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Items: 1 to 50 of 94

1.

Closure of the cytoplasmic gate formed by TM5 and TM11 during transport in the oxalate/formate exchanger from Oxalobacter formigenes.

Iyalomhe O, Herrick DZ, Cafiso DS, Maloney PC.

Biochemistry. 2014 Dec 16;53(49):7735-44. doi: 10.1021/bi5012173. Epub 2014 Dec 2.

2.

Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules.

Woodward OM, Tukaye DN, Cui J, Greenwell P, Constantoulakis LM, Parker BS, Rao A, Köttgen M, Maloney PC, Guggino WB.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5223-8. doi: 10.1073/pnas.1214530110. Epub 2013 Mar 14.

3.

Nanochannel-based single molecule recycling.

Lesoine JF, Venkataraman PA, Maloney PC, Dumont ME, Novotny L.

Nano Lett. 2012 Jun 13;12(6):3273-8. doi: 10.1021/nl301341m. Epub 2012 Jun 4.

4.

Oligomeric state of the oxalate transporter, OxlT.

Kang DC, Venkataraman PA, Dumont ME, Maloney PC.

Biochemistry. 2011 Oct 4;50(39):8445-53. doi: 10.1021/bi201175y. Epub 2011 Sep 8.

5.

Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.

Lewis HA, Wang C, Zhao X, Hamuro Y, Conners K, Kearins MC, Lu F, Sauder JM, Molnar KS, Coales SJ, Maloney PC, Guggino WB, Wetmore DR, Weber PC, Hunt JF.

J Mol Biol. 2010 Feb 19;396(2):406-30. doi: 10.1016/j.jmb.2009.11.051. Epub 2009 Nov 26.

PMID:
19944699
6.
7.

Ins and outs of major facilitator superfamily antiporters.

Law CJ, Maloney PC, Wang DN.

Annu Rev Microbiol. 2008;62:289-305. doi: 10.1146/annurev.micro.61.080706.093329. Review.

8.

Cysteine scanning mutagenesis of TM5 reveals conformational changes in OxlT, the oxalate transporter of Oxalobacter formigenes.

Wang X, Ye L, McKinney CC, Feng M, Maloney PC.

Biochemistry. 2008 May 27;47(21):5709-17. doi: 10.1021/bi8001314. Epub 2008 May 2.

9.

ABC transporters: how small machines do a big job.

Davidson AL, Maloney PC.

Trends Microbiol. 2007 Oct;15(10):448-55. Epub 2007 Oct 24. Review.

PMID:
17920277
10.

Kinetic evidence is consistent with the rocker-switch mechanism of membrane transport by GlpT.

Law CJ, Yang Q, Soudant C, Maloney PC, Wang DN.

Biochemistry. 2007 Oct 30;46(43):12190-7. Epub 2007 Oct 4.

11.

Topology of AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, determined by site-directed fluorescence labeling.

Nanatani K, Fujiki T, Kanou K, Takeda-Shitaka M, Umeyama H, Ye L, Wang X, Nakajima T, Uchida T, Maloney PC, Abe K.

J Bacteriol. 2007 Oct;189(19):7089-97. Epub 2007 Jul 27.

12.
13.

Experimental tests of a homology model for OxlT, the oxalate transporter of Oxalobacter formigenes.

Yang Q, Wang X, Ye L, Mentrikoski M, Mohammadi E, Kim YM, Maloney PC.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8513-8. Epub 2005 Jun 2.

14.

Altered oxyanion selectivity in mutants of UhpT, the Pi-linked sugar phosphate carrier of Escherichia coli.

Hall JA, Maloney PC.

J Biol Chem. 2005 Feb 4;280(5):3376-81. Epub 2004 Nov 19.

15.

Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure.

Lewis HA, Zhao X, Wang C, Sauder JM, Rooney I, Noland BW, Lorimer D, Kearins MC, Conners K, Condon B, Maloney PC, Guggino WB, Hunt JF, Emtage S.

J Biol Chem. 2005 Jan 14;280(2):1346-53. Epub 2004 Nov 3.

16.
17.

Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.

Lewis HA, Buchanan SG, Burley SK, Conners K, Dickey M, Dorwart M, Fowler R, Gao X, Guggino WB, Hendrickson WA, Hunt JF, Kearins MC, Lorimer D, Maloney PC, Post KW, Rajashankar KR, Rutter ME, Sauder JM, Shriver S, Thibodeau PH, Thomas PJ, Zhang M, Zhao X, Emtage S.

EMBO J. 2004 Jan 28;23(2):282-93. Epub 2003 Dec 18.

18.
19.

Structural model for 12-helix transporters belonging to the major facilitator superfamily.

