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Items: 1 to 50 of 115

1.

Pathogenic citrulline-multispecific B cell receptor clades in rheumatoid arthritis.

Titcombe PJ, Wigerblade G, Sippl N, Zhang N, Shmagel AK, Sahlström P, Zhang Y, Barsness LO, Ghodke-Puranik Y, Baharpoor A, Hansson M, Israelsson L, Skriner K, Niewold TB, Klareskog L, Svensson CI, Amara K, Malmström V, Mueller DL.

Arthritis Rheumatol. 2018 Jun 21. doi: 10.1002/art.40590. [Epub ahead of print]

PMID:
29927106
2.

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.

Pieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V.

J Autoimmun. 2018 May 28. pii: S0896-8411(18)30128-8. doi: 10.1016/j.jaut.2018.04.004. [Epub ahead of print]

PMID:
29853344
3.

Rituximab-mediated late-onset neutropenia in systemic lupus erythematosus - distinct roles of BAFF and APRIL.

Parodis I, Söder F, Faustini F, Kasza Z, Samuelsson I, Zickert A, Svenungsson E, van Vollenhoven RF, Malmström V, Wermeling F, Gunnarsson I.

Lupus. 2018 Aug;27(9):1470-1478. doi: 10.1177/0961203318777116. Epub 2018 May 21.

PMID:
29783918
4.

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection.

Lloyd KA, Steen J, Amara K, Titcombe PJ, Israelsson L, Lundström SL, Zhou D, Zubarev RA, Reed E, Piccoli L, Gabay C, Lanzavecchia A, Baeten D, Lundberg K, Mueller DL, Klareskog L, Malmström V, Grönwall C.

Eur J Immunol. 2018 Jun;48(6):1030-1045. doi: 10.1002/eji.201747446. Epub 2018 Apr 6.

PMID:
29512823
5.

T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus.

Houtman M, Shchetynsky K, Chemin K, Hensvold AH, Ramsköld D, Tandre K, Eloranta ML, Rönnblom L, Uebe S, Catrina AI, Malmström V, Padyukov L.

J Autoimmun. 2018 Jun;90:28-38. doi: 10.1016/j.jaut.2018.01.003. Epub 2018 Feb 3.

6.

EOMES-positive CD4+ T cells are increased in PTPN22 (1858T) risk allele carriers.

Chemin K, Ramsköld D, Diaz-Gallo LM, Herrath J, Houtman M, Tandre K, Rönnblom L, Catrina A, Malmström V.

Eur J Immunol. 2018 Apr;48(4):655-669. doi: 10.1002/eji.201747296. Epub 2018 Feb 28.

PMID:
29388193
7.

Corrigendum: Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2017 Oct 4;8:1236. doi: 10.3389/fimmu.2017.01236. eCollection 2017.

8.

H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production.

Brauner S, Folkersen L, Kvarnström M, Meisgen S, Petersen S, Franzén-Malmros M, Mofors J, Brokstad KA, Klareskog L, Jonsson R, Westerberg LS, Trollmo C, Malmström V, Ambrosi A, Kuchroo VK, Nordmark G, Wahren-Herlenius M.

Ann Rheum Dis. 2017 Oct;76(10):1755-1763. doi: 10.1136/annrheumdis-2016-210509. Epub 2017 Jul 31.

9.

Immunoglobulin characteristics and RNAseq data of FcRL4+ B cells sorted from synovial fluid and tissue of patients with rheumatoid arthritis.

Amara K, Clay E, Yeo L, Ramsköld D, Spengler J, Sippl N, Cameron J, Israelsson L, Titcombe PJ, Grönwall C, Sahbudin I, Filer A, Raza K, Malmström V, Scheel-Toellner D.

Data Brief. 2017 Jun 7;13:356-370. doi: 10.1016/j.dib.2017.06.009. eCollection 2017 Aug.

10.

Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis.

Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ.

J Autoimmun. 2017 Nov;84:29-45. doi: 10.1016/j.jaut.2017.06.004. Epub 2017 Jun 21.

PMID:
28647488
11.

B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis.

Amara K, Clay E, Yeo L, Ramsköld D, Spengler J, Sippl N, Cameron JA, Israelsson L, Titcombe PJ, Grönwall C, Sahbudin I, Filer A, Raza K, Malmström V, Scheel-Toellner D.

J Autoimmun. 2017 Jul;81:34-43. doi: 10.1016/j.jaut.2017.03.004. Epub 2017 Mar 24.

12.

Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus.

Parodis I, Sjöwall C, Jönsen A, Ramsköld D, Zickert A, Frodlund M, Sohrabian A, Arnaud L, Rönnelid J, Malmström V, Bengtsson AA, Gunnarsson I.

