Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 77

1.

Receptor-Mediated Attachment and Uptake of Hyaluronan Conjugates by Breast Cancer Cells.

Shah KN, Ditto AJ, Crowder DC, Overmeyer JH, Tavana H, Maltese WA, Yun YH.

Mol Pharm. 2017 Nov 6;14(11):3968-3977. doi: 10.1021/acs.molpharmaceut.7b00636. Epub 2017 Oct 19.

PMID:
28981299
2.

Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells.

Li Z, Mbah NE, Maltese WA.

Mol Cell Biochem. 2018 Feb;439(1-2):1-9. doi: 10.1007/s11010-017-3130-x. Epub 2017 Aug 2.

PMID:
28770472
3.

Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.

Mbah NE, Overmeyer JH, Maltese WA.

Cell Biol Toxicol. 2017 Jun;33(3):263-282. doi: 10.1007/s10565-016-9369-2. Epub 2016 Nov 7.

4.

Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer indolyl-pyridinyl-propenones: Effects on potency and mode of activity.

Trabbic CJ, George SM, Alexander EM, Du S, Offenbacher JM, Crissman EJ, Overmeyer JH, Maltese WA, Erhardt PW.

Eur J Med Chem. 2016 Oct 21;122:79-91. doi: 10.1016/j.ejmech.2016.06.016. Epub 2016 Jun 13.

5.

Non-apoptotic cell death associated with perturbations of macropinocytosis.

Maltese WA, Overmeyer JH.

Front Physiol. 2015 Feb 16;6:38. doi: 10.3389/fphys.2015.00038. eCollection 2015. Review.

6.

Synthesis and biological evaluation of indolyl-pyridinyl-propenones having either methuosis or microtubule disruption activity.

Trabbic CJ, Overmeyer JH, Alexander EM, Crissman EJ, Kvale HM, Smith MA, Erhardt PW, Maltese WA.

J Med Chem. 2015 Mar 12;58(5):2489-512. doi: 10.1021/jm501997q. Epub 2015 Feb 19.

7.

Methuosis: nonapoptotic cell death associated with vacuolization of macropinosome and endosome compartments.

Maltese WA, Overmeyer JH.

Am J Pathol. 2014 Jun;184(6):1630-42. doi: 10.1016/j.ajpath.2014.02.028. Epub 2014 Apr 13. Review.

8.

Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones.

Trabbic CJ, Dietsch HM, Alexander EM, Nagy PI, Robinson MW, Overmeyer JH, Maltese WA, Erhardt PW.

ACS Med Chem Lett. 2014 Jan 9;5(1):73-77.

9.

Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death.

Robinson MW, Overmeyer JH, Young AM, Erhardt PW, Maltese WA.

J Med Chem. 2012 Mar 8;55(5):1940-56. doi: 10.1021/jm201006x. Epub 2012 Feb 28.

10.

A switch between cytoprotective and cytotoxic autophagy in the radiosensitization of breast tumor cells by chloroquine and vitamin D.

Wilson EN, Bristol ML, Di X, Maltese WA, Koterba K, Beckman MJ, Gewirtz DA.

Horm Cancer. 2011 Oct;2(5):272-85. doi: 10.1007/s12672-011-0081-7.

11.

A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells.

Overmeyer JH, Young AM, Bhanot H, Maltese WA.

Mol Cancer. 2011 Jun 6;10:69. doi: 10.1186/1476-4598-10-69.

12.

Death pathways triggered by activated Ras in cancer cells.

Overmeyer JH, Maltese WA.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1693-713. Review.

13.

Induction of nonapoptotic cell death by activated Ras requires inverse regulation of Rac1 and Arf6.

Bhanot H, Young AM, Overmeyer JH, Maltese WA.

Mol Cancer Res. 2010 Oct;8(10):1358-74. doi: 10.1158/1541-7786.MCR-10-0090. Epub 2010 Aug 16.

15.

MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development.

Alam G, Cui H, Shi H, Yang L, Ding J, Mao L, Maltese WA, Ding HF.

Am J Pathol. 2009 Aug;175(2):856-66. doi: 10.2353/ajpath.2009.090019. Epub 2009 Jul 16.

16.

Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis.

Overmeyer JH, Kaul A, Johnson EE, Maltese WA.

Mol Cancer Res. 2008 Jun;6(6):965-77. doi: 10.1158/1541-7786.MCR-07-2036.

