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Items: 1 to 50 of 106

1.

Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma.

Munck Af Rosenschöld M, Johannesson P, Nikitidis A, Tyrchan C, Chang HF, Rönn R, Chapman D, Ullah V, Nikitidis G, Glader P, Käck H, Bonn B, Wågberg F, Björkstrand E, Andersson U, Swedin L, Rohman M, Andreasson T, Bergström EL, Jiang F, Zhou XH, Lundqvist AJ, Malmberg A, Ek M, Gordon E, Pettersen A, Ripa L, Davis AM.

J Med Chem. 2019 Sep 12;62(17):7769-7787. doi: 10.1021/acs.jmedchem.9b00555. Epub 2019 Aug 30.

PMID:
31415176
2.

Predictors of Success for Pelvic Floor Muscle Training in Pelvic Organ Prolapse.

Wiegersma M, Panman CMCR, Hesselink LC, Malmberg AGA, Berger MY, Kollen BJ, Dekker JH.

Phys Ther. 2019 Jan 1;99(1):109-117. doi: 10.1093/ptj/pzy114.

PMID:
30329105
4.

Degarelix Versus Goserelin Plus Bicalutamide in the Short-Term Relief of Lower Urinary Tract Symptoms in Prostate Cancer Patients: Results of a Pooled Analysis.

Mason M, Richaud P, Bosnyak Z, Malmberg A, Neijber A.

Low Urin Tract Symptoms. 2017 May;9(2):82-88. doi: 10.1111/luts.12114. Epub 2015 Oct 7.

PMID:
28394498
5.

Low-dose desmopressin combined with serum sodium monitoring can prevent clinically significant hyponatraemia in patients treated for nocturia.

Juul KV, Malmberg A, van der Meulen E, Walle JV, Nørgaard JP.

BJU Int. 2017 May;119(5):776-784. doi: 10.1111/bju.13718. Epub 2016 Dec 10.

6.
7.

Factors Predicting the Off-treatment Duration in Patients with Prostate Cancer Receiving Degarelix as Intermittent Androgen Deprivation Therapy.

Abrahamsson PA, Boccon-Gibod L, Morote J, de Jong IJ, Malmberg A, Neijber A, Albers P.

Eur Urol Focus. 2017 Oct;3(4-5):470-479. doi: 10.1016/j.euf.2015.12.008. Epub 2016 Jan 22.

PMID:
28753747
8.

Inhibition of Inactive States of Tetrodotoxin-Sensitive Sodium Channels Reduces Spontaneous Firing of C-Fiber Nociceptors and Produces Analgesia in Formalin and Complete Freund's Adjuvant Models of Pain.

Matson DJ, Hamamoto DT, Bregman H, Cooke M, DiMauro EF, Huang L, Johnson D, Li X, McDermott J, Morgan C, Wilenkin B, Malmberg AB, McDonough SI, Simone DA.

PLoS One. 2015 Sep 17;10(9):e0138140. doi: 10.1371/journal.pone.0138140. eCollection 2015.

9.

Quantifying observational evidence for risk of fatal and nonfatal cardiovascular disease following androgen deprivation therapy for prostate cancer: a meta-analysis.

Bosco C, Bosnyak Z, Malmberg A, Adolfsson J, Keating NL, Van Hemelrijck M.

Eur Urol. 2015 Sep;68(3):386-96. doi: 10.1016/j.eururo.2014.11.039. Epub 2014 Dec 5. Review.

10.

Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain.

Gingras J, Smith S, Matson DJ, Johnson D, Nye K, Couture L, Feric E, Yin R, Moyer BD, Peterson ML, Rottman JB, Beiler RJ, Malmberg AB, McDonough SI.

PLoS One. 2014 Sep 4;9(9):e105895. doi: 10.1371/journal.pone.0105895. eCollection 2014.

11.

Degarelix as an intermittent androgen deprivation therapy for one or more treatment cycles in patients with prostate cancer.

Boccon-Gibod L, Albers P, Morote J, van Poppel H, de la Rosette J, Villers A, Malmberg A, Neijber A, Montorsi F.

