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Items: 20

1.

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.

Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W.

Cell Metab. 2018 May 1;27(5):977-987.e4. doi: 10.1016/j.cmet.2018.02.024. Epub 2018 Apr 5.

PMID:
29628419
2.

The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.

Huang L, Malu S, McKenzie JA, Andrews MC, Talukder AH, Tieu T, Karpinets T, Haymaker C, Forget MA, Williams LJ, Wang Z, Mbofung RM, Wang ZQ, Davis RE, Lo RS, Wargo JA, Davies MA, Bernatchez C, Heffernan T, Amaria RN, Korkut A, Peng W, Roszik J, Lizée G, Woodman SE, Hwu P.

Clin Cancer Res. 2018 Jul 15;24(14):3366-3376. doi: 10.1158/1078-0432.CCR-17-2483. Epub 2018 Mar 1.

PMID:
29496759
3.

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.

McKenzie JA, Mbofung RM, Malu S, Zhang M, Ashkin E, Devi S, Williams L, Tieu T, Peng W, Pradeep S, Xu C, Zorro Manrique S, Liu C, Huang L, Chen Y, Forget MA, Haymaker C, Bernatchez C, Satani N, Muller F, Roszik J, Kalra A, Heffernan T, Sood A, Hu J, Amaria R, Davis RE, Hwu P.

J Natl Cancer Inst. 2018 Jul 1;110(7):777-786. doi: 10.1093/jnci/djx257.

4.

Relativistic inverse Compton scattering of photons from the early universe.

Malu S, Datta A, Colafrancesco S, Marchegiani P, Subrahmanyan R, Narasimha D, Wieringa MH.

Sci Rep. 2017 Dec 5;7(1):16918. doi: 10.1038/s41598-017-17104-8.

5.

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.

Mbofung RM, McKenzie JA, Malu S, Zhang M, Peng W, Liu C, Kuiatse I, Tieu T, Williams L, Devi S, Ashkin E, Xu C, Huang L, Zhang M, Talukder AH, Tripathi SC, Khong H, Satani N, Muller FL, Roszik J, Heffernan T, Allison JP, Lizee G, Hanash SM, Proia D, Amaria R, Davis RE, Hwu P.

Nat Commun. 2017 Sep 6;8(1):451. doi: 10.1038/s41467-017-00449-z.

6.

A Novel Method to Generate and Expand Clinical-Grade, Genetically Modified, Tumor-Infiltrating Lymphocytes.

Forget MA, Tavera RJ, Haymaker C, Ramachandran R, Malu S, Zhang M, Wardell S, Fulbright OJ, Toth CL, Gonzalez AM, Thorsen ST, Flores E, Wahl A, Peng W, Amaria RN, Hwu P, Bernatchez C.

Front Immunol. 2017 Aug 2;8:908. doi: 10.3389/fimmu.2017.00908. eCollection 2017.

7.

High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth.

de Graaff MA, Malu S, Guardiola I, Kruisselbrink AB, de Jong Y, Corver WE, Gelderblom H, Hwu P, Nielsen TO, Lazar AJ, Somaiah N, Bovée JVMG.

Transl Oncol. 2017 Aug;10(4):546-554. doi: 10.1016/j.tranon.2017.05.007. Epub 2017 Jun 24.

8.

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL Jr, Bosenberg MW, Woodman SE, Overwijk WW, Lizée G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P.

Cancer Discov. 2016 Feb;6(2):202-16. doi: 10.1158/2159-8290.CD-15-0283. Epub 2015 Dec 8.

9.

Analysis of the intratumoral adaptive immune response in well differentiated and dedifferentiated retroperitoneal liposarcoma.

Tseng WW, Malu S, Zhang M, Chen J, Sim GC, Wei W, Ingram D, Somaiah N, Lev DC, Pollock RE, Lizée G, Radvanyi L, Hwu P.

Sarcoma. 2015;2015:547460. doi: 10.1155/2015/547460. Epub 2015 Jan 29.

10.

Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma.

Forget MA, Malu S, Liu H, Toth C, Maiti S, Kale C, Haymaker C, Bernatchez C, Huls H, Wang E, Marincola FM, Hwu P, Cooper LJ, Radvanyi LG.

J Immunother. 2014 Nov-Dec;37(9):448-60. doi: 10.1097/CJI.0000000000000056.

11.

DNA Ligase IV regulates XRCC4 nuclear localization.

Francis DB, Kozlov M, Chavez J, Chu J, Malu S, Hanna M, Cortes P.

DNA Repair (Amst). 2014 Sep;21:36-42. doi: 10.1016/j.dnarep.2014.05.010. Epub 2014 Jun 28.

12.

Structural basis of DNA ligase IV-Artemis interaction in nonhomologous end-joining.

De Ioannes P, Malu S, Cortes P, Aggarwal AK.

Cell Rep. 2012 Dec 27;2(6):1505-12. doi: 10.1016/j.celrep.2012.11.004. Epub 2012 Dec 7.

13.

Role of non-homologous end joining in V(D)J recombination.

Malu S, Malshetty V, Francis D, Cortes P.

Immunol Res. 2012 Dec;54(1-3):233-46. doi: 10.1007/s12026-012-8329-z. Review.

PMID:
22569912
14.

Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs.

Malu S, De Ioannes P, Kozlov M, Greene M, Francis D, Hanna M, Pena J, Escalante CR, Kurosawa A, Erdjument-Bromage H, Tempst P, Adachi N, Vezzoni P, Villa A, Aggarwal AK, Cortes P.

J Exp Med. 2012 May 7;209(5):955-63. doi: 10.1084/jem.20111437. Epub 2012 Apr 23.

15.

Effect of alcohol and kolanut interaction on brain sodium pump activity in Wistar albino rats.

Obochi GO, Abara AE, Malu SP, Obi-Abang M, Edu FE, Eteng MU, Umoh IB.

Niger J Physiol Sci. 2007 Jun-Dec;22(1-2):99-104.

PMID:
18379627
16.

Effect of caffeine-coconut products interactions on induction of microsomal drug-metabolizing enzymes in Wistar albino rats.

Abara AE, Obochi GO, Malu SP, Obi-Abang M, Ekam VS, Uboh FE.

Niger J Physiol Sci. 2007 Jun-Dec;22(1-2):75-81.

PMID:
18379623
17.

Effect of alcohol and kolanut interaction on biochemical indices of neuronal gene expression in Wistar albino rats.

Obochi GO, Abara AE, Malu SP, Ekam VS, Uboh FU, Umoh IB.

Niger J Physiol Sci. 2007 Jun-Dec;22(1-2):69-73.

PMID:
18379622
18.
19.

IFN-gamma bioassay: development of a sensitive method by measuring nitric oxide production by peritoneal exudate cells from C57BL/6 mice.

Malu S, Srinivasan S, Kumar Maiti P, Rajagopal D, John B, Nandi D.

J Immunol Methods. 2003 Jan 15;272(1-2):55-65.

PMID:
12505712
20.

Levels of plasma soluble complement receptor 1 (sCR1) in normal Indian adult population.

Sivasankar B, Raju KR, Anand V, Malu S, Padmanabhan S, Tiwari SC, Das N, Srivastava LM.

Indian J Clin Biochem. 1999 Jul;14(2):237-40. doi: 10.1007/BF02867924.

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