Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 183

1.

p38γ is essential for cell cycle progression and liver tumorigenesis.

Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G.

Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10.

PMID:
30971822
2.

Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma.

López-Nieva P, Fernández-Navarro P, Graña-Castro O, Andrés-León E, Santos J, Villa-Morales M, Cobos-Fernández MÁ, González-Sánchez L, Malumbres M, Salazar-Roa M, Fernández-Piqueras J.

Sci Rep. 2019 Mar 26;9(1):5179. doi: 10.1038/s41598-019-41675-3.

3.

Aurora A controls CD8+ T cell cytotoxic activity and antiviral response.

Bustos-Morán E, Blas-Rus N, Alcaraz-Serna A, Iborra S, González-Martínez J, Malumbres M, Sánchez-Madrid F.

Sci Rep. 2019 Feb 18;9(1):2211. doi: 10.1038/s41598-019-38647-y.

4.

Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma.

Vázquez-Domínguez I, González-Sánchez L, López-Nieva P, Fernández-Navarro P, Villa-Morales M, Cobos-Fernández MÁ, Sastre I, F Fraga M, F Fernández A, Malumbres M, Salazar-Roa M, Graña-Castro O, Santos J, Llamas P, López-Lorenzo JL, Fernández-Piqueras J.

Oncogene. 2019 Jun;38(23):4620-4636. doi: 10.1038/s41388-019-0746-1. Epub 2019 Feb 11.

PMID:
30742097
5.

Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells.

Rata S, Suarez Peredo Rodriguez MF, Joseph S, Peter N, Echegaray Iturra F, Yang F, Madzvamuse A, Ruppert JG, Samejima K, Platani M, Alvarez-Fernandez M, Malumbres M, Earnshaw WC, Novak B, Hochegger H.

Curr Biol. 2018 Dec 3;28(23):3824-3832.e6. doi: 10.1016/j.cub.2018.09.059. Epub 2018 Nov 15.

6.

Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis.

Nguyen AL, Drutovic D, Vazquez BN, El Yakoubi W, Gentilello AS, Malumbres M, Solc P, Schindler K.

Curr Biol. 2018 Nov 5;28(21):3458-3468.e5. doi: 10.1016/j.cub.2018.08.052. Epub 2018 Oct 25.

PMID:
30415701
7.

Error Resilient Coding Techniques for Video Delivery over Vehicular Networks.

Piñol P, Martinez-Rach M, Garrido P, Lopez-Granado O, Malumbres MP.

Sensors (Basel). 2018 Oct 17;18(10). pii: E3495. doi: 10.3390/s18103495.

8.

Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets.

Hurtado B, Trakala M, Ximénez-Embún P, El Bakkali A, Partida D, Sanz-Castillo B, Álvarez-Fernández M, Maroto M, Sánchez-Martínez R, Martínez L, Muñoz J, García de Frutos P, Malumbres M.

J Clin Invest. 2018 Dec 3;128(12):5351-5367. doi: 10.1172/JCI121876. Epub 2018 Oct 29.

9.

Source Coding Options to Improve HEVC Video Streaming in Vehicular Networks.

Abenza PPG, Malumbres MP, Piñol P, López-Granado O.

Sensors (Basel). 2018 Sep 14;18(9). pii: E3107. doi: 10.3390/s18093107.

10.

CDK4/6 Inhibitors: What Is the Best Cocktail?

Malumbres M.

Clin Cancer Res. 2019 Jan 1;25(1):6-8. doi: 10.1158/1078-0432.CCR-18-2177. Epub 2018 Aug 16.

PMID:
30115629
11.

Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1.

Ovejero S, Ayala P, Malumbres M, Pimentel-Muiños FX, Bueno A, Sacristán MP.

Sci Rep. 2018 Aug 8;8(1):11871. doi: 10.1038/s41598-018-30253-8.

12.

Plk1 overexpression induces chromosomal instability and suppresses tumor development.

de Cárcer G, Venkateswaran SV, Salgueiro L, El Bakkali A, Somogyi K, Rowald K, Montañés P, Sanclemente M, Escobar B, de Martino A, McGranahan N, Malumbres M, Sotillo R.

Nat Commun. 2018 Aug 1;9(1):3012. doi: 10.1038/s41467-018-05429-5.

13.

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.