Eur Urol. 2014 Oct;66(4):655-63. doi: 10.1016/j.eururo.2014.05.037. Epub 2014 Jun 18.

PMID:
24954791
12.

Long-term tolerability and efficacy of degarelix: 5-year results from a phase III extension trial with a 1-arm crossover from leuprolide to degarelix.

Crawford ED, Shore ND, Moul JW, Tombal B, Schröder FH, Miller K, Boccon-Gibod L, Malmberg A, Olesen TK, Persson BE, Klotz L.

Urology. 2014 May;83(5):1122-8. doi: 10.1016/j.urology.2014.01.013. Epub 2014 Mar 22.

PMID:
24661333
13.

Disease control outcomes from analysis of pooled individual patient data from five comparative randomised clinical trials of degarelix versus luteinising hormone-releasing hormone agonists.

Klotz L, Miller K, Crawford ED, Shore N, Tombal B, Karup C, Malmberg A, Persson BE.

Eur Urol. 2014 Dec;66(6):1101-8. doi: 10.1016/j.eururo.2013.12.063. Epub 2014 Jan 9.

PMID:
24440304
14.

Substituted 7-amino-5-thio-thiazolo[4,5-d]pyrimidines as potent and selective antagonists of the fractalkine receptor (CX3CR1).

Karlström S, Nordvall G, Sohn D, Hettman A, Turek D, Åhlin K, Kers A, Claesson M, Slivo C, Lo-Alfredsson Y, Petersson C, Bessidskaia G, Svensson PH, Rein T, Jerning E, Malmberg Å, Ahlgen C, Ray C, Vares L, Ivanov V, Johansson R.

J Med Chem. 2013 Apr 25;56(8):3177-90. doi: 10.1021/jm3012273. Epub 2013 Apr 4.

PMID:
23516963
15.

Alzheimer's disease: presenilin 2-sparing γ-secretase inhibition is a tolerable Aβ peptide-lowering strategy.

Borgegård T, Gustavsson S, Nilsson C, Parpal S, Klintenberg R, Berg AL, Rosqvist S, Serneels L, Svensson S, Olsson F, Jin S, Yan H, Wanngren J, Jureus A, Ridderstad-Wollberg A, Wollberg P, Stockling K, Karlström H, Malmberg A, Lund J, Arvidsson PI, De Strooper B, Lendahl U, Lundkvist J.

J Neurosci. 2012 Nov 28;32(48):17297-305. doi: 10.1523/JNEUROSCI.1451-12.2012.

16.

Identification of novel NaV1.7 antagonists using high throughput screening platforms.

Klement G, Babich O, Larsson O, Lund PE, Malmberg A, Sandberg L, Sands ZA, Dabrowski M.

Comb Chem High Throughput Screen. 2012 Nov;15(9):713-20.

PMID:
22934951
17.

Discovery and optimization of aminopyrimidinones as potent and state-dependent Nav1.7 antagonists.

Nguyen HN, Bregman H, Buchanan JL, Du B, Feric E, Huang L, Li X, Ligutti J, Liu D, Malmberg AB, Matson DJ, McDermott JS, Patel VF, Wilenkin B, Zou A, McDonough SI, Dimauro EF.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1055-60. doi: 10.1016/j.bmcl.2011.11.111. Epub 2011 Dec 6.

PMID:
22209205
18.

Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.

Bregman H, Berry L, Buchanan JL, Chen A, Du B, Feric E, Hierl M, Huang L, Immke D, Janosky B, Johnson D, Li X, Ligutti J, Liu D, Malmberg A, Matson D, McDermott J, Miu P, Nguyen HN, Patel VF, Waldon D, Wilenkin B, Zheng XM, Zou A, McDonough SI, DiMauro EF.

J Med Chem. 2011 Jul 14;54(13):4427-45. doi: 10.1021/jm200018k. Epub 2011 Jun 2.

PMID:
21634377
19.

Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain.