Hirai T, Heymann JA, Maloney PC, Subramaniam S.

J Bacteriol. 2003 Mar;185(5):1712-8.

20.

Three-dimensional structure of a bacterial oxalate transporter.

Hirai T, Heymann JA, Shi D, Sarker R, Maloney PC, Subramaniam S.

Nat Struct Biol. 2002 Aug;9(8):597-600.

PMID:
12118242
22.

Plasmid-encoded asp operon confers a proton motive metabolic cycle catalyzed by an aspartate-alanine exchange reaction.

Abe K, Ohnishi F, Yagi K, Nakajima T, Higuchi T, Sano M, Machida M, Sarker RI, Maloney PC.

J Bacteriol. 2002 Jun;184(11):2906-13.

24.

Intracellular cysteines of the cystic fibrosis transmembrane conductance regulator (CFTR) modulate channel gating.

Ketchum CJ, Yue H, Alessi KA, Devidas S, Guggino WB, Maloney PC.

Cell Physiol Biochem. 2002;12(1):1-8.

PMID:
11914543
25.

Projection structure and molecular architecture of OxlT, a bacterial membrane transporter.

Heymann JA, Sarker R, Hirai T, Shi D, Milne JL, Maloney PC, Subramaniam S.

EMBO J. 2001 Aug 15;20(16):4408-13.

26.

Helix proximity in OxlT, the oalate:formate antiporter of oxalobacter formigenes. Cross-linking between TM2 and TM11.

Kim YM, Ye L, Maloney PC.

J Biol Chem. 2001 Sep 28;276(39):36681-6. Epub 2001 Jul 16.

27.

The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export.

Ketchum CJ, Schmidt WK, Rajendrakumar GV, Michaelis S, Maloney PC.

J Biol Chem. 2001 Aug 3;276(31):29007-11. Epub 2001 Jun 1.

29.
30.
31.
32.

Structure of the water channel AqpZ from Escherichia coli revealed by electron crystallography.

Ringler P, Borgnia MJ, Stahlberg H, Maloney PC, Agre P, Engel A.

J Mol Biol. 1999 Sep 3;291(5):1181-90.

PMID:
10518953
33.

Functional reconstitution and characterization of AqpZ, the E. coli water channel protein.

Borgnia MJ, Kozono D, Calamita G, Maloney PC, Agre P.

J Mol Biol. 1999 Sep 3;291(5):1169-79.

PMID:
10518952
34.
35.

Functional symmetry of UhpT, the sugar phosphate transporter of Escherichia coli.

Fann MC, Maloney PC.

J Biol Chem. 1998 Dec 11;273(50):33735-40.

36.

Identification of cystic fibrosis transmembrane conductance regulator in renal endosomes.

Crawford IT, Maloney PC.

Methods Enzymol. 1998;292:652-63. No abstract available.

PMID:
9711589
37.

Identification of two essential arginine residues in UhpT, the sugar phosphate antiporter of Escherichia coli.

Fann M, Davies AH, Varadhachary A, Kuroda T, Sevier C, Tsuchiya T, Maloney PC.

J Membr Biol. 1998 Jul 15;164(2):187-95.

PMID:
9662562
39.

Purification of UhpT, the sugar phosphate transporter of Escherichia coli.

Tamai E, Fann MC, Tsuchiya T, Maloney PC.

Protein Expr Purif. 1997 Jul;10(2):275-82.

PMID:
9226724
41.
42.
43.

Exchange of aspartate and alanine. Mechanism for development of a proton-motive force in bacteria.

Abe K, Hayashi H, Maloney PC.

J Biol Chem. 1996 Feb 9;271(6):3079-84. Erratum in: J Biol Chem 1996 Nov 8;271(45):28725. Malone PC [corrected to Maloney PC].

44.

Residues in the pathway through a membrane transporter.

Yan RT, Maloney PC.

Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5973-6.

45.

Bacterial anion exchange: reductionist and integrative approaches to membrane biology.

Maloney PC, Yan RT, Abe K.

J Exp Biol. 1994 Nov;196:471-82. Review.

46.

Bacterial and plant antiporters.

Maloney PC.

J Exp Biol. 1994 Nov;196:439-42. Review. No abstract available.

47.

Bacterial transporters.

Maloney PC.

Curr Opin Cell Biol. 1994 Aug;6(4):571-82. Review.

PMID:
7986535
48.
49.

The evolution of membrane carriers.

Maloney PC, Wilson TH.

Soc Gen Physiol Ser. 1993;48:147-60. No abstract available.

PMID:
8503041
50.

The molecular and cell biology of anion transport by bacteria.

Maloney PC.

Bioessays. 1992 Nov;14(11):757-62. Review.

PMID:
1365888

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