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Items: 40

1.

Peptide-Cleavable Self-immolative Maytansinoid Antibody-Drug Conjugates Designed To Provide Improved Bystander Killing.

Costoplus JA, Veale KH, Qiu Q, Ponte JF, Lanieri L, Setiady Y, Dong L, Skaletskaya A, Bartle LM, Salomon P, Wu R, Maloney EK, Kovtun YV, Ab O, Lai K, Chari RVJ, Widdison WC.

ACS Med Chem Lett. 2019 Sep 27;10(10):1393-1399. doi: 10.1021/acsmedchemlett.9b00310. eCollection 2019 Oct 10.

PMID:
31620224
2.

Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates.

Li W, Veale KH, Qiu Q, Sinkevicius KW, Maloney EK, Costoplus JA, Lau J, Evans HL, Setiady Y, Ab O, Abbott SM, Lee J, Wisitpitthaya S, Skaletskaya A, Wang L, Keating TA, Chari RVJ, Widdison WC.

ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392. doi: 10.1021/acsmedchemlett.9b00301. eCollection 2019 Oct 10.

PMID:
31620223
3.

Optimizing lysosomal activation of antibody-drug conjugates (ADCs) by incorporation of novel cleavable dipeptide linkers.

Salomon PL, Reid EE, Archer KE, Harris L, Maloney EK, Wilhelm AJ, Miller ML, Chari RVJ, Keating TA, Singh R.

Mol Pharm. 2019 Oct 14. doi: 10.1021/acs.molpharmaceut.9b00696. [Epub ahead of print]

PMID:
31609629
4.

Attitudinal Spillover from Misleading Natural Cigarette Marketing: An Experiment Examining Current and Former Smokers' Support for Tobacco Industry Regulation.

Gratale SK, Sangalang A, Maloney EK, Cappella JN.

Int J Environ Res Public Health. 2019 Sep 23;16(19). pii: E3554. doi: 10.3390/ijerph16193554.

5.

Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody-Drug Conjugates (ADCs).

Archer KE, Reid EE, Shizuka M, Woods J, Harris L, Maloney EK, Bartle LM, Ab O, Wilhelm A, Setiady Y, Ponte JF, Singh R, Keating TA, Chari RVJ, Miller ML.

ACS Med Chem Lett. 2019 Jul 22;10(8):1211-1215. doi: 10.1021/acsmedchemlett.9b00254. eCollection 2019 Aug 8.

PMID:
31413807
6.

Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs).

Reid EE, Archer KE, Shizuka M, Wilhelm A, Yoder NC, Bai C, Fishkin NE, Harris L, Maloney EK, Salomon P, Hong E, Wu R, Ab O, Jin S, Lai KC, Sikka S, Chari RVJ, Miller ML.

ACS Med Chem Lett. 2019 Jul 10;10(8):1193-1197. doi: 10.1021/acsmedchemlett.9b00240. eCollection 2019 Aug 8.

PMID:
31413805
7.

The Effects of Graphic Warning Labels' Vividness on Message Engagement and Intentions to Quit Smoking.

Yotam O, Emily B, Maloney EK, Cappella JN.

Communic Res. 2019 Jul;46(5):619-638. doi: 10.1177/0093650217700226. Epub 2017 Apr 2.

PMID:
31371841
8.

Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs).

Reid EE, Archer KE, Shizuka M, McShea MA, Maloney EK, Ab O, Lanieri L, Wilhelm A, Ponte JF, Yoder NC, Chari RVJ, Miller ML.

Bioorg Med Chem Lett. 2019 Sep 1;29(17):2455-2458. doi: 10.1016/j.bmcl.2019.07.031. Epub 2019 Jul 19.

PMID:
31350125
9.

A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation.

Yoder NC, Bai C, Tavares D, Widdison WC, Whiteman KR, Wilhelm A, Wilhelm SD, McShea MA, Maloney EK, Ab O, Wang L, Jin S, Erickson HK, Keating TA, Lambert JM.

Mol Pharm. 2019 Sep 3;16(9):3926-3937. doi: 10.1021/acs.molpharmaceut.9b00529. Epub 2019 Jul 31.

PMID:
31287952
10.

Regulating language, not inference: an examination of the potential effectiveness of Natural American Spirit advertising restrictions.

Gratale SK, Maloney EK, Cappella JN.

Tob Control. 2019 Aug;28(e1):e43-e48. doi: 10.1136/tobaccocontrol-2018-054707. Epub 2019 Jan 29.

PMID:
30696786
11.

When Visual Cues Activate Moral Foundations: Unintended Effects of Visual Portrayals of Vaping within Electronic Cigarette Video Advertisements.

Yang S, Maloney EK, Tan ASL, Cappella JN.

Hum Commun Res. 2018 Jul;44(3):223-246. doi: 10.1093/hcr/hqy004. Epub 2018 Mar 30.

