med. 2003 Apr;13(3):111-6. Review.


Neuroglobin, a novel member of the globin family, is expressed in focal regions of the brain.

Mammen PP, Shelton JM, Goetsch SC, Williams SC, Richardson JA, Garry MG, Garry DJ.

J Histochem Cytochem. 2002 Dec;50(12):1591-8.


Adaptive mechanisms that preserve cardiac function in mice without myoglobin.

Meeson AP, Radford N, Shelton JM, Mammen PP, DiMaio JM, Hutcheson K, Kong Y, Elterman J, Williams RS, Garry DJ.

Circ Res. 2001 Apr 13;88(7):713-20.


Isometric and dynamic contractile properties of porcine skinned cardiac myocytes after stunning.

McDonald KS, Mammen PP, Strang KT, Moss RL, Miller WP.

Circ Res. 1995 Nov;77(5):964-72.

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