Bellutti F, Tigan AS, Nebenfuehr S, Dolezal M, Zojer M, Grausenburger R, Hartenberger S, Kollmann S, Doma E, Prchal-Murphy M, Uras IZ, Höllein A, Neuberg DS, Ebert BL, Ringler A, Mueller AC, Loizou JI, Hinds PW, Vogl C, Heller G, Kubicek S, Zuber J, Malumbres M, Farlik M, Villunger A, Kollmann K, Sexl V.

Cancer Discov. 2018 Jul;8(7):884-897. doi: 10.1158/2159-8290.CD-17-0912. Epub 2018 Jun 13.

14.

RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas.

López-Nieva P, Fernández-Navarro P, Vaquero-Lorenzo C, Villa-Morales M, Graña-Castro O, Cobos-Fernández MÁ, López-Lorenzo JL, Llamas P, González-Sanchez L, Sastre I, Pollan M, Malumbres M, Santos J, Fernández-Piqueras J.

BMC Cancer. 2018 Apr 16;18(1):430. doi: 10.1186/s12885-018-4304-y.

15.

An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability.

Mitxelena J, Apraiz A, Vallejo-Rodríguez J, García-Santisteban I, Fullaondo A, Alvarez-Fernández M, Malumbres M, Zubiaga AM.

Nucleic Acids Res. 2018 May 18;46(9):4546-4559. doi: 10.1093/nar/gky218.

16.

Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer.

Álvarez-Fernández M, Sanz-Flores M, Sanz-Castillo B, Salazar-Roa M, Partida D, Zapatero-Solana E, Ali HR, Manchado E, Lowe S, VanArsdale T, Shields D, Caldas C, Quintela-Fandino M, Malumbres M.

Cell Death Differ. 2018 May;25(5):828-840. doi: 10.1038/s41418-017-0024-0. Epub 2017 Dec 11.

17.

Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.

de Cárcer G, Wachowicz P, Martínez-Martínez S, Oller J, Méndez-Barbero N, Escobar B, González-Loyola A, Takaki T, El Bakkali A, Cámara JA, Jiménez-Borreguero LJ, Bustelo XR, Cañamero M, Mulero F, de Los Ángeles Sevilla M, Montero MJ, Redondo JM, Malumbres M.

Nat Med. 2017 Aug;23(8):964-974. doi: 10.1038/nm.4364. Epub 2017 Jul 10.

PMID:
28692064
18.

SnapShot: Phosphoregulation of Mitosis.

Burgess A, Vuong J, Rogers S, Malumbres M, O'Donoghue SI.

Cell. 2017 Jun 15;169(7):1358-1358.e1. doi: 10.1016/j.cell.2017.06.003.

19.

The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.

Ha K, Ma C, Lin H, Tang L, Lian Z, Zhao F, Li JM, Zhen B, Pei H, Han S, Malumbres M, Jin J, Chen H, Zhao Y, Zhu Q, Zhang P.

Nat Commun. 2017 Jun 12;8:15751. doi: 10.1038/ncomms15751.

20.

APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity.

Rattani A, Ballesteros Mejia R, Roberts K, Roig MB, Godwin J, Hopkins M, Eguren M, Sanchez-Pulido L, Okaz E, Ogushi S, Wolna M, Metson J, Pendás AM, Malumbres M, Novák B, Herbert M, Nasmyth K.

Curr Biol. 2017 May 22;27(10):1462-1476.e5. doi: 10.1016/j.cub.2017.04.023. Epub 2017 May 11.

21.

Programmed mitophagy is essential for the glycolytic switch during cell differentiation.

Esteban-Martínez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Mariño G, Seco E, Durand S, Enot D, Graña O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P.

EMBO J. 2017 Jun 14;36(12):1688-1706. doi: 10.15252/embj.201695916. Epub 2017 May 2.

22.

Myelopathy secondary to copper deficiency: The great imitator.

Urtiaga S, Terrero R, Malumbres M, Pinel A.

Neurologia. 2018 May;33(4):278-281. doi: 10.1016/j.nrl.2017.02.009. Epub 2017 Apr 21. English, Spanish. No abstract available.

23.

Fueling the Cell Division Cycle.

Salazar-Roa M, Malumbres M.

Trends Cell Biol. 2017 Jan;27(1):69-81. doi: 10.1016/j.tcb.2016.08.009. Epub 2016 Oct 13. Review.

PMID:
27746095
24.

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis.

Kollmann K, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, Schäfer M, Fajmann S, Schlederer M, Schiefer AI, Reichart U, Mayerhofer M, Hoeller C, Zöchbauer-Müller S, Kerjaschki D, Bock C, Kenner L, Hoefler G, Freissmuth M, Green AR, Moriggl R, Busslinger M, Malumbres M, Sexl V.