12.

Does Interest in Smoking Affect Youth Selection of Pro-smoking Videos? A Selective Exposure Experiment.

Bae RE, Maloney EK, AlbarracĂ­n D, Cappella JN.

Nicotine Tob Res. 2019 Mar 30;21(4):539-546. doi: 10.1093/ntr/nty037.

13.

A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody-Drug Conjugates (ADCs).

Miller ML, Shizuka M, Wilhelm A, Salomon P, Reid EE, Lanieri L, Sikka S, Maloney EK, Harvey L, Qiu Q, Archer KE, Bai C, Vitharana D, Harris L, Singh R, Ponte JF, Yoder NC, Kovtun Y, Lai KC, Ab O, Pinkas J, Keating TA, Chari RVJ.

Mol Cancer Ther. 2018 Mar;17(3):650-660. doi: 10.1158/1535-7163.MCT-17-0940. Epub 2018 Feb 13.

14.

A Randomized Trial of the Effect of Youth Appealing E-Cigarette Advertising on Susceptibility to Use E-Cigarettes Among Youth.

Padon AA, Lochbuehler K, Maloney EK, Cappella JN.

Nicotine Tob Res. 2018 Jul 9;20(8):954-961. doi: 10.1093/ntr/ntx155.

15.

Influence of Natural American Spirit advertising on current and former smokers' perceptions and intentions.

Gratale SK, Maloney EK, Sangalang A, Cappella JN.

Tob Control. 2018 Sep;27(5):498-504. doi: 10.1136/tobaccocontrol-2017-053881. Epub 2017 Oct 21.

PMID:
29055882
16.

Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates.

Sun X, Ponte JF, Yoder NC, Laleau R, Coccia J, Lanieri L, Qiu Q, Wu R, Hong E, Bogalhas M, Wang L, Dong L, Setiady Y, Maloney EK, Ab O, Zhang X, Pinkas J, Keating TA, Chari R, Erickson HK, Lambert JM.

Bioconjug Chem. 2017 May 17;28(5):1371-1381. doi: 10.1021/acs.bioconjchem.7b00062. Epub 2017 Apr 13.

PMID:
28388844
17.

Treatment decision making in early-stage papillary thyroid cancer.

D'Agostino TA, Shuk E, Maloney EK, Zeuren R, Tuttle RM, Bylund CL.

Psychooncology. 2018 Jan;27(1):61-68. doi: 10.1002/pon.4383. Epub 2017 Feb 27.

18.

Youth-Targeted E-cigarette Marketing in the US.

Padon AA, Maloney EK, Cappella JN.

Tob Regul Sci. 2017 Jan;3(1):95-101. doi: 10.18001/TRS.3.1.9.

19.

Potential Effectiveness of Pictorial Warning Labels That Feature the Images and Personal Details of Real People.

Brennan E, Maloney EK, Ophir Y, Cappella JN.

Nicotine Tob Res. 2017 Oct 1;19(10):1138-1148. doi: 10.1093/ntr/ntw319.

20.

A New Class of Antibody-Drug Conjugates with Potent DNA Alkylating Activity.

Miller ML, Fishkin NE, Li W, Whiteman KR, Kovtun Y, Reid EE, Archer KE, Maloney EK, Audette CA, Mayo MF, Wilhelm A, Modafferi HA, Singh R, Pinkas J, Goldmacher V, Lambert JM, Chari RV.

Mol Cancer Ther. 2016 Aug;15(8):1870-8. doi: 10.1158/1535-7163.MCT-16-0184. Epub 2016 May 23.

21.

Discussing Death, Dying, and End-of-Life Goals of Care: A Communication Skills Training Module for Oncology Nurses.

Coyle N, Manna R, Shen M, Banerjee SC, Penn S, Pehrson C, Krueger CA, Maloney EK, Zaider T, Bylund CL.

Clin J Oncol Nurs. 2015 Dec;19(6):697-702. doi: 10.1188/15.CJON.697-702.

22.

Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing.

Widdison WC, Ponte JF, Coccia JA, Lanieri L, Setiady Y, Dong L, Skaletskaya A, Hong EE, Wu R, Qiu Q, Singh R, Salomon P, Fishkin N, Harris L, Maloney EK, Kovtun Y, Veale K, Wilhelm SD, Audette CA, Costoplus JA, Chari RV.

Bioconjug Chem. 2015 Nov 18;26(11):2261-78. doi: 10.1021/acs.bioconjchem.5b00430. Epub 2015 Sep 30.

PMID:
26355774
23.

Does Vaping in E-Cigarette Advertisements Affect Tobacco Smoking Urge, Intentions, and Perceptions in Daily, Intermittent, and Former Smokers?

Maloney EK, Cappella JN.