Autoimmun Rev. 2017 Apr;16(4):343-351. doi: 10.1016/j.autrev.2017.02.005. Epub 2017 Feb 13. Review.

PMID:
28216072
13.

Mechanisms leading from systemic autoimmunity to joint-specific disease in rheumatoid arthritis.

Catrina AI, Svensson CI, Malmström V, Schett G, Klareskog L.

Nat Rev Rheumatol. 2017 Feb;13(2):79-86. doi: 10.1038/nrrheum.2016.200. Epub 2016 Dec 15. Review.

PMID:
27974851
14.

The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting.

Malmström V, Catrina AI, Klareskog L.

Nat Rev Immunol. 2017 Jan;17(1):60-75. doi: 10.1038/nri.2016.124. Epub 2016 Dec 5. Review.

PMID:
27916980
15.

Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells.

Joshua V, Schobers L, Titcombe PJ, Israelsson L, Rönnelid J, Hansson M, Catrina AI, Pruijn GJ, Malmström V.

Arthritis Res Ther. 2016 Dec 1;18(1):284.

16.

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre C, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2016 Nov 14;7:494. eCollection 2016. Erratum in: Front Immunol. 2017 Oct 04;8:1236.

17.

Reply.

Malmström V, Pandya JM, Lundberg IE, Fasth AE.

Arthritis Rheumatol. 2017 Jan;69(1):243-244. doi: 10.1002/art.39941. No abstract available.

18.

Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.

Folkersen L, Brynedal B, Diaz-Gallo LM, Ramsköld D, Shchetynsky K, Westerlind H, Sundström Y, Schepis D, Hensvold A, Vivar N, Eloranta ML, Rönnblom L, Brunak S, Malmström V, Catrina A, Moerch UG, Klareskog L, Padyukov L, Berg L.

Mol Med. 2016 Aug 15;22. doi: 10.2119/molmed.2016.00078. [Epub ahead of print]

19.

Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples.

Heyder T, Kohler M, Tarasova NK, Haag S, Rutishauser D, Rivera NV, Sandin C, Mia S, Malmström V, Wheelock ÅM, Wahlström J, Holmdahl R, Eklund A, Zubarev RA, Grunewald J, Ytterberg AJ.

Mol Cell Proteomics. 2016 Sep;15(9):3017-29. doi: 10.1074/mcp.M116.060764. Epub 2016 Jul 24.

20.

Antiphospholipid Antibodies in Lupus Nephritis.

Parodis I, Arnaud L, Gerhardsson J, Zickert A, Sundelin B, Malmström V, Svenungsson E, Gunnarsson I.

PLoS One. 2016 Jun 23;11(6):e0158076. doi: 10.1371/journal.pone.0158076. eCollection 2016.

21.

Effects of conventional immunosuppressive treatment on CD244+ (CD28null) and FOXP3+ T cells in the inflamed muscle of patients with polymyositis and dermatomyositis.

Pandya JM, Loell I, Hossain MS, Zong M, Alexanderson H, Raghavan S, Lundberg IE, Malmström V.

Arthritis Res Ther. 2016 Apr 1;18:80. doi: 10.1186/s13075-016-0974-5.

22.

Late-onset neutropenia after rituximab in ANCA-associated vasculitis.

Knight A, Sundström Y, Börjesson O, Bruchfeld A, Malmström V, Gunnarsson I.

Scand J Rheumatol. 2016 Oct;45(5):404-7. doi: 10.3109/03009742.2016.1138318. Epub 2016 Mar 7.

PMID:
26948245
23.

Reply.

Chemin K, Albrecht I, Pollastro S, de Vries N, Holmdahl R, Malmström V.

Arthritis Rheumatol. 2016 Aug;68(8):2053-4. doi: 10.1002/art.39660. No abstract available.

24.

CD4+ and CD8+ CD28(null) T Cells Are Cytotoxic to Autologous Muscle Cells in Patients With Polymyositis.

Pandya JM, Venalis P, Al-Khalili L, Shahadat Hossain M, Stache V, Lundberg IE, Malmström V, Fasth AE.

Arthritis Rheumatol. 2016 Aug;68(8):2016-26. doi: 10.1002/art.39650.

25.

Is rheumatoid arthritis an autoimmune disease?

Chemin K, Klareskog L, Malmström V.

Curr Opin Rheumatol. 2016 Mar;28(2):181-8. doi: 10.1097/BOR.0000000000000253. Review.

PMID:
26780425
26.

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis.

Chemin K, Pollastro S, James E, Ge C, Albrecht I, Herrath J, Gerstner C, Tandre K, Sampaio Rizzi T, Rönnblom L, Catrina A, Holmdahl R, Klareskog L, de Vries N, Malmström V.

Arthritis Rheumatol. 2016 May;68(5):1124-35. doi: 10.1002/art.39553.

27.