Cancer Cell. 2016 Aug 8;30(2):359-360. doi: 10.1016/j.ccell.2016.07.003. Epub 2016 Aug 8. No abstract available.

25.

Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner.

Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, Malumbres M, Liu J, Zou W, Wei W.

Cell Discov. 2016 Feb 2;2:15044. doi: 10.1038/celldisc.2015.44. eCollection 2016.

26.

Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid.

Shao R, Liu J, Yan G, Zhang J, Han Y, Guo J, Xu Z, Yuan Z, Liu J, Malumbres M, Wan L, Wei W, Zou W.

Cell Res. 2016 Jun;26(6):699-712. doi: 10.1038/cr.2016.51. Epub 2016 Apr 29.

27.

Aurora A drives early signalling and vesicle dynamics during T-cell activation.

Blas-Rus N, Bustos-Morán E, Pérez de Castro I, de Cárcer G, Borroto A, Camafeita E, Jorge I, Vázquez J, Alarcón B, Malumbres M, Martín-Cófreces NB, Sánchez-Madrid F.

Nat Commun. 2016 Apr 19;7:11389. doi: 10.1038/ncomms11389.

28.

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression.

Bueno MJ, Pérez de Castro I, Gómez de Cedrón M, Santos J, Calin GA, Cigudosa JC, Croce CM, Fernández-Piqueras J, Malumbres M.

Cancer Cell. 2016 Apr 11;29(4):607-608. doi: 10.1016/j.ccell.2016.03.013. No abstract available.

29.

Design of a Computerised Flight Mill Device to Measure the Flight Potential of Different Insects.

Martí-Campoy A, Ávalos JA, Soto A, Rodríguez-Ballester F, Martínez-Blay V, Malumbres MP.

Sensors (Basel). 2016 Apr 7;16(4). pii: E485. doi: 10.3390/s16040485.

30.

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

Hydbring P, Malumbres M, Sicinski P.

Nat Rev Mol Cell Biol. 2016 May;17(5):280-92. doi: 10.1038/nrm.2016.27. Epub 2016 Apr 1. Review.

31.

CDK4/6 Inhibitors resTORe Therapeutic Sensitivity in HER²⁺ Breast Cancer.

Malumbres M.

Cancer Cell. 2016 Mar 14;29(3):243-244. doi: 10.1016/j.ccell.2016.02.016.

32.

E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation.

Mitxelena J, Apraiz A, Vallejo-Rodríguez J, Malumbres M, Zubiaga AM.

Nucleic Acids Res. 2016 Mar 9. pii: gkw146. [Epub ahead of print]

33.

The cell proliferation antigen Ki-67 organises heterochromatin.

Sobecki M, Mrouj K, Camasses A, Parisis N, Nicolas E, Llères D, Gerbe F, Prieto S, Krasinska L, David A, Eguren M, Birling MC, Urbach S, Hem S, Déjardin J, Malumbres M, Jay P, Dulic V, Lafontaine DLj, Feil R, Fisher D.

Elife. 2016 Mar 7;5:e13722. doi: 10.7554/eLife.13722.

34.

microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia.

Correia NC, Melão A, Póvoa V, Sarmento L, Gómez de Cedrón M, Malumbres M, Enguita FJ, Barata JT.

Oncotarget. 2016 Feb 16;7(7):8268-81. doi: 10.18632/oncotarget.6987.

35.

Deregulated expression of Cdc6 in the skin facilitates papilloma formation and affects the hair growth cycle.

Búa S, Sotiropoulou P, Sgarlata C, Borlado LR, Eguren M, Domínguez O, Ortega S, Malumbres M, Blanpain C, Méndez J.

Cell Cycle. 2015;14(24):3897-907. doi: 10.1080/15384101.2015.1120919.

36.

Keeping Order in Anaphase.

Malumbres M.

Dev Cell. 2015 Nov 23;35(4):403-4. doi: 10.1016/j.devcel.2015.11.011.

37.

Mitophagy in mitosis: More than a myth.

Esteban-Martínez L, Doménech E, Boya P, Salazar-Roa M, Malumbres M.

Autophagy. 2015;11(12):2379-80. doi: 10.1080/15548627.2015.1108509. Review. No abstract available.

38.

A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy.