Health Commun. 2016;31(1):129-38. doi: 10.1080/10410236.2014.993496. Epub 2015 Mar 11.

PMID:
25758192
24.

Sources and types of online information that breast cancer patients read and discuss with their doctors.

Maloney EK, D'Agostino TA, Heerdt A, Dickler M, Li Y, Ostroff JS, Bylund CL.

Palliat Support Care. 2015 Apr;13(2):107-14. doi: 10.1017/S1478951513000862. Epub 2013 Nov 4.

25.

Communication skills training for oncology professionals.

Kissane DW, Bylund CL, Banerjee SC, Bialer PA, Levin TT, Maloney EK, D'Agostino TA.

J Clin Oncol. 2012 Apr 10;30(11):1242-7. doi: 10.1200/JCO.2011.39.6184. Epub 2012 Mar 12. Review.

26.

A novel pathway for maytansinoid release from thioether linked antibody-drug conjugates (ADCs) under oxidative conditions.

Fishkin N, Maloney EK, Chari RV, Singh R.

Chem Commun (Camb). 2011 Oct 14;47(38):10752-4. doi: 10.1039/c1cc14164c. Epub 2011 Aug 26.

PMID:
21874179
27.

The down low, social stigma, and risky sexual behaviors: insights from African-American men who have sex with men.

Lapinski MK, Braz ME, Maloney EK.

J Homosex. 2010;57(5):610-33. doi: 10.1080/00918361003712020.

PMID:
20455133
28.

Antibody-maytansinoid conjugates designed to bypass multidrug resistance.

Kovtun YV, Audette CA, Mayo MF, Jones GE, Doherty H, Maloney EK, Erickson HK, Sun X, Wilhelm S, Ab O, Lai KC, Widdison WC, Kellogg B, Johnson H, Pinkas J, Lutz RJ, Singh R, Goldmacher VS, Chari RV.

Cancer Res. 2010 Mar 15;70(6):2528-37. doi: 10.1158/0008-5472.CAN-09-3546. Epub 2010 Mar 2.

29.

Knowledge and Use of Low Vision Services Among Persons with Age-related Macular Degeneration.

Casten RJ, Maloney EK, Rovner BW.

J Vis Impair Blind. 2005;99(11):720-724. No abstract available.

30.

An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation.

Maloney EK, McLaughlin JL, Dagdigian NE, Garrett LM, Connors KM, Zhou XM, Blättler WA, Chittenden T, Singh R.

Cancer Res. 2003 Aug 15;63(16):5073-83.

31.
32.

trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals.

Maloney EK, Waxman DJ.

Toxicol Appl Pharmacol. 1999 Dec 1;161(2):209-18.

PMID:
10581215
33.

Reduction of endothelial cell related TGFbeta activity by thiols.

White AC, Maloney EK, Lee SL, Lanzillo JJ, Fanburg BL.

Endothelium. 1999;6(3):231-9.

PMID:
10365774
34.

Crayfish: a newly recognized vehicle for vibrio infections.

Bean NH, Maloney EK, Potter ME, Korazemo P, Ray B, Taylor JP, Seigler S, Snowden J.

Epidemiol Infect. 1998 Oct;121(2):269-73.

35.

Using laboratory-based surveillance data for prevention: an algorithm for detecting Salmonella outbreaks.

Hutwagner LC, Maloney EK, Bean NH, Slutsker L, Martin SM.

Emerg Infect Dis. 1997 Jul-Sep;3(3):395-400.

36.

Transforming growth factor B1 decreases uptake of glutathione precursor amino acids in bovine pulmonary artery endothelial cells.

Boustani MR, Hertig IA, Maloney EK, Fanburg BL, White AC.

Endothelium. 1997;5(1):1-10.

PMID:
9142317
37.

A competitive quantitative polymerase chain reaction assay for bovine transforming growth factor-B1 mRNA.

Lanzillo JJ, Maloney EK, White AC, Stevens J, Fanburg B.

Life Sci. 1996;59(25-26):2157-65.

PMID:
8950319
38.

Nitric oxide increases cellular glutathione levels in rat lung fibroblasts.

White AC, Maloney EK, Boustani MR, Hassoun PM, Fanburg BL.

Am J Respir Cell Mol Biol. 1995 Oct;13(4):442-8.

PMID:
7546774
39.

Increase in antimicrobial-resistant Salmonella infections in the United States, 1989-1990.

Lee LA, Puhr ND, Maloney EK, Bean NH, Tauxe RV.

J Infect Dis. 1994 Jul;170(1):128-34.

PMID:
8014487
40.

Evaluation of birth defect histories obtained through maternal interviews.

Rasmussen SA, Mulinare J, Khoury MJ, Maloney EK.

Am J Hum Genet. 1990 Mar;46(3):478-85.

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