17.

Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways.

Kaul A, Overmeyer JH, Maltese WA.

Cell Signal. 2007 May;19(5):1034-43. Epub 2006 Nov 28.

18.

Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes.

Johnson EE, Overmeyer JH, Gunning WT, Maltese WA.

J Cell Sci. 2006 Apr 1;119(Pt 7):1219-32. Epub 2006 Mar 7.

19.

Tyrosine phosphorylation of Rab proteins.

Overmeyer JH, Maltese WA.

Methods Enzymol. 2005;403:194-202.

PMID:
16473587
20.
21.

Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells.

Ding J, Soule G, Overmeyer JH, Maltese WA.

Biochem Biophys Res Commun. 2003 Dec 19;312(3):670-5.

PMID:
14680817
22.

Mutant Rab24 GTPase is targeted to nuclear inclusions.

Maltese WA, Soule G, Gunning W, Calomeni E, Alexander B.

BMC Cell Biol. 2002 Sep 25;3:25.

23.
24.

Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide.

Maltese WA, Wilson S, Tan Y, Suomensaari S, Sinha S, Barbour R, McConlogue L.

J Biol Chem. 2001 Jun 8;276(23):20267-79. Epub 2001 Mar 7.

25.

Different Rab GTPases associate preferentially with alpha or beta GDP-dissociation inhibitors.

Erdman RA, Maltese WA.

Biochem Biophys Res Commun. 2001 Mar 23;282(1):4-9.

PMID:
11263962
26.

Prenylation of Rab proteins in vitro by geranylgeranyltransferases.

Overmeyer JH, Maltese WA.

Methods Enzymol. 2001;329:31-9. No abstract available.

PMID:
11210550
28.

Expression of Rab3A GTPase and other synaptic proteins is induced in differentiated NT2N neurons.

Sheridan KM, Maltese WA.

J Mol Neurosci. 1998 Apr;10(2):121-8.

PMID:
9699153
29.

Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases.

Wilson AL, Erdman RA, Castellano F, Maltese WA.

Biochem J. 1998 Aug 1;333 ( Pt 3):497-504.

30.

Membrane targeting via protein prenylation.

Overmeyer JH, Erdman RA, Maltese WA.

Methods Mol Biol. 1998;88:249-63. No abstract available.

PMID:
9664311
31.
32.
33.
34.

Prenylation-dependent interaction of Rab proteins with GDP dissociation inhibitors.

Maltese WA, Wilson AL, Erdman RA.

Biochem Soc Trans. 1996 Aug;24(3):703-8. Review. No abstract available.

PMID:
8878830
36.

Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein.

McConlogue L, Castellano F, deWit C, Schenk D, Maltese WA.

J Biol Chem. 1996 Jan 19;271(3):1343-8.

37.
38.

Regions outside of the CAAX motif influence the specificity of prenylation of G protein gamma subunits.

Kalman VK, Erdman RA, Maltese WA, Robishaw JD.

J Biol Chem. 1995 Jun 16;270(24):14835-41.

39.
40.

Coupled translation/prenylation of Rab proteins in vitro.

Wilson AL, Maltese WA.

Methods Enzymol. 1995;250:79-91. Review. No abstract available.

PMID:
7651188
41.

Isoprenylation of Rab1B is impaired by mutations in its effector domain.

Wilson AL, Maltese WA.

J Biol Chem. 1993 Jul 15;268(20):14561-4.

42.
44.
45.

Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA.

Kinsella BT, Erdman RA, Maltese WA.

J Biol Chem. 1991 May 25;266(15):9786-94.

46.

Post-translational modification of proteins by 15-carbon and 20-carbon isoprenoids in three mammalian cell lines.

Reese JH, Maltese WA.

Mol Cell Biochem. 1991 May 29-Jun 12;104(1-2):109-16.

PMID:
1921989
48.

Posttranslational modification of proteins by isoprenoids in mammalian cells.

Maltese WA.

FASEB J. 1990 Dec;4(15):3319-28. Review.

PMID:
2123808
49.

Isoprenylation of C-terminal cysteine in a G-protein gamma subunit.

Maltese WA, Robishaw JD.

J Biol Chem. 1990 Oct 25;265(30):18071-4.

50.

Supplemental Content

Loading ...
Support Center