Gao B, Hierl M, Clarkin K, Juan T, Nguyen H, Valk Mv, Deng H, Guo W, Lehto SG, Matson D, McDermott JS, Knop J, Gaida K, Cao L, Waldon D, Albrecht BK, Boezio AA, Copeland KW, Harmange JC, Springer SK, Malmberg AB, McDonough SI.

Pain. 2010 Apr;149(1):33-49. doi: 10.1016/j.pain.2010.01.007. Epub 2010 Feb 18.

PMID:
20167427
20.

Synthesis and activity of substituted carbamates as potentiators of the alpha4beta2 nicotinic acetylcholine receptor.

Springer SK, Woodin KS, Berry V, Boezio AA, Cao L, Clarkin K, Harmange JC, Hierl M, Knop J, Malmberg AB, McDermott JS, Nguyen HQ, Waldon D, Albrecht BK, McDonough SI.

Bioorg Med Chem Lett. 2008 Oct 15;18(20):5643-7. doi: 10.1016/j.bmcl.2008.08.092. Epub 2008 Aug 29. Erratum in: Bioorg Med Chem Lett. 2009 Aug 1;19(15):4516. Woodin, Katrina S [added].

PMID:
18805006
21.

Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant alpha4beta2 nicotinic acetylcholine receptor potentiators.

Albrecht BK, Berry V, Boezio AA, Cao L, Clarkin K, Guo W, Harmange JC, Hierl M, Huang L, Janosky B, Knop J, Malmberg A, McDermott JS, Nguyen HQ, Springer SK, Waldon D, Woodin K, McDonough SI.

Bioorg Med Chem Lett. 2008 Oct 1;18(19):5209-12. doi: 10.1016/j.bmcl.2008.08.080. Epub 2008 Aug 28.

PMID:
18789861
22.

Models of nociception: hot-plate, tail-flick, and formalin tests in rodents.

Bannon AW, Malmberg AB.

Curr Protoc Neurosci. 2007 Oct;Chapter 8:Unit 8.9. doi: 10.1002/0471142301.ns0809s41.

PMID:
18428666
23.

Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.

Hawkinson JE, Szoke BG, Garofalo AW, Hom DS, Zhang H, Dreyer M, Fukuda JY, Chen L, Samant B, Simmonds S, Zeitz KP, Wadsworth A, Liao A, Chavez RA, Zmolek W, Ruslim L, Bova MP, Holcomb R, Butelman ER, Ko MC, Malmberg AB.

J Pharmacol Exp Ther. 2007 Aug;322(2):619-30. Epub 2007 Apr 30.

PMID:
17470643
24.

Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats.

Malmberg AB, O'Connor WT, Glennon JC, Ceseña R, Calcutt NA.

Brain Res. 2006 Oct 18;1115(1):48-53. Epub 2006 Aug 22.

PMID:
16920081
25.

Phenylketonuria screening registry as a resource for population genetic studies.

Hannelius U, Lindgren CM, Melén E, Malmberg A, von Dobeln U, Kere J.

J Med Genet. 2005 Oct;42(10):e60.

26.

Molecular pain, a new era of pain research and medicine.

Gu J, Zhuo M, Caterina M, MacDermott AB, Malmberg A, Neugebauer V, Yoshimura M.

Mol Pain. 2005 Jan 14;1:1.

27.

In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.

Ahlgren C, Eriksson A, Tellefors P, Ross SB, Stenfors C, Malmberg A.

Eur J Pharmacol. 2004 Sep 19;499(1-2):67-75.

PMID:
15363952
28.

Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch.

Malmberg AB, Mizisin AP, Calcutt NA, von Stein T, Robbins WR, Bley KR.

Pain. 2004 Oct;111(3):360-7.

PMID:
15363880
29.

Suicide in doctors. A psychological autopsy study.

Hawton K, Malmberg A, Simkin S.

J Psychosom Res. 2004 Jul;57(1):1-4.

PMID:
15256288
30.

Differential expression of the chemokine receptors CX3CR1 and CCR1 by microglia and macrophages in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis.