Sánchez-Martínez R, Cruz-Gil S, Gómez de Cedrón M, Álvarez-Fernández M, Vargas T, Molina S, García B, Herranz J, Moreno-Rubio J, Reglero G, Pérez-Moreno M, Feliu J, Malumbres M, Ramírez de Molina A.

Oncotarget. 2015 Nov 17;6(36):38719-36. doi: 10.18632/oncotarget.5340.

39.

AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest.

Doménech E, Maestre C, Esteban-Martínez L, Partida D, Pascual R, Fernández-Miranda G, Seco E, Campos-Olivas R, Pérez M, Megias D, Allen K, López M, Saha AK, Velasco G, Rial E, Méndez R, Boya P, Salazar-Roa M, Malumbres M.

Nat Cell Biol. 2015 Oct;17(10):1304-16. doi: 10.1038/ncb3231. Epub 2015 Aug 31.

PMID:
26322680
40.

An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress.

Quereda V, Porlan E, Cañamero M, Dubus P, Malumbres M.

Cell Death Differ. 2016 Mar;23(3):430-41. doi: 10.1038/cdd.2015.112. Epub 2015 Aug 21.

41.

Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development.

González-Loyola A, Fernández-Miranda G, Trakala M, Partida D, Samejima K, Ogawa H, Cañamero M, de Martino A, Martínez-Ramírez Á, de Cárcer G, Pérez de Castro I, Earnshaw WC, Malumbres M.

Mol Cell Biol. 2015 Oct;35(20):3566-78. doi: 10.1128/MCB.01286-14. Epub 2015 Aug 3.

42.

PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.

Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, Pandolfi PP, Bigas A, Carracedo A, Gerhardt H, Graupera M.

Nat Commun. 2015 Jul 31;6:7935. doi: 10.1038/ncomms8935.

43.

Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice.

Trakala M, Partida D, Salazar-Roa M, Maroto M, Wachowicz P, de Cárcer G, Malumbres M.

Blood. 2015 Oct 1;126(14):1707-14. doi: 10.1182/blood-2015-03-634402. Epub 2015 Jul 16.

44.

An Atypical Oncogene Within the Atypical E2Fs.

Álvarez-Fernández M, Malumbres M.

J Natl Cancer Inst. 2015 Jun 18;107(9). pii: djv180. doi: 10.1093/jnci/djv180. Print 2015 Sep. No abstract available.

45.

A Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent Synaptic Plasticity in the Mammalian Brain.

Huang J, Ikeuchi Y, Malumbres M, Bonni A.

Neuron. 2015 May 6;86(3):726-39. doi: 10.1016/j.neuron.2015.03.049. Epub 2015 Apr 23.

46.

Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.

Penas C, Govek EE, Fang Y, Ramachandran V, Daniel M, Wang W, Maloof ME, Rahaim RJ, Bibian M, Kawauchi D, Finkelstein D, Han JL, Long J, Li B, Robbins DJ, Malumbres M, Roussel MF, Roush WR, Hatten ME, Ayad NG.

Cell Rep. 2015 Apr 14;11(2):249-60. doi: 10.1016/j.celrep.2015.03.016. Epub 2015 Apr 2.

47.

Functional reprogramming of polyploidization in megakaryocytes.

Trakala M, Rodríguez-Acebes S, Maroto M, Symonds CE, Santamaría D, Ortega S, Barbacid M, Méndez J, Malumbres M.

Dev Cell. 2015 Jan 26;32(2):155-67. doi: 10.1016/j.devcel.2014.12.015.

48.

Cyclin C surprises in tumour suppression.

Trakala M, Malumbres M.

Nat Cell Biol. 2014 Nov;16(11):1031-3. doi: 10.1038/ncb3055.

PMID:
25358351
49.

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.

Scheicher R, Hoelbl-Kovacic A, Bellutti F, Tigan AS, Prchal-Murphy M, Heller G, Schneckenleithner C, Salazar-Roa M, Zöchbauer-Müller S, Zuber J, Malumbres M, Kollmann K, Sexl V.

Blood. 2015 Jan 1;125(1):90-101. doi: 10.1182/blood-2014-06-584417. Epub 2014 Oct 23. Erratum in: Blood. 2018 Aug 30;132(9):978-979.

50.

Splicing together sister chromatids.

Valcárcel J, Malumbres M.

EMBO J. 2014 Nov 18;33(22):2601-3. doi: 10.15252/embj.201489988. Epub 2014 Sep 29.

Supplemental Content

Loading ...
Support Center