Mechanisms involved in triggering rheumatoid arthritis.

Catrina AI, Joshua V, Klareskog L, Malmström V.

Immunol Rev. 2016 Jan;269(1):162-74. doi: 10.1111/imr.12379. Review.

PMID:
26683152
28.

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.

Wigerblad G, Bas DB, Fernades-Cerqueira C, Krishnamurthy A, Nandakumar KS, Rogoz K, Kato J, Sandor K, Su J, Jimenez-Andrade JM, Finn A, Bersellini Farinotti A, Amara K, Lundberg K, Holmdahl R, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Svensson CI.

Ann Rheum Dis. 2016 Apr;75(4):730-8. doi: 10.1136/annrheumdis-2015-208094. Epub 2015 Nov 27.

29.

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss.

Krishnamurthy A, Joshua V, Haj Hensvold A, Jin T, Sun M, Vivar N, Ytterberg AJ, Engström M, Fernandes-Cerqueira C, Amara K, Magnusson M, Wigerblad G, Kato J, Jiménez-Andrade JM, Tyson K, Rapecki S, Lundberg K, Catrina SB, Jakobsson PJ, Svensson C, Malmström V, Klareskog L, Wähämaa H, Catrina AI.

Ann Rheum Dis. 2016 Apr;75(4):721-9. doi: 10.1136/annrheumdis-2015-208093. Epub 2015 Nov 26.

30.

IL-1R1 is expressed on both Helios(+) and Helios(-) FoxP3(+) CD4(+) T cells in the rheumatic joint.

Müller M, Herrath J, Malmström V.

Clin Exp Immunol. 2015 Oct;182(1):90-100. doi: 10.1111/cei.12668. Epub 2015 Jul 30.

31.

IL-17 and IL-23 in lupus nephritis - association to histopathology and response to treatment.

Zickert A, Amoudruz P, Sundström Y, Rönnelid J, Malmström V, Gunnarsson I.

BMC Immunol. 2015 Feb 12;16:7. doi: 10.1186/s12865-015-0070-7.

32.

Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss.

Harre U, Lang SC, Pfeifle R, Rombouts Y, Frühbeißer S, Amara K, Bang H, Lux A, Koeleman CA, Baum W, Dietel K, Gröhn F, Malmström V, Klareskog L, Krönke G, Kocijan R, Nimmerjahn F, Toes RE, Herrmann M, Scherer HU, Schett G.

Nat Commun. 2015 Mar 31;6:6651. doi: 10.1038/ncomms7651.

33.

Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephritis based on clinical and histopathological outcome following induction therapy.

Parodis I, Zickert A, Sundelin B, Axelsson M, Gerhardsson J, Svenungsson E, Malmström V, Gunnarsson I.

Lupus Sci Med. 2015 Jan 22;2(1):e000061. doi: 10.1136/lupus-2014-000061. eCollection 2015. Erratum in: Lupus Sci Med. 2015;2(1). pii: lupus-2014-000061corr1. doi: 10.1136/lupus-2014-000061corr1.

34.

IgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, Fc-glycans and a fab-Peptide sequence.

Lundström SL, Fernandes-Cerqueira C, Ytterberg AJ, Ossipova E, Hensvold AH, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Lundberg K, Zubarev RA.

PLoS One. 2014 Nov 26;9(11):e113924. doi: 10.1371/journal.pone.0113924. eCollection 2014.

35.

Expression of BAFF receptors in muscle tissue of myositis patients with anti-Jo-1 or anti-Ro52/anti-Ro60 autoantibodies.

Kryštůfková O, Barbasso Helmers S, Venalis P, Malmström V, Lindroos E, Vencovský J, Lundberg IE.

Arthritis Res Ther. 2014 Oct 10;16(5):454. doi: 10.1186/s13075-014-0454-8.

36.

Accelerating translational research by clinically driven development of an informatics platform--a case study.

Abugessaisa I, Saevarsdottir S, Tsipras G, Lindblad S, Sandin C, Nikamo P, Ståhle M, Malmström V, Klareskog L, Tegnér J.

PLoS One. 2014 Sep 9;9(9):e104382. doi: 10.1371/journal.pone.0104382. eCollection 2014.

37.

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis.

Snir O, Gomez-Cabrero D, Montes A, Perez-Pampin E, Gómez-Reino JJ, Seddighzadeh M, Klich KU, Israelsson L, Ding B, Catrina AI, Holmdahl R, Alfredsson L, Klareskog L, Tegnér J, Gonzalez A, Malmström V, Padyukov L.

Arthritis Res Ther. 2014 Aug 20;16(4):414. doi: 10.1186/s13075-014-0414-3.

38.

Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.