Sunnemark D, Eltayeb S, Wallström E, Appelsved L, Malmberg A, Lassmann H, Ericsson-Dahlstrand A, Piehl F, Olsson T.

Brain Pathol. 2003 Oct;13(4):617-29.

PMID:
14655765
31.

Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease.

Eltayeb S, Sunnemark D, Berg AL, Nordvall G, Malmberg A, Lassmann H, Wallström E, Olsson T, Ericsson-Dahlstrand A.

J Neuroimmunol. 2003 Sep;142(1-2):75-85.

PMID:
14512166
32.

[Why are old people not allowed to die with dignity?].

Malmberg AM.

Lakartidningen. 2002 Dec 5;99(49):5012. Swedish. No abstract available.

PMID:
12522997
33.
34.

Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats.

Freshwater JD, Svensson CI, Malmberg AB, Calcutt NA.

Diabetes. 2002 Jul;51(7):2249-55.

35.

The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors.

Zeitz KP, Guy N, Malmberg AB, Dirajlal S, Martin WJ, Sun L, Bonhaus DW, Stucky CL, Julius D, Basbaum AI.

J Neurosci. 2002 Feb 1;22(3):1010-9.

36.

Reduced development of tolerance to the analgesic effects of morphine and clonidine in PKC gamma mutant mice.

Zeitz KP, Malmberg AB, Gilbert H, Basbaum AI.

Pain. 2001 Dec;94(3):245-53.

PMID:
11731061
37.

The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord.

Chen ZF, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ.

Neuron. 2001 Jul 19;31(1):59-73.

38.
39.

Contribution of alpha(2) receptor subtypes to nerve injury-induced pain and its regulation by dexmedetomidine.

Malmberg AB, Hedley LR, Jasper JR, Hunter JC, Basbaum AI.

Br J Pharmacol. 2001 Apr;132(8):1827-36.

40.

Protein kinase subtypes involved in injury-induced nociception.

Malmberg AB.

Prog Brain Res. 2000;129:51-9. Review. No abstract available.

PMID:
11098681
41.

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice.

Cockayne DA, Hamilton SG, Zhu QM, Dunn PM, Zhong Y, Novakovic S, Malmberg AB, Cain G, Berson A, Kassotakis L, Hedley L, Lachnit WG, Burnstock G, McMahon SB, Ford AP.

Nature. 2000 Oct 26;407(6807):1011-5.

PMID:
11069181
42.

Non-psychotic psychiatric disorder and subsequent risk of schizophrenia. Cohort study.

Lewis G, David AS, Malmberg A, Allebeck P.

Br J Psychiatry. 2000 Nov;177:416-20.

PMID:
11059994
44.

Doctors who kill themselves: a study of the methods used for suicide.

Hawton K, Clements A, Simkin S, Malmberg A.

QJM. 2000 Jun;93(6):351-7.

PMID:
10873184
45.

Impaired nociception and pain sensation in mice lacking the capsaicin receptor.

Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D.

Science. 2000 Apr 14;288(5464):306-13.

46.

Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats.

Calcutt NA, Stiller C, Gustafsson H, Malmberg AB.

Brain Res. 2000 Feb 21;856(1-2):20-7.

PMID:
10677607
47.

Suicide in farmers.

Malmberg A, Simkin S, Hawton K.

Br J Psychiatry. 1999 Aug;175:103-5. No abstract available.

PMID:
10627790
48.

An introductory hospice experience for third-year medical students.

Steen PD, Miller T, Palmer L, Malmberg A, DeKrey C, McManus S, Hachfeld R, Leitch J, Slotnick H, Theige D.

J Cancer Educ. 1999 Fall;14(3):140-3.

PMID:
10512329
49.

Derivatives of (R)-2-amino-5-methoxytetralin: antagonists and inverse agonists at the dopamine D2A receptor.

Höök BB, Brege C, Linnanen T, Mikaels A, Malmberg A, Johansson AM.

Bioorg Med Chem Lett. 1999 Aug 2;9(15):2167-72.

PMID:
10465538
50.

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