Ossipova E, Cerqueira CF, Reed E, Kharlamova N, Israelsson L, Holmdahl R, Nandakumar KS, Engström M, Harre U, Schett G, Catrina AI, Malmström V, Sommarin Y, Klareskog L, Jakobsson PJ, Lundberg K.

Arthritis Res Ther. 2014 Aug 12;16(4):R167. doi: 10.1186/ar4683.

39.

Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis.

Catrina AI, Ytterberg AJ, Reynisdottir G, Malmström V, Klareskog L.

Nat Rev Rheumatol. 2014 Nov;10(11):645-53. doi: 10.1038/nrrheum.2014.115. Epub 2014 Jul 29. Review.

PMID:
25072264
40.

Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice.

Lindh I, Snir O, Lönnblom E, Uysal H, Andersson I, Nandakumar KS, Vierboom M, 't Hart B, Malmström V, Holmdahl R.

Arthritis Res Ther. 2014 Jul 8;16(4):R143. doi: 10.1186/ar4605.

41.

Surface expression of CD39 identifies an enriched Treg-cell subset in the rheumatic joint, which does not suppress IL-17A secretion.

Herrath J, Chemin K, Albrecht I, Catrina AI, Malmström V.

Eur J Immunol. 2014 Oct;44(10):2979-89. doi: 10.1002/eji.201344140. Epub 2014 Aug 25.

42.

Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.

Ytterberg AJ, Joshua V, Reynisdottir G, Tarasova NK, Rutishauser D, Ossipova E, Haj Hensvold A, Eklund A, Sköld CM, Grunewald J, Malmström V, Jakobsson PJ, Rönnelid J, Padyukov L, Zubarev RA, Klareskog L, Catrina AI.

Ann Rheum Dis. 2015 Sep;74(9):1772-7. doi: 10.1136/annrheumdis-2013-204912. Epub 2014 May 9.

PMID:
24817415
43.

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

Jiang X, Trouw LA, van Wesemael TJ, Shi J, Bengtsson C, Källberg H, Malmström V, Israelsson L, Hreggvidsdottir H, Verduijn W, Klareskog L, Alfredsson L, Huizinga TW, Toes RE, Lundberg K, van der Woude D.

Ann Rheum Dis. 2014 Oct;73(10):1761-8. doi: 10.1136/annrheumdis-2013-205109. Epub 2014 May 8.

PMID:
24812286
44.

Autoimmune priming, tissue attack and chronic inflammation - the three stages of rheumatoid arthritis.

Holmdahl R, Malmström V, Burkhardt H.

Eur J Immunol. 2014 Jun;44(6):1593-9. doi: 10.1002/eji.201444486. Epub 2014 May 3. Review.

45.

Naturally occurring human phosphorylcholine antibodies are predominantly products of affinity-matured B cells in the adult.

Fiskesund R, Steen J, Amara K, Murray F, Szwajda A, Liu A, Douagi I, Malmström V, Frostegård J.

J Immunol. 2014 May 15;192(10):4551-9. doi: 10.4049/jimmunol.1303035. Epub 2014 Apr 11.

46.

Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

Nielsen N, Pascal V, Fasth AE, Sundström Y, Galsgaard ED, Ahern D, Andersen M, Baslund B, Bartels EM, Bliddal H, Feldmann M, Malmström V, Berg L, Spee P, Söderström K.

Immunology. 2014 Aug;142(4):581-93. doi: 10.1111/imm.12271.

47.

Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy.

James EA, Rieck M, Pieper J, Gebe JA, Yue BB, Tatum M, Peda M, Sandin C, Klareskog L, Malmström V, Buckner JH.

Arthritis Rheumatol. 2014 Jul;66(7):1712-22. doi: 10.1002/art.38637.

48.

An optimized protocol for human M2 macrophages using M-CSF and IL-4/IL-10/TGF-β yields a dominant immunosuppressive phenotype.

Mia S, Warnecke A, Zhang XM, Malmström V, Harris RA.

Scand J Immunol. 2014 May;79(5):305-14. doi: 10.1111/sji.12162.

49.

Peripheral and site-specific CD4(+) CD28(null) T cells from rheumatoid arthritis patients show distinct characteristics.

Pieper J, Johansson S, Snir O, Linton L, Rieck M, Buckner JH, Winqvist O, van Vollenhoven R, Malmström V.

Scand J Immunol. 2014 Feb;79(2):149-55. doi: 10.1111/sji.12139.

50.

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.

Hensvold AH, Magnusson PK, Joshua V, Hansson M, Israelsson L, Ferreira R, Jakobsson PJ, Holmdahl R, Hammarström L, Malmström V, Askling J, Klareskog L, Catrina AI.

Ann Rheum Dis. 2015 Feb;74(2):375-80. doi: 10.1136/annrheumdis-2013-203947. Epub 2013 Nov 25.

PMID:
